Amlodipine Besylate combined with Metformin Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 10/27/2005 74 Female 1/6/2006 Other Health Professional France
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 12/9/2005 75 Male 176 lb 1/12/2006 Physician Japan
Primary
Concomitant
Joint Swelling 12/20/2004 73 Male 201 lb 1/30/2006 Consumer Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Required Intervention 12/9/2005 75 Male 176 lb 2/6/2006 Physician Japan
Primary
Secondary
Concomitant
Reversible Ischaemic Neurological Deficit Other Serious 5/25/2006 Male 6/30/2006 Physician Germany
Primary
Secondary
Concomitant
Blood Glucose Increased 8/1/2006 Male 205 lb 10/2/2006 Consumer United States
Primary
Concomitant
Surgery Hospitalization 70 Male 10/21/2006 United States
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 56 Female 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 64 Female 12/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Sensation Of Heaviness Other Serious Female 1/9/2007 Consumer Brazil
Primary
Secondary
Concomitant
Sensation Of Heaviness Other Serious Female 1/12/2007 Consumer Brazil
Primary
Secondary
Concomitant
Sensation Of Heaviness Other Serious Female 1/23/2007 Consumer Brazil
Primary
Secondary
Concomitant
Nausea Other Serious 11/16/2006 71 Male 210 lb 11/16/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 64 Female 3/8/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/15/2007 Male 205 lb 4/19/2007 Consumer Canada
Primary
Concomitant
Head Injury Hospitalization 4/13/2007 5/8/2007 Germany
Primary
Secondary
Concomitant
Syncope Other Serious 6/26/2007 59 Female 181 lb 7/6/2007 Consumer Brazil
Primary
Concomitant
Pharyngolaryngeal Pain Other Serious 7/22/2007 Female 132 lb 8/8/2007 Consumer Brazil
Primary
Concomitant
Amnesia 4/6/2007 65 Male 280 lb 7/10/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 62 Male 183 lb 8/10/2007 Consumer United States
Primary
Concomitant
Weight Decreased 2/1/2007 64 Male 230 lb 11/16/2007 Physician United States
Primary
Concomitant
Tremor 4/1/2007 63 Female 10/9/2007 Consumer United States
Primary
Concomitant
Vomiting 5/1/2007 39 Male 10/8/2007 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 5/5/2007 81 Male 12/21/2007 Germany
Primary
Concomitant
Tachycardia Hospitalization 10/17/2007 55 Female 165 lb 1/23/2008 Physician United States
Primary
Concomitant
Oesophageal Pain Other Serious 1/29/2008 Male 250 lb 2/5/2008 Pharmacist United States
Primary
Concomitant
Abasia Disability 11/1/2007 Female 2/20/2008 Consumer Brazil
Primary
Concomitant
Throat Irritation 10/4/2007 59 Male 201 lb 3/10/2008 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 6/1/2007 71 Male 2/15/2008 United States
Primary
Concomitant
Throat Tightness Hospitalization 3/2/2008 52 Male 3/25/2008 Japan
Primary
Secondary
Concomitant
Peripheral Ischaemia Hospitalization 2/12/2008 79 Female 139 lb 3/28/2008
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 208 lb 4/3/2008 Physician United States
Primary
Concomitant
Vasculitis Hospitalization 12/28/2007 57 Male 4/10/2008 Germany
Primary
Concomitant
Haemorrhage Other Serious Male 262 lb 4/22/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious Male 262 lb 5/1/2008 Physician United States
Primary
Concomitant
Melaena Other Serious 3/28/2008 Male 262 lb 5/23/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/28/2007 57 Male 5/16/2008 Germany
Primary
Concomitant
Seborrhoeic Dermatitis Other Serious 12/28/2007 57 Male 6/2/2008 Germany
Primary
Concomitant
Weight Decreased 1/1/2007 54 Male 237 lb 4/10/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 5/1/2008 70 Male 7/11/2008 Physician France
Primary
Secondary
Concomitant
Throat Irritation 10/4/2007 59 Male 201 lb 7/22/2008 Consumer United States
Primary
Secondary
Concomitant
Infarction Death 71 Female 154 lb 7/25/2008 Consumer Brazil
Primary
Concomitant
Reaction To Drug Excipients Other Serious 1/1/2008 73 Male 220 lb 7/25/2008 Other Health Professional United States
Primary
Concomitant
Throat Tightness Other Serious 1/1/2008 69 Female 8/4/2008 United States
Primary
Concomitant
Nausea 4/6/2008 69 Female 270 lb 7/7/2008 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased 10/1/2007 58 Male 197 lb 8/15/2008 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/1/2008 70 Male 8/21/2008 Physician France
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/20/2006 Female 192 lb 9/8/2008 Korea, Republic Of
Primary
Concomitant
Renal Failure Acute Other Serious 5/1/2008 70 Male 9/5/2008 Physician France
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 1/1/2008 73 Male 220 lb 9/11/2008 United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2003 39 Male 370 lb 9/24/2008 Other Health Professional United States
Primary
Concomitant
Pruritus Hospitalization 6/29/2006 71 Male 9/25/2008 Japan
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 66 Male 10/17/2008 Consumer United Kingdom
Primary
Secondary
Sepsis Hospitalization 2/20/2006 Female 192 lb 11/5/2008 Korea, Republic Of
Primary
Concomitant
Tachypnoea Hospitalization 11/14/2008 Female 172 lb 11/14/2008 United States
Primary
Concomitant
Tachypnoea Hospitalization 11/14/2008 Female 172 lb 11/17/2008 United States
Primary
Secondary
Concomitant
Pain In Extremity 8/13/2008 70 Female 11/14/2008 Consumer United States
Primary
Concomitant
Hypersensitivity Other Serious 10/4/2008 77 Male 12/18/2008 United Kingdom
Primary
Concomitant
Renal Failure Acute Life Threatening 12/10/2008 56 Male 1/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 11/17/2008 1/16/2009 Physician Poland
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 1/3/2009 85 Female 1/22/2009 Other Health Professional Germany
Primary
Concomitant
Obesity Other Serious 42 Male 1/29/2009 Other Health Professional United Kingdom
Primary
Secondary
International Normalised Ratio Increased Hospitalization 9/28/2007 84 Female 2/12/2009 France
Primary
Secondary
Concomitant
Skin Odour Abnormal Hospitalization 2/10/2009 64 Male 135 lb 2/22/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 9/28/2007 84 Female 2/24/2009 France
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 1/1/2008 Female 220 lb 2/26/2009 Physician United States
Primary
Secondary
Concomitant
Superficial Injury Of Eye Other Serious 7/14/2008 57 Female 220 lb 3/4/2009 Physician United States
Primary
Secondary
Concomitant
Myalgia Life Threatening 3/8/2009 Male 143 lb 3/16/2009 Physician India
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 2/2/2009 Male 3/16/2009 Physician Germany
Primary
Concomitant
Myalgia Life Threatening 3/8/2009 Male 143 lb 3/16/2009 Physician India
Primary
Secondary
Concomitant
Deafness 3/1/2009 66 Male 3/16/2009 Consumer United States
Primary
Concomitant
Insomnia Hospitalization 12/15/2006 53 Female 3/17/2009 Korea, Democratic People's Republic Of
Primary
Concomitant
Weight Decreased Other Serious 5/1/2008 Female 212 lb 4/2/2009 Physician France
Primary
Concomitant
Respiratory Tract Infection Hospitalization 3/8/2009 Male 143 lb 4/2/2009 Physician India
Primary
Concomitant
Weight Increased Other Serious 8/28/2002 71 Female 167 lb 4/3/2009 United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 2/23/2009 56 Male 325 lb 4/3/2009 Physician United Kingdom
Primary
Concomitant
Skin Fissures Other Serious 2/2/2009 Male 4/3/2009 Physician Germany
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/17/2008 4/6/2009 Physician Poland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2008 Female 212 lb 4/9/2009 Physician France
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/30/2008 Male 4/10/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/1/2009 Male 190 lb 4/9/2009 Consumer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 4/2/2009 76 Unknown 5/8/2009 Physician Denmark
Primary
Secondary
Concomitant
Prosthesis Implantation Other Serious 1/1/2009 Female 134 lb 5/13/2009 Physician Brazil
Primary
Concomitant
Vomiting Other Serious 5/5/2009 Female 134 lb 5/15/2009 Physician Brazil
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 4/10/2009 Male 290 lb 5/12/2009 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 51 Male 6/2/2009 Other Health Professional Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 39 Male 368 lb 6/3/2009 United States
Primary
Concomitant
Toxic Encephalopathy Hospitalization 51 Male 6/2/2009 Other Health Professional Korea, Republic Of
Primary
Concomitant
Malaise Other Serious 5/11/2009 76 Male 6/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Intracranial Pressure Increased Hospitalization 51 Male 6/10/2009 Physician Korea, Republic Of
Primary
Concomitant
Trismus Hospitalization 51 Male 6/19/2009 Other Health Professional Germany
Primary
Concomitant
Malaise Other Serious 5/11/2009 76 Male 6/18/2009 Consumer United Kingdom
Primary
Concomitant
Encephalopathy Hospitalization 51 Male 6/23/2009 Other Health Professional Korea, Republic Of
Primary
Concomitant
Vertigo Other Serious Female 7/1/2009 Australia
Primary
Concomitant
Poisoning 17 Female 7/13/2009 United States
Primary
Concomitant
Pain In Extremity Female 225 lb 8/22/2009 Physician United States
Primary
Concomitant
Traumatic Haematoma Hospitalization 11/1/2008 83 Male 8/20/2009 France
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 1/1/2009 Male 291 lb 8/25/2009 Consumer United States
Primary
Secondary
Concomitant
Skin Ulcer 1/1/2005 Female 269 lb 9/11/2009 Physician United States
Primary
Concomitant
Diabetes Mellitus Other Serious 1/1/2002 32 Female 319 lb 9/23/2009 United States
Primary
Concomitant
Polydipsia Male 164 lb 9/24/2009 Consumer United States
Primary
Concomitant
Vertigo Hospitalization 7/1/2009 53 Female 10/9/2009 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Idiopathic Urticaria Hospitalization 8/24/2009 Female 10/22/2009 Other Health Professional France
Primary
Concomitant
Hydrocephalus Hospitalization 1/1/2009 Female 10/27/2009 United States
Primary
Concomitant
Viral Infection Hospitalization 8/24/2009 71 Female 10/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Other Serious 8/24/2009 10/30/2009 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
Lung Disorder Other Serious 5/7/2009 77 Female 10/19/2009 Japan
Primary
Concomitant
Urine Abnormality Other Serious 83 Female 12/1/2009 Consumer Brazil
Primary
Concomitant
Temporal Arteritis Other Serious 1/1/2009 Female 102 lb 12/1/2009 Consumer United States
Primary
Concomitant
Cerebral Infarction Hospitalization 10/20/2009 Female 141 lb 12/15/2009 Japan
Primary
Concomitant
Renal Impairment Other Serious 11/24/2009 66 Male 12/11/2009 Japan
Primary
Concomitant
Overdose Other Serious 39 Male 1/5/2010 United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2008 52 Female 1/11/2010 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2008 51 Male 1/11/2010 Physician United States
Primary
Secondary
Urticaria Other Serious 7/23/2009 Female 1/13/2010 Physician United States
Primary
Concomitant
Intentional Drug Misuse Other Serious 1/1/2008 52 Female 1/15/2010 United States
Primary
Secondary
Intentional Drug Misuse Other Serious 1/1/2008 51 Male 1/15/2010 United States
Primary
Secondary
Trismus Hospitalization 51 Male 1/19/2010 Physician Korea, Republic Of
Primary
Concomitant
Gastric Dilatation Hospitalization 12/31/2009 Female 132 lb 2/2/2010 Physician China
Primary
Concomitant
Overdose Other Serious 39 Male 3/1/2010 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 1/23/2010 67 Female 3/5/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Male 4/19/2010 United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious Female 6/4/2010 Consumer United States
Primary
Interacting
Brain Stem Infarction Hospitalization 5/19/2010 64 Male 203 lb 6/24/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/15/2009 60 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 56 Male 200 lb 7/6/2010 Physician United States
Primary
Concomitant
Product Substitution Issue Other Serious 69 Male 299 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Splenomegaly Hospitalization 1/1/2010 67 Female 294 lb 7/13/2010 Physician United States
Primary
Concomitant
Frustration 1/1/2008 64 Male 266 lb 7/31/2010 Consumer United States
Primary
Secondary
Concomitant
Swelling Face Life Threatening 6/21/2010 64 Male 8/10/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombotic Cerebral Infarction Hospitalization 10/8/2009 59 Female 141 lb 8/11/2010 Physician Japan
Primary
Concomitant
Swelling Face Life Threatening 6/21/2010 64 Male 8/16/2010 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/28/2010 85 Female 126 lb 8/17/2010 Physician Japan
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious Female 187 lb 8/20/2010 Other Health Professional Germany
Primary
Concomitant
Visual Acuity Reduced Disability 9/1/2009 76 Female 198 lb 8/30/2010 Physician United States
Primary
Concomitant
Pregnancy Other Serious 29 Male 9/3/2010 Other Health Professional Germany
Primary
Secondary
Blood Glucose Increased Other Serious 68 Male 7/9/2010 United States
Primary
Secondary
Vomiting 6/4/2010 69 Female 8/13/2010 Consumer United States
Primary
Concomitant
Stomatitis Life Threatening 7/13/2010 81 Female 92 lb 9/13/2010 Physician Japan
Primary
Secondary
Concomitant
Hypotension 7/9/2008 Male 9/14/2010 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Other Serious Female 9/16/2010 Consumer United States
Primary
Interacting
Pneumonia Hospitalization 8/21/2010 85 Male 215 lb 10/27/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 8/21/2010 85 Male 215 lb 10/29/2010 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious 9/20/2010 59 Male 11/2/2010 Physician Germany
Primary
Secondary
Squamous Cell Carcinoma Hospitalization 8/21/2010 85 Male 215 lb 11/12/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 9/28/2010 67 Male 187 lb 11/15/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective 11/1/2009 75 Male 11/23/2010 Consumer United States
Primary
Concomitant
Wrist Fracture Other Serious Female 6/4/2010 Consumer United States
Primary
Interacting

Drug Data