Amlodipine combined with Isosorbide Dinitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypertensive Crisis Hospitalization 12/30/2005 44 Female 194 lb 3/24/2006 Physician Germany
Primary
Concomitant
Pancytopenia Other Serious 3/7/2003 Female 126 lb 4/3/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 60 Male 207 lb 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 68 Male 8/16/2006 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 8/19/2006 28 Female 137 lb 9/15/2006 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/19/2006 28 Female 137 lb 9/22/2006 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 8/19/2006 28 Female 115 lb 9/25/2006 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 8/1/2006 79 Female 112 lb 10/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Bronchopneumonia Life Threatening 2/4/2006 57 Female 11/2/2006 Physician Germany
Primary
Concomitant
Renal Failure Chronic Hospitalization 4/26/2005 78 Female 154 lb 12/11/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Required Intervention 5/16/2006 76 Female 12/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Scotoma Other Serious 1/1/2005 68 Male 12/15/2006 United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 8/1/2006 79 Female 112 lb 1/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Pneumonia Hospitalization 8/19/2006 28 Female 115 lb 3/5/2007 Consumer United States
Primary
Concomitant
Muscle Spasms Other Serious 1/1/2007 Male 364 lb 6/18/2007 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 3/16/2006 Male 6/25/2007 United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 3/1/2007 Male 214 lb 7/18/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 5/1/2007 70 Male 154 lb 7/13/2007 Physician Japan
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 3/1/2007 Male 214 lb 7/23/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/3/2007 74 Female 132 lb 8/22/2007 Consumer Chile
Primary
Concomitant
Chest Pain Life Threatening 9/7/2007 54 Male 252 lb 10/5/2007 Physician Russian Federation
Primary
Concomitant
Dilatation Ventricular Life Threatening 9/7/2007 54 Male 252 lb 10/23/2007 Physician Russian Federation
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/1/2007 70 Male 154 lb 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 10/1/2007 69 Female 11/9/2007 Consumer United Kingdom
Primary
Concomitant
Underdose 1/1/2004 Male 241 lb 12/15/2007 Consumer United States
Primary
Concomitant
Lung Disorder Other Serious 9/1/2007 Male 235 lb 12/18/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint 8/4/2007 83 Female 2/6/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 65 Male 2/26/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 65 Male 3/4/2008 Other Health Professional United States
Primary
Concomitant
Accidental Exposure 1/27/2008 Female 110 lb 3/15/2008 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 6/27/2007 Female 326 lb 3/31/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 10/1/2007 59 Female 249 lb 4/11/2008 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/27/2008 Female 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nocturia Other Serious 8/3/2007 Female 4/14/2008 Physician United States
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 4/12/2008 Male 5/2/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization Male 138 lb 5/2/2008 Physician United States
Primary
Concomitant
Ischaemia Other Serious 4/24/2008 Female 153 lb 4/30/2008 Other Health Professional United States
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 4/12/2008 Male 5/8/2008 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2006 74 Male 5/17/2008 Consumer
Primary
Concomitant
Thrombocytopenia Hospitalization 10/12/2007 82 Male 192 lb 5/22/2008 Physician Germany
Primary
Concomitant
Hot Flush Other Serious 6/18/2008 83 Male 161 lb 6/26/2008 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2008 Male 6/30/2008 Consumer United States
Primary
Concomitant
Dilatation Ventricular Life Threatening 9/7/2007 Male 252 lb 7/21/2008 Physician Russian Federation
Primary
Concomitant
Tremor 11/12/2007 Male 175 lb 7/25/2008 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 9/1/2006 80 Female 8/14/2008 Physician Canada
Primary
Secondary
Concomitant
Flushing 6/1/2008 Male 223 lb 8/27/2008 United States
Primary
Concomitant
Heart Rate Decreased Other Serious 80 Female 8/26/2008 Pharmacist Denmark
Primary
Concomitant
Pruritus 7/1/2008 Female 210 lb 8/29/2008 United States
Primary
Concomitant
Metabolic Disorder Hospitalization 80 Female 8/21/2008 Consumer Canada
Primary
Secondary
Concomitant
Jaundice Cholestatic Other Serious 84 Female 9/4/2008 Other Health Professional Japan
Primary
Concomitant
Jaundice Cholestatic Other Serious 84 Female 9/4/2008 Other Health Professional Japan
Primary
Concomitant
Back Pain Other Serious 7/5/2008 10/13/2008 Canada
Primary
Concomitant
Fall Other Serious 9/1/2006 80 Female 12/1/2008
Primary
Secondary
Nephrogenic Systemic Fibrosis Other Serious 60 Female 12/5/2008 Physician Germany
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 67 Male 12/12/2008 Other Health Professional Spain
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2008 80 Female 215 lb 11/19/2008 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization Male 12/24/2008 Physician Bulgaria
Primary
Concomitant
Lung Disorder Death 9/29/2008 50 Male 1/6/2009 Consumer United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 60 Female 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Skin Burning Sensation 1/1/2004 Female 192 lb 1/15/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/9/2008 Male 1/19/2009 Lawyer United States
Primary
Concomitant
Medication Error Death 89 Female 1/14/2009 Physician United States
Primary
Secondary
Dizziness Hospitalization 5/24/2008 75 Male 1/21/2009 Consumer Germany
Primary
Concomitant
Syncope Hospitalization 6/12/2008 84 Female 1/22/2009 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 2/9/2008 82 Male 2/19/2009 Lawyer United States
Primary
Concomitant
Heart Rate Decreased Hospitalization 80 Female 3/4/2009 Canada
Primary
Concomitant
Pericardial Effusion Hospitalization 3/2/2009 Male 120 lb 3/13/2009 Physician India
Primary
Concomitant
Metastases To Bone Other Serious 2/22/2007 76 Male 5/1/2009 Japan
Primary
Concomitant
Potentiating Drug Interaction Other Serious 1/1/2009 64 Female 5/22/2009 Consumer United States
Primary
Concomitant
Mouth Haemorrhage Hospitalization 4/15/2009 Female 119 lb 6/17/2009 Physician Japan
Primary
Concomitant
Interacting
Urinary Tract Infection Enterococcal Other Serious 5/2/2003 Male 6/25/2009 Physician Germany
Primary
Secondary
Concomitant
Periorbital Oedema Other Serious 7/1/2008 6/30/2009 Other Health Professional Malaysia
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 4/15/2009 Female 119 lb 7/6/2009 Physician Japan
Primary
Concomitant
Interacting
Ventricular Extrasystoles Hospitalization 6/11/2009 85 Male 6/26/2009 Denmark
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/23/2005 Male 7/7/2009 Consumer Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/1/2007 82 Male 7/16/2009 Physician United States
Primary
Concomitant
Vomiting Death 81 Female 7/14/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 7/9/2009 81 Female 210 lb 7/31/2009 Consumer United States
Primary
Concomitant
Flushing 6/1/2008 Male 223 lb 8/21/2009 United States
Primary
Concomitant
Pruritus 1/1/2009 Male 8/22/2009 United States
Primary
Concomitant
Rash Male 8/22/2009 United States
Primary
Concomitant
Vomiting 2/1/2009 Male 8/22/2009 Consumer United States
Primary
Concomitant
Blood Glucose Increased 5/15/2009 Male 247 lb 8/22/2009 United States
Primary
Concomitant
Flushing 10/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Flushing Female 186 lb 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation 7/16/2009 Male 225 lb 8/23/2009 United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/19/2009 Female 245 lb 8/27/2009 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 52 Female 350 lb 9/1/2009 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 8/7/2009 49 Female 9/18/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 8/7/2009 49 Female 10/6/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 67 Male 10/16/2009 Other Health Professional Spain
Primary
Concomitant
Vomiting Other Serious 10/2/2009 80 Male 128 lb 10/26/2009 Physician Singapore
Primary
Secondary
Concomitant
Viral Rash Other Serious 8/24/2009 71 Female 10/23/2009 France
Primary
Secondary
Concomitant
Vomiting Other Serious 10/2/2009 80 Male 128 lb 10/29/2009 Physician Singapore
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 9/20/2009 Male 300 lb 10/20/2009 Consumer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 7/14/2009 75 Male 181 lb 10/30/2009 Japan
Primary
Concomitant
Vomiting Other Serious 10/2/2009 80 Male 128 lb 11/13/2009 Physician Singapore
Primary
Secondary
Concomitant
Vomiting Other Serious 10/2/2009 79 Male 11/13/2009 Other Health Professional Singapore
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 1/25/2010 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 1/27/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/27/2009 Female 179 lb 2/1/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/12/2010 92 Female 175 lb 2/19/2010 Physician Germany
Primary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 2/23/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/26/2010 Physician Argentina
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/29/2010 Physician Argentina
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 81 Female 4/9/2010 Physician Argentina
Primary
Concomitant
Vision Blurred Other Serious 3/17/2010 79 Female 161 lb 4/12/2010 Other Health Professional United States
Primary
Concomitant
Restlessness Hospitalization 1/1/2010 66 Female 4/14/2010 Physician Germany
Primary
Concomitant
Vomiting Other Serious 1/26/2008 53 Male 5/24/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 10/2/2009 80 Male 128 lb 6/14/2010 Physician Singapore
Primary
Secondary
Concomitant
Rash Hospitalization 3/17/2010 83 Male 6/24/2010 Consumer France
Primary
Secondary
Concomitant
Vomiting Other Serious 10/2/2009 79 Male 6/18/2010 Other Health Professional Singapore
Primary
Secondary
Concomitant
Dizziness Hospitalization 75 Male 7/22/2010 Consumer Germany
Primary
Concomitant
Vomiting Other Serious 1/1/2008 53 Male 293 lb 7/28/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 10/2/2009 80 Male 128 lb 8/4/2010 Physician Singapore
Primary
Secondary
Concomitant
Wheezing Other Serious 10/2/2009 79 Male 8/9/2010 Physician Singapore
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 51 Male 8/25/2010 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Other Serious Female 9/15/2010 Physician Germany
Primary
Secondary
Pain Other Serious 4/1/2010 72 Female 108 lb 10/11/2010 Physician United States
Primary
Concomitant
Petechiae Other Serious 9/6/2010 57 Male 143 lb 9/10/2010 Pharmacist United States
Primary
Concomitant
Visual Impairment Other Serious 4/10/2009 55 Female 185 lb 10/14/2010 Consumer Brazil
Primary
Concomitant
Visual Impairment Other Serious 4/10/2009 55 Female 185 lb 10/15/2010 Consumer Brazil
Primary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 10/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertensive Crisis Hospitalization 69 Male 198 lb 10/22/2010 Physician Germany
Primary
Concomitant
Dyspnoea Hospitalization 82 Female 11/1/2010 Consumer United States
Primary
Concomitant
Vertebral Artery Stenosis Hospitalization 9/13/2010 78 Male 188 lb 11/2/2010 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 2/10/2004 60 Female 141 lb 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Oral Mucosal Exfoliation Female 11/2/2010 United States
Primary
Concomitant
Drug Ineffective Hospitalization Male 198 lb 11/3/2010 Physician Germany
Primary
Concomitant
Respiratory Arrest Hospitalization 68 Male 303 lb 11/4/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 3/1/2009 70 Female 115 lb 11/12/2010 Other Health Professional United States
Primary
Concomitant
Product Quality Issue Other Serious 86 Female 11/18/2010 Consumer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 8/1/2010 75 Male 12/1/2010 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 1/1/2007 36 Female 12/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 8/1/2010 75 Male 12/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 8/1/2010 75 Male 12/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 8/1/2010 75 Male 12/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 8/1/2010 75 Male 12/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 8/1/2010 75 Male 12/2/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 86 Female 12/17/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/1/2010 75 Male 12/9/2010 United Kingdom
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 12/17/2010 Female 12/27/2010 Physician Philippines
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 75 Male 110 lb 12/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 12/1/2010 77 Male 1/4/2011 Consumer
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 75 Male 110 lb 12/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 12/1/2010 76 Female 1/6/2011 Consumer United States
Primary
Concomitant
Choking Other Serious 86 Female 1/6/2011 Consumer United States
Primary
Concomitant
Rash 74 Female 1/10/2011 Consumer United States
Primary
Concomitant
Choking Other Serious 86 Female 1/12/2011 Consumer United States
Primary
Concomitant
Nail Discolouration Other Serious 86 Female 1/14/2011 Consumer United States
Primary
Concomitant

Drug Data