Amlodipine Besylate combined with Carvedilol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Silent Myocardial Infarction Other Serious 56 Male 265 lb 2/16/2006 Physician Greece
Primary
Concomitant
Electrocardiogram Q Waves Other Serious 1/19/2006 56 Male 265 lb 2/27/2006 Physician Greece
Primary
Concomitant
Silent Myocardial Infarction Other Serious 56 Male 265 lb 3/3/2006 Physician Greece
Primary
Concomitant
Catheter Site Haemorrhage Hospitalization 10/11/2004 65 Male 217 lb 12/21/2005 United States
Primary
Secondary
Concomitant
Large Intestinal Haemorrhage Other Serious 6/3/2004 82 Female 135 lb 12/21/2005 Consumer United States
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 11/9/2005 49 Female 3/10/2006 Physician Japan
Primary
Concomitant
Stress Ulcer Hospitalization 11/8/2005 49 Female 4/18/2006 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/12/2006 56 Male 132 lb 4/28/2006 Japan
Primary
Concomitant
Death Death 4/22/2006 88 Male 5/8/2006 United States
Primary
Concomitant
Scan Adrenal Gland Abnormal Hospitalization 53 Male 6/16/2006 Other Health Professional United States
Primary
Concomitant
Urticaria Generalised Life Threatening 3/21/2006 51 Male 6/23/2006 Physician Japan
Primary
Concomitant
Somnolence Hospitalization 1/10/2006 74 Male 6/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Therapy Non-responder Life Threatening 10/31/2005 58 Male 6/27/2006 United States
Primary
Secondary
Somnolence Life Threatening 10/13/2005 58 Male 7/17/2006 United States
Primary
Secondary
Jaundice Other Serious 7/13/2006 75 Male 8/9/2006 Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/1/1995 61 Female 8/31/2006 Physician Italy
Primary
Concomitant
Peritonitis Life Threatening 8/22/2006 Male 150 lb 9/27/2006 Physician Germany
Primary
Concomitant
Cerebrovascular Accident Hospitalization 10/1/2005 Female 195 lb 10/6/2006 Consumer United States
Primary
Concomitant
False Positive Laboratory Result Other Serious 7/11/2006 75 Male 10/3/2006 Japan
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 7/30/2006 79 Female 110 lb 10/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 67 Female 162 lb 1/30/2006 Physician United States
Primary
Concomitant
Peritonitis Life Threatening 8/22/2006 Male 150 lb 10/13/2006 Physician Germany
Primary
Concomitant
Pain In Extremity Life Threatening 7/30/2006 79 Female 110 lb 10/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Drug Administration Error Hospitalization 10/13/2006 Male 11/2/2006 Consumer
Primary
Secondary
Concomitant
Neuroendocrine Carcinoma Of The Skin Life Threatening 7/20/2006 80 Female 4/6/2007 Brazil
Primary
Concomitant
Headache Hospitalization 60 Male 4/17/2007 Other Health Professional Norway
Primary
Secondary
Headache Hospitalization 60 Male 4/20/2007 Physician Norway
Primary
Secondary
Headache Hospitalization 60 Male 4/25/2007 Other Health Professional Norway
Primary
Secondary
Thrombosed Varicose Vein Other Serious 12/1/2006 Female 4/27/2007 Consumer United Kingdom
Primary
Concomitant
Neuroendocrine Carcinoma Of The Skin Life Threatening 7/20/2006 80 Female 4/23/2007 Brazil
Primary
Concomitant
Proteinuria Hospitalization 10/15/2003 5 Male 4/26/2007 Korea, Republic Of
Primary
Concomitant
Nausea Hospitalization 5/2/2004 Male 226 lb 5/25/2007 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 10/15/2003 61 Male 5/24/2007 Korea, Republic Of
Primary
Concomitant
Nausea Hospitalization 5/2/2007 Male 226 lb 6/7/2007 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 10/15/2003 5 Male 6/8/2007 Korea, Republic Of
Primary
Concomitant
Nausea Hospitalization 5/2/2007 Male 226 lb 6/25/2007 Physician United States
Primary
Concomitant
Nausea Hospitalization 5/1/2007 Male 226 lb 6/27/2007 Physician United States
Primary
Concomitant
Peritonitis Life Threatening 10/7/2006 72 Female 78 lb 7/20/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 10/15/2003 61 Male 7/31/2007 Korea, Republic Of
Primary
Concomitant
Large Intestine Perforation Life Threatening 10/7/2006 72 Female 78 lb 8/13/2007 Physician Japan
Primary
Secondary
Concomitant
Granulocyte Count Increased Hospitalization 7/14/2007 64 Male 8/22/2007 Other Health Professional Denmark
Primary
Concomitant
Peritonitis Life Threatening 10/7/2006 72 Female 78 lb 8/23/2007 Physician Japan
Primary
Secondary
Concomitant
Granulocyte Count Increased Hospitalization 7/14/2007 64 Male 8/31/2007 Other Health Professional Denmark
Primary
Concomitant
Urinary Tract Infection Other Serious 3/1/2007 Female 10/11/2007 Belgium
Primary
Concomitant
Staphylococcal Infection Other Serious 3/1/2007 Female 10/18/2007 Belgium
Primary
Concomitant
Incorrect Dose Administered Other Serious 7/30/2007 76 Female 88 lb 10/16/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Other Serious 3/1/2007 Female 11/16/2007 Belgium
Primary
Concomitant
Interstitial Lung Disease Life Threatening 10/16/2007 83 Male 11/19/2007 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 10/16/2007 83 Male 11/21/2007 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 10/16/2007 83 Male 12/3/2007 Other Health Professional Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 3/1/2007 Female 12/21/2007 Belgium
Primary
Concomitant
Cardiac Failure Other Serious 11/1/2007 60 Female 12/20/2007 Japan
Primary
Concomitant
Gait Disturbance Hospitalization 8/18/2007 81 Male 101 lb 12/5/2007 Pharmacist Japan
Primary
Concomitant
Nutritional Condition Abnormal Other Serious 3/1/2008 65 Male 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Rate Increased Other Serious 3/24/2008 Female 115 lb 5/13/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/8/2008 Male 110 lb 5/23/2008 Physician Japan
Primary
Secondary
Concomitant
Interacting
Respiratory Rate Increased Other Serious 3/24/2008 Female 115 lb 5/13/2008 Physician Japan
Primary
Secondary
Concomitant
Tumour Embolism Other Serious 3/24/2008 Female 115 lb 7/21/2008 Physician Japan
Primary
Secondary
Concomitant
Low Density Lipoprotein Increased Other Serious 11/27/2006 52 Male 146 lb 8/12/2008 Other Health Professional Japan
Primary
Concomitant
Social Avoidant Behaviour Other Serious 7/1/2008 61 235 lb 8/22/2008 United States
Primary
Concomitant
Restlessness Other Serious 7/1/2008 61 Male 235 lb 9/12/2008 Consumer United States
Primary
Concomitant
Social Avoidant Behaviour Other Serious 7/1/2008 61 Male 235 lb 10/10/2008 Consumer United States
Primary
Concomitant
Blood Glucose Fluctuation 9/1/2008 Male 207 lb 11/26/2008 United States
Primary
Concomitant
Shock Life Threatening 6/2/2007 Male 1/7/2009 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 11/28/2008 52 Female 1/15/2009 Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 11/21/2007 59 Female 95 lb 2/3/2009 Physician Japan
Primary
Secondary
Concomitant
Varicose Vein Hospitalization 1/7/2009 52 Male 338 lb 2/16/2009 United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2008 59 Male 3/13/2009 Consumer Sweden
Primary
Concomitant
Back Pain 1/6/2009 73 Female 146 lb 3/16/2009 Consumer United States
Primary
Concomitant
Pain Death 3/19/2009 74 Male 3/19/2009 Pharmacist United States
Primary
Concomitant
Drug Ineffective Other Serious 12/4/2008 Female 129 lb 3/30/2009 Physician United States
Primary
Concomitant
Hallucination, Visual Hospitalization 2/28/2006 Female 4/2/2009 Consumer
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 11/28/2003 Male 168 lb 4/3/2009 Physician Spain
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 1/31/2009 80 Male 4/28/2009 Spain
Primary
Secondary
Myoclonus Other Serious 79 Male 5/6/2009 Physician United States
Primary
Concomitant
Myoclonus Hospitalization 79 Male 5/14/2009 Physician United States
Primary
Concomitant
Swollen Tongue Disability 3/6/2009 75 Male 8/18/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 6/1/2009 84 Female 8/25/2009 Consumer United States
Primary
Concomitant
Anaemia Other Serious 8/12/2009 58 Female 8/31/2009 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Concomitant
Anaemia Other Serious 8/12/2009 58 Female 9/30/2009 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Septic Shock Hospitalization 2/10/2009 50 Male 109 lb 10/19/2009 Physician Japan
Primary
Concomitant
Septic Shock Hospitalization 2/10/2009 50 Male 109 lb 10/27/2009 Physician Japan
Primary
Concomitant
Syncope Other Serious 1/1/2009 71 Female 10/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
Growth Hormone Deficiency Other Serious 12 Male 161 lb 12/1/2009 Physician Japan
Primary
Secondary
Concomitant
Treatment Noncompliance 10/26/2009 Female 140 lb 12/4/2009 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Required Intervention 75 Male 12/3/2009 Poland
Primary
Secondary
Concomitant
Malaise Hospitalization 11/17/2009 67 Female 12/10/2009 Physician Japan
Primary
Secondary
Concomitant
Throat Irritation Other Serious 11/11/2009 Male 179 lb 11/20/2009 Pharmacist United States
Primary
Concomitant
Procedural Hypotension Other Serious 1/1/2009 57 Female 1/12/2010 Other Health Professional Japan
Primary
Concomitant
Sepsis Hospitalization 1/11/2010 Female 167 lb 1/22/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 11/17/2009 67 Female 1/19/2010 Physician Japan
Primary
Concomitant
Product Quality Issue Other Serious 1/12/2010 75 Male 190 lb 1/29/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/11/2010 Female 159 lb 2/10/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Vomiting Other Serious 73 Female 2/5/2010 Lawyer United States
Primary
Concomitant
Wound Other Serious 73 Female 2/5/2010 Consumer United States
Primary
Concomitant
Throat Tightness Other Serious Male 295 lb 3/10/2010 Consumer United States
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 4/10/2010 67 Female 110 lb 5/26/2010 Physician Japan
Primary
Concomitant
Anaphylactic Shock Life Threatening 4/10/2010 67 Female 110 lb 5/27/2010 Physician Japan
Primary
Concomitant
Tremor Other Serious 2/2/2010 75 Male 160 lb 5/28/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 6/22/2010 Lawyer United States
Primary
Concomitant
Tremor Other Serious 2/2/2010 75 Male 160 lb 6/23/2010 Physician United States
Primary
Concomitant
Death Death Female 123 lb 6/28/2010 Consumer United States
Primary
Concomitant
Death Death Female 123 lb 6/30/2010 Physician United States
Primary
Concomitant
Regurgitation Other Serious 10/12/2009 69 Female 204 lb 6/3/2010 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/1/2010 39 Male 8/17/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 187 lb 8/19/2010 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 29 Male 9/3/2010 Other Health Professional Germany
Primary
Secondary
Weight Increased Other Serious 1/1/1993 43 Male 290 lb 9/17/2010 Consumer United States
Primary
Secondary
Concomitant
Duodenal Ulcer Haemorrhage Hospitalization 6/21/2010 55 Male 9/17/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/1/2010 72 Male 180 lb 10/22/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 187 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious 50 Male 11/23/2010 Consumer United States
Primary
Secondary
Concomitant
Sensitivity Of Teeth 1/1/2009 91 Female 115 lb 11/23/2010 Consumer United States
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 5/18/2009 88 Male 145 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 9/14/2010 12/9/2010 Physician United States
Primary
Concomitant
Tetany Other Serious 6/14/2010 12/9/2010 Other Health Professional Japan
Primary
Concomitant
Pancytopenia Life Threatening 8/18/2010 68 Female 12/10/2010 Physician Japan
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 12/1/2009 85 Female 137 lb 12/10/2010 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/23/2010 77 Male 176 lb 12/13/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Skin Haemorrhage Other Serious 12/29/2009 12/16/2010 Physician United States
Primary
Concomitant
Hypocalcaemia Other Serious 6/14/2010 12/20/2010 Other Health Professional Japan
Primary
Concomitant
Infection 4/1/2010 12/21/2010 Consumer United States
Primary
Concomitant
Syncope Other Serious 12/1/2010 85 Female 137 lb 12/23/2010 Consumer
Primary
Secondary
Concomitant
Rash 8/28/2010 12/23/2010 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 85 Female 137 lb 12/29/2010 Consumer United States
Primary
Secondary
Concomitant
Pain Hospitalization 3/1/2010 75 Female 1/12/2011 Consumer United States
Primary
Concomitant
Syncope Other Serious 12/1/2010 85 Female 137 lb 1/26/2011 Consumer United States
Primary
Secondary
Concomitant
Injection Site Haematoma 6/7/2010 Female 1/29/2011 Consumer United States
Primary
Concomitant
Fluid Overload Hospitalization Female 1/17/2011 United States
Primary
Concomitant
Blood Blister Other Serious 11/11/2010 77 Male 300 lb 2/11/2011 United States
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 9/28/2010 86 Female 2/11/2011 Other Health Professional Sweden
Primary
Concomitant
Hypertension Other Serious 6/1/2010 71 Female 2/14/2011 Consumer Brazil
Primary
Concomitant
Blood Pressure Increased Other Serious 50 Male 2/24/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious 50 Male 2/24/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Blister Other Serious 11/11/2010 77 Male 300 lb 3/23/2011 Pharmacist United States
Primary
Concomitant
Rib Fracture Other Serious 2/1/2010 58 Male 3/24/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Arrest Other Serious 2/1/2010 58 Male 4/1/2011 Consumer United States
Primary
Secondary
Concomitant
Throat Irritation 2/1/2011 72 Male 4/5/2011 Consumer United States
Primary
Secondary
Concomitant
Azotaemia Other Serious 80 Male 104 lb 4/6/2011 Other Health Professional Japan
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 3/24/2011 77 Male 4/13/2011 Physician Denmark
Primary
Secondary
Concomitant
Dyspnoea Other Serious 9/28/2007 53 Male 235 lb 4/14/2011 Other Health Professional United States
Primary
Concomitant
Neutropenia Hospitalization 12/1/2010 81 Male 4/15/2011 Physician Greece
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/9/2011 81 Male 4/18/2011 Physician Greece
Primary
Secondary
Concomitant
Haematemesis Hospitalization 3/1/2011 46 Male 276 lb 4/21/2011 Physician United States
Primary
Concomitant
Oropharyngeal Pain 9/1/2010 63 Male 185 lb 2/7/2011 Consumer United States
Primary
Concomitant
Localised Infection Hospitalization 75 Male 198 lb 4/11/2011 Pharmacist United States
Primary
Concomitant
Pneumonia Respiratory Syncytial Viral Other Serious 4/2/2011 72 Male 172 lb 5/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Death 8/29/2010 58 Male 120 lb 5/6/2011 Physician Brazil
Primary
Secondary
Concomitant

Drug Data