Amlodipine Besylate combined with Glimepiride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Other Serious 64 Female 1/3/2006 Consumer Japan
Primary
Secondary
Concomitant
Intestinal Stenosis Hospitalization 5/27/2004 Male 1/4/2006 France
Primary
Concomitant
Renal Failure Death 11/17/2005 Female 1/18/2006 Australia
Primary
Concomitant
Sinus Bradycardia Hospitalization 71 Female 6/9/2006 Physician Brazil
Primary
Concomitant
Self-medication Other Serious 4/1/2005 72 Male 6/20/2006 Pharmacist Japan
Primary
Concomitant
Hypoglycaemia Hospitalization 72 Male 6/30/2006 Physician Japan
Primary
Secondary
Concomitant
Pruritus Generalised Life Threatening 6/26/2006 74 Male 7/5/2006 Physician Italy
Primary
Concomitant
Therapy Non-responder Hospitalization 71 Female 8/7/2006 Physician Brazil
Primary
Concomitant
Death Death 67 Female 162 lb 1/30/2006 Physician United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 56 Female 10/10/2006 Physician United States
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 56 Female 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Life Threatening 2/21/2007 44 Male 5/31/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Pruritus Life Threatening 2/21/2007 Male 6/14/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/20/2006 Female 192 lb 6/22/2007 Korea, Republic Of
Primary
Concomitant
Middle Insomnia 3/1/2007 77 Female 328 lb 7/10/2007 Consumer United States
Primary
Concomitant
Granulocyte Count Increased Hospitalization 7/14/2007 64 Male 8/22/2007 Other Health Professional Denmark
Primary
Concomitant
Granulocyte Count Increased Hospitalization 7/14/2007 64 Male 8/31/2007 Other Health Professional Denmark
Primary
Concomitant
Renal Failure Chronic Hospitalization 2/8/2007 75 Male 9/12/2007 Japan
Primary
Concomitant
Melaena Hospitalization 9/13/2007 Male 10/8/2007 Other Health Professional Japan
Primary
Concomitant
Pruritus Life Threatening 2/21/2007 Male 10/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 2/8/2007 75 Male 10/17/2007 Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 10/16/2007 83 Male 11/19/2007 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 10/16/2007 83 Male 11/21/2007 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 10/16/2007 83 Male 12/3/2007 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 8/9/2006 62 Male 12/10/2007 Other Health Professional Japan
Primary
Concomitant
Rhabdomyolysis Life Threatening 11/22/2007 74 Male 12/12/2007 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 11/20/2007 74 Male 1/22/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 8/9/2006 62 Male 2/5/2008 Other Health Professional Japan
Primary
Concomitant
Abasia Disability 11/1/2007 Female 2/20/2008 Consumer Brazil
Primary
Concomitant
Hypoglycaemic Coma Life Threatening 1/19/2008 96 Female 79 lb 3/14/2008 Physician Japan
Primary
Concomitant
Interacting
Pruritus Hospitalization 6/29/2006 71 Male 7/18/2008 Japan
Primary
Concomitant
Nausea 4/6/2008 69 Female 270 lb 7/7/2008 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 2/20/2006 Female 192 lb 9/8/2008 Korea, Republic Of
Primary
Concomitant
Tremor Life Threatening 6/1/2008 Male 198 lb 9/9/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 8/29/2008 Male 123 lb 9/19/2008 Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 6/29/2006 71 Male 9/25/2008 Japan
Primary
Concomitant
Pyrexia Hospitalization 8/29/2008 Male 123 lb 9/26/2008 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/29/2008 Male 123 lb 10/13/2008 Japan
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 10/6/2008 70 Male 10/30/2008 Physician Japan
Primary
Concomitant
Hypertriglyceridaemia Other Serious 10/6/2008 70 Male 11/4/2008 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 2/20/2006 Female 192 lb 11/5/2008 Korea, Republic Of
Primary
Concomitant
Hypertriglyceridaemia 10/6/2008 70 Male 11/11/2008 Physician Japan
Primary
Concomitant
Condition Aggravated Required Intervention 7/30/2007 79 Male 121 lb 11/14/2008 Physician Japan
Primary
Concomitant
Rhinorrhoea 76 Female 11/14/2008 United States
Primary
Concomitant
Pyrexia Hospitalization 8/29/2008 Male 123 lb 12/1/2008 Japan
Primary
Secondary
Concomitant
Hypothyroidism Other Serious 1/28/2009 2/19/2009 Physician Greece
Primary
Secondary
Concomitant
Hypothyroidism Other Serious 1/28/2009 3/6/2009 Physician Greece
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/28/2009 75 Male 174 lb 3/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 6/2/2008 71 Male 198 lb 3/16/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Myalgia Life Threatening 3/8/2009 Male 143 lb 3/16/2009 Physician India
Primary
Secondary
Concomitant
Myalgia Life Threatening 3/8/2009 Male 143 lb 3/16/2009 Physician India
Primary
Secondary
Concomitant
Insomnia Hospitalization 12/15/2006 53 Female 3/17/2009 Korea, Democratic People's Republic Of
Primary
Concomitant
Respiratory Tract Infection Hospitalization 3/8/2009 Male 143 lb 4/2/2009 Physician India
Primary
Concomitant
Weight Decreased Hospitalization 2/1/2009 Male 190 lb 4/9/2009 Consumer United States
Primary
Concomitant
Hypothyroidism Other Serious 1/28/2009 5/7/2009 Physician Greece
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/28/2009 75 Male 174 lb 5/21/2009 Consumer United States
Primary
Secondary
Concomitant
Small Bowel Angioedema Other Serious 56 Female 6/24/2009 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Necrotising Other Serious 3/8/2009 59 Male 209 lb 7/17/2009 Physician France
Primary
Concomitant
Hypothyroidism Other Serious 1/28/2009 76 8/11/2009 Physician Greece
Primary
Secondary
Concomitant
Anaemia Other Serious 8/12/2009 58 Female 8/31/2009 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/28/2009 75 Male 174 lb 8/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 5/7/2009 77 Female 8/31/2009 Japan
Primary
Concomitant
Anaemia Other Serious 8/12/2009 58 Female 9/30/2009 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 9/1/2009 Male 240 lb 9/30/2009 Consumer United States
Primary
Concomitant
Vertigo Hospitalization 7/1/2009 53 Female 10/9/2009 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/25/2009 66 Male 201 lb 10/26/2009 Other Health Professional France
Primary
Secondary
Concomitant
Fatigue Hospitalization 11/2/2009 Male 154 lb 11/11/2009 Physician India
Primary
Secondary
Concomitant
Lung Disorder Other Serious 5/7/2009 77 Female 10/19/2009 Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 9/25/2009 66 Male 201 lb 11/20/2009 Other Health Professional France
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 10/20/2009 Female 141 lb 12/15/2009 Japan
Primary
Concomitant
Influenza Hospitalization 7/1/2009 Male 12/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/20/2009 Female 147 lb 12/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 9/1/2009 69 Male 240 lb 11/17/2009 Consumer United States
Primary
Concomitant
Thrombotic Cerebral Infarction Hospitalization 10/20/2009 Female 141 lb 12/21/2009 Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/20/2009 Female 147 lb 12/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/20/2009 Female 123 lb 1/8/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/20/2009 Female 123 lb 1/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/24/2010 69 Male 86 lb 4/5/2010 Physician Japan
Primary
Concomitant
Metastases To Liver Life Threatening 11/25/2009 70 Female 4/9/2010 Japan
Primary
Concomitant
Skin Exfoliation Hospitalization 3/1/2010 67 Male 4/15/2010 Consumer United States
Primary
Concomitant
Metastases To Liver Life Threatening 11/25/2009 70 Female 4/23/2010 Japan
Primary
Concomitant
Influenza Hospitalization 7/1/2009 65 Male 136 lb 4/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/25/2009 66 Male 201 lb 4/30/2010 Other Health Professional France
Primary
Secondary
Concomitant
Breast Cancer Metastatic Other Serious 58 Female 210 lb 5/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Breast Cancer Metastatic Other Serious 58 Female 210 lb 5/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Metastases To Liver Life Threatening 11/25/2009 70 Female 5/7/2010 Japan
Primary
Concomitant
Dizziness Hospitalization 1/3/2009 76 Female 5/6/2010 Japan
Primary
Concomitant
Metastases To Liver Life Threatening 11/25/2009 70 Female 6/18/2010 Physician Japan
Primary
Concomitant
Movement Disorder Hospitalization 68 Female 6/29/2010 Consumer United States
Primary
Secondary
Concomitant
Lacunar Infarction Hospitalization 9/14/2009 61 Male 6/28/2010 Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 56 Male 200 lb 7/6/2010 Physician United States
Primary
Concomitant
Liver Disorder Hospitalization Female 198 lb 7/9/2010 Consumer United States
Primary
Concomitant
Splenomegaly Hospitalization 1/1/2010 67 Female 294 lb 7/13/2010 Physician United States
Primary
Concomitant
Swelling Face Life Threatening 6/21/2010 64 Male 7/16/2010 Consumer United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization Female 198 lb 7/21/2010 Consumer United States
Primary
Concomitant
Monoparesis Hospitalization 1/13/2010 68 Female 7/27/2010 United States
Primary
Secondary
Concomitant
Vision Blurred 1/1/2008 53 Female 254 lb 8/4/2010 Lawyer United States
Primary
Concomitant
Sepsis Other Serious 5/16/2010 70 Female 200 lb 8/5/2010 Physician United States
Primary
Secondary
Concomitant
Swelling Face Life Threatening 6/21/2010 64 Male 8/10/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombotic Cerebral Infarction Hospitalization 10/8/2009 59 Female 141 lb 8/11/2010 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 56 Male 200 lb 8/13/2010 Physician United States
Primary
Concomitant
Swelling Face Life Threatening 6/21/2010 64 Male 8/16/2010 Consumer United States
Primary
Secondary
Concomitant
Metastases To Liver Life Threatening 11/25/2009 70 Female 8/17/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization Female 198 lb 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Polymyalgia Rheumatica Hospitalization 11/18/2009 74 Female 203 lb 9/20/2010 Physician Germany
Primary
Concomitant
Vision Blurred 1/1/2008 53 Female 254 lb 9/30/2010 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious Female 126 lb 10/5/2010 Consumer Brazil
Primary
Secondary
Concomitant
Breast Cancer Metastatic Other Serious 58 Female 210 lb 10/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Breast Cancer Metastatic Other Serious 58 Female 210 lb 10/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Breast Cancer Metastatic Other Serious 58 Female 210 lb 10/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Movement Disorder Hospitalization 68 Female 10/25/2010 Consumer United States
Primary
Secondary
Concomitant
Syncope Hospitalization Male 11/15/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/17/2009 73 Female 117 lb 11/15/2010 Physician Japan
Primary
Concomitant
Staphylococcus Test Positive Hospitalization 1/1/2010 11/18/2010 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 70 Male 11/22/2010 Consumer United States
Primary
Concomitant
Syncope Hospitalization Male 12/1/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased 1/1/2008 58 Male 12/13/2010 Consumer United States
Primary
Concomitant
Thrombotic Cerebral Infarction Hospitalization 10/8/2009 59 Female 141 lb 12/14/2010 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 12/6/2010 67 Male 1/7/2011 Pharmacist United States
Primary
Concomitant
Drug Ineffective 74 Male 1/6/2011 Consumer United States
Primary
Concomitant
Surgery Other Serious 1/1/2000 80 Female 154 lb 3/17/2011 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2000 80 Female 154 lb 3/24/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 1/23/2011 74 Female 3/28/2011 Physician Germany
Primary
Concomitant
Sepsis Death 1/30/2011 86 Female 99 lb 4/15/2011 Physician Korea, Republic Of
Primary
Concomitant
Pruritus 1/1/2011 63 Male 5/6/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Life Threatening 2/18/2011 95 Female 5/13/2011 Other Health Professional Germany
Primary
Concomitant
Anhedonia Other Serious 3/7/2007 46 Female 160 lb 6/1/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral 1/1/2011 63 Male 6/8/2011 Other Health Professional United States
Primary
Concomitant
Pancytopenia Hospitalization 5/29/2011 60 Male 295 lb 6/5/2011 Consumer United States
Primary
Concomitant
Malaise Hospitalization 9/3/2010 67 Male 6/22/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/29/2011 60 Male 295 lb 6/13/2011 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/25/2009 66 Male 201 lb 7/5/2011 Other Health Professional France
Primary
Secondary
Concomitant
Bacterial Infection Hospitalization 5/29/2011 60 Male 295 lb 6/13/2011 Consumer United States
Primary
Concomitant
Pancreatitis Acute Other Serious 60 Male 7/15/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Disability 10/23/2006 77 Female 106 lb 7/29/2011 Physician Japan
Primary
Concomitant
Appendicitis Hospitalization 7/23/2011 81 Female 8/1/2011 Consumer Sweden
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Death 12/28/2010 83 Female 99 lb 8/26/2011 Physician Japan
Primary
Concomitant
Metabolic Acidosis Hospitalization 64 Female 8/30/2011 Physician Korea, Republic Of
Primary
Secondary
Intentional Overdose Hospitalization 66 Female 8/30/2011 Physician Korea, Republic Of
Primary
Secondary
Intentional Overdose Hospitalization 41 Female 8/30/2011 Physician Korea, Republic Of
Primary
Secondary
Tremor Other Serious 7/13/2011 75 Female 174 lb 7/14/2011 Consumer United States
Primary
Concomitant
Metabolic Alkalosis Hospitalization 41 Female 9/16/2011 Physician Korea, Republic Of
Primary
Secondary
Sick Sinus Syndrome Other Serious 1/1/2011 70 Female 9/28/2011 Physician Japan
Primary
Concomitant
Atrial Fibrillation Other Serious 8/27/2011 71 Female 9/30/2011 Physician Japan
Primary
Concomitant
Gastritis Hospitalization 4/4/2011 53 Male 10/12/2011 Physician Switzerland
Primary
Concomitant
Oedema Peripheral Hospitalization 12/28/2010 83 Female 99 lb 10/21/2011 Physician Japan
Primary
Concomitant
Dysphonia 7/1/2010 66 Female 10/24/2011 Consumer United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 4/1/2011 68 Female 132 lb 10/31/2011 Physician France
Primary
Secondary
Concomitant
Quadriparesis Life Threatening 11/2/2011 75 Male 11/7/2011 Consumer Hungary
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 11/2/2011 75 Male 11/15/2011 Consumer Hungary
Primary
Secondary
Concomitant

Drug Data