Amitriptyline combined with Pregabalin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Drug Toxicity Death 12/23/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 12/24/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 50 Female 12/24/2008 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2007 34 Female 12/24/2008 Physician United States
Primary
Secondary
Lacunar Infarction Hospitalization 1/25/2009 2/20/2009 Other Health Professional Canada
Primary
Concomitant
Respiratory Arrest Death 50 Female 2/27/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 50 Female 2/27/2009 Physician United States
Primary
Secondary
Cardiac Failure Other Serious 48 Male 3/9/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2007 Female 108 lb 3/12/2009 Physician United States
Primary
Concomitant
Bronchospasm Other Serious 2/10/2009 58 Female 177 lb 3/13/2009 Physician United Kingdom
Primary
Concomitant
Lacunar Infarction Hospitalization 1/25/2009 3/13/2009 Other Health Professional Canada
Primary
Concomitant
Vomiting Death 34 Female 3/31/2009 Physician United States
Primary
Secondary
Completed Suicide Death 50 Female 3/31/2009 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 3/31/2009 Physician United States
Primary
Secondary
Drug Ineffective Other Serious 20 7/1/2009 Physician Czech Republic
Primary
Secondary
Parkinsonism Other Serious 64 8/7/2009 Other Health Professional Argentina
Primary
Concomitant
Flushing 7/1/2008 Female 8/21/2009 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 11/1/2007 Female 98 lb 9/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ulcer Hospitalization 63 Female 9/17/2009 Netherlands
Primary
Secondary
Nausea Other Serious 6/19/2007 47 Female 9/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ulcer Hospitalization 63 Female 10/15/2009 Netherlands
Primary
Secondary
Lower Respiratory Tract Infection Hospitalization 12/25/2008 Female 196 lb 10/21/2009 United Kingdom
Primary
Concomitant
Incoherent Other Serious 49 Female 172 lb 11/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Choroidal Neovascularisation Other Serious 65 12/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 11/1/2007 Female 98 lb 12/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wegener's Granulomatosis Hospitalization 10/14/2008 Male 154 lb 12/11/2009 Physician Canada
Primary
Secondary
Concomitant
Parkinsonism Other Serious 64 Female 12/15/2009 Argentina
Primary
Concomitant
Oral Pain Other Serious 1/26/2007 55 Female 2/17/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/1/2010 56 Female 3/29/2010 Consumer United States
Primary
Concomitant
Metastatic Neoplasm Hospitalization 1/1/2009 48 Female 4/29/2010 Pharmacist Ireland
Primary
Concomitant
Visual Acuity Reduced Other Serious 11/1/2007 24 Female 98 lb 6/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 65 Male 7/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 65 Male 7/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Parkinsonism Other Serious 64 Female 9/16/2010 Other Health Professional Argentina
Primary
Concomitant
Choroidal Neovascularisation Other Serious 65 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Incoherent Other Serious 49 Female 172 lb 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 65 Male 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Traumatic Brain Injury Life Threatening 7/6/2010 29 Male 189 lb 10/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cerebral Artery Occlusion Other Serious 11/24/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vasculitis Hospitalization 10/8/2010 55 Male 157 lb 11/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 9/26/2010 55 Male 157 lb 12/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Subdural Haemorrhage Hospitalization 9/13/2010 40 Female 12/3/2010 Other Health Professional Czech Republic
Primary
Concomitant
Vasculitis Hospitalization 9/26/2010 55 Male 157 lb 12/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Incoherent Other Serious 49 Female 172 lb 11/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Choroidal Neovascularisation Other Serious 65 12/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Parkinsonism Other Serious 64 Female 12/15/2009 Argentina
Primary
Concomitant
Renal Impairment Other Serious 65 Male 7/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Nail Disorder Female 12/21/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 60 Male 12/28/2010 Lawyer United States
Primary
Concomitant
Pericarditis Hospitalization 12/14/2010 Male 151 lb 12/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebral Artery Occlusion Other Serious 1/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nail Disorder Female 1/7/2011 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 10/26/2010 44 Female 212 lb 1/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Venoocclusive Liver Disease Death 35 Male 177 lb 1/24/2011 Pharmacist United States
Primary
Secondary
Concomitant
Sudden Death Death 61 Female 319 lb 2/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Hospitalization 17 Male 2/16/2011 Physician United States
Primary
Secondary
Incorrect Route Of Drug Administration Other Serious 63 Male 165 lb 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cyanosis Other Serious 63 Male 165 lb 2/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Limb Crushing Injury Hospitalization 3/19/2010 26 Male 3/11/2011 Physician France
Primary
Secondary
Concomitant
Generalised Erythema Hospitalization 61 Male 273 lb 3/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2009 49 Female 2/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Tolerance Other Serious 4/14/2011 Other Health Professional United States
Primary
Secondary
Lethargy Hospitalization 4/25/2011 62 Female 104 lb 5/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Surgery Hospitalization 7/29/2011 47 Female 223 lb 12/29/2011 Physician United States
Primary
Concomitant
Accident Death 1/1/2010 46 Male 3/12/2012 Physician Finland
Primary
Concomitant
Accident Death 1/1/2010 33 Male 3/12/2012 Physician Finland
Primary
Concomitant
Poisoning Death 1/1/2010 45 Male 3/12/2012 Physician Finland
Primary
Concomitant
Completed Suicide Death 1/1/2010 29 Female 3/12/2012 Physician Finland
Primary
Concomitant
Accidental Poisoning Death 1/1/2010 33 Male 3/20/2012 Physician Finland
Primary
Concomitant
Accidental Poisoning Death 1/1/2010 46 Male 3/20/2012 Physician Finland
Primary
Concomitant
Completed Suicide Death 1/1/2010 29 Female 3/20/2012 Physician Finland
Primary
Concomitant
Poisoning Death 1/1/2010 45 Male 3/20/2012 Physician Finland
Primary
Concomitant
Accidental Poisoning Death 1/1/2010 33 Male 3/26/2012 Physician Finland
Primary
Concomitant
Accidental Poisoning Death 1/1/2010 46 Male 3/26/2012 Physician Finland
Primary
Concomitant
Poisoning Death 1/1/2010 45 Male 3/27/2012 Physician Finland
Primary
Concomitant
Completed Suicide Death 1/1/2010 29 Female 3/27/2012 Physician Finland
Primary
Concomitant
Circulatory Collapse Other Serious 6/9/2011 56 Female 128 lb 4/11/2012 Physician United Kingdom
Primary
Concomitant
Hyperkalaemia Life Threatening 4/26/2012 52 Female 196 lb 5/17/2012 Other Health Professional United Kingdom
Primary
Concomitant
Accidental Poisoning Death 34 Male 6/26/2012 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 54 Male 4/9/2013 Consumer De
Primary
Secondary
Post Procedural Infection Hospitalization 7/29/2011 47 Female 223 lb 11/4/2013 Physician Us
Primary
Concomitant
Intestinal Obstruction Death 1/22/2012 98 Female 10/1/2012 Physician Gb
Primary
Concomitant
Ischaemic Stroke Death 4/6/2012 Male 172 lb 12/17/2012 Physician Pt
Primary
Concomitant
Toxicity To Various Agents Death 34 Male 12/21/2012 Other Health Professional Us
Primary
Secondary
Chest Discomfort Hospitalization 6/26/2012 70 Female 187 lb 10/2/2012 Consumer Country Not Specified
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/23/2012 66 Male 11/12/2012 Registered Nurse Us
Primary
Concomitant
Sudden Death Death 61 Female 319 lb 9/18/2012 Other Health Professional Gb
Primary
Concomitant
Vomiting Hospitalization 8/14/2012 Female 161 lb 10/5/2012 Physician De
Primary
Secondary
Concomitant
Meningitis Hospitalization 6/2012 79 Female 9/25/2012 Physician Gb
Primary
Concomitant
Maternal Exposure During Pregnancy Other Serious 10/2012 Female 2/6/2013 Other Health Professional Gb
Primary
Concomitant
Osteoarthritis Other Serious 11/7/2011 50 Female 117 lb 10/25/2012 Consumer Co
Primary
Concomitant
Peripheral Coldness Other Serious 71 Male 155 lb 11/9/2012 Other Health Professional Gb
Primary
Concomitant
Urinary Incontinence Hospitalization 8/28/2012 33 Male 11/26/2012 Pharmacist Gb
Primary
Concomitant
Toxicity To Various Agents Death 34 Male 11/28/2012 Other Health Professional Us
Primary
Secondary
Toxicity To Various Agents Death 34 Female 12/7/2012 Other Health Professional Us
Primary
Secondary
Toxicity To Various Agents Death 34 Male 12/14/2012 Physician Us
Primary
Concomitant
Toxicity To Various Agents Death 34 Male 12/11/2012 Other Health Professional Us
Primary
Secondary
Cognitive Disorder Other Serious 53 Male 10/18/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 34 Male 1/16/2013 Other Health Professional Country Not Specified
Primary
Secondary
Pulmonary Embolism Hospitalization 1/2/2013 71 Male 152 lb 2/26/2014 Physician Fr
Primary
Secondary
Concomitant
Suicidal Ideation Disability 6/2012 44 Male 164 lb 2/14/2013 Consumer Gb
Primary
Secondary
Concomitant
Injection Site Pain 6/2012 57 Male 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Suicidal Ideation Other Serious 6/2012 44 Male 164 lb 2/13/2013 Consumer Gb
Primary
Secondary
Concomitant
Suicidal Ideation Disability 6/2012 44 Male 164 lb 2/21/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/4/2013 75 Female 143 lb 6/14/2013 Physician Ie
Primary
Concomitant
Dysgeusia 12/2012 Male 290 lb 2/28/2013 Consumer Country Not Specified
Primary
Concomitant
Sensory Loss Other Serious 7/3/2011 59 Female 176 lb 11/3/2013 Physician Gb
Primary
Concomitant
Death Death Male 3/7/2013 Physician Us
Primary
Secondary
Death Death Male 3/8/2013 Physician Us
Primary
Secondary
Pneumonia Hospitalization Female 205 lb 3/13/2013 Physician Gb
Primary
Concomitant
Suicidal Ideation Life Threatening 6/2012 44 Male 2/20/2013 Consumer Dk
Primary
Secondary
Concomitant
Suicidal Ideation Life Threatening 2012 44 Male 163 lb 2/15/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Craniectomy Hospitalization 11/15/2007 18 Male 77 lb 5/30/2013 Other Health Professional Us
Primary
Concomitant
Status Migrainosus Hospitalization 3/5/2013 47 Female 6/3/2013 Other Health Professional Gb
Primary
Concomitant
Cerebrovascular Accident Death 3/19/2013 57 Male 4/2/2013 Consumer Nl
Primary
Concomitant
Therapeutic Response Decreased Other Serious 53 Male 4/3/2013 Other Health Professional Us
Primary
Secondary
Somnolence Other Serious 53 Male 4/5/2013 Other Health Professional Us
Primary
Secondary
Somnolence Other Serious 53 Male 4/5/2013 Other Health Professional Us
Primary
Secondary
Somnolence Other Serious 53 Male 4/11/2013 Other Health Professional Us
Primary
Secondary
Substance Abuse Other Serious 3/20/2013 61 Female 172 lb 4/29/2013 Physician It
Primary
Concomitant
Product Substitution Issue Hospitalization 2/2013 72 Female 126 lb 10/25/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 3/24/2013 52 Female 5/10/2013 Other Health Professional Ch
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/25/2013 48 Female 10/29/2013 Physician Gb
Primary
Concomitant
Lethargy Other Serious 53 Male 6/26/2013 Physician In
Primary
Secondary
Urine Output Decreased Hospitalization 5/25/2013 74 Female 220 lb 9/5/2013 Physician Gb
Primary
Concomitant
Thrombocytopenia Death 6/6/2012 71 Male 6/11/2013 Consumer Gb
Primary
Secondary
Concomitant
Pruritus Other Serious 5/1/2013 49 Female 6/11/2013 Pharmacist Gb
Primary
Concomitant
Urinary Incontinence Other Serious 53 Male 6/13/2013 Other Health Professional In
Primary
Secondary
Polymedication Other Serious 53 Male 6/19/2013 Physician In
Primary
Secondary
Granulocytopenia Other Serious 1/12/2012 82 Male 160 lb 6/27/2013 Other Health Professional Us
Primary
Concomitant
Intentional Drug Misuse Death Male 7/3/2013 Other Health Professional Us
Primary
Secondary
Osteosarcoma Metastatic Other Serious 47 Female 7/12/2013 Physician Au
Primary
Concomitant
Tunnel Vision Other Serious 42 Female 273 lb 7/15/2013 Physician Gb
Primary
Concomitant
Pancytopenia Life Threatening 4/14/2013 88 Female 157 lb 7/15/2013 Physician Gb
Primary
Concomitant
Pancytopenia Hospitalization 4/14/2013 88 Female 157 lb 7/16/2013 Physician Gb
Primary
Concomitant
Diabetes Mellitus Life Threatening 6/3/2013 47 Male 159 lb 11/26/2013 Physician Gb
Primary
Concomitant
Pruritus Other Serious 2010 66 Female 8/5/2013 Other Health Professional Gb
Primary
Concomitant
Plasma Cell Myeloma Death Female 190 lb 8/15/2013 Physician Gb
Primary
Concomitant
Heart Rate Increased Disability 6/3/2013 63 Female 141 lb 8/14/2013 Physician Gb
Primary
Concomitant
Heart Rate Increased Disability 6/3/2013 63 Female 141 lb 8/20/2013 Physician Gb
Primary
Concomitant
Heart Rate Increased Disability 6/3/2013 63 Female 141 lb 8/21/2013 Physician Gb
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening NotSpecified 8/30/2013 Other Health Professional Gb
Primary
Secondary
Suicidal Ideation Other Serious 5/9/2013 45 Male 10/16/2013 Pharmacist Au
Primary
Concomitant
Toxicity To Various Agents Death 50 Male 9/9/2013 Other Health Professional Gb
Primary
Secondary
Vision Blurred Other Serious 50 Female 168 lb 9/17/2013 Consumer Gb
Primary
Concomitant
Toxicity To Various Agents Death 50 Male 9/16/2013 Other Health Professional Gb
Primary
Secondary
Dyspnoea Hospitalization 8/2/2012 NotSpecified 9/25/2013 Consumer De
Primary
Secondary
Concomitant
Hallucination, Visual Other Serious 10/2/2011 57 Male 165 lb 11/21/2013 Physician Jp
Primary
Concomitant
Interacting
Somnambulism Other Serious 1/2012 38 Female 214 lb 9/9/2013 Us
Primary
Secondary
Concomitant
Photosensitivity Reaction Disability 9/9/2013 54 Female 143 lb 10/2/2013 Other Health Professional Gb
Primary
Concomitant

Drug Data