Amlodipine Besylate combined with Metoprolol Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Life Threatening 4/22/2005 Male 254 lb 2/13/2006 United States
Primary
Concomitant
Pain In Jaw Other Serious 12/1/2005 37 Female 160 lb 2/20/2006 Consumer United States
Primary
Secondary
Concomitant
Pruritus Generalised Other Serious 12/1/2005 37 Female 160 lb 3/8/2006 Consumer United States
Primary
Secondary
Concomitant
Contusion Hospitalization 3/17/2004 53 Female 190 lb 12/27/2005 Consumer United States
Primary
Concomitant
Pruritus Generalised Other Serious 12/1/2005 37 Female 160 lb 4/5/2006 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Bacterial Other Serious 4/13/2006 69 Female 165 lb 5/5/2006 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 12/28/2005 76 Male 200 lb 2/2/2006 Physician United States
Primary
Concomitant
Gastroenteritis Hospitalization 10/9/2005 55 Female 5/30/2006 Physician Germany
Primary
Secondary
Concomitant
Cardiomyopathy Life Threatening 4/22/2005 Male 254 lb 6/16/2006 United States
Primary
Concomitant
Incisional Hernia Hospitalization 1/10/2006 Male 148 lb 8/11/2006 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 7/8/2006 91 Female 109 lb 8/1/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 7/8/2006 91 Female 109 lb 8/1/2006 Physician United States
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 10/9/2005 55 Female 10/6/2006 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/15/2005 Male 10/12/2006 Other Health Professional France
Primary
Concomitant
Oesophageal Ulcer Hospitalization 12/10/2005 82 Female 170 lb 11/22/2006 Consumer United States
Primary
Secondary
Concomitant
Melaena Other Serious 3/15/1999 72 Male 169 lb 11/17/2006 Consumer United States
Primary
Secondary
Concomitant
Myalgia Other Serious 7/12/2006 58 Male 198 lb 8/15/2006 Other Health Professional United States
Primary
Concomitant
Oedema Due To Cardiac Disease Hospitalization 80 Female 11/24/2006 Germany
Primary
Secondary
Concomitant
Cardiomegaly Other Serious 4/24/2006 Female 160 lb 12/14/2006 Consumer Canada
Primary
Concomitant
Heart Rate Irregular Hospitalization 12/1/2004 65 Female 12/12/2006 Consumer United States
Primary
Concomitant
Insomnia 7/1/2006 69 Male 179 lb 10/11/2006 Consumer United States
Primary
Concomitant
Somnolence 7/10/2006 79 Female 156 lb 10/11/2006 Consumer United States
Primary
Concomitant
Hallucination 5/1/2006 76 Female 10/11/2006 Consumer United States
Primary
Concomitant
Death Death Male 262 lb 1/19/2007 United States
Primary
Concomitant
Vertigo Other Serious 4/1/2006 Female 1/16/2007 United States
Primary
Concomitant
Spinal Fracture Life Threatening 3/1/2005 Female 154 lb 1/25/2007 Belgium
Primary
Concomitant
Death Death 1/4/2007 Male 226 lb 3/9/2007 United States
Primary
Concomitant
Death Death 1/4/2007 Male 226 lb 3/19/2007 United States
Primary
Concomitant
Dyspnoea Other Serious Male 206 lb 3/22/2007 Consumer Canada
Primary
Concomitant
Dysgeusia 11/1/2006 85 Female 140 lb 1/12/2007 Consumer United States
Primary
Concomitant
Insomnia 9/28/2006 55 Male 245 lb 1/12/2007 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious Male 206 lb 4/20/2007 Physician Canada
Primary
Concomitant
Lower Limb Fracture Other Serious 12/1/2006 Female 136 lb 5/3/2007 Consumer United States
Primary
Concomitant
Headache Hospitalization 1/1/2007 79 Female 5/8/2007 Consumer Canada
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 9/5/2005 12/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 6/9/2006 76 Male 157 lb 12/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Contusion Hospitalization 8/7/2006 89 Female 123 lb 12/13/2006 Consumer United States
Primary
Concomitant
Vitreous Floaters Required Intervention 1/1/2005 66 Female 254 lb 6/13/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 10/1/2006 58 Female 220 lb 6/13/2007 Other Health Professional United States
Primary
Concomitant
Spinal Fracture Life Threatening 3/1/2005 Female 154 lb 7/13/2007 Belgium
Primary
Concomitant
Somnolence 1/1/2005 68 Male 230 lb 7/10/2007 Consumer United States
Primary
Secondary
Concomitant
Amnesia 4/6/2007 65 Male 280 lb 7/10/2007 Consumer United States
Primary
Concomitant
Nausea Hospitalization 6/15/2007 89 Female 8/30/2007 Physician Belgium
Primary
Concomitant
Renal Failure Acute Hospitalization 10/10/2006 Male 9/4/2007 Germany
Primary
Concomitant
Drug Toxicity Hospitalization 1/1/1998 59 Male 8/7/2007 Consumer United States
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 9/1/2005 Female 136 lb 11/9/2007 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 9/1/2005 Female 136 lb 11/14/2007 Physician United States
Primary
Concomitant
Weight Decreased 2/1/2007 64 Male 230 lb 11/16/2007 Physician United States
Primary
Concomitant
Accidental Exposure 2/15/2007 Female 209 lb 3/14/2008 Consumer United States
Primary
Concomitant
Hypertension Female 4/18/2008 Consumer United States
Primary
Secondary
Myocardial Infarction Other Serious 1/1/2004 Male 6/27/2008 Consumer
Primary
Concomitant
Throat Tightness Other Serious 1/1/2008 69 Female 8/4/2008 United States
Primary
Concomitant
Skin Exfoliation Other Serious 69 Female 187 lb 8/26/2008 Consumer United States
Primary
Concomitant
Angina Pectoris Hospitalization 4/14/2008 62 Male 9/2/2008 Physician Russian Federation
Primary
Concomitant
Angina Pectoris Hospitalization 4/14/2008 62 Male 9/8/2008 Physician Russian Federation
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/12/2008 50 Female 245 lb 10/10/2008 Physician Germany
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/12/2008 50 Female 245 lb 10/16/2008 Physician Germany
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/12/2008 50 Female 245 lb 10/20/2008 Physician Germany
Primary
Concomitant
Memory Impairment Required Intervention 3/1/2008 52 Female 158 lb 10/16/2008 Consumer United States
Primary
Concomitant
Memory Impairment Other Serious 3/1/2008 52 Female 185 lb 11/5/2008 Other Health Professional United States
Primary
Concomitant
Allergic Granulomatous Angiitis Life Threatening 9/26/2008 72 Female 11/17/2008 Other Health Professional Finland
Primary
Concomitant
Pancreatitis Acute Life Threatening 9/9/2008 50 Female 218 lb 11/24/2008 Physician Germany
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/12/2008 Female 11/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Life Threatening 9/9/2008 50 Female 218 lb 12/2/2008 Physician Germany
Primary
Concomitant
Pancreatitis Acute Life Threatening 9/1/2008 50 Female 245 lb 12/12/2008 Physician Germany
Primary
Concomitant
Respiratory Failure Hospitalization 7/2/2008 51 Male 1/20/2009 Germany
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 65 Male 185 lb 4/6/2009 Consumer United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 65 Male 185 lb 4/8/2009 Consumer United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/12/2008 Female 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Temporal Arteritis Other Serious 1/1/2009 Female 102 lb 5/30/2009 Consumer United States
Primary
Concomitant
Drug Ineffective 2/1/2009 Male 130 lb 6/12/2009 Consumer United States
Primary
Concomitant
Post Herpetic Neuralgia Life Threatening 5/10/2004 Female 6/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 11/26/2004 Male 6/25/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Tongue Oedema Hospitalization 50 Female 7/16/2009 Pharmacist United States
Primary
Concomitant
Incorrect Dose Administered 2/15/2007 Female 209 lb 9/11/2009 Consumer United States
Primary
Concomitant
Rash Other Serious 82 Female 9/16/2009 United States
Primary
Concomitant
Vomiting Hospitalization 63 Male 180 lb 9/25/2009 United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization Female 10/9/2009 Consumer United States
Primary
Concomitant
Lung Disorder Life Threatening 4/1/2009 Male 10/6/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/5/2009 Male 10/26/2009 Physician United States
Primary
Secondary
Concomitant
Temporal Arteritis Other Serious 1/1/2009 Female 102 lb 12/1/2009 Consumer United States
Primary
Concomitant
Gastric Dilatation Hospitalization 12/31/2009 Female 132 lb 1/11/2010 Physician China
Primary
Concomitant
Gastric Dilatation Hospitalization 12/31/2009 Female 132 lb 2/2/2010 Physician China
Primary
Concomitant
Renal Failure Chronic Other Serious 2/1/2004 63 Female 137 lb 4/23/2010 Physician Germany
Primary
Concomitant
Ventricular Fibrillation Hospitalization 17 Female 5/12/2010 United States
Primary
Secondary
Hernia Other Serious 1/1/2009 53 Female 112 lb 5/27/2010 Consumer United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 17 Female 5/24/2010 Poland
Primary
Secondary
Hyperglycaemia Hospitalization 5/1/2010 80 Male 6/4/2010 Physician Germany
Primary
Concomitant
Hyperkalaemia Life Threatening 12/1/2008 79 Female 152 lb 6/14/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hernia Other Serious 1/1/2009 53 Female 112 lb 6/17/2010 Consumer United States
Primary
Concomitant
Hyperglycaemia Other Serious 5/1/2010 80 Female 176 lb 6/23/2010 Physician Germany
Primary
Concomitant
Protein Urine Present Other Serious 5/1/2010 80 Female 176 lb 6/25/2010 Physician Germany
Primary
Concomitant
Vision Blurred Other Serious 1/4/2008 72 Male 7/13/2010 Lawyer United States
Primary
Secondary
Concomitant
Death Death 7/19/2010 67 Male 165 lb 7/22/2010 Consumer United States
Primary
Concomitant
Sepsis Death 8/11/2010 77 Male 9/8/2010 Consumer France
Primary
Secondary
Vision Blurred Other Serious 1/1/2008 72 Male 214 lb 9/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 2/1/2010 79 Female 9/22/2010 Physician Norway
Primary
Concomitant
Interacting
Sepsis Death 8/11/2010 77 Male 9/23/2010 Consumer France
Primary
Secondary
Myocardial Infarction Other Serious 2/1/2010 79 Female 9/29/2010 Physician Norway
Primary
Concomitant
Sepsis Death 8/11/2010 77 Male 10/7/2010 Consumer France
Primary
Concomitant
Tachycardia 51 Female 11/1/2010 United States
Primary
Secondary
Vision Blurred Other Serious 1/1/2008 72 Male 214 lb 11/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 1/1/2009 88 Female 137 lb 11/9/2010 Consumer Brazil
Primary
Secondary
Concomitant
Tuberculosis Other Serious 6/24/2010 48 Male 139 lb 11/17/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/15/2010 71 Female 145 lb 12/2/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2010 58 Female 11/30/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/15/2010 71 Female 145 lb 12/13/2010 Physician United States
Primary
Concomitant
Rash Generalised Other Serious 1/1/2008 72 Male 214 lb 1/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Other Serious 1/1/2010 74 Male 247 lb 1/28/2011 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 3/1/2010 72 Female 163 lb 2/9/2011 Physician Germany
Primary
Concomitant
Drug Ineffective Other Serious 3/1/2010 72 Female 163 lb 2/22/2011 Physician Germany
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 3/1/2010 72 Female 163 lb 3/10/2011 Physician Germany
Primary
Concomitant
Dysgeusia 1/1/2009 70 Male 195 lb 3/17/2011 Physician United States
Primary
Concomitant
Urticaria Other Serious 2/5/2010 50 Female 206 lb 3/29/2011 Physician United States
Primary
Concomitant
Palpitations 10/1/2009 50 Female 219 lb 4/21/2011 Consumer United States
Primary
Secondary
Concomitant
Generalised Oedema Hospitalization 2/1/2011 70 Male 4/29/2011 Physician Bulgaria
Primary
Concomitant
Unevaluable Event 11/27/2010 73 Male 163 lb 2/7/2011 Consumer United States
Primary
Concomitant
Drug Hypersensitivity Hospitalization 44 Female 4/20/2011 Physician United States
Primary
Concomitant
Headache 12/1/2010 75 Female 5/4/2011 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 4/1/2011 85 Male 5/4/2011 Consumer United States
Primary
Concomitant
Balance Disorder Hospitalization 12/4/2008 71 Male 215 lb 5/4/2011 Physician United States
Primary
Secondary
Concomitant
Apnoea Life Threatening 17 Female 5/4/2011 Other Health Professional Poland
Primary
Secondary
Pruritus 1/1/2011 63 Male 5/6/2011 Consumer United States
Primary
Concomitant
Nasal Congestion Hospitalization Male 5/6/2011 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 17 Female 5/6/2011 Other Health Professional Poland
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 3/1/2011 85 Male 5/6/2011 Consumer United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 4/11/2011 84 Female 5/6/2011 Physician United States
Primary
Concomitant
Palpitations 1/1/2011 75 Female 5/6/2011 Consumer United States
Primary
Concomitant
Cardiac Pacemaker Insertion Hospitalization 4/1/2011 77 Male 5/10/2011 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 3/22/2011 64 Male 189 lb 5/10/2011 Physician United States
Primary
Secondary
Concomitant
Hemiparesis Death 67 Male 5/10/2011 Consumer Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/2/2011 Female 5/10/2011 Consumer Switzerland
Primary
Concomitant
Blood Pressure Decreased Other Serious 3/1/2011 82 Male 5/12/2011 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/24/2011 54 Male 170 lb 5/12/2011 Physician United States
Primary
Concomitant
Increased Tendency To Bruise 12/15/2010 84 Male 5/12/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 4/1/2011 85 Male 5/12/2011 Consumer United States
Primary
Concomitant
Drug Dose Omission Hospitalization 3/26/2011 75 Female 5/11/2011 Consumer Canada
Primary
Concomitant
Joint Range Of Motion Decreased Death 5/5/2009 54 Male 269 lb 5/13/2011 Consumer United States
Primary
Secondary
Concomitant
Headache 85 Female 172 lb 5/13/2011 Physician United States
Primary
Concomitant
Muscular Weakness Other Serious 12/1/2003 73 Male 194 lb 5/13/2011 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 12/1/2003 73 Male 194 lb 5/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Death Male 213 lb 5/13/2011 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 Male 185 lb 5/13/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Injury Hospitalization Male 5/13/2011 Lawyer United States
Primary
Concomitant
Dyspnoea 2/10/2011 72 Male 5/16/2011 Consumer United States
Primary
Concomitant
Depression Death 10/12/2003 77 Female 128 lb 5/16/2011 Lawyer United States
Primary
Concomitant
Cholecystitis Other Serious 7/5/2006 36 Female 160 lb 5/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Oedema Peripheral 1/1/2011 63 Male 6/8/2011 Other Health Professional United States
Primary
Concomitant
Tinnitus Hospitalization 4/28/2011 60 Female 165 lb 6/16/2011 Consumer China
Primary
Concomitant
Haemorrhoids Other Serious 5/31/2011 84 Male 191 lb 6/17/2011 Pharmacist United States
Primary
Concomitant

Drug Data