Amlodipine Besylate combined with Glyburide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Prothrombin Time Prolonged Required Intervention 12/9/2005 75 Male 176 lb 1/12/2006 Physician Japan
Primary
Concomitant
Joint Swelling 12/20/2004 73 Male 201 lb 1/30/2006 Consumer Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Required Intervention 12/9/2005 75 Male 176 lb 2/6/2006 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 2/22/2005 74 Female 2/8/2006 Japan
Primary
Concomitant
Haematocrit Decreased Hospitalization 8/1/2004 70 Male 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 1/4/2005 85 Male 180 lb 3/10/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 11/20/2003 66 Male 209 lb 5/18/2006 Lawyer United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 11/2/2005 71 Male 216 lb 6/27/2006 Other Health Professional Germany
Primary
Concomitant
Rash Other Serious 63 Male 185 lb 10/19/2006 Consumer France
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 8/10/2006 74 Male 10/24/2006 Japan
Primary
Concomitant
No Reaction On Previous Exposure To Drug Life Threatening 11/29/2006 72 Male 123 lb 12/14/2006 Physician Japan
Primary
Concomitant
Urinary Incontinence Hospitalization 8/10/2006 74 Male 12/19/2006 Japan
Primary
Concomitant
Hypertension Life Threatening 4/12/2001 Female 1/12/2007 Other Health Professional France
Primary
Secondary
Concomitant
Nausea Other Serious 11/16/2006 71 Male 210 lb 11/16/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 4/4/2005 63 Male 185 lb 1/30/2007 Consumer France
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 8/10/2006 74 Male 6/25/2007 Japan
Primary
Concomitant
Feeling Abnormal Hospitalization 6/16/2007 Male 139 lb 8/9/2007 Physician Japan
Primary
Concomitant
Feeling Abnormal Hospitalization 6/16/2007 Male 139 lb 9/4/2007 Physician Japan
Primary
Concomitant
Pericardial Effusion Hospitalization 8/21/2007 59 Female 9/17/2007 Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 12/8/2006 Male 9/19/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/2/2006 Male 10/11/2007 Physician Japan
Primary
Concomitant
Middle Insomnia 87 Female 189 lb 10/5/2007 Consumer United States
Primary
Concomitant
Weight Decreased 2/1/2007 64 Male 230 lb 11/16/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 11/22/2007 74 Male 12/12/2007 Physician Japan
Primary
Concomitant
Shock Haemorrhagic Life Threatening 10/15/2007 84 Male 12/11/2007 Japan
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 8/21/2007 59 Female 12/13/2007 Other Health Professional Japan
Primary
Concomitant
Vomiting 5/1/2007 39 Male 10/8/2007 Consumer United States
Primary
Concomitant
Shock Haemorrhagic Life Threatening 10/15/2007 84 Male 12/21/2007 Japan
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 52 Female 258 lb 1/18/2008 Other Health Professional Canada
Primary
Concomitant
Rhabdomyolysis Other Serious 11/20/2007 74 Male 1/22/2008 Physician Japan
Primary
Concomitant
Respiratory Disorder Death 11/1/2007 70 Female 1/15/2008 Physician Japan
Primary
Concomitant
Muscular Weakness Other Serious 52 Female 258 lb 1/25/2008 Other Health Professional Canada
Primary
Concomitant
Oesophageal Pain Other Serious 1/29/2008 Male 250 lb 2/5/2008 Pharmacist United States
Primary
Concomitant
Swollen Tongue Other Serious 65 Female 209 lb 2/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Discharge Hospitalization 1/1/2008 40 Male 4/11/2008 Consumer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 7/8/2007 74 Female 6/11/2008 Other Health Professional France
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection 2/1/2008 57 Male 174 lb 8/15/2008 Physician United States
Primary
Concomitant
Lymphoma Hospitalization 8/27/2007 Female 137 lb 9/19/2008 Physician Japan
Primary
Concomitant
Vision Blurred Disability 5/24/2008 75 Female 9/25/2008 Consumer United States
Primary
Concomitant
Vision Blurred Disability 1/1/2008 75 Female 243 lb 10/30/2008 Other Health Professional United States
Primary
Concomitant
Urticaria 2/1/2008 65 Male 11/14/2008 United States
Primary
Concomitant
Pain In Extremity 8/13/2008 70 Female 11/14/2008 Consumer United States
Primary
Concomitant
Vision Blurred Disability 1/1/2008 75 Female 243 lb 3/19/2009 Other Health Professional United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 1/1/2009 57 Male 5/11/2009 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 4/26/2009 57 Male 5/29/2009 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 4/26/2009 57 Male 7/1/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/27/2002 54 Male 200 lb 7/7/2009 United States
Primary
Concomitant
Upper Respiratory Tract Congestion Other Serious Male 195 lb 9/3/2009 Consumer United States
Primary
Concomitant
Cerebral Infarction Hospitalization 8/18/2008 73 Female 9/17/2009 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 9/25/2009 66 Male 201 lb 10/26/2009 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/25/2009 66 Male 201 lb 11/20/2009 Other Health Professional France
Primary
Secondary
Concomitant
Traumatic Fracture Hospitalization 6/30/2008 60 Female 1/4/2010 Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 8/18/2008 73 Female 1/29/2010 Japan
Primary
Concomitant
Traumatic Fracture Hospitalization 6/30/2008 60 Female 2/8/2010 Japan
Primary
Concomitant
Traumatic Fracture Hospitalization 6/30/2006 60 Female 3/12/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 8/18/2008 73 Female 4/12/2010 Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 9/25/2009 66 Male 201 lb 4/30/2010 Other Health Professional France
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 4/26/2009 57 Male 4/30/2010 Physician Germany
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 7/14/2006 59 Female 127 lb 6/29/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Death 10/15/2007 86 Female 7/21/2010 Lawyer United States
Primary
Concomitant
Frustration 1/1/2008 64 Male 266 lb 7/31/2010 Consumer United States
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 4/26/2009 57 Male 8/3/2010 Physician Germany
Primary
Concomitant
Hypoglycaemia Other Serious 4/1/2010 88 Female 8/11/2010 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 4/1/2010 88 Female 8/13/2010 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 4/17/2010 88 Female 8/24/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/1/2005 56 Female 151 lb 8/30/2010 Physician United States
Primary
Concomitant
Pregnancy Other Serious 29 Male 9/3/2010 Other Health Professional Germany
Primary
Secondary
Wheezing Other Serious 1/1/2007 86 Female 9/16/2010 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 5/8/2009 75 Male 148 lb 10/18/2010 Physician Japan
Primary
Concomitant
Breast Cancer Life Threatening 2/23/2010 79 Female 134 lb 10/21/2010 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 10/23/2010 77 Male 176 lb 12/13/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Intentional Drug Misuse Death 40 Male 1/4/2011 Physician United States
Primary
Secondary
Restless Legs Syndrome Other Serious Male 1/7/2011 Lawyer United States
Primary
Concomitant
Dizziness Death 1/1/2007 86 Female 1/27/2011 Other Health Professional United States
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 9/28/2010 86 Female 2/11/2011 Other Health Professional Sweden
Primary
Concomitant
Hypertension Other Serious 6/1/2010 71 Female 2/14/2011 Consumer Brazil
Primary
Concomitant
Rash 1/1/2009 61 Female 3/17/2011 Consumer United States
Primary
Concomitant
Foreign Body 1/13/2010 68 Female 254 lb 3/17/2011 Consumer United States
Primary
Concomitant
Nerve Injury Other Serious 1/27/2011 58 Female 276 lb 3/31/2011 Consumer United States
Primary
Concomitant
Hypertension Other Serious 1/1/2004 4/4/2011 Consumer United States
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 2/6/2011 77 Female 4/11/2011 Consumer Germany
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2004 4/22/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 4/13/2011 84 Male 4/28/2011 Consumer United States
Primary
Secondary
Concomitant
Dermatitis Allergic Death 7/5/2008 54 Male 5/5/2011 Physician France
Primary
Concomitant
Blood Pressure Increased Hospitalization 1/1/2011 51 Female 174 lb 5/5/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Pressure Diastolic Decreased Other Serious 7/8/2010 90 Male 86 lb 5/6/2011 Physician Japan
Primary
Secondary
Concomitant
No Adverse Event Death Male 5/9/2011 United States
Primary
Concomitant
Confusional State 4/18/2011 78 Male 5/9/2011 Physician United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 4/1/2011 Male 5/13/2011 Consumer United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Life Threatening 9/1/2010 70 Male 5/22/2011 Physician Germany
Primary
Concomitant
Hypertension Other Serious 6/1/2010 71 Female 6/2/2011 Consumer Brazil
Primary
Concomitant
Gastric Cancer Hospitalization 8/1/2010 76 Male 148 lb 6/10/2011 Physician Japan
Primary
Concomitant
Agitation Hospitalization 1/23/2006 78 Female 157 lb 6/11/2011 Physician Brazil
Primary
Concomitant
Tremor Other Serious 42 Female 240 lb 6/17/2011 Other Health Professional United States
Primary
Concomitant
Productive Cough Hospitalization 42 Female 240 lb 6/17/2011 Other Health Professional United States Minor Outlying Islands
Primary
Concomitant
Gastritis Haemorrhagic Hospitalization 12/20/2010 77 Male 6/9/2011 Other Health Professional Japan
Primary
Concomitant
Death Death 1/1/2011 79 Male 6/21/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/25/2009 66 Male 201 lb 7/5/2011 Other Health Professional France
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 5/21/2011 72 Male 7/14/2011 Physician Japan
Primary
Concomitant
Off Label Use Other Serious Male 7/21/2011 Physician United States
Primary
Concomitant
Multiple Myeloma Death 1/1/2011 79 Male 7/25/2011 Physician United States
Primary
Concomitant
Depression Other Serious 1/1/2008 63 Male 168 lb 7/28/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 5/21/2011 72 Male 174 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 5/22/2011 72 Male 174 lb 8/10/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Other Serious 5/22/2011 72 Male 174 lb 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Haematuria Hospitalization 9/11/2009 Female 8/8/2011 Japan
Primary
Concomitant
Renal Failure Other Serious Male 240 lb 8/11/2011 Consumer United States
Primary
Concomitant
Multiple Myeloma Death 1/1/2011 91 Male 8/16/2011 Physician United States
Primary
Concomitant
Bladder Cancer Life Threatening 10/1/2010 60 Male 8/26/2011 Japan
Primary
Concomitant
Albuminuria Hospitalization 8/1/2009 59 Male 9/7/2011 Other Health Professional Japan
Primary
Concomitant
Bladder Transitional Cell Carcinoma Hospitalization 8/1/2009 59 Male 9/14/2011 Other Health Professional Japan
Primary
Concomitant
Off Label Use Hospitalization 1/19/2011 90 Male 10/12/2011 Physician France
Primary
Concomitant
Multiple Myeloma Other Serious Male 154 lb 10/14/2011 Physician United States
Primary
Concomitant
Cytolytic Hepatitis Hospitalization 5/26/2011 55 Male 11/3/2011 Physician France
Primary
Secondary
Concomitant
Sleep Disorder Due To A General Medical Condition Other Serious Male 154 lb 11/28/2011 Physician United States
Primary
Concomitant
Death Other Serious 7/12/2008 78 Male 189 lb 11/29/2011 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/24/2011 74 Male 12/14/2011 Physician Japan
Primary
Concomitant
Tremor 1/24/2011 74 Male 1/5/2012 Physician Japan
Primary
Concomitant
Off Label Use Other Serious 50 Male 240 lb 11/17/2011 Lawyer United States
Primary
Concomitant
Toxicity To Various Agents Death 40 Male 1/26/2012 Physician United States
Primary
Secondary
Injection Site Erythema Other Serious 1/1/2011 71 Female 217 lb 1/29/2012 Consumer United States
Primary
Concomitant
Bladder Transitional Cell Carcinoma Hospitalization 11/10/2011 74 Male 2/14/2012 Other Health Professional Japan
Primary
Concomitant
Cholecystitis Acute Hospitalization 7/28/2010 51 Male 234 lb 3/16/2012 Physician Germany
Primary
Concomitant
Drug Interaction 1/1/2012 72 Male 220 lb 3/20/2012 Consumer United States
Primary
Interacting
Vascular Calcification Other Serious Male 158 lb 4/5/2012 Lawyer United States
Primary
Concomitant
Oedema Peripheral 4/1/2012 62 Female 309 lb 4/18/2012 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral 4/1/2012 62 Female 309 lb 4/20/2012 Physician United States
Primary
Secondary
Concomitant
Blindness Unilateral Other Serious Male 158 lb 4/24/2012 Lawyer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 4/5/2012 58 Male 4/27/2012 Consumer United States
Primary
Concomitant
Brain Stem Infarction Hospitalization 1/24/2012 67 Male 276 lb 5/23/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pancytopenia Death 5/11/2012 79 Male 170 lb 5/23/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 4/4/2012 58 Male 5/24/2012 Pharmacist United States
Primary
Concomitant
Dialysis Other Serious 4/1/2012 53 Female 185 lb 5/23/2012 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 4/30/2012 53 Male 5/24/2012 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 4/16/2012 66 Male 258 lb 6/11/2012 Other Health Professional United States
Primary
Concomitant
Cataract Other Serious 9/21/2010 7/17/2012 Consumer Finland
Primary
Concomitant
Angioedema 7/23/2012 Consumer United States
Primary
Concomitant
Oedema Peripheral 8/1/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Angioedema 8/8/2012 Consumer United States
Primary
Concomitant
Psychotic Disorder Hospitalization 5/6/2012 60 Male 8/21/2012 Consumer Japan
Primary
Concomitant
Hypoglycaemia Other Serious 4/17/2012 8/24/2012 Physician Japan
Primary
Concomitant
Interacting
Vision Blurred Other Serious 4/16/2012 66 Male 258 lb 4/29/2013 Consumer Us
Primary
Concomitant
Psychotic Disorder Hospitalization 5/6/2012 60 Male 2/26/2013 Consumer Jp
Primary
Concomitant
Renal Failure Acute Hospitalization 5/2012 83 Female 240 lb 9/25/2013 Consumer Us
Primary
Concomitant
Syncope Hospitalization 1/10/2012 81 Female 2/22/2013 Physician Us
Primary
Concomitant
Hypotension 3/8/2013 52 Male 5/15/2013 Physician Us
Primary
Secondary
Concomitant
Rectal Haemorrhage Death 12/25/2011 80 Female 192 lb 9/24/2013 Consumer Us
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious Male 252 lb 5/23/2013 Other Health Professional Us
Primary
Concomitant
Thrombosis Hospitalization 4/2013 83 Female 190 lb 5/31/2013 Other Health Professional Us
Primary
Concomitant
Pain In Extremity Death 2013 Male 9/12/2013 Physician Us
Primary
Concomitant

Drug Data