Amitriptyline combined with Lorazepam

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Dysgeusia 10/19/2005 52 Female 249 lb 1/5/2006 Consumer United States
Primary
Concomitant
Drug Tolerance Increased Other Serious Female 162 lb 3/14/2006 Other Health Professional United States
Primary
Concomitant
Schizophrenia Life Threatening 8/3/2005 Male 222 lb 3/31/2006 Physician United States
Primary
Secondary
Concomitant
Blast Cell Proliferation Hospitalization 9/29/2008 25 Male 157 lb 12/29/2008 Other Health Professional United States
Primary
Concomitant
Wound Secretion Hospitalization 9/1/2008 Female 12/23/2008 Physician United States
Primary
Concomitant
Psychotic Disorder Other Serious 7/7/2008 Female 150 lb 2/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/1/2006 51 Male 119 lb 3/2/2009 Physician United States
Primary
Concomitant
Muscular Weakness Hospitalization 1/1/2006 74 Male 3/20/2009 Consumer Canada
Primary
Concomitant
Pneumonia Death 78 Female 3/23/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 5/15/2005 36 Female 167 lb 4/7/2009 United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 7/1/2000 Female 6/19/2009 Lawyer United States
Primary
Secondary
Concomitant
Crohn's Disease Hospitalization 4/23/2009 53 Female 7/7/2009 Other Health Professional Canada
Primary
Concomitant
Pancreatitis Relapsing Other Serious 11/11/2004 46 Male 140 lb 7/8/2009 United States
Primary
Concomitant
Wheezing Other Serious 9/1/2006 Female 7/13/2009 Physician United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2002 52 Female 140 lb 7/16/2009 United States
Primary
Concomitant
Restlessness Other Serious 50 Female 110 lb 7/17/2009 United States
Primary
Concomitant
Pancreatitis Relapsing Other Serious 11/11/2004 46 Male 140 lb 7/17/2009 United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 63 Female 8/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 63 Female 8/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diabetic Neuropathy Other Serious 5/9/2006 49 Female 210 lb 8/13/2009 United States
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization Female 8/18/2009 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 63 Female 8/20/2009
Primary
Secondary
Linear Iga Disease Hospitalization 68 Female 8/19/2009 Belgium
Primary
Concomitant
Skin Erosion Other Serious 68 Female 8/21/2009 Other Health Professional Belgium
Primary
Concomitant
Poor Venous Access Other Serious 8/4/2009 Female 130 lb 8/21/2009 Canada
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 63 Female 8/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Speech Disorder Disability 53 8/28/2009 Consumer Canada
Primary
Concomitant
Vasculitis Hospitalization 68 Male 8/31/2009 Physician Belgium
Primary
Concomitant
Pancreatitis Relapsing Other Serious 11/11/2004 46 Male 9/2/2009 United States
Primary
Concomitant
Death Death 48 Female 9/7/2009 Physician United States
Primary
Secondary
Sleep Apnoea Syndrome Other Serious 63 Female 9/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 56 Male 9/8/2009 Physician United States
Primary
Secondary
Vasculitis Hospitalization 68 Female 9/16/2009 Other Health Professional Belgium
Primary
Concomitant
Linear Iga Disease Hospitalization 68 Female 9/14/2009 Belgium
Primary
Concomitant
Urinary Tract Infection 5/25/2001 35 Female 100 lb 9/23/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2005 34 Female 249 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 45 Female 256 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 4/1/1999 28 Female 226 lb 9/23/2009 United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 12/8/2002 33 Female 172 lb 9/23/2009 United States
Primary
Concomitant
Uterine Leiomyoma 1/1/2000 40 Female 9/23/2009 United States
Primary
Concomitant
Drug Ineffective 9/17/2009 Female 9/28/2009 Consumer
Primary
Concomitant
Tremor Hospitalization 1/1/2005 38 Female 9/30/2009 United States
Primary
Secondary
Concomitant
Rash 8/9/2009 56 Female 9/24/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 35 Female 235 lb 10/14/2009 United States
Primary
Concomitant
Lactic Acidosis Death 43 10/22/2009 Other Health Professional Italy
Primary
Interacting
Multi-organ Failure Other Serious 11/2/2007 43 Male 139 lb 10/28/2009 Other Health Professional Italy
Primary
Concomitant
Interacting
Hospitalisation Hospitalization Female 11/2/2009 Canada
Primary
Concomitant
Hospitalisation Hospitalization Female 11/6/2009 Canada
Primary
Concomitant
Vision Blurred Other Serious 2/14/2003 Female 195 lb 11/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 5/26/2009 63 Female 10/20/2009 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Disability 53 Female 11/24/2009 Consumer Canada
Primary
Concomitant
Ataxia Hospitalization 3/31/2009 Male 11/27/2009 Physician United States
Primary
Concomitant
Macular Degeneration Hospitalization 1/1/2004 Female 11/30/2009 Consumer United States
Primary
Concomitant
Venous Insufficiency Hospitalization 9/1/2008 Female 12/1/2009 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2002 Male 12/1/2009 Physician United States
Primary
Concomitant
Sensation Of Heaviness Other Serious 7/12/2009 Female 128 lb 12/17/2009 Brazil
Primary
Concomitant
Visual Impairment Hospitalization 59 Female 12/11/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/11/2004 46 Male 12/18/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2002 Female 195 lb 12/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neck Pain Hospitalization 3/31/2009 Male 12/30/2009 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2002 Female 195 lb 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 48 Female 3/9/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Septal Defect Hospitalization 12/23/2006 25 Female 115 lb 3/16/2010 United States
Primary
Concomitant
Death Death 1/1/2008 33 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Weight Increased Other Serious 1/1/2002 Female 195 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 3/1/2010 62 Female 161 lb 4/12/2010 Consumer United States
Primary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 4/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 4/22/2010 United States
Primary
Concomitant
Surgery Other Serious 1/13/2010 56 Female 160 lb 4/23/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 4/28/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/3/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/21/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 6/2/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 71 Female 79 lb 5/26/2010 Consumer United States
Primary
Concomitant
Surgery Other Serious 1/13/2010 56 Female 160 lb 6/4/2010 Physician United States
Primary
Secondary
Concomitant
Vascular Insufficiency Other Serious 10/1/2007 77 Female 6/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 3/12/2010 62 Female 161 lb 6/14/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 6/15/2010 United States
Primary
Concomitant
Wheelchair User Other Serious 10/9/2001 65 Female 169 lb 6/15/2010 United States
Primary
Secondary
Concomitant
Suicidal Ideation Life Threatening 1/1/2008 40 Female 190 lb 6/17/2010 Consumer
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/2006 50 Female 6/18/2010 United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/16/2010 71 Male 6/21/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 6/22/2010 Lawyer United States
Primary
Concomitant
Colitis Hospitalization 2/15/2010 56 Female 198 lb 6/22/2010 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 3/14/2006 50 Female 6/25/2010 United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 4/10/2010 72 Female 6/21/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 41 Female 6/28/2010 Physician Germany
Primary
Secondary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 7/5/2010 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/16/2010 71 Male 7/5/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 1/2/2002 34 Female 190 lb 7/9/2010 United States
Primary
Concomitant
Psychotic Disorder Other Serious 7/7/2008 64 Female 150 lb 7/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 8/18/2010 62 Male 171 lb 8/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 1/1/2008 40 Female 190 lb 9/14/2010 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Disability 53 Female 9/16/2010 Consumer Canada
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 8/18/2010 62 Male 171 lb 9/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Infection Hospitalization 9/6/2010 46 Male 9/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/9/2001 65 Female 169 lb 9/30/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/14/2006 50 Female 10/8/2010 United States
Primary
Concomitant
Paraesthesia Disability 8/21/2010 54 Female 10/14/2010 Consumer United States
Primary
Concomitant
Benign Ovarian Tumour Hospitalization 8/6/2010 58 Female 165 lb 10/15/2010 Other Health Professional Canada
Primary
Concomitant
Presyncope 10/1/2010 71 Female 152 lb 11/4/2010 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 7/1/2010 53 Female 11/4/2010 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 7/1/2010 11/27/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 9/28/2005 74 Female 11/11/2010 United States
Primary
Concomitant
Anosmia 72 Female 157 lb 12/8/2010 Consumer United States
Primary
Secondary
Weight Decreased Hospitalization 6/1/2010 48 Female 12/9/2010 Consumer United States
Primary
Concomitant
Hypersensitivity Other Serious 1/12/2010 43 Female 196 lb 12/13/2010 Consumer United States
Primary
Concomitant
Intentional Drug Misuse Hospitalization 6/1/2008 61 Female 195 lb 12/14/2010 United States
Primary
Concomitant
Respiratory Failure Other Serious 65 Female 12/14/2010 Consumer United States
Primary
Concomitant
Speech Disorder Disability 53 Female 11/24/2009 Consumer Canada
Primary
Concomitant
Macular Degeneration 10/1/2009 12/20/2010 Physician United States
Primary
Concomitant
Breast Cancer Other Serious Female 12/16/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 3/14/2006 50 Female 12/30/2010 United States
Primary
Concomitant
Lung Infection Hospitalization 9/6/2010 1/7/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 3/14/2006 50 Female 1/7/2011 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 7/1/2010 53 Female 1/24/2011 Physician United States
Primary
Secondary
Concomitant
Anaemia Other Serious 10/9/2001 65 Female 169 lb 1/27/2011 Lawyer United States
Primary
Secondary
Concomitant
Blood Glucose Increased Female 210 lb 2/16/2011 Consumer United States
Primary
Concomitant
Stress Hospitalization 1/1/2010 58 Female 180 lb 2/16/2011 Consumer United States
Primary
Concomitant
Burning Sensation Disability 8/21/2010 54 Female 2/17/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Calcium Increased Other Serious Female 2/22/2011 Physician United States
Primary
Concomitant
Status Epilepticus Hospitalization 74 Female 3/10/2011 Other Health Professional Italy
Primary
Concomitant
Pancytopenia Other Serious 2/5/2011 59 Female 110 lb 3/10/2011 Consumer Portugal
Primary
Concomitant
Blood Pressure Inadequately Controlled Other Serious 1/14/2008 54 Male 248 lb 3/15/2011 Lawyer United States
Primary
Concomitant
Abdominal Discomfort Death 6/18/2010 54 Male 105 lb 3/3/2011 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 12/28/2010 74 Male 170 lb 3/24/2011 Consumer United States
Primary
Concomitant
Dyspepsia Other Serious 12/1/2005 39 Female 144 lb 3/28/2011 United States
Primary
Secondary
Concomitant
Central Nervous System Lesion Other Serious 74 Female 3/22/2011 Italy
Primary
Concomitant
Pneumonia Hospitalization 12/29/2010 60 Female 115 lb 4/8/2011 Physician United States
Primary
Secondary
Concomitant
Haematological Malignancy Death 65 Female 4/8/2011 Other Health Professional United States
Primary
Concomitant
Pelvic Pain Other Serious 1/1/2010 58 Male 137 lb 4/11/2011 Physician Canada
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 41 Female 4/11/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Injury Hospitalization 5/10/2008 60 Female 4/14/2011 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Death 5/17/2010 65 Female 4/14/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 56 Male 216 lb 4/18/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Hospitalization 12/15/2005 56 Male 146 lb 4/18/2011 Consumer United States
Primary
Concomitant
Dermatitis Other Serious 2/5/2011 59 Female 110 lb 4/15/2011 Physician Portugal
Primary
Concomitant
Incontinence Hospitalization 8/1/2009 63 Female 4/25/2011 Physician United States
Primary
Concomitant
Postoperative Wound Infection Other Serious 1/1/2009 55 Female 198 lb 4/27/2011 Physician United Kingdom
Primary
Concomitant
Off Label Use Hospitalization 7/1/2007 62 Male 220 lb 5/6/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 12/29/2010 60 Female 115 lb 5/9/2011 Physician United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 1/1/2009 50 Female 163 lb 6/30/2011 Consumer United States
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 7/11/2011 76 Female 8/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 6/24/2007 62 Male 209 lb 11/8/2011 Lawyer United States
Primary
Concomitant
Intentional Drug Misuse Death 31 Male 191 lb 12/27/2011 Consumer United States
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 8/18/2010 62 Male 171 lb 1/31/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Quadriplegia Other Serious Male 2/2/2012 Consumer United States
Primary
Concomitant
Nausea Female 115 lb 5/7/2012 Consumer United States
Primary
Concomitant
Vulvovaginal Pain Other Serious 2003 Female 12/7/2012 Consumer Us
Primary
Concomitant
Toxicity To Various Agents Death 9/26/2008 36 Female 8/29/2012 Physician Us
Primary
Secondary
Concomitant