Amitriptyline combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Troponin Increased Hospitalization 55 Female 3/15/2006 Pharmacist United States
Primary
Secondary
Vomiting Hospitalization 9/8/2004 Female 3/28/2006 Physician Germany
Primary
Concomitant
No Adverse Effect Hospitalization 1/1/2006 Male 201 lb 4/6/2006 Physician United States
Primary
Secondary
Concomitant
Infected Skin Ulcer Hospitalization 8/8/2008 12/14/2008 Physician Brazil
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 1/1/2008 75 Male 213 lb 2/12/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Male 220 lb 2/19/2009 Physician United States
Primary
Concomitant
Flushing Female 2/24/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 3/1/2006 Male 260 lb 3/5/2009 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2001 36 Female 226 lb 3/6/2009 Consumer United States
Primary
Concomitant
Polymyalgia Rheumatica Other Serious 7/29/2006 Female 166 lb 3/5/2009 Physician United States
Primary
Concomitant
Ventricular Fibrillation Death 3/11/2009 Female 229 lb 3/13/2009 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/11/2002 Female 198 lb 3/27/2009 Physician Spain
Primary
Concomitant
Weight Increased Hospitalization 2/28/2006 44 Female 7/1/2009 Consumer United States
Primary
Secondary
Concomitant
Hypoaesthesia Facial Hospitalization 3/3/2009 63 7/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Crohn's Disease Hospitalization 4/23/2009 53 Female 7/7/2009 Other Health Professional Canada
Primary
Concomitant
Renal Failure Acute Life Threatening 6/8/2009 Female 7/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Death 83 Female 8/3/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2009 59 Male 231 lb 8/12/2009 Physician United Kingdom
Primary
Concomitant
Social Problem Hospitalization 1/20/2006 73 Male 163 lb 8/10/2009 United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 10/3/2006 65 Male 213 lb 8/20/2009 Other Health Professional United States
Primary
Concomitant
Skin Burning Sensation Female 8/21/2009 United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Female 8/21/2009 United States
Primary
Concomitant
Pruritus 9/1/2008 Female 185 lb 8/21/2009 United States
Primary
Concomitant
Paraesthesia 10/29/2008 Female 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation Female 8/22/2009 United States
Primary
Concomitant
Speech Disorder Disability 53 8/28/2009 Consumer Canada
Primary
Concomitant
Nocturia Other Serious 8/19/2009 56 9/9/2009 Consumer Brazil
Primary
Concomitant
Weight Decreased Hospitalization 11/1/2008 Female 290 lb 9/24/2009 Consumer United States
Primary
Concomitant
Presyncope Other Serious 61 Female 230 lb 10/2/2009 United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 10/3/2006 65 Male 213 lb 10/2/2009 Other Health Professional United States
Primary
Concomitant
Pustular Psoriasis Other Serious 4/1/2009 Female 198 lb 10/5/2009 Physician United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/20/2004 46 Male 234 lb 10/5/2009 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 10/3/2006 65 Male 213 lb 10/7/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 5/1/2002 56 10/9/2009 Consumer Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2008 52 Female 10/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/13/2008 52 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Ulcer Life Threatening 2/4/2006 Female 10/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 10/22/2009 United States
Primary
Concomitant
Weight Increased Other Serious 5/1/2002 56 Male 216 lb 11/3/2009 Physician Brazil
Primary
Secondary
Concomitant
Vomiting Other Serious 10/8/2008 Female 238 lb 11/5/2009 United States
Primary
Concomitant
Radius Fracture Other Serious 8/9/2006 Female 11/9/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Speech Disorder Disability 53 Female 11/24/2009 Consumer Canada
Primary
Concomitant
Skin Burning Sensation 10/28/2009 Female 190 lb 11/25/2009 Consumer United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/1/2008 51 Female 12/29/2009 Other Health Professional United States
Primary
Concomitant
Hypertension Other Serious 64 Female 150 lb 12/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Disorder Hospitalization 10/1/2009 59 Female 198 lb 1/1/2010 Other Health Professional United States
Primary
Concomitant
Chromaturia Other Serious 80 Female 2/21/2010 Physician United States
Primary
Concomitant
Cystoscopy Other Serious 80 Female 3/18/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 5/1/2002 54 Male 216 lb 4/13/2010 Physician Brazil
Primary
Secondary
Concomitant
Dysgeusia 8/12/2009 83 Male 200 lb 4/21/2010 Consumer United States
Primary
Concomitant
Surgery Other Serious 1/13/2010 56 Female 160 lb 4/23/2010 Consumer United States
Primary
Secondary
Concomitant
Muscle Injury Other Serious 2/17/2010 54 Female 4/30/2010 Consumer United States
Primary
Concomitant
Cystoscopy Other Serious 80 Female 5/4/2010 Physician United States
Primary
Concomitant
Nausea Other Serious 3/1/2010 36 Female 247 lb 5/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Other Serious 1/13/2010 56 Female 160 lb 6/4/2010 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/7/2010 Other Health Professional Israel
Primary
Secondary
Concomitant
Tooth Erosion Hospitalization 1/1/2009 71 Male 240 lb 5/5/2010 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Female 6/10/2010 Other Health Professional Israel
Primary
Secondary
Dermatitis Exfoliative Hospitalization 2/12/2010 76 Male 198 lb 6/10/2010 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious Female 247 lb 6/11/2010 Physician United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 63 Female 6/14/2010 Physician Canada
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Female 6/21/2010 Physician France
Primary
Secondary
Haemorrhage Intracranial Hospitalization 48 Male 6/22/2010 Physician United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious 11/1/2009 57 Female 154 lb 6/22/2010 Physician United States
Primary
Concomitant
Autoimmune Thrombocytopenia Other Serious 1/1/2009 53 Female 366 lb 6/23/2010 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 70 Female 6/23/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Injury Hospitalization 1/1/2006 38 Female 260 lb 6/23/2010 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 65 Male 7/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 65 Male 7/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Female 239 lb 7/19/2010 Consumer United States
Primary
Concomitant
Weight Increased 6/1/2009 49 Male 240 lb 8/4/2010 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 5/14/2007 58 Female 8/19/2010 Lawyer United States
Primary
Concomitant
Joint Injury Other Serious 1/1/2009 54 Male 205 lb 8/20/2010 Consumer United States
Primary
Concomitant
Nausea 8/26/2010 63 Female 186 lb 9/7/2010 Consumer United States
Primary
Concomitant
Phobia Of Driving 1/21/2010 70 Female 225 lb 9/15/2010 Consumer United States
Primary
Concomitant
Speech Disorder Disability 53 Female 9/16/2010 Consumer Canada
Primary
Concomitant
Nausea Other Serious 3/1/2010 36 Female 247 lb 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 65 Male 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 60 Female 150 lb 9/20/2010 United States
Primary
Concomitant
Rash Vesicular Other Serious 6/1/2010 55 Female 9/23/2010 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious Female 9/28/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 4/7/2004 68 Female 133 lb 9/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 9/15/2010 59 Female 168 lb 10/1/2010 Other Health Professional United States
Primary
Concomitant
Arthropod Bite 10/1/2010 61 Female 222 lb 10/7/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 4/7/2004 68 Female 133 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 6/6/2005 56 Female 150 lb 10/14/2010 Physician United Kingdom
Primary
Concomitant
Suicidal Ideation Disability 8/11/2010 52 Male 252 lb 10/14/2010 Physician New Zealand
Primary
Secondary
Concomitant
Rash Vesicular Other Serious 6/1/2010 55 Female 11/8/2010 Other Health Professional United States
Primary
Concomitant
Death Other Serious 10/1/2010 56 Female 210 lb 11/14/2010 Consumer United States
Primary
Concomitant
Shock Hospitalization 10/25/2004 57 Female 125 lb 11/10/2010 Lawyer United States
Primary
Concomitant
Malaise Hospitalization 78 Female 155 lb 11/24/2010 Physician United States
Primary
Concomitant
Pituitary Tumour Removal Other Serious 57 Male 11/25/2010 Consumer Germany
Primary
Concomitant
Coma Hospitalization 10/26/2010 77 Male 11/23/2010 Physician Canada
Primary
Concomitant
Cardiomyopathy Hospitalization 65 Male 216 lb 11/29/2010 Other Health Professional United States
Primary
Concomitant
Stomatitis Other Serious Female 11/29/2010 Consumer Canada
Primary
Secondary
Concomitant
Polyarthritis Hospitalization 10/29/2010 54 Female 177 lb 11/29/2010 Physician Chile
Primary
Secondary
Concomitant
Visual Impairment Other Serious 12/1/2009 58 Male 245 lb 11/28/2010 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 9/28/2005 74 Female 11/11/2010 United States
Primary
Concomitant
Vomiting Other Serious 6/1/2010 47 Female 187 lb 12/3/2010 Other Health Professional Netherlands
Primary
Concomitant
Myalgia Other Serious 53 Female 10/28/2010 Physician Canada
Primary
Concomitant
Stomatitis Other Serious Female 12/7/2010 Physician Canada
Primary
Secondary
Concomitant
Insomnia 5/11/2010 70 Female 10/25/2010 Consumer United States
Primary
Concomitant
Speech Disorder Other Serious Female 12/8/2010 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 10/30/2008 77 Male 234 lb 12/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rash 12/13/2010 Consumer United States
Primary
Concomitant
Speech Disorder Disability 53 Female 11/24/2009 Consumer Canada
Primary
Concomitant
Nausea Other Serious 3/1/2010 36 Female 247 lb 5/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 65 Male 7/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Hospitalization 78 Female 155 lb 12/22/2010 Physician United States
Primary
Concomitant
Paralysis Other Serious 10/26/2010 77 Male 207 lb 12/27/2010 Physician Canada
Primary
Concomitant
Abasia 69 Male 1/7/2011 Consumer United States
Primary
Concomitant
Medication Residue 60 Female 1/7/2011 Physician United States
Primary
Concomitant
Back Pain Hospitalization 78 Female 155 lb 1/10/2011 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/1/2010 73 Female 1/13/2011 Physician United States
Primary
Concomitant
Atrioventricular Block Hospitalization 12/3/2009 65 Male 229 lb 1/14/2011 Physician Brazil
Primary
Concomitant
Atrioventricular Block Hospitalization 12/3/2009 65 Male 229 lb 1/19/2011 Other Health Professional Brazil
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2002 34 Female 205 lb 1/20/2011 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 43 Female 238 lb 1/20/2011 Physician United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 12/23/2010 71 Female 1/20/2011 Physician New Zealand
Primary
Secondary
Concomitant
Atrioventricular Block Hospitalization 12/3/2009 65 Male 229 lb 1/28/2011 Physician Brazil
Primary
Concomitant
Atrioventricular Block Hospitalization 12/3/2009 65 Male 229 lb 2/17/2011 Physician Brazil
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/26/2008 68 Female 2/21/2011 Consumer Canada
Primary
Concomitant
Left Atrial Dilatation Hospitalization 83 Female 2/4/2011 Lawyer United States
Primary
Concomitant
Pain Hospitalization 6/26/2008 68 Female 3/3/2011 Consumer Canada
Primary
Concomitant
Myocardial Infarction Hospitalization 41 Male 224 lb 3/3/2011 Consumer United States
Primary
Concomitant
Respiratory Distress Hospitalization Female 148 lb 2/25/2011 Physician United States
Primary
Concomitant
Death Death 1/17/2011 41 Male 3/4/2011 Physician South Africa
Primary
Secondary
Concomitant
Drug Ineffective 52 Female 3/1/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 2/20/2011 79 Female 148 lb 3/9/2011 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/19/2010 56 3/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Generalised Erythema Hospitalization 61 Male 273 lb 3/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Akathisia Other Serious 1/1/1984 32 Female 115 lb 2/28/2011 Lawyer United States
Primary
Concomitant
Chest Pain Other Serious Female 3/21/2011 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/9/2010 65 Female 159 lb 3/21/2011 Consumer United States
Primary
Secondary
Concomitant
Dysuria Hospitalization 5/1/2002 54 Male 220 lb 3/22/2011 Physician Brazil
Primary
Secondary
Concomitant
Coronary Artery Occlusion Life Threatening Female 122 lb 3/23/2011 Consumer United States
Primary
Secondary
Renal Failure Acute Hospitalization 12/5/2010 51 Female 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Other Serious 67 Female 196 lb 4/6/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Hypertension Hospitalization 53 Female 145 lb 4/6/2011 Physician United States
Primary
Concomitant
Thrombosis Other Serious 1/26/2011 63 Male 187 lb 4/14/2011 Physician United Kingdom
Primary
Concomitant
Cerebrovascular Disorder Hospitalization 89 Female 117 lb 4/14/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Blood Test Abnormal Hospitalization 89 Female 117 lb 4/14/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Stress Other Serious 7/6/2007 75 Male 145 lb 4/19/2011 Lawyer United States
Primary
Concomitant
Paraesthesia Hospitalization 6/1/2010 62 Male 170 lb 4/20/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 9/15/2007 60 Female 190 lb 4/26/2011 Other Health Professional United States
Primary
Concomitant
Hypoaesthesia Hospitalization 1/26/2011 63 Male 187 lb 4/27/2011 Physician United Kingdom
Primary
Concomitant
Nasopharyngitis Hospitalization 6/26/2008 68 Female 4/28/2011 Consumer Canada
Primary
Concomitant
Oedema Peripheral Other Serious 12/19/2010 56 6/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 9/22/2007 42 Female 7/28/2011 Lawyer United States
Primary
Concomitant
Suicidal Ideation Other Serious 6/1/2011 51 Female 154 lb 8/2/2011 Physician Colombia
Primary
Concomitant

Drug Data