Amlodipine combined with Nexavar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Retroperitoneal Haematoma Life Threatening 2/15/2006 86 Female 150 lb 5/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Acute Coronary Syndrome Hospitalization 10/16/2006 69 Male 115 lb 11/10/2006 Physician Austria
Primary
Concomitant
Mental Status Changes Other Serious 1/11/2007 46 Male 3/5/2007 Other Health Professional United States
Primary
Concomitant
Skin Exfoliation Other Serious 1/30/2007 79 Female 3/28/2007 Physician Netherlands
Primary
Concomitant
Vomiting Hospitalization 4/18/2007 73 Female 231 lb 7/23/2007 Germany
Primary
Concomitant
Swelling Face 5/1/2007 56 Male 8/1/2007 United States
Primary
Concomitant
Swelling Face 5/1/2007 56 Male 10/12/2007 United States
Primary
Concomitant
Rash Erythematous Other Serious 1/1/2007 78 Female 179 lb 11/13/2007 Consumer United States
Primary
Concomitant
Polyarthritis Hospitalization 11/1/2007 74 Male 159 lb 3/4/2008 Germany
Primary
Concomitant
Rash Erythematous Other Serious 1/1/2007 78 Female 179 lb 3/21/2008 Consumer United States
Primary
Concomitant
Hypertension Hospitalization 9/19/2007 57 Male 119 lb 4/8/2008 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 10/1/2007 75 Female 185 lb 5/13/2008 Other Health Professional United States
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization 4/28/2008 57 Female 5/23/2008 Physician Netherlands
Primary
Secondary
Concomitant
Polyarthritis Hospitalization 11/1/2007 74 Male 159 lb 5/27/2008 Germany
Primary
Concomitant
Rash Life Threatening 4/20/2008 71 Female 130 lb 7/24/2008 Physician Japan
Primary
Concomitant
Rash Generalised Hospitalization 7/3/2008 57 Female 8/7/2008 Physician Czech Republic
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 3/20/2008 62 Male 154 lb 8/13/2008 Pharmacist United States
Primary
Concomitant
Shock Haemorrhagic Death 7/11/2008 60 Male 198 lb 10/9/2008 Physician Japan
Primary
Concomitant
Rash Generalised 5/15/2008 69 Female 10/13/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 6/1/2008 58 Male 11/17/2008 Netherlands
Primary
Concomitant
Vomiting Other Serious 6/1/2008 58 Male 12/1/2008 Netherlands
Primary
Concomitant
Rash Generalised 5/15/2008 69 Female 12/4/2008 Physician United States
Primary
Concomitant
Rash Generalised 5/15/2008 69 Female 11/3/2008 Physician United States
Primary
Concomitant
Stomatitis Hospitalization 7/2/2008 64 Male 1/16/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/1/2008 58 Male 1/21/2009 Netherlands
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization 4/28/2008 57 Female 146 lb 2/11/2009 Physician Netherlands
Primary
Secondary
Concomitant
Angioedema Hospitalization 8/10/2008 68 Male 3/3/2009 Physician Germany
Primary
Secondary
Concomitant
Angioedema Hospitalization 8/10/2008 68 Male 3/10/2009 Other Health Professional
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 11/20/2008 61 Male 148 lb 3/16/2009 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Life Threatening 4/11/2009 83 Female 108 lb 5/19/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 6/23/2008 76 Male 101 lb 6/8/2009 Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 6/23/2008 76 Male 101 lb 6/12/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 4/1/2009 80 Female 6/26/2009 United States
Primary
Concomitant
Stomatitis Hospitalization 5/29/2009 69 Male 7/8/2009 Physician Japan
Primary
Concomitant
Laboratory Test Abnormal Hospitalization 2/16/2009 81 Male 220 lb 7/9/2009 Germany
Primary
Concomitant
Thrombocytopenia Life Threatening 4/26/2009 88 Male 123 lb 7/17/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/1/2008 67 Male 185 lb 7/21/2009 Physician Germany
Primary
Concomitant
Rash Other Serious 11/20/2008 61 Male 148 lb 7/30/2009 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 6/18/2009 81 Male 123 lb 8/3/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/15/2008 71 Male 121 lb 8/20/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/8/2009 55 Female 112 lb 8/21/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 4/26/2009 88 Male 123 lb 9/3/2009 Physician Japan
Primary
Concomitant
Angioedema Life Threatening 7/1/2008 63 Male 209 lb 9/9/2009 Physician Denmark
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/15/2008 71 Male 121 lb 9/10/2009 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 8/1/2009 74 Male 110 lb 10/6/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 8/17/2009 82 Male 99 lb 10/16/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 6/23/2008 76 Male 101 lb 10/21/2009 Physician Japan
Primary
Concomitant
Renal Disorder Hospitalization 9/7/2009 59 Male 143 lb 11/4/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/3/2009 77 Male 121 lb 11/5/2009 Physician Japan
Primary
Concomitant
Septic Shock Hospitalization 7/17/2009 70 Female 108 lb 11/10/2009 Physician Japan
Primary
Concomitant
Depression Hospitalization 7/17/2009 70 Female 108 lb 11/12/2009 Physician Japan
Primary
Concomitant
Renal Impairment Life Threatening 8/26/2009 71 Male 128 lb 11/24/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 8/19/2009 80 Female 110 lb 12/2/2009 Physician Japan
Primary
Concomitant
Cholangitis Suppurative Death 10/7/2009 71 Female 108 lb 12/3/2009 Physician Japan
Primary
Concomitant
Oesophageal Varices Haemorrhage Other Serious 8/15/2009 59 Male 139 lb 12/3/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/19/2009 56 Male 172 lb 12/3/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 1/13/2009 74 Male 12/22/2009 Consumer France
Primary
Concomitant
Prothrombin Time Abnormal Hospitalization 2/1/2008 80 Male 220 lb 1/8/2010 Germany
Primary
Concomitant
Pyrexia Hospitalization 11/23/2009 80 Male 137 lb 1/25/2010 United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 12/4/2008 63 Female 99 lb 2/2/2010 Physician Japan
Primary
Concomitant
Urinary Tract Infection Death 11/18/2009 79 Male 119 lb 2/9/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 4/26/2009 88 Male 123 lb 2/12/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/1/2008 58 Male 2/16/2010 Netherlands
Primary
Concomitant
Pruritus 12/1/2009 Male 192 lb 2/16/2010 United States
Primary
Concomitant
Rash Other Serious 8/23/2009 74 Male 181 lb 2/17/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 4/26/2009 88 Male 123 lb 2/17/2010 Physician Japan
Primary
Concomitant
Pancreatic Pseudocyst Hospitalization 5/29/2009 60 Male 2/17/2010 Physician Japan
Primary
Concomitant
Lung Infection Death 10/23/2009 78 Male 3/1/2010 Physician Japan
Primary
Concomitant
Pancreatic Pseudocyst Hospitalization 5/29/2009 60 Male 3/2/2010 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 61 Male 148 lb 3/4/2010 Physician Japan
Primary
Concomitant
Depression Hospitalization 8/31/2009 71 Female 108 lb 3/9/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 9/24/2009 60 Male 139 lb 3/12/2010 Physician Japan
Primary
Concomitant
Pancreatic Enzymes Increased Other Serious 7/23/2009 60 Male 146 lb 3/24/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 7/28/2009 79 Male 3/24/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 7/22/2008 61 Male 148 lb 3/31/2010 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 6/23/2008 76 Male 101 lb 4/8/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 5/19/2009 72 Male 165 lb 4/12/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 1/13/2009 74 Male 4/13/2010 Consumer France
Primary
Concomitant
Rash Hospitalization 8/1/2009 74 Male 110 lb 4/14/2010 Physician Japan
Primary
Concomitant
Malaise Hospitalization 2/1/2010 78 Male 115 lb 4/15/2010 Physician Japan
Primary
Concomitant
Pancytopenia Hospitalization 3/3/2010 71 Female 4/19/2010 Physician Japan
Primary
Concomitant
Angioedema Hospitalization 8/10/2008 68 Male 5/11/2010 Germany
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 4/28/2010 79 Male 5/18/2010 Physician Spain
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 4/28/2010 79 Male 5/24/2010 Physician Spain
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Iii Life Threatening 4/11/2009 83 Female 108 lb 6/1/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 5/10/2010 68 Male 150 lb 6/23/2010 Physician Japan
Primary
Secondary
Concomitant
Walking Aid User 6/30/2010 93 Male 7/14/2010 Other Health Professional United States
Primary
Concomitant
Tongue Discolouration Other Serious 10/23/2009 56 Male 238 lb 7/22/2010 United States
Primary
Concomitant
Interacting
Renal Disorder Life Threatening 7/23/2009 68 Male 141 lb 7/27/2010 Physician Japan
Primary
Concomitant
Deafness Bilateral Other Serious 7/25/2010 60 Male 137 lb 8/11/2010 Physician Singapore
Primary
Concomitant
Stomatitis Hospitalization 5/29/2009 69 Male 132 lb 8/12/2010 Physician Japan
Primary
Concomitant
Deafness Bilateral Other Serious 7/25/2010 60 Male 137 lb 8/23/2010 Physician Singapore
Primary
Concomitant
Stomatitis Hospitalization 5/29/2009 69 Male 132 lb 9/8/2010 Physician Japan
Primary
Concomitant
Delirium Other Serious 8/25/2010 76 Male 123 lb 9/20/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/1/2008 58 Male 9/23/2010 Netherlands
Primary
Concomitant
Thyroiditis Other Serious 4/1/2010 53 Female 9/27/2010 Physician Germany
Primary
Secondary
Concomitant
Thyroiditis Other Serious 4/1/2010 53 Female 9/28/2010 Physician Germany
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 5/10/2010 68 Male 150 lb 9/29/2010 Physician Japan
Primary
Secondary
Concomitant
Thyroiditis Other Serious 4/1/2010 53 Female 9/30/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 6/1/2008 58 Male 10/20/2010 Netherlands
Primary
Concomitant
Delirium Other Serious 8/25/2010 76 Male 123 lb 10/21/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/3/2009 77 Male 121 lb 11/5/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/1/2008 58 Male 11/12/2010 Netherlands
Primary
Concomitant
Rash Hospitalization 6/18/2009 81 Male 123 lb 11/16/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/8/2009 56 Male 172 lb 11/18/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 3/27/2010 65 Male 165 lb 11/19/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 2/18/2010 66 Male 119 lb 12/3/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 4/16/2010 70 Male 101 lb 12/23/2010 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Other Serious 5/19/2009 71 Male 163 lb 12/29/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/16/2010 56 Male 148 lb 1/10/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Abdominal Pain Male 1/12/2011 Pharmacist United States
Primary
Concomitant
Leukopenia Hospitalization 10/15/2010 81 Male 90 lb 1/13/2011 Physician Japan
Primary
Concomitant
Aphasia Other Serious 6/1/2008 58 Male 1/27/2011 Other Health Professional Netherlands
Primary
Concomitant
Hepatic Encephalopathy Life Threatening 8/14/2009 59 Male 138 lb 1/28/2011 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 11/4/2010 80 Male 161 lb 2/1/2011 Physician Japan
Primary
Secondary
Concomitant
Hypothyroidism Hospitalization 11/25/2009 69 Female 153 lb 1/28/2011 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 7/23/2009 60 Male 146 lb 2/1/2011 Physician Japan
Primary
Concomitant
Oedema Hospitalization 6/15/2008 71 Male 121 lb 2/9/2011 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 12/16/2010 56 Male 148 lb 2/15/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 11/16/2009 69 Female 154 lb 2/16/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Hospitalization 10/1/2010 84 Male 146 lb 2/9/2011 Physician Japan
Primary
Concomitant
Arterial Thrombosis Limb Life Threatening 8/26/2009 71 Male 128 lb 2/14/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 12/3/2009 74 Male 132 lb 3/3/2011 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 10/15/2010 81 Male 90 lb 3/3/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Death 7/2/2009 68 Male 126 lb 3/8/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 11/20/2008 60 Male 148 lb 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Melaena Other Serious 5/8/2010 71 Male 106 lb 3/10/2011 Physician Japan
Primary
Concomitant
Hypertension Other Serious 12/4/2008 62 Female 99 lb 3/11/2011 Physician Japan
Primary
Concomitant
Rash Other Serious 8/14/2009 59 Male 139 lb 3/15/2011 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 6/1/2008 58 Male 3/16/2011 Other Health Professional Netherlands
Primary
Concomitant
Haemorrhoidal Haemorrhage Other Serious 5/8/2010 71 Male 106 lb 3/17/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 7/13/2010 59 Male 3/21/2011 Physician Japan
Primary
Concomitant
Ascites Hospitalization 1/1/2011 75 Male 134 lb 3/23/2011 Physician Japan
Primary
Concomitant
Cerebellar Haemorrhage Other Serious 6/1/2010 69 Male 115 lb 3/24/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 1/29/2010 75 Male 115 lb 3/24/2011 Pharmacist Japan
Primary
Concomitant
Vomiting Life Threatening 12/16/2010 56 Male 148 lb 3/24/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Malaise Death 9/1/2010 62 Male 174 lb 3/29/2011 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 6/15/2008 76 Male 101 lb 4/1/2011 Physician Japan
Primary
Concomitant
Abdominal Pain Death 7/23/2009 68 Male 140 lb 4/19/2011 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 7/10/2009 73 Male 5/2/2011 Physician Japan
Primary
Concomitant
Skin Necrosis Other Serious 2/23/2011 63 Female 106 lb 5/7/2011 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 5/15/2008 60 Male 150 lb 5/16/2011 Physician Japan
Primary
Concomitant
Encephalopathy Other Serious 5/8/2010 71 Male 106 lb 5/20/2011 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Other Serious 10/28/2010 73 Male 137 lb 5/25/2011 Physician Japan
Primary
Concomitant
Haemorrhoidal Haemorrhage Hospitalization 5/8/2010 71 Male 106 lb 5/25/2011 Physician Japan
Primary
Concomitant
Hepatorenal Failure Hospitalization 7/3/2009 76 Male 119 lb 6/3/2011 Physician Japan
Primary
Concomitant
Lipase Increased Life Threatening 1/14/2009 69 Male 130 lb 6/3/2011 Other Health Professional Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 5/8/2009 68 Male 102 lb 6/3/2011 Physician Japan
Primary
Concomitant
Convulsion Hospitalization 11/25/2010 70 Female 126 lb 6/3/2011 Other Health Professional Spain
Primary
Concomitant
Vomiting Death 5/1/2010 77 Female 6/3/2011 Physician Japan
Primary
Concomitant

Drug Data