Amlodipine combined with Marcumar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Retroperitoneal Haemorrhage Death 6/17/2006 68 Female 170 lb 7/11/2006 Physician Belgium
Primary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 6/1/2006 68 Female 170 lb 7/27/2006 Physician Belgium
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 6/26/2006 78 Female 110 lb 8/21/2006 Physician Germany
Primary
Concomitant
Transaminases Increased Hospitalization 9/8/2006 61 Male 1/11/2007 Physician Germany
Primary
Concomitant
Grand Mal Convulsion Hospitalization 9/23/2006 Male 2/23/2007 Physician Germany
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 9/23/2006 Male 2/28/2007 Physician Germany
Primary
Secondary
Concomitant
Rash Hospitalization 1/21/2007 66 Female 2/26/2007 Physician Germany
Primary
Concomitant
Nephrotic Syndrome Other Serious 2/20/2007 Male 5/15/2007 Physician Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 4/16/2007 73 Male 207 lb 6/26/2007 Physician Switzerland
Primary
Concomitant
Oedema Peripheral Hospitalization 5/2/2007 68 Female 176 lb 6/29/2007 Physician Germany
Primary
Secondary
Concomitant
Myositis Hospitalization 1/1/2007 Male 231 lb 2/12/2008 Physician Germany
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 1/1/2001 Male 3/17/2008 Physician Germany
Primary
Concomitant
Weight Increased Disability 1/1/2007 70 Male 251 lb 4/14/2008 Pharmacist Germany
Primary
Concomitant
Gait Disturbance Hospitalization 11/4/2004 Female 4/21/2008 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 70 Male 256 lb 5/8/2008 Pharmacist Germany
Primary
Concomitant
Spinal Osteoarthritis Other Serious 1/1/2001 Male 8/19/2008 Consumer Germany
Primary
Concomitant
Postmenopausal Haemorrhage Other Serious 7/31/2008 Female 168 lb 9/8/2008 Physician Netherlands
Primary
Concomitant
Pulmonary Embolism Other Serious 5/29/2008 Male 9/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 4/24/2008 69 Male 2/2/2009 Physician Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious Female 3/17/2009 Consumer Austria
Primary
Concomitant
Interacting
Sluggishness Other Serious 1/1/2009 81 Female 150 lb 3/20/2009 Consumer Germany
Primary
Concomitant
Vomiting Other Serious 1/1/2009 81 Female 150 lb 4/17/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening Female 183 lb 5/1/2009 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious Female 6/4/2009 Physician Austria
Primary
Concomitant
Interacting
Multi-organ Disorder Death 11/26/2008 Male 265 lb 5/29/2009 Germany
Primary
Concomitant
Hyperthyroidism Hospitalization 10/30/2008 Male 265 lb 5/29/2009 Physician Germany
Primary
Concomitant
Syncope Death 75 Male 6/29/2009 Physician Germany
Primary
Secondary
Concomitant
Laboratory Test Abnormal Hospitalization 2/16/2009 81 Male 220 lb 7/9/2009 Germany
Primary
Concomitant
Osteonecrosis Hospitalization 4/24/2008 69 Male 8/3/2009 Physician Germany
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 2/5/2009 Female 8/10/2009 Physician Germany
Primary
Concomitant
Vertigo Other Serious 72 Female 8/19/2009 Physician Germany
Primary
Secondary
Torsade De Pointes Other Serious 2/27/2009 Male 9/21/2009 Physician Germany
Primary
Secondary
Concomitant
Vertigo Other Serious 72 Female 9/25/2009 Physician Germany
Primary
Secondary
Vertigo Other Serious 72 Female 9/25/2009 Physician Germany
Primary
Secondary
Vertigo Other Serious 10/23/2009 70 Male 11/16/2009 Consumer Germany
Primary
Concomitant
Transaminases Increased Hospitalization 4/18/2009 66 Female 11/20/2009 Other Health Professional Germany
Primary
Concomitant
Interacting
Splenomegaly Other Serious 66 Female 213 lb 11/18/2009 Physician Germany
Primary
Secondary
Concomitant
Vertigo Other Serious 10/31/2009 70 Male 309 lb 12/11/2009 Physician Germany
Primary
Concomitant
Right Ventricular Failure Hospitalization 2/5/2009 Female 12/11/2009 Physician Germany
Primary
Concomitant
Splenomegaly Other Serious 66 Female 213 lb 12/10/2009 Physician Germany
Primary
Secondary
Concomitant
Percutaneous Coronary Intervention Other Serious 2/1/2009 Male 229 lb 12/16/2009 Physician Germany
Primary
Concomitant
Vertigo Other Serious 10/31/2009 Male 309 lb 12/23/2009 Physician Germany
Primary
Concomitant
Percutaneous Coronary Intervention Other Serious 1/19/2009 Male 229 lb 1/4/2010 Physician Germany
Primary
Concomitant
Prothrombin Time Abnormal Hospitalization 2/1/2008 80 Male 220 lb 1/8/2010 Germany
Primary
Concomitant
Transaminases Increased Other Serious 4/18/2009 66 Female 1/13/2010 France
Primary
Concomitant
Interacting
Urosepsis Life Threatening 10/14/2009 Female 123 lb 1/14/2010 Physician Germany
Primary
Concomitant
Splenomegaly Other Serious 66 Female 213 lb 1/15/2010 Physician Germany
Primary
Secondary
Concomitant
Skin Cancer Hospitalization 4/24/2008 69 Male 2/2/2010 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Oedema Death 11/26/2008 Male 265 lb 2/1/2010 Germany
Primary
Concomitant
General Physical Health Deterioration Hospitalization 6/29/2009 Female 172 lb 3/10/2010 Physician Germany
Primary
Concomitant
Renal Failure Acute Other Serious Female 3/15/2010 Physician Germany
Primary
Concomitant
Dyspnoea Life Threatening 2/12/2010 75 Male 198 lb 3/18/2010 Physician Switzerland
Primary
Concomitant
Diarrhoea Other Serious 1/1/2010 Male 3/26/2010 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 12/1/2009 72 Male 4/9/2010 Consumer Germany
Primary
Concomitant
Right Ventricular Failure Hospitalization 2/5/2009 61 Female 5/10/2010 Physician Germany
Primary
Concomitant
Personality Change Other Serious 79 Female 159 lb 5/21/2010 Pharmacist Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 4/11/2010 82 Female 218 lb 6/2/2010 Pharmacist
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/17/2010 81 Male 6/16/2010 Physician Switzerland
Primary
Concomitant
International Normalised Ratio Increased Other Serious 4/27/2010 6/17/2010 Physician Italy
Primary
Secondary
Concomitant
Spinal Fracture Hospitalization 80 Female 198 lb 6/18/2010
Primary
Concomitant
Osteoporotic Fracture Hospitalization 5/26/2010 81 Female 198 lb 6/30/2010
Primary
Concomitant
Personality Change Other Serious 79 Female 159 lb 7/2/2010 Pharmacist Germany
Primary
Concomitant
Prothrombin Time Prolonged Other Serious Male 7/13/2010 Consumer Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/23/2010 32 Female 168 lb 7/21/2010 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious 2/1/2010 80 Male 132 lb 7/23/2010 Physician Switzerland
Primary
Concomitant
Skin Ulcer Hospitalization 4/24/2008 69 Male 7/29/2010 Physician Germany
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 4/24/2008 69 Male 8/3/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/30/2010 Male 8/4/2010 Physician Switzerland
Primary
Concomitant
Hypoglycaemia Life Threatening 1/12/2010 71 Male 170 lb 8/9/2010 Physician Germany
Primary
Concomitant
Torsade De Pointes Other Serious 2/27/2009 74 Male 8/17/2010 Physician Germany
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 8/31/2010 50 Male 9/14/2010 Consumer Denmark
Primary
Secondary
Withdrawal Syndrome Other Serious 5/1/2010 81 Female 183 lb 9/21/2010 Physician Germany
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 12/23/2009 73 Female 9/23/2010 Physician Germany
Primary
Concomitant
Hypertensive Heart Disease Hospitalization 9/10/2009 70 Male 271 lb 9/27/2010 Physician Germany
Primary
Concomitant
Varicose Vein Other Serious 1/1/2009 69 Female 198 lb 9/27/2010 Physician Germany
Primary
Secondary
Concomitant
Varicose Vein Other Serious 1/1/2009 69 Female 207 lb 10/7/2010 Physician Germany
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 5/1/2010 81 Female 183 lb 10/17/2010 Physician Germany
Primary
Concomitant
Urosepsis Life Threatening 10/14/2009 74 Female 123 lb 11/8/2010 Physician Germany
Primary
Concomitant
Nausea Other Serious 6/28/2010 70 Female 134 lb 11/10/2010 Physician Germany
Primary
Concomitant
Ventricular Tachycardia Hospitalization 9/27/2010 73 Male 209 lb 11/15/2010 Physician Germany
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 11/6/2010 79 Female 123 lb 11/29/2010 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 4/27/2010 92 Female 11/29/2010 Physician Germany
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 11/26/2008 74 Male 265 lb 11/24/2010 Other Health Professional Germany
Primary
Concomitant
Renal Failure Other Serious 10/21/2010 57 Male 12/22/2010 Physician Germany
Primary
Concomitant
Condition Aggravated Other Serious 10/21/2010 57 Male 287 lb 1/19/2011 Physician Germany
Primary
Concomitant
Leukoencephalopathy Hospitalization 10/22/2010 75 Female 1/7/2011 Other Health Professional Germany
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2011 76 Female 2/1/2011 Physician Germany
Primary
Concomitant
Unevaluable Event Other Serious 10/22/2010 75 Female 1/21/2011 Other Health Professional Germany
Primary
Concomitant
Carotid Artery Stenosis Other Serious 10/22/2010 75 Female 1/25/2011 Other Health Professional Germany
Primary
Concomitant
Arthralgia Hospitalization 12/23/2009 73 Female 2/8/2011 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 11/11/2010 87 Female 170 lb 2/15/2011 Consumer Germany
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 11/11/2010 87 Female 170 lb 2/22/2011 Consumer Germany
Primary
Secondary
Concomitant
Aortic Thrombosis Life Threatening 1/19/2010 63 Male 203 lb 3/3/2011 Physician Germany
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/1/2011 76 Female 3/9/2011 Physician Germany
Primary
Concomitant
Bladder Cancer Hospitalization 11/23/2010 75 Male 3/15/2011 Other Health Professional Germany
Primary
Concomitant
Renal Failure Other Serious 11/11/2010 87 Female 170 lb 3/18/2011 Consumer Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization Male 4/12/2011 Consumer Germany
Primary
Concomitant
Rheumatoid Arthritis Hospitalization Male 5/4/2011 Consumer Germany
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 8/9/2010 55 Female 229 lb 5/19/2011 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/30/2008 74 Male 265 lb 5/11/2011 Other Health Professional Germany
Primary
Concomitant
Arthralgia Disability 4/1/2011 48 Male 192 lb 5/13/2011 Other Health Professional Germany
Primary
Concomitant
Drug Effect Increased Life Threatening 11/8/2010 80 Female 143 lb 5/26/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Drug Eruption Hospitalization 3/1/2011 Female 159 lb 5/27/2011 Physician Germany
Primary
Concomitant
Cerebral Haemorrhage Hospitalization Male 6/2/2011 Consumer Germany
Primary
Concomitant
Drug Interaction Life Threatening 11/8/2010 80 Female 143 lb 6/7/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Drug Effect Increased Life Threatening 11/8/2010 80 Female 143 lb 6/7/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Drug Interaction Life Threatening 11/8/2010 80 Female 5/24/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 11/8/2010 80 Female 143 lb 6/8/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Prothrombin Time Prolonged Life Threatening 11/8/2010 80 Female 6/7/2011 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Death 3/1/2009 78 Female 6/10/2011 Switzerland
Primary
Secondary
Concomitant
Bone Infarction Disability 4/1/2011 47 Male 192 lb 6/27/2011 Physician Germany
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 5/17/2011 63 143 lb 6/29/2011 Physician Germany
Primary
Concomitant
Drug Eruption Hospitalization 3/1/2011 Female 159 lb 6/29/2011 Physician Germany
Primary
Concomitant
Bone Infarction Disability 4/1/2011 47 Male 192 lb 7/6/2011 Physician Germany
Primary
Concomitant
Atrial Flutter Hospitalization 11/9/2009 66 Male 168 lb 7/13/2011 Physician Germany
Primary
Secondary
Concomitant
Bone Infarction Disability 4/1/2011 47 Male 192 lb 7/15/2011 Physician Germany
Primary
Concomitant
Cerebrovascular Accident Hospitalization Male 8/2/2011 Consumer Germany
Primary
Concomitant
Crohn's Disease Other Serious 1/1/2004 34 Male 117 lb 8/8/2011 Consumer Germany
Primary
Concomitant
Aortic Dissection Other Serious 7/1/2005 35 Male 117 lb 8/11/2011 Consumer Germany
Primary
Concomitant
Drug Effect Increased Life Threatening 11/8/2010 80 Female 143 lb 8/12/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Erysipelas Other Serious 8/9/2010 55 Female 229 lb 8/31/2011 Physician Germany
Primary
Concomitant
Ileus Paralytic Death 4/27/2011 76 Male 9/14/2011 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 6/1/2011 76 Male 203 lb 9/20/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/4/2010 80 Female 159 lb 9/26/2011 Other Health Professional Germany
Primary
Concomitant
Angina Pectoris Hospitalization 11/9/2009 66 Male 168 lb 10/4/2011 Physician Germany
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 10/22/2010 75 Female 10/5/2011 Physician Germany
Primary
Concomitant
Hyperuricaemia Hospitalization 5/17/2011 84 Female 194 lb 10/28/2011 Physician Germany
Primary
Concomitant
Oesophagitis Hospitalization 1/1/2011 67 Female 229 lb 11/7/2011 Physician Germany
Primary
Secondary
Concomitant
Activated Partial Thromboplastin Time Prolonged Hospitalization 9/24/2011 75 Male 163 lb 11/7/2011 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/30/2008 74 Male 265 lb 11/16/2011 Physician Germany
Primary
Concomitant
Bone Infarction Disability 3/1/2011 47 Male 192 lb 11/22/2011 Physician Germany
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Hospitalization 5/17/2011 84 Female 194 lb 11/24/2011 Physician Germany
Primary
Concomitant
Oesophagitis Hospitalization 1/1/2011 67 Female 229 lb 12/2/2011 Physician Germany
Primary
Secondary
Concomitant
Angina Pectoris Other Serious Male 12/14/2011 Germany
Primary
Concomitant
Retinal Artery Occlusion Other Serious 10/22/2010 75 Female 2/17/2012 Physician Germany
Primary
Concomitant
Gastroenteritis Norovirus Hospitalization 11/14/2011 76 Female 139 lb 2/22/2012 Consumer Germany
Primary
Concomitant
Renal Impairment Other Serious 1/1/2009 77 Female 2/22/2012 Consumer Germany
Primary
Concomitant
Fatigue Other Serious 9/18/2011 Male 176 lb 3/7/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Rash Hospitalization 3/1/2011 Female 159 lb 3/21/2012 Physician Germany
Primary
Concomitant
Cardiac Failure Hospitalization 10/30/2008 74 Male 265 lb 3/22/2012 Physician Germany
Primary
Concomitant
Haemoglobin Decreased Other Serious 9/18/2011 Male 176 lb 3/23/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Blood Potassium Increased Other Serious 4/27/2011 82 Male 4/13/2012 Physician Germany
Primary
Concomitant
Cardiac Disorder Life Threatening 2/20/2012 81 Female 120 lb 4/26/2012 Physician Germany
Primary
Concomitant
Melaena Hospitalization 9/1/2009 84 Male 185 lb 5/2/2012 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Interacting
Cholelithiasis Hospitalization 9/1/2009 84 Male 185 lb 5/7/2012 Pharmacist Switzerland
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 4/27/2011 82 Male 181 lb 5/10/2012 Physician Germany
Primary
Secondary
Concomitant
Haemoperfusion Death 1/1/2009 5/30/2012 Consumer Germany
Primary
Concomitant
Renal Failure Acute Other Serious 3/3/2010 33 Male 6/7/2012 Physician Belgium
Primary
Secondary
Concomitant
Cardiac Failure Death 11/26/2008 74 Male 265 lb 6/14/2012 Physician Germany
Primary
Concomitant
Cardiac Failure Death 10/30/2008 74 Male 265 lb 6/14/2012 Physician Germany
Primary
Concomitant

Drug Data