Amlodipine combined with Isosorbide Mononitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Hospitalization 1/1/2000 83 Female 99 lb 1/25/2006 United Kingdom
Primary
Concomitant
Renal Failure Chronic Life Threatening 12/11/2005 84 Female 88 lb 1/23/2006 Physician Japan
Primary
Concomitant
Hyponatraemia Other Serious 12/21/2005 70 Male 1/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Hospitalization 6/16/2005 67 Female 1/12/2006 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Nitritoid Crisis Other Serious 8/22/2002 63 Male 2/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Renal Failure Chronic Life Threatening 12/11/2005 84 Female 88 lb 2/13/2006 Physician Japan
Primary
Concomitant
Syncope Vasovagal Other Serious 8/22/2002 63 Male 2/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Vasovagal Other Serious 8/22/2002 63 Male 3/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Odynophagia Hospitalization 1/15/2006 71 Male 3/10/2006 Physician Japan
Primary
Secondary
Oedema Peripheral Disability 2/16/2006 67 Female 3/3/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Angioneurotic Oedema Hospitalization 1/15/2006 71 Male 3/17/2006 Physician Japan
Primary
Secondary
White Blood Cell Count Increased Hospitalization 1/15/2006 71 Male 4/3/2006 Physician Japan
Primary
Secondary
Tibia Fracture Hospitalization 1/20/2006 56 Male 194 lb 4/24/2006 Physician United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/1/2004 60 Male 4/25/2006 Brazil
Primary
Concomitant
Pharyngeal Oedema Hospitalization 12/29/2005 66 Male 4/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Burning Sensation Hospitalization 11/1/2005 77 Female 134 lb 5/3/2006 Physician United Kingdom
Primary
Concomitant
Therapy Non-responder Required Intervention 78 Female 5/16/2006 Germany
Primary
Secondary
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 6/2/2006 Consumer United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 11/19/2005 78 Male 196 lb 6/13/2006 United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 10/4/2005 74 Female 142 lb 6/15/2006 Physician Finland
Primary
Secondary
Concomitant
Skin Burning Sensation Hospitalization 11/1/2005 77 Female 134 lb 6/22/2006 Physician United Kingdom
Primary
Concomitant
Pericardial Haemorrhage Death 2/8/2006 Female 146 lb 7/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 7/17/2006 Other Health Professional Japan
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 7/26/2006 Other Health Professional Japan
Primary
Concomitant
Hypertension Hospitalization 4/6/2006 66 Male 7/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Other Serious 1/1/2000 73 Male 217 lb 7/19/2006 Consumer United Kingdom
Primary
Concomitant
Skin Lesion 1/1/2005 Male 161 lb 8/4/2006 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 6/12/2006 55 Female 8/9/2006 United States
Primary
Concomitant
Metastasis Other Serious 6/20/2006 75 Female 8/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 3/3/2006 78 Male 141 lb 8/11/2006 Other Health Professional Japan
Primary
Concomitant
Hypersensitivity Hospitalization 3/31/2006 66 Male 8/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Intracranial Aneurysm Hospitalization 6/21/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Rash Required Intervention 5/13/2006 47 Female 242 lb 5/23/2006 Pharmacist United States
Primary
Concomitant
Thrombophlebitis Required Intervention 8/24/2006 57 Male 133 lb 9/13/2006 Physician Australia
Primary
Concomitant
Skin Oedema Hospitalization 76 Male 9/21/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/27/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 1/1/2000 65 Male 10/31/2006 India
Primary
Secondary
Concomitant
Tibia Fracture Hospitalization 1/20/2006 56 Male 194 lb 11/9/2006 Physician United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 12/4/2006 Female 176 lb 12/5/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 11/5/2006 80 Female 132 lb 12/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Oedema Hospitalization 76 Male 12/14/2006 Other Health Professional United States
Primary
Concomitant
Pericardial Haemorrhage Death 2/8/2006 Female 146 lb 1/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cyst Hospitalization 4/3/2005 Male 212 lb 1/19/2007 Consumer United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Disability 2/16/2006 67 Female 2/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Injury Disability 9/1/2006 83 Female 3/1/2007
Primary
Concomitant
Renal Failure Disability 9/1/2006 83 Female 2/26/2007 United Kingdom
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 12/1/2006 84 Female 185 lb 3/16/2007 Physician United Kingdom
Primary
Concomitant
Hypotension Hospitalization 2/13/2007 84 Male 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Hospitalization 2/13/2007 84 Male 3/19/2007 United Kingdom
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 12/1/2006 84 Female 185 lb 3/27/2007 Physician United Kingdom
Primary
Concomitant
Myositis Disability 12/1/2006 81 Female 4/6/2007 Consumer United Kingdom
Primary
Concomitant
Syncope Other Serious 3/13/2007 80 Male 4/13/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Linear Iga Disease Life Threatening 1/23/2007 79 Female 110 lb 4/30/2007 Consumer United Kingdom
Primary
Concomitant
Hypercalcaemia Hospitalization 8/15/2006 Male 170 lb 5/3/2007 United Kingdom
Primary
Concomitant
Linear Iga Disease Life Threatening 1/23/2007 79 Female 110 lb 4/28/2007 United Kingdom
Primary
Concomitant
Tachycardia Other Serious 82 Female 6/14/2007 Other Health Professional United States
Primary
Secondary
Urinary Tract Infection Life Threatening 2/1/2007 Female 6/15/2007 Physician Norway
Primary
Concomitant
Metastasis Other Serious 6/20/2006 75 Female 6/18/2007 Pharmacist United Kingdom
Primary
Concomitant
Lobar Pneumonia Disability 82 Female 124 lb 6/14/2007 United States
Primary
Secondary
Nephrolithiasis Hospitalization 6/14/2007 46 Male 210 lb 6/27/2007 Consumer United Kingdom
Primary
Concomitant
Vasodilatation Hospitalization 78 Female 7/27/2007 Germany
Primary
Secondary
Somnolence Life Threatening 4/18/2007 56 Male 8/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Life Threatening 4/18/2007 56 Male 8/1/2007 United Kingdom
Primary
Secondary
Concomitant
Vasodilatation Hospitalization 78 Female 7/27/2007 Germany
Primary
Secondary
Somnolence Life Threatening 4/18/2007 56 Male 8/1/2007 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 73 Male 8/8/2007 Israel
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 7/2/2007 82 Female 9/7/2007 United Kingdom
Primary
Concomitant
Muscle Spasms Hospitalization 8/15/2007 83 Female 10/12/2007 Consumer United Kingdom
Primary
Concomitant
Head Injury Hospitalization 6/17/2007 Female 120 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 5/1/2007 68 Male 198 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Head Injury Hospitalization 6/17/2007 Female 120 lb 11/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 11/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Troponin Increased Life Threatening 10/20/2007 Male 11/20/2007 United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Life Threatening 10/20/2007 Male 11/20/2007 United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 8/15/2007 83 Female 11/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Life Threatening 10/20/2007 67 Male 154 lb 11/26/2007 United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 2/27/2007 62 Male 11/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 10/20/2007 67 Male 154 lb 11/26/2007 United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 10/20/2007 67 Male 11/29/2007 United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 10/20/2007 67 Male 11/26/2007 United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Life Threatening 10/20/2007 67 Male 154 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 67 Male 154 lb 11/30/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Endotracheal Intubation Complication Life Threatening 10/3/2007 Female 165 lb 12/5/2007 Pharmacist United States
Primary
Concomitant
Syncope Vasovagal Disability 5/10/2001 63 Male 12/14/2007 United Kingdom
Primary
Secondary
Concomitant
Nitritoid Reaction Other Serious 8/22/2002 63 Male 12/13/2007 United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 9/7/2007 Female 176 lb 12/20/2007 Greece
Primary
Concomitant
Rhabdomyolysis Other Serious 42 Male 12/20/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 10/20/2007 67 Male 12/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 10/20/2007 67 Male 154 lb 12/20/2007
Primary
Secondary
Concomitant
Rectal Cancer Hospitalization 9/7/2007 Female 176 lb 12/28/2007 Greece
Primary
Concomitant
Rectal Cancer Hospitalization 9/7/2007 Female 176 lb 1/10/2008 Greece
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 10/20/2007 67 Male 1/4/2008 United Kingdom
Primary
Secondary
Concomitant
Colorectal Cancer Hospitalization 9/7/2007 Female 176 lb 1/14/2008 Greece
Primary
Concomitant
Rheumatoid Arthritis Disability 2/16/2006 67 Female 1/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 8/1/2002 68 Male 201 lb 2/1/2008 United States
Primary
Concomitant
Weight Decreased Life Threatening 2/14/2007 Female 2/1/2008 Physician Norway
Primary
Concomitant
Syncope Vasovagal Disability 5/10/2001 63 Male 12/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Mass Hospitalization 2/15/2008 Male 228 lb 3/18/2008 United States
Primary
Secondary
Concomitant
Colon Cancer Hospitalization 12/5/2007 Male 203 lb 4/4/2008 Physician Netherlands
Primary
Concomitant
Swollen Tongue Life Threatening 10/3/2007 Female 155 lb 4/8/2008 Pharmacist United States
Primary
Secondary
Concomitant
Colon Cancer Hospitalization 12/5/2007 Male 203 lb 4/17/2008 Physician Netherlands
Primary
Concomitant
Weight Decreased Hospitalization 3/19/2008 85 Male 146 lb 4/17/2008 Pharmacist United States
Primary
Concomitant
Colon Cancer Hospitalization 12/5/2007 Male 203 lb 4/23/2008 Physician Netherlands
Primary
Concomitant
Cardio-respiratory Arrest Death 12/15/2003 Male 231 lb 5/13/2008 Poland
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 5/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 88 Male 5/27/2008 Other Health Professional France
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 88 Male 5/22/2008 United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 5/15/2008 Female 140 lb 5/30/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/28/2008 89 Male 5/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/28/2008 89 Male 5/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 60 Male 5/30/2008 Physician Sweden
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 88 Male 6/9/2008
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2/28/2008 89 Male 6/10/2008
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/7/2008 Female 207 lb 6/27/2008 Consumer United Kingdom
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 Male 6/27/2008 Netherlands
Primary
Concomitant
Hypomagnesaemia Hospitalization 81 Male 7/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 81 Male 7/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 81 Male 8/3/2008 United Kingdom
Primary
Concomitant
No Adverse Event 2/15/2008 Male 228 lb 8/11/2008 United States
Primary
Concomitant
Oedema Peripheral 7/2/2008 69 Male 8/4/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/28/2008 89 Male 6/10/2008
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/1998 Male 8/15/2008 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 81 Male 8/8/2008 United Kingdom
Primary
Concomitant
Jaundice Cholestatic Other Serious 8/11/2008 Female 9/15/2008 Other Health Professional Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 81 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 81 Male 9/29/2008
Primary
Secondary
Concomitant
Death Death 3/9/2008 77 Male 104 lb 10/23/2008 Physician Greece
Primary
Concomitant
Febrile Neutropenia Hospitalization 9/25/2008 Female 10/24/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 81 Male 10/29/2008 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 81 Male 10/21/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 81 Male 10/29/2008 United Kingdom
Primary
Secondary
Concomitant
Septic Shock Death 3/9/2008 77 Male 104 lb 11/6/2008 Physician Greece
Primary
Concomitant
Pain In Extremity Hospitalization 10/21/2008 82 Female 216 lb 11/6/2008 Physician Sweden
Primary
Concomitant
Urinary Tract Infection Required Intervention 81 Male 11/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 81 Male 11/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/25/2008 Female 11/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sneezing 10/1/2008 Male 245 lb 11/26/2008 Pharmacist United States
Primary
Concomitant
Product Quality Issue Other Serious 7/1/2007 56 Male 190 lb 11/25/2008 Consumer United States
Primary
Concomitant
Septic Shock Death 11/9/2007 77 Male 104 lb 12/9/2008 Physician Greece
Primary
Concomitant
Product Quality Issue Hospitalization 6/1/2008 76 Female 125 lb 12/10/2008 Consumer United States
Primary
Concomitant
Flatulence 4/1/2008 78 Female 155 lb 12/17/2008 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/1998 78 Male 137 lb 1/14/2009 Consumer United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 4/1/2008 56 Female 1/15/2009 Consumer United States
Primary
Concomitant
Vertigo Hospitalization 11/1/2008 55 Female 112 lb 1/23/2009 Consumer United States
Primary
Concomitant
Pericarditis Hospitalization 3/2/2007 Male 152 lb 2/2/2009 Physician Poland
Primary
Concomitant
Syncope Hospitalization 1/23/2009 79 Male 2/2/2009 Other Health Professional United States
Primary
Secondary
Hyperuricaemia Hospitalization 10/21/2008 82 Female 216 lb 1/29/2009 Physician Sweden
Primary
Concomitant
Jaundice Cholestatic Other Serious 8/11/2008 84 Female 2/10/2009 Other Health Professional Japan
Primary
Concomitant

Drug Data