Amitriptyline combined with Oxycodone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Arrest Death 1/1/2007 12/24/2008 Physician United States
Primary
Secondary
Weight Increased Other Serious 1/1/2006 Female 170 lb 12/31/2008 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 24 Male 2/24/2009 Physician United States
Primary
Secondary
Psychotic Disorder Other Serious 7/7/2008 Female 150 lb 2/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Completed Suicide Death 28 Female 2/24/2009 Physician United States
Primary
Secondary
Drug Interaction Disability 45 Female 2/20/2009 Canada
Primary
Concomitant
Multiple Myeloma Death 1/13/2009 Male 2/26/2009 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 3/1/2006 Male 260 lb 3/5/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 45 Male 6/17/2009 Consumer United States
Primary
Secondary
Concomitant
Tunnel Vision Disability 5/15/2009 45 6/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Neurotoxicity Other Serious 69 6/22/2009 Other Health Professional Ireland
Primary
Concomitant
Weight Decreased Other Serious 45 Male 6/30/2009 Consumer United States
Primary
Secondary
Concomitant
Homicide Other Serious 4/1/2009 34 Male 6/29/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/13/2002 42 Male 213 lb 7/15/2009 United States
Primary
Concomitant
Vomiting 4/1/2009 Female 7/15/2009 Consumer United States
Primary
Secondary
Tachycardia Other Serious 1/1/2002 52 Female 140 lb 7/16/2009 United States
Primary
Concomitant
Vertigo Hospitalization 2/14/2009 Male 185 lb 7/21/2009
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/9/2008 65 7/28/2009 Physician Germany
Primary
Secondary
Concomitant
Interacting
Renal Failure Acute Hospitalization 10/9/2008 65 Female 7/31/2009 Physician Germany
Primary
Secondary
Concomitant
Somnolence 6/30/2009 Female 8/11/2009 Pharmacist United States
Primary
Concomitant
Death Death 8/29/2009 Physician United States
Primary
Secondary
Syncope Other Serious 1/1/2008 Female 8/27/2009 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Death 1/1/2007 58 Female 9/3/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 45 Male 9/14/2009 Consumer United States
Primary
Secondary
Concomitant
Vulvovaginal Mycotic Infection Other Serious 4/1/2002 42 Female 232 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 4/1/1999 28 Female 226 lb 9/23/2009 United States
Primary
Concomitant
Vertigo Other Serious 2/19/2009 Male 185 lb 10/1/2009
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2008 Female 10/2/2009 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 6/12/2009 Male 10/7/2009 United States
Primary
Concomitant
Somnambulism Hospitalization 6/25/2009 Male 168 lb 10/12/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 45 Male 10/15/2009 Consumer United States
Primary
Secondary
Concomitant
Vertigo Other Serious 2/19/2009 Male 185 lb 10/16/2009
Primary
Secondary
Concomitant
Weight Decreased Other Serious 45 Male 10/22/2009 Consumer United States
Primary
Secondary
Concomitant
Somnambulism Hospitalization 6/1/2009 Male 168 lb 10/26/2009 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 3/1/2006 Male 260 lb 10/26/2009 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 6/12/2009 Male 11/3/2009 United States
Primary
Concomitant
Ataxia Hospitalization 3/31/2009 Male 11/27/2009 Physician United States
Primary
Concomitant
Hypotension Hospitalization 1/31/2009 Male 180 lb 11/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 6/1/2009 38 Male 159 lb 12/9/2009 Physician United States
Primary
Secondary
Concomitant
Pain Hospitalization 10/1/2009 43 Female 152 lb 12/16/2009 Consumer United States
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 59 Female 12/11/2009 United States
Primary
Concomitant
Malaise Other Serious 40 Male 12/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Product Quality Issue 11/1/2009 Male 12/21/2009 Pharmacist United States
Primary
Concomitant
Neck Pain Hospitalization 3/31/2009 Male 12/30/2009 Physician United States
Primary
Concomitant
Respiratory Arrest Hospitalization 45 Female 1/8/2010 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 63 Male 1/15/2010 Physician United States
Primary
Secondary
Poisoning Death 45 Female 3/9/2010 Physician United States
Primary
Secondary
Urinary Retention Hospitalization 3/3/2010 64 Male 132 lb 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2000 Female 140 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Dysgeusia 8/12/2009 83 Male 200 lb 4/21/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 4/22/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 4/28/2010 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2007 42 Female 4/30/2010 Physician United States
Primary
Concomitant
Muscle Injury Other Serious 2/17/2010 54 Female 4/30/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/3/2010 United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 4/15/2010 67 Male 5/13/2010 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/21/2010 United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 5/14/2008 65 Female 183 lb 5/28/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 6/2/2010 United States
Primary
Concomitant
Stress Other Serious 4/27/2010 83 Female 108 lb 6/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Fluid Retention Life Threatening 4/1/2010 53 Female 6/4/2010 Physician United States
Primary
Concomitant
Drug Ineffective 1/1/2010 60 Male 189 lb 6/9/2010 Other Health Professional United States
Primary
Concomitant
Surgery Other Serious 10/1/2009 53 Male 186 lb 6/14/2010 Consumer United States
Primary
Concomitant
Interacting
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 6/15/2010 United States
Primary
Concomitant
Respiratory Depression Death 6/16/2010 28 Male 403 lb 6/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 5/20/2010 66 Male 159 lb 6/18/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/2006 50 Female 6/18/2010 United States
Primary
Concomitant
Vomiting Other Serious 6/5/2005 53 Male 174 lb 6/25/2010 Physician United States
Primary
Concomitant
Psychotic Disorder Other Serious 7/7/2008 64 Female 150 lb 7/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nervousness 12/3/2008 37 Female 130 lb 7/23/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 49 Female 313 lb 8/13/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 49 Female 234 lb 9/14/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1991 54 Male 188 lb 9/30/2010 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 5/22/2010 63 Female 10/7/2010 United States
Primary
Concomitant
Weight Increased Other Serious 3/14/2006 50 Female 10/8/2010 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/9/2008 65 Female 141 lb 11/22/2010 Physician Germany
Primary
Secondary
Concomitant
Interacting
Yellow Skin Other Serious 1/1/2008 54 Female 11/25/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/9/2008 65 Female 141 lb 12/2/2010 Germany
Primary
Secondary
Concomitant
Interacting
Rash 12/13/2010 Consumer United States
Primary
Concomitant
Death Death 11/27/2010 77 Female 12/15/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/22/2010 63 Female 12/16/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 60 Male 12/28/2010 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 12/31/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 59 Male 12/17/2010 United States
Primary
Concomitant
Death Death 1/1/2009 20 Female 1/7/2011 Physician United States
Primary
Secondary
Tremor Hospitalization 3/14/2006 50 Female 1/7/2011 Physician United States
Primary
Concomitant
Death Death 1/1/2009 30 Female 1/10/2011 Physician United States
Primary
Secondary
Diabetic Complication Hospitalization 1/1/2010 48 Female 132 lb 1/11/2011 Other Health Professional United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 10/26/2010 44 Female 212 lb 1/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Administration Error 11/1/2010 49 Male 226 lb 1/10/2011 Consumer United States
Primary
Concomitant
Death Death 20 Female 1/20/2011 Physician United States
Primary
Secondary
Death Death 20 Female 1/21/2011 Physician United States
Primary
Secondary
Unresponsive To Stimuli Hospitalization 9/11/2010 47 Female 1/24/2011 Other Health Professional United States
Primary
Secondary
Death Death 20 Female 1/20/2011 United States
Primary
Secondary
Death Death 20 Female 2/11/2011 Physician United States
Primary
Secondary
Substance Abuse Death 11/16/2008 27 Male 220 lb 2/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 20 Female 2/5/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 30 Female 2/24/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 3/7/2008 50 Male 3/1/2011 Physician Canada
Primary
Secondary
Dehydration Hospitalization 10/9/2008 65 Female 141 lb 3/3/2011 Physician Germany
Primary
Secondary
Concomitant
Interacting
Cardio-respiratory Arrest Death 30 Female 3/4/2011 Other Health Professional United States
Primary
Secondary
Multiple Myeloma Death 11/27/2010 77 Female 3/4/2011 Physician United States
Primary
Concomitant
Blood Glucose Increased Other Serious 2/1/2011 53 Male 210 lb 3/8/2011 Consumer United States
Primary
Concomitant
Seroma Other Serious 1/1/2000 52 Female 140 lb 3/10/2011 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death Female 237 lb 3/11/2011 Other Health Professional United States
Primary
Concomitant
Toxicity To Various Agents Death 3/7/2008 50 Male 3/21/2011 Physician Canada
Primary
Secondary
Death Death Male 3/22/2011 Consumer United States
Primary
Concomitant
Intentional Overdose Other Serious 4/1/2008 36 Male 3/29/2011 Lawyer United States
Primary
Concomitant
Abdominal Discomfort Other Serious 5/22/2010 63 Female 3/31/2011 Consumer United States
Primary
Concomitant
Pain In Jaw Death 1/1/2007 76 Female 166 lb 3/31/2011 United States
Primary
Concomitant
Substance Abuse Death 11/16/2008 27 Male 220 lb 4/1/2011 Lawyer United States
Primary
Secondary
Concomitant
Gallbladder Cholesterolosis Other Serious 4/1/2009 28 Female 242 lb 4/5/2011 Pharmacist United States
Primary
Secondary
Concomitant
Cholelithiasis Other Serious 4/1/2009 28 Female 242 lb 4/5/2011 Pharmacist United States
Primary
Secondary
Concomitant
Influenza Hospitalization 3/19/2011 39 Male 4/8/2011 Other Health Professional Canada
Primary
Concomitant
Iliac Artery Thrombosis Other Serious 1/1/2000 52 Female 140 lb 4/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 10/18/2000 61 Male 4/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 1/1/2000 52 Female 140 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Radicular Pain Hospitalization 1/1/2004 38 Female 4/26/2011 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/24/2010 43 Female 205 lb 5/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Dysarthria Disability 1/1/2002 41 Male 185 lb 5/24/2011 Consumer United States
Primary
Concomitant
Aggression Hospitalization 1/1/2007 66 Male 7/29/2011 Lawyer United States
Primary
Concomitant
Confusional State Other Serious 8/25/2011 37 Male 9/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective 9/6/2011 57 Male 10/3/2011 Pharmacist United States
Primary
Concomitant
Toxicity To Various Agents Death 50 Male 11/4/2011 Other Health Professional Canada
Primary
Secondary
Oedema Peripheral Hospitalization 10/9/2008 65 Female 1/27/2012 Consumer Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/9/2008 65 Female 141 lb 1/30/2012 Physician Germany
Primary
Secondary
Concomitant
Interacting
Drug Interaction Hospitalization 10/9/2008 65 Female 2/8/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Anxiety Hospitalization 5/1/2007 45 Female 2/9/2012 Lawyer United States
Primary
Concomitant
Poisoning Death 1/1/2010 45 Male 3/12/2012 Physician Finland
Primary
Concomitant
Blood Glucose Increased Other Serious 3/11/2012 76 Female 130 lb 3/16/2012 Consumer United States
Primary
Concomitant
Abnormal Dreams 1/1/2012 41 Male 3/19/2012 Other Health Professional United States
Primary
Concomitant
Poisoning Death 1/1/2010 45 Male 3/20/2012 Physician Finland
Primary
Concomitant
Poisoning Death 1/1/2010 45 Male 3/27/2012 Physician Finland
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious Male 4/3/2012 Consumer United States
Primary
Concomitant
Abnormal Dreams 1/1/2012 41 Male 4/5/2012 Other Health Professional United States
Primary
Concomitant
Hyperkalaemia Life Threatening 4/26/2012 52 Female 196 lb 5/17/2012 Other Health Professional United Kingdom
Primary
Concomitant
Sleep Disorder Other Serious Male 5/24/2012 Physician United States
Primary
Concomitant
Anxiety Other Serious 3/20/2009 45 Male 6/25/2012 Lawyer United States
Primary
Concomitant
Parkinson's Disease Other Serious Female 174 lb 9/17/2012 Lawyer Us
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/2/2011 51 Female 214 lb 10/18/2012 Physician De
Primary
Concomitant
Spinal Disorder Other Serious 39 Male 10/12/2012 Consumer Us
Primary
Concomitant
Diarrhoea Hospitalization 6/15/2012 68 Female 170 lb 10/4/2012 Physician Us
Primary
Secondary
Concomitant
Rash Hospitalization Female 8/31/2012 Pharmacist Us
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 46 Female 9/11/2012 Other Health Professional Us
Primary
Secondary
Overdose Hospitalization 46 Female 9/17/2012 Other Health Professional Us
Primary
Secondary
Rash Erythematous 6/2012 Male 205 lb 9/18/2012 Consumer Us
Primary
Secondary
Concomitant
Overdose Life Threatening 46 Female 9/20/2012 Other Health Professional Us
Primary
Secondary
Unresponsive To Stimuli Hospitalization 46 Female 9/19/2012 Other Health Professional Us
Primary
Secondary
Lung Disorder Other Serious 52 Male 10/16/2012 Physician Us
Primary
Concomitant
Urinary Tract Infection Other Serious 2003 Female 10/10/2012 Consumer Us
Primary
Concomitant

Drug Data