Amlodipine combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Heart Rate Increased Other Serious 1/1/2003 53 Female 2/7/2006 Consumer Canada
Primary
Concomitant
Ventricular Failure Required Intervention 12/1/2005 Female 2/8/2006 Physician Netherlands
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2005 79 Male 216 lb 2/23/2006 Physician Italy
Primary
Concomitant
Renal Failure Acute Other Serious 2/17/2006 75 Male 3/31/2006 Other Health Professional France
Primary
Concomitant
Epilepsy Hospitalization 5/14/2006 45 Male 6/28/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/17/2006 75 Male 8/8/2006 Denmark
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 55 Male 159 lb 10/6/2006 Canada
Primary
Concomitant
Metabolic Acidosis Required Intervention 9/21/2006 71 Female 11/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 58 Female 280 lb 1/25/2007 Other Health Professional Poland
Primary
Concomitant
Upper Limb Fracture Required Intervention 70 Female 143 lb 4/6/2007 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 73 Female 7/6/2007 United Kingdom
Primary
Concomitant
Vomiting Life Threatening 60 Female 8/29/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 6/13/2006 Female 11/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 11/6/2007 Male 170 lb 11/7/2007 Pharmacist United States
Primary
Concomitant
Arteriospasm Coronary Life Threatening 3/22/2007 77 Female 206 lb 11/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 6/13/2006 Female 11/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 10/19/2007 Male 11/16/2007 Physician Germany
Primary
Concomitant
Eczema Asteatotic Hospitalization 5/23/2007 Female 11/20/2007 United Kingdom
Primary
Concomitant
Cataract Disability 1/1/2005 72 Female 209 lb 3/26/2008 Consumer Turkey
Primary
Secondary
Concomitant
Peripheral Ischaemia Other Serious 2/12/2008 79 Female 4/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Required Intervention 11/30/2002 66 Female 97 lb 6/17/2008 United States
Primary
Concomitant
Vomiting Hospitalization 4/25/2007 75 Female 110 lb 6/17/2008 Physician India
Primary
Concomitant
Glossodynia 9/15/2007 Female 182 lb 7/25/2008 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 7/5/2008 Male 249 lb 8/15/2008 Physician United Kingdom
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 66 Male 10/15/2008 Physician United Kingdom
Primary
Secondary
Pleural Effusion Other Serious 3/1/2008 79 Female 183 lb 10/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 5/5/2008 Male 159 lb 10/20/2008 Consumer United States
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 5/23/2008 Female 115 lb 10/20/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/17/2006 75 Male 10/22/2008 Denmark
Primary
Concomitant
Diarrhoea Other Serious 6/1/2006 54 Male 10/22/2008 United Kingdom
Primary
Concomitant
Surgery Other Serious 11/13/2008 12/10/2008 Consumer Brazil
Primary
Concomitant
Pancreatitis Acute Other Serious 11/24/2008 49 Male 12/9/2008 Physician Germany
Primary
Concomitant
Renal Failure Acute Life Threatening 12/10/2008 56 Male 1/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Completed Suicide Other Serious 1/29/2009 Other Health Professional United States
Primary
Secondary
Surgery Other Serious 11/13/2008 2/19/2009 Consumer Brazil
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Required Intervention 65 Male 4/30/2009 Malaysia
Primary
Concomitant
Somnolence Other Serious 1/1/2008 64 Male 4/24/2009 United States
Primary
Secondary
Concomitant
Social Avoidant Behaviour Death Male 5/22/2009 Lawyer United States
Primary
Concomitant
Drug Administered At Inappropriate Site 4/1/2009 Female 245 lb 6/2/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 49 Female 6/2/2009 Spain
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 2/19/2008 Male 194 lb 6/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Palpitations Other Serious 1/30/2009 61 Female 93 lb 6/5/2009 Other Health Professional Thailand
Primary
Secondary
Concomitant
Hiatus Hernia Other Serious 12/1/2008 62 Female 6/9/2009 Consumer United States
Primary
Concomitant
Sleep Disorder Hospitalization 5/1/2009 82 Male 6/4/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/4/2009 74 Male 170 lb 6/12/2009 Physician Australia
Primary
Secondary
Concomitant
White Blood Cell Disorder Hospitalization 4/15/2009 74 Female 172 lb 6/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 4/1/2004 68 Male 250 lb 6/15/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 4/25/2009 65 Female 139 lb 7/10/2009 Other Health Professional Denmark
Primary
Concomitant
Respiratory Failure Hospitalization 4/1/2009 Female 8/6/2009 Physician United States
Primary
Concomitant
Wound Other Serious 7/28/2009 69 Male 161 lb 8/6/2009 Consumer Brazil
Primary
Concomitant
Vomiting Life Threatening 7/10/2009 71 Female 269 lb 8/19/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 50 Male 8/20/2009 United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/15/2008 Female 9/3/2009 Consumer Australia
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 1/1/2009 Male 10/8/2009 Physician Canada
Primary
Concomitant
Medical Device Implantation Hospitalization 6/1/2009 61 Female 10/14/2009 Consumer Canada
Primary
Concomitant
Paraesthesia Oral Other Serious 10/7/2009 10/30/2009 Physician United Kingdom
Primary
Concomitant
Lid Lag Other Serious 67 12/2/2009 Consumer United States
Primary
Concomitant
Cataract Disability 1/1/2005 72 Female 209 lb 12/1/2009 Consumer Turkey
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2006 Female 139 lb 1/6/2010 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Life Threatening 5/3/2008 86 Female 156 lb 1/5/2010 Pharmacist United States
Primary
Concomitant
Diarrhoea Other Serious Male 1/12/2010 Consumer Brazil
Primary
Concomitant
Quadriparesis Hospitalization 1/1/2010 Female 1/15/2010 Physician Japan
Primary
Secondary
Concomitant
Wheezing Hospitalization 12/14/2009 Female 1/19/2010 United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/6/2010 60 Male 209 lb 2/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 1/6/2010 60 Male 209 lb 2/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Pain Hospitalization 11/8/2009 49 Male 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 79 Male 2/5/2010 United States
Primary
Concomitant
Skin Haemorrhage Other Serious 69 Female 163 lb 2/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 3/2/2010 Physician United Kingdom
Primary
Concomitant
Haemoglobin Decreased Life Threatening 10/13/2009 Female 3/2/2010 Physician Hungary
Primary
Secondary
Concomitant
Underdose Hospitalization 6/1/2009 Male 3/2/2010 Physician United States
Primary
Concomitant
Completed Suicide Death 3/4/2010 Physician United States
Primary
Secondary
Completed Suicide Death 3/4/2010 Physician United States
Primary
Secondary
Feeling Jittery 7/14/2009 50 Male 3/8/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/1993 Female 3/9/2010 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 63 Male 151 lb 3/2/2010
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/18/2007 70 Male 172 lb 3/11/2010 Mexico
Primary
Secondary
Concomitant
Tachycardia Hospitalization 9/1/2009 54 Male 3/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Skin Laceration 3/9/2010 Female 3/18/2010 Consumer
Primary
Concomitant
Pneumonia Aspiration Death 10/6/2009 Male 3/18/2010 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/19/2010 Physician Argentina
Primary
Concomitant
Spinal Cord Disorder Hospitalization 60 Male 176 lb 3/26/2010 Consumer Brazil
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/26/2010 Physician Argentina
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/29/2010 Physician Argentina
Primary
Concomitant
Angioedema Hospitalization 5/1/2009 Female 195 lb 3/29/2010 Consumer United States
Primary
Concomitant
Flatulence 12/1/2009 Male 3/29/2010 Consumer
Primary
Concomitant
Stent Placement Other Serious 1/1/2004 62 Male 212 lb 4/9/2010 Consumer Brazil
Primary
Concomitant
Product Odour Abnormal Other Serious 1/1/2010 78 Female 179 lb 4/23/2010 Consumer United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 1/29/2010 64 Male 160 lb 5/12/2010 Physician United States
Primary
Concomitant
Chest Pain Other Serious 3/12/2009 69 Male 5/12/2009 United States
Primary
Concomitant
Rash Other Serious 11/24/2007 57 Female 194 lb 5/14/2010 Other Health Professional United States
Primary
Concomitant
Angioedema Hospitalization 5/1/2009 34 Female 195 lb 5/14/2010 Consumer United States
Primary
Concomitant
Motor Dysfunction Hospitalization 12/30/2009 66 Male 190 lb 5/17/2010 Physician Switzerland
Primary
Concomitant
Abdominal Pain Lower 2/26/2010 65 Male 5/17/2010 United States
Primary
Concomitant
Blood Glucose Increased 5/1/2010 50 Male 345 lb 5/17/2010 United States
Primary
Concomitant
Urinary Retention Other Serious 1/1/2008 51 Female 230 lb 5/18/2010 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 2/12/2010 60 Male 190 lb 5/19/2010 Other Health Professional Australia
Primary
Concomitant
Splenomegaly Other Serious 53 Male 5/19/2010 Other Health Professional India
Primary
Concomitant
Myocardial Ischaemia Other Serious 4/17/2009 72 Male 186 lb 5/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 2/19/2008 64 Male 194 lb 5/20/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 4/9/2010 50 Male 261 lb 5/18/2010 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 8/23/2008 79 Male 174 lb 5/26/2010 Physician United Kingdom
Primary
Concomitant
Cardiogenic Shock Life Threatening 4/17/2010 74 Male 154 lb 5/27/2010 Physician Germany
Primary
Concomitant
Productive Cough 53 Male 5/28/2010 Consumer United States
Primary
Concomitant
Renal Impairment Required Intervention 2/22/2010 61 Female 6/10/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/16/2010 71 Male 6/21/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 1/14/2009 66 Female 6/24/2010 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 66 Female 6/18/2010 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 4/9/2010 50 Male 261 lb 6/23/2010 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/16/2010 71 Male 7/5/2010 Physician United States
Primary
Concomitant
Paraesthesia 1/1/2008 76 Male 241 lb 8/3/2010 Consumer United States
Primary
Concomitant
Intentional Drug Misuse Death 2/10/2010 76 Female 7/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 219 lb 9/10/2010 Physician United States
Primary
Concomitant
Spinal Disorder Other Serious 1/1/2007 58 Female 255 lb 9/10/2010 Consumer United States
Primary
Concomitant
Pleurisy Hospitalization 78 Female 9/23/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 1/1/2010 61 Female 185 lb 9/15/2010 Consumer United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 2/10/2010 76 Female 9/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 1/1/2010 61 Female 185 lb 9/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tuberculosis Gastrointestinal Hospitalization 1/25/2010 65 Female 93 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 61 Female 238 lb 12/23/2010 Consumer Brazil
Primary
Concomitant
Asthenia Other Serious 1/1/2010 76 Male 165 lb 1/3/2011 Consumer Brazil
Primary
Concomitant
Pleural Effusion Hospitalization 1/25/2010 65 Female 93 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 1/25/2010 65 Female 93 lb 1/24/2011 Physician Japan
Primary
Secondary
Concomitant
Mesothelioma Life Threatening 5/1/2010 81 Male 1/24/2011 Other Health Professional France
Primary
Concomitant
Mesothelioma Malignant Other Serious 5/1/2010 81 Male 1/25/2011 Other Health Professional France
Primary
Concomitant
Haemorrhage Other Serious 1/1/2008 68 Female 240 lb 1/21/2011 United States
Primary
Concomitant
Blood Potassium Decreased Death 1/1/2009 45 Female 1/27/2011 Physician United States
Primary
Secondary
Death Death 2/5/2011 77 Female 227 lb 2/11/2011 Consumer United States
Primary
Secondary
Concomitant
Sudden Death Death 61 Female 319 lb 2/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 1/1/2007 66 Female 136 lb 2/24/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 43 Male 3/6/2011 Other Health Professional United States
Primary
Secondary
Blood Sodium Increased Hospitalization 1/26/2011 69 Male 3/14/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 10/18/2008 70 Male 4/7/2011 Physician Switzerland
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 1/26/2011 69 Male 3/29/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 46 Male 214 lb 4/13/2011 Physician Poland
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 46 Male 214 lb 4/14/2011 Physician Poland
Primary
Concomitant
Vomiting Life Threatening 1/11/2011 76 Male 4/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/1/2011 76 Male 4/18/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/26/2011 69 Male 4/7/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Conjunctivitis 9/30/2010 59 Male 5/3/2011 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 2/26/2011 55 Female 131 lb 5/3/2011 Physician United States
Primary
Secondary
Concomitant
Cholecystectomy Other Serious 1/1/2002 60 Female 170 lb 5/3/2011 Consumer United States
Primary
Concomitant
Pneumonia Death 3/2/2011 51 Female 256 lb 5/4/2011 Physician Hungary
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection 9/1/2010 60 Female 2/24/2011 Other Health Professional United States
Primary
Concomitant
Atrial Thrombosis Other Serious 57 6/9/2011 Other Health Professional Brazil
Primary
Concomitant
Multi-organ Failure Hospitalization 11/27/2006 66 Female 6/4/2011 Consumer Brazil
Primary
Concomitant
Pain Female 236 lb 7/19/2011 Consumer United States
Primary
Concomitant
Abdominal Discomfort Life Threatening 68 Male 7/26/2011 Japan
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 64 Male 8/11/2011 Other Health Professional France
Primary
Secondary
Duodenal Ulcer Hospitalization 3/10/2011 82 Male 172 lb 8/22/2011 Other Health Professional Canada
Primary
Secondary
Concomitant

Drug Data