Amlodipine combined with Loxonin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cellulitis Staphylococcal Hospitalization 6/25/2005 Female 2/10/2006 Physician Japan
Primary
Secondary
Concomitant
Enterocolitis Haemorrhagic Other Serious 3/4/2006 36 Female 1/8/2007 Consumer Japan
Primary
Concomitant
Enterocolitis Haemorrhagic Other Serious 3/4/2006 36 Female 1/25/2007 Consumer Japan
Primary
Concomitant
Enterocolitis Haemorrhagic Other Serious 3/4/2006 36 Female 1/29/2007 Consumer Japan
Primary
Concomitant
Enterocolitis Haemorrhagic Other Serious 3/4/2006 36 Female 1/31/2007 Consumer Japan
Primary
Concomitant
Lip Erosion Other Serious 11/23/2006 75 Female 2/22/2007 Physician Japan
Primary
Concomitant
Enterocolitis Haemorrhagic Other Serious 3/4/2006 36 Female 2/28/2007 Consumer Japan
Primary
Concomitant
Hypoglycaemic Coma Life Threatening 7/7/2007 78 Female 7/20/2007 Physician Japan
Primary
Concomitant
Hypoglycaemic Coma Life Threatening 7/7/2007 78 Female 7/24/2007 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 6/20/2007 56 Male 7/30/2007 Physician Japan
Primary
Concomitant
Hypoglycaemic Coma Life Threatening 7/7/2007 78 Female 115 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 8/3/2007 Consumer Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 52 Male 8/7/2007 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 8/9/2007 Consumer Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 Male 8/10/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Myalgia Other Serious 3/13/2007 52 Male 8/14/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 Male 8/16/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 52 Male 8/21/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 Male 8/22/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Hospitalization 5/17/2007 Female 8/28/2007 Pharmacist Japan
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 5/17/2007 Female 9/17/2007 Pharmacist Japan
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 1/22/2007 63 Female 150 lb 9/14/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 5/17/2007 Female 9/20/2007 Pharmacist Japan
Primary
Concomitant
Cardiac Valve Disease Other Serious 7/28/2007 Female 9/24/2007 Physician Japan
Primary
Concomitant
Cardiac Valve Disease Hospitalization 7/28/2007 Female 10/16/2007 Physician Japan
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 5/17/2007 Female 10/24/2007 Pharmacist Japan
Primary
Concomitant
Wound Dehiscence Hospitalization 7/23/2007 74 Male 157 lb 10/31/2007 Physician Japan
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 4/11/2007 Male 165 lb 6/5/2008 Physician Japan
Primary
Secondary
Concomitant
Tremor Hospitalization 3/19/2008 72 Female 6/11/2008 Physician Japan
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 4/11/2007 Male 165 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/13/2008 67 Female 128 lb 7/24/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/7/2008 79 Female 10/9/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 9/7/2008 79 Female 10/13/2008 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 9/13/2008 Male 161 lb 12/8/2008 Physician Japan
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Hospitalization 1/27/2009 86 Female 2/3/2009 Pharmacist Japan
Primary
Concomitant
Viral Skin Infection Hospitalization 11/1/2008 Male 2/3/2009 Pharmacist Japan
Primary
Concomitant
Infection Other Serious 4/11/2007 Male 165 lb 3/4/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/26/2009 86 Female 99 lb 3/5/2009 Pharmacist Japan
Primary
Concomitant
Malaise Other Serious 11/4/2008 3/6/2009 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 11/1/2007 76 Male 95 lb 3/9/2009 Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 11/13/2008 Male 134 lb 3/11/2009 Physician
Primary
Concomitant
Visual Acuity Reduced Other Serious 11/13/2008 Male 134 lb 3/16/2009 Physician
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 4/9/2009 51 Male 4/21/2009 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 8/7/2006 Male 167 lb 4/24/2009 Japan
Primary
Concomitant
Acute Hepatic Failure Life Threatening 4/8/2009 51 Male 171 lb 4/28/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/12/2009 Male 137 lb 5/6/2009 Physician Japan
Primary
Secondary
Concomitant
Cellulitis Hospitalization 3/26/2009 72 5/29/2009 Physician Japan
Primary
Concomitant
Paralysis Hospitalization 4/16/2009 71 Female 6/5/2009 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Other Serious 6/9/2009 61 Male 152 lb 6/15/2009 Physician Japan
Primary
Secondary
Concomitant
Cellulitis Hospitalization 3/26/2009 72 6/23/2009 Physician Japan
Primary
Concomitant
Cellulitis Hospitalization 3/26/2009 72 7/2/2009 Physician Japan
Primary
Concomitant
Colitis Ischaemic Hospitalization 6/20/2009 Female 130 lb 7/8/2009 Physician Japan
Primary
Secondary
Concomitant
Colitis Ischaemic Hospitalization 6/20/2009 Female 130 lb 7/17/2009 Physician Japan
Primary
Secondary
Concomitant
Rectal Ulcer Haemorrhage Hospitalization 5/26/2009 Female 205 lb 7/22/2009 Pharmacist Japan
Primary
Concomitant
Pulmonary Fibrosis Other Serious 1/12/2009 85 7/27/2009 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/8/2009 Female 8/3/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/8/2009 Female 8/5/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 1/12/2009 84 8/19/2009 Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 2/12/2009 Female 73 lb 8/20/2009 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2009 Male 9/10/2009 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 4/28/2009 Male 359 lb 10/2/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2009 Male 10/6/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2009 Female 53 lb 10/9/2009 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 2/12/2009 Female 73 lb 10/13/2009 Other Health Professional Japan
Primary
Concomitant
Dysuria Disability 9/1/2009 Male 141 lb 11/4/2009 Pharmacist Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 Female 53 lb 11/5/2009 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 7/3/2009 77 Male 121 lb 11/5/2009 Physician Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 2/12/2009 Female 73 lb 11/6/2009 Other Health Professional Japan
Primary
Concomitant
Dysuria 9/1/2009 Male 141 lb 11/10/2009 Pharmacist Japan
Primary
Concomitant
Pneumonitis Hospitalization 9/30/2008 Male 119 lb 11/10/2009 Other Health Professional Japan
Primary
Concomitant
Ascites Hospitalization 11/3/2009 76 Female 115 lb 11/17/2009 Physician United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/23/2007 Male 110 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
Oesophageal Varices Haemorrhage Other Serious 8/15/2009 59 Male 139 lb 12/3/2009 Physician Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 2/12/2009 71 Female 73 lb 12/7/2009 Other Health Professional Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 2/12/2009 71 Female 73 lb 1/15/2010 Other Health Professional Japan
Primary
Concomitant
Death Death 12/9/2008 Female 2/8/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 2/12/2009 71 Female 73 lb 2/12/2010 Other Health Professional Japan
Primary
Concomitant
Dermatitis Bullous Hospitalization 4/26/2009 Female 126 lb 2/12/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/8/2008 Male 128 lb 2/16/2010 Physician Japan
Primary
Secondary
Concomitant
Adverse Event Hospitalization 2/28/2008 78 Female 2/16/2010 Physician Japan
Primary
Concomitant
Tonsillitis Hospitalization 9/5/2008 Female 2/23/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/4/2009 Male 196 lb 2/26/2010 Physician Japan
Primary
Concomitant
Constipation Hospitalization 3/13/2009 52 Male 2/23/2010 Japan
Primary
Concomitant
Pleural Effusion Hospitalization 2/2/2010 63 Male 117 lb 3/4/2010 Physician Japan
Primary
Concomitant
Pharyngeal Haemorrhage Other Serious 10/2/2009 59 Male 118 lb 3/12/2010 Physician Japan
Primary
Concomitant
Venous Thrombosis Hospitalization 1/1/2010 Female 110 lb 3/11/2010 Physician Japan
Primary
Concomitant
Death Death 12/9/2008 Female 3/23/2010 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 2/1/2010 Female 110 lb 3/18/2010 Physician Japan
Primary
Concomitant
Death Death 12/7/2009 82 Male 115 lb 4/9/2010 Physician Japan
Primary
Concomitant
Hypothyroidism Other Serious 7/29/2009 53 Female 88 lb 4/9/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 5/19/2009 72 Male 165 lb 4/12/2010 Physician Japan
Primary
Concomitant
Bradycardia Life Threatening 3/21/2010 68 Female 132 lb 4/14/2010 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/4/2009 59 Male 196 lb 4/15/2010 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 3/19/2010 66 Female 132 lb 5/24/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumothorax Life Threatening 2/17/2010 72 Male 6/1/2010 Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/25/2010 70 Female 6/23/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/19/2010 66 Female 132 lb 7/7/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 5/25/2010 70 Female 7/19/2010 Physician Japan
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 5/27/2010 88 Female 7/30/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/25/2010 70 Female 8/20/2010 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 1/1/2010 70 Female 9/7/2010 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 9/10/2010 66 Female 10/20/2010 Physician Japan
Primary
Secondary
Concomitant
Lip And/or Oral Cavity Cancer Hospitalization 8/27/2009 66 Female 10/27/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 9/20/2010 80 Female 10/28/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/20/2010 Female 10/28/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Rash Hospitalization 7/3/2009 77 Male 121 lb 11/5/2010 Physician Japan
Primary
Concomitant
Osteomyelitis Hospitalization 4/7/2010 61 Female 112 lb 11/9/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/30/2009 74 Female 112 lb 11/10/2010 Physician Japan
Primary
Concomitant
Vertigo Other Serious 5/1/2010 63 Female 104 lb 11/12/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 10/20/2010 11/17/2010 Other Health Professional Japan
Primary
Concomitant
X-ray Abnormal Other Serious 9/27/2010 76 Female 11/18/2010 Pharmacist Japan
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 9/8/2010 66 Male 113 lb 11/29/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 10/20/2010 11/30/2010 Physician Japan
Primary
Concomitant
Urticaria Life Threatening 10/10/2010 57 Female 128 lb 12/6/2010 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 4/16/2010 70 Male 101 lb 12/23/2010 Physician Japan
Primary
Concomitant
Osteomyelitis Hospitalization 4/7/2010 61 Female 112 lb 12/29/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 5/19/2009 71 Male 163 lb 12/29/2010 Physician Japan
Primary
Concomitant
Joint Swelling Other Serious 10/5/2009 68 Male 163 lb 1/4/2011 Physician Japan
Primary
Concomitant
Blood Urea Increased Hospitalization 6/16/2007 73 Male 148 lb 1/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 1/12/2010 85 Female 1/9/2011 Pharmacist Japan
Primary
Concomitant
Cellulitis Hospitalization 3/26/2009 72 Female 152 lb 1/20/2011 Physician Japan
Primary
Concomitant
Ileus Other Serious 4/20/2010 79 Male 158 lb 1/21/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 6/16/2007 73 Male 148 lb 1/25/2011 Japan
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 1/12/2010 85 Female 1/25/2011 Pharmacist Japan
Primary
Concomitant
Inflammation Hospitalization 12/14/2010 71 Male 1/26/2011 Physician Japan
Primary
Concomitant
Joint Swelling Hospitalization 10/5/2009 68 Male 163 lb 1/27/2011 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Life Threatening 8/14/2009 59 Male 138 lb 1/28/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 10/25/2010 61 Male 143 lb 1/28/2011 Physician Japan
Primary
Concomitant
Ileus Hospitalization 4/20/2010 79 Male 158 lb 2/3/2011 Physician Japan
Primary
Concomitant
Biloma Hospitalization 3/1/2010 87 Male 106 lb 2/15/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 10/18/2010 80 Male 3/4/2011 Physician Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 12/14/2010 71 Male 3/7/2011 Physician Japan
Primary
Secondary
Concomitant
Nausea Other Serious 11/2/2010 76 Female 3/8/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Infection Other Serious 12/14/2010 71 Male 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Dizziness Other Serious 2/21/2011 69 Male 3/9/2011 Pharmacist Japan
Primary
Concomitant
Inflammation Hospitalization 12/14/2010 71 Male 3/10/2011 Physician Japan
Primary
Secondary
Concomitant
Biloma Hospitalization 3/1/2010 87 Male 106 lb 3/11/2011 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 8/14/2009 59 Male 139 lb 3/15/2011 Physician Japan
Primary
Secondary
Concomitant
Off Label Use Life Threatening 9/21/2010 68 Male 3/16/2011 Physician Japan
Primary
Concomitant
Sepsis Other Serious 12/14/2010 71 Male 3/18/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Other Serious 11/2/2010 76 Female 3/21/2011 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 12/1/2010 60 Male 3/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/28/2011 77 Male 3/31/2011 Physician Japan
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 3/17/2011 72 Female 104 lb 3/31/2011 Physician Japan
Primary
Concomitant
Pneumonia Viral Other Serious 12/14/2010 71 Male 4/27/2011 Physician Japan
Primary
Secondary
Concomitant
Retinal Pigment Epithelial Tear Disability 5/8/2009 80 Male 5/3/2011 Consumer Switzerland
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 1/11/2011 71 Male 5/6/2011 Physician Japan
Primary
Secondary
Concomitant
Colitis Ischaemic Life Threatening 3/7/2011 79 Male 165 lb 5/17/2011 Physician Japan
Primary
Concomitant
Hepatorenal Failure Hospitalization 7/3/2009 76 Male 119 lb 6/3/2011 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 4/16/2010 70 Male 101 lb 6/3/2011 Physician Japan
Primary
Concomitant

Drug Data