Amlodipine combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Other Serious 69 Female 1/11/2005 Canada
Primary
Concomitant
Orthostatic Hypotension Hospitalization 12/26/2005 84 Female 1/27/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Hemiparesis Other Serious 9/1/2004 36 Female 2/6/2006 Physician United Kingdom
Primary
Concomitant
Fall Hospitalization 2/3/2006 73 Female 2/28/2006 Consumer Brazil
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 1/23/2006 74 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Catatonia Hospitalization 3/6/2006 Male 181 lb 3/17/2006 Physician India
Primary
Concomitant
Cholelithiasis Hospitalization 3/13/2006 56 Female 3/21/2006 Physician Brazil
Primary
Secondary
Concomitant
Head Injury Hospitalization 2/3/2006 73 Female 123 lb 3/23/2006 Consumer Brazil
Primary
Secondary
Concomitant
Pancytopenia Other Serious 3/7/2003 Female 126 lb 4/3/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Hospitalization 1/1/2004 71 Female 3/28/2006 Physician Czech Republic
Primary
Concomitant
Hypokinesia Hospitalization 3/6/2006 Male 181 lb 4/7/2006 Physician India
Primary
Concomitant
Renal Failure Acute Other Serious 2/17/2006 75 Male 223 lb 4/5/2006 United Kingdom
Primary
Concomitant
Head Injury Hospitalization 2/3/2006 73 Female 123 lb 4/14/2006 Consumer Brazil
Primary
Secondary
Concomitant
Pain In Extremity Required Intervention 10/14/2004 Male 288 lb 3/29/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/17/2006 75 Male 223 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/22/2006 81 Male 162 lb 5/8/2006
Primary
Secondary
Concomitant
Vomiting Hospitalization 56 Female 5/4/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 11/22/2005 71 Male 194 lb 5/9/2006 Physician Belgium
Primary
Concomitant
Pancytopenia Other Serious 2/24/2006 64 Female 5/9/2006 Physician Spain
Primary
Concomitant
Thrombosis Hospitalization 12/1/2005 58 Female 211 lb 12/26/2005 Pharmacist United States
Primary
Concomitant
Surgical Procedure Repeated Hospitalization 61 Male 4/28/2006 Physician Czech Republic
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/22/2006 81 Male 162 lb 5/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 9/1/2005 71 Female 158 lb 5/17/2006 Canada
Primary
Concomitant
Somnolence Hospitalization 3/21/2006 63 Female 220 lb 5/12/2006 United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 12/16/2004 75 Male 5/23/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 56 Female 5/19/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2005 47 Male 6/8/2006 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 4/12/2006 70 Male 6/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombosis In Device Hospitalization 60 Male 207 lb 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 2/23/2006 75 Male 7/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Angioneurotic Oedema Life Threatening 6/9/2006 72 Female 144 lb 6/14/2006 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Disability 2/8/2005 47 Male 7/20/2006 Physician Canada
Primary
Concomitant
Sudden Death Death 6/3/2006 75 Female 132 lb 7/18/2006 Physician Netherlands
Primary
Concomitant
Insomnia 3/31/2006 78 Female 198 lb 7/12/2006 Consumer United States
Primary
Concomitant
Cholecystitis Hospitalization 1/16/2006 56 Female 8/23/2006 Physician Brazil
Primary
Secondary
Concomitant
Knee Arthroplasty Hospitalization 8/24/2006 76 Female 9/1/2006 Pharmacist United States
Primary
Concomitant
Tongue Coated Life Threatening 9/24/2006 76 Female 154 lb 10/7/2006 Physician Canada
Primary
Concomitant
Tongue Coated Life Threatening 9/27/2006 76 Female 154 lb 10/10/2006 Physician Canada
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/21/2006 51 Female 139 lb 10/19/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/9/2006 70 Male 10/18/2006 United Kingdom
Primary
Concomitant
Metabolic Acidosis Life Threatening 9/21/2006 71 Female 165 lb 11/6/2006 United Kingdom
Primary
Concomitant
Megakaryocytes Increased Other Serious 10/16/2006 55 Female 11/20/2006 Other Health Professional Denmark
Primary
Concomitant
Completed Suicide Death 47 11/28/2006 Physician United States
Primary
Secondary
Hypertensive Crisis Other Serious 9/29/2006 54 Female 251 lb 1/25/2007 Physician Germany
Primary
Concomitant
Procedural Pain Other Serious 11/25/2006 74 Female 259 lb 3/30/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Life Threatening 3/3/2007 72 Female 3/31/2007 United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms Disability 1/1/2007 Male 4/10/2007 Physician Germany
Primary
Concomitant
Tachycardia Hospitalization 12/11/2006 Female 243 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
Pancytopenia Life Threatening 1/1/2007 Female 6/20/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/4/2007 73 Female 119 lb 7/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 1/1/2007 Female 9/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 9/10/2007 63 Male 290 lb 10/17/2007 Consumer United Kingdom
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2007 48 Male 328 lb 10/16/2007 Physician United Kingdom
Primary
Concomitant
Hypersensitivity Hospitalization 8/7/2007 57 Male 257 lb 10/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Headache Other Serious 4/1/2007 Female 190 lb 10/25/2007 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/14/2005 52 Female 11/5/2007 Other Health Professional Latvia
Primary
Secondary
Concomitant
Angioedema Life Threatening 8/3/2007 60 Female 11/5/2007 Physician United Kingdom
Primary
Concomitant
Ischaemic Stroke Life Threatening Female 11/6/2007 Physician United Kingdom
Primary
Concomitant
Hyperglycaemia Other Serious 1/1/2001 79 Female 185 lb 12/24/2007 Consumer Brazil
Primary
Secondary
Concomitant
Haematemesis Hospitalization 5/28/2006 Male 12/20/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral 1/1/2008 Female 135 lb 3/15/2008 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 3/12/2007 Male 3/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 6/8/2008 Male 476 lb 6/13/2008 Consumer United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 50 Male 6/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2006 Female 139 lb 6/20/2008 Physician United States
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 70 Female 6/20/2008 Other Health Professional Poland
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 5/19/2008 Male 308 lb 7/10/2008 Consumer United Kingdom
Primary
Concomitant
Oedema Other Serious 1/1/2008 Female 135 lb 7/15/2008 Consumer United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/5/2008 70 Male 181 lb 7/16/2008 Mexico
Primary
Secondary
Concomitant
Fatigue 61 Female 7/24/2008 Consumer United States
Primary
Concomitant
No Adverse Event 2/12/2008 80 Female 174 lb 7/24/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/28/2008 89 Male 6/10/2008
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/28/2008 Female 8/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 4/1/2008 76 Male 194 lb 9/9/2008 Physician Brazil
Primary
Concomitant
Pain In Extremity Hospitalization 68 Male 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 70 Female 9/11/2008 Other Health Professional Poland
Primary
Secondary
Concomitant
Syncope Hospitalization 8/2/2008 Female 165 lb 9/4/2008 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 9/26/2008 58 Female 207 lb 10/16/2008 Consumer Brazil
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 10/10/2008 Female 254 lb 10/16/2008 United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 3/1/2008 79 Female 183 lb 10/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 9/26/2008 58 Female 207 lb 10/28/2008 Physician Brazil
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 10/1/2008 82 Male 11/18/2008 Pharmacist United Kingdom
Primary
Concomitant
Urticaria Life Threatening 67 Male 238 lb 11/26/2008 Consumer United Kingdom
Primary
Concomitant
Infected Skin Ulcer Hospitalization 8/8/2008 12/14/2008 Physician Brazil
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 11/30/2008 69 Female 205 lb 12/31/2008 Physician Germany
Primary
Concomitant
Renal Failure Acute Life Threatening 12/10/2008 56 Male 1/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hallucination Hospitalization 1/7/2009 Female 167 lb 1/8/2009 United States
Primary
Secondary
Concomitant
Drug Toxicity Death 45 Male 1/12/2009 Physician United States
Primary
Secondary
Renal Failure Acute Death 10/11/2008 Male 220 lb 1/15/2009 Germany
Primary
Concomitant
Renal Failure Hospitalization 1/7/2009 81 Male 165 lb 1/16/2009 Physician Australia
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 11/1/2008 56 Male 265 lb 1/16/2009 Physician United Kingdom
Primary
Concomitant
Diabetic Ketoacidosis Life Threatening 3/4/2008 Female 136 lb 1/19/2009 Physician United Kingdom
Primary
Concomitant
Tremor Hospitalization 1/8/2009 1/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/1/2008 56 Male 1/21/2009 Consumer United States
Primary
Concomitant
Myelofibrosis Other Serious 11/25/2008 Male 192 lb 1/26/2009 Physician Canada
Primary
Concomitant
Renal Failure Acute Other Serious 9/24/2008 Male 322 lb 1/30/2009 Consumer United Kingdom
Primary
Concomitant
Osteonecrosis Hospitalization 4/24/2008 69 Male 2/2/2009 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/7/2009 81 Male 165 lb 2/3/2009 Physician Australia
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 11/30/2008 69 Female 205 lb 2/11/2009 Physician Germany
Primary
Concomitant
Intervertebral Disc Displacement Hospitalization 8/26/2008 47 Female 202 lb 2/9/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/8/2009 2/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 66 Male 2/20/2009 Physician Hungary
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 1/1/2008 Female 200 lb 2/20/2009 Physician United States
Primary
Concomitant
Aplastic Anaemia Death 10/15/2008 74 Female 2/23/2009 Other Health Professional Spain
Primary
Secondary
Myocardial Ischaemia Hospitalization 4/1/2004 81 Male 180 lb 2/23/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 1/28/2009 81 Male 165 lb 2/24/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Headache 11/11/2008 Male 2/24/2009 United States
Primary
Concomitant
Flushing Male 2/24/2009 United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/1/2008 Female 220 lb 2/25/2009 Physician United States
Primary
Concomitant
Hysterectomy Other Serious 2/9/2009 37 Female 2/26/2009 Consumer Israel
Primary
Concomitant
Renal Failure Acute Hospitalization 1/7/2009 Male 2/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence 4/1/2008 78 Female 3/4/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 11/15/2008 61 Male 305 lb 3/12/2009 Other Health Professional Sweden
Primary
Concomitant
Renal Failure Hospitalization 11/15/2008 61 Male 305 lb 3/17/2009 Sweden
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 10/1/2008 82 Male 3/24/2009 Pharmacist United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2008 Female 200 lb 3/26/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Death 2/23/2009 Female 3/26/2009 Physician Norway
Primary
Concomitant
Interacting
Hysterectomy Other Serious 2/9/2009 37 Female 4/1/2009 Consumer Israel
Primary
Concomitant
Somnolence Hospitalization 2/3/2009 73 Female 4/7/2009 Physician Switzerland
Primary
Concomitant
Interacting
Respiratory Tract Infection Hospitalization 3/8/2009 Male 143 lb 4/13/2009 Physician India
Primary
Concomitant
Thrombosis Disability 3/14/2009 58 Male 238 lb 4/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/1/2008 Male 146 lb 4/22/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2009 52 Female 4/28/2009 Physician Philippines
Primary
Concomitant
Sepsis Hospitalization 12/30/2008 67 5/8/2009 Physician Norway
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/8/2009 70 5/15/2009 Physician Greece
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/1/2008 Male 146 lb 5/28/2009 Consumer United States
Primary
Secondary
Concomitant
Palpitations Hospitalization 73 Female 5/28/2009 United States
Primary
Concomitant
Post Procedural Haematoma Hospitalization 47 176 lb 6/10/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Death 57 Male 6/17/2009 United States
Primary
Concomitant
Wound Infection Death 63 Male 6/19/2009 United States
Primary
Concomitant
Torsade De Pointes Other Serious 72 Female 6/25/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Pancreatitis Chronic Other Serious 6/1/2009 Female 273 lb 6/25/2009 Physician United States
Primary
Concomitant
Rash Other Serious 12/26/2008 6/30/2009 Other Health Professional Malaysia
Primary
Concomitant
Periorbital Oedema Other Serious 7/1/2008 6/30/2009 Other Health Professional Malaysia
Primary
Concomitant
Vasculitic Rash Other Serious 3/1/2009 64 Female 194 lb 7/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Palpitations Hospitalization 70 Female 7/19/2009 Lawyer United States
Primary
Concomitant
Trismus Other Serious 51 Male 7/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/8/2009 Male 230 lb 7/29/2009 Consumer United States
Primary
Secondary
Concomitant
Extrasystoles Other Serious 6/1/2009 Female 196 lb 7/29/2009 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2005 Female 436 lb 7/29/2009 Consumer United States
Primary
Concomitant
Surgery Hospitalization 5/7/2009 Male 247 lb 7/10/2009 Other Health Professional United States
Primary
Concomitant
Dysphonia Other Serious 6/29/2009 67 7/30/2009 Physician Norway
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 6/18/2009 83 Male 7/30/2009 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 6/16/2009 55 Male 254 lb 7/31/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 6/16/2009 55 Male 254 lb 7/31/2009 United States
Primary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 7/31/2009 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 7/9/2009 81 Female 210 lb 7/31/2009 Consumer United States
Primary
Concomitant
Oral Disorder Death 6/10/2009 70 Male 7/31/2009 Physician Colombia
Primary
Concomitant
Pain Other Serious 1/1/2007 68 Male 7/28/2009 United Kingdom
Primary
Concomitant
Osteonecrosis Hospitalization 4/24/2008 69 Male 8/3/2009 Physician Germany
Primary
Secondary
Concomitant

Drug Data