Amitriptyline combined with Levothyroxine Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence 10/1/2005 87 Male 134 lb 1/5/2006 Consumer United States
Primary
Concomitant
Weight Decreased 10/25/2005 60 Female 197 lb 1/20/2006 Consumer United States
Primary
Concomitant
Arthralgia Other Serious 50 Female 173 lb 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 10/10/2003 Female 121 lb 12/23/2008 Consumer United Kingdom
Primary
Concomitant
Pancreatitis Acute Other Serious 1/1/2008 75 Male 213 lb 2/12/2009 Physician United Kingdom
Primary
Concomitant
Ototoxicity Hospitalization 10/10/2007 74 Female 146 lb 2/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Heart Rate Increased 12/15/2008 Female 2/24/2009 United States
Primary
Concomitant
Ototoxicity Hospitalization 10/10/2007 74 Female 146 lb 2/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/2/2009 80 Female 3/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/8/2008 Female 212 lb 3/4/2009 United States
Primary
Concomitant
Lower Limb Fracture Other Serious 6/1/2006 38 Female 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/1/2007 Female 108 lb 3/12/2009 Physician United States
Primary
Concomitant
Diverticulitis Other Serious 1/7/2009 Female 231 lb 3/13/2009 Consumer United Kingdom
Primary
Concomitant
Tremor Other Serious Female 3/24/2009 Consumer United States
Primary
Concomitant
Abdominal Pain 2/18/2009 83 Female 110 lb 4/1/2009 Consumer United States
Primary
Concomitant
Autoimmune Thrombocytopenia Other Serious 2/6/2007 Female 172 lb 4/27/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 9/1/2008 Male 213 lb 4/29/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 12/1/2007 Female 7/1/2009 United States
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 4/1/2009 Female 198 lb 7/14/2009 Physician United Kingdom
Primary
Concomitant
Pustular Psoriasis Other Serious 4/1/2009 Female 198 lb 7/15/2009 Physician United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Death 6/15/2008 Female 8/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vision Blurred 5/15/2009 50 Female 7/22/2009 Other Health Professional United States
Primary
Concomitant
Headache 9/24/2008 Female 8/22/2009 United States
Primary
Concomitant
Flushing Male 8/22/2009 United States
Primary
Concomitant
Syncope Other Serious 1/1/2008 Female 8/27/2009 Physician United States
Primary
Concomitant
Tremor Other Serious 4/24/2008 52 Male 8/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 12/22/2008 84 Female 128 lb 9/8/2009 Consumer United Kingdom
Primary
Concomitant
White Blood Cells Urine Positive 7/7/2008 Female 175 lb 9/12/2009 Other Health Professional United States
Primary
Concomitant
Vasculitis Hospitalization 1/1/2000 Female 9/18/2009 Physician France
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/4/2005 48 Female 245 lb 9/21/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 80 Female 9/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Interacting
Weight Decreased Other Serious 80 Female 9/22/2009 United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Death 1/1/2007 58 Female 9/29/2009 Other Health Professional United States
Primary
Concomitant
Presyncope Other Serious 61 Female 230 lb 10/2/2009 United States
Primary
Concomitant
Syncope Other Serious 1/1/2008 Female 10/2/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 80 Female 10/5/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Interacting
Pustular Psoriasis Other Serious 4/1/2009 Female 198 lb 10/5/2009 Physician United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious 7/1/2008 55 Female 174 lb 10/9/2009 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 7/1/2008 55 Female 174 lb 10/14/2009 Consumer United States
Primary
Concomitant
Pustular Psoriasis Other Serious 4/1/2009 Female 198 lb 10/15/2009 Physician United Kingdom
Primary
Concomitant
Skin Ulcer Life Threatening 2/4/2006 Female 10/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Arteriosclerosis Hospitalization 78 Female 10/23/2009 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 10/22/2009 United States
Primary
Concomitant
Death Death Female 11/2/2009 Other Health Professional United States
Primary
Concomitant
Self Injurious Behaviour Other Serious 49 Female 11/13/2009 Consumer United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 11/4/2009 65 Female 214 lb 11/17/2009 Physician Germany
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 58 Female 143 lb 12/2/2009 Other Health Professional United States
Primary
Concomitant
Surgery Hospitalization 1/1/2009 Female 12/3/2009 Other Health Professional Canada
Primary
Concomitant
Uveitis Disability 12/22/2007 Female 11/30/2009 Physician United States
Primary
Secondary
Concomitant
Poor Peripheral Circulation Hospitalization 5/9/2007 Female 12/1/2009 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 10/26/2009 49 Female 12/3/2009 Other Health Professional Denmark
Primary
Concomitant
Sepsis Death 6/15/2008 Female 12/9/2009 Consumer United Kingdom
Primary
Concomitant
Poor Quality Sleep Hospitalization 1/1/2009 54 Female 12/10/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 75 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/29/2009 Female 230 lb 12/15/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 75 Female 12/11/2009 United States
Primary
Concomitant
Suicidal Ideation Other Serious 49 Female 12/15/2009 Consumer Denmark
Primary
Concomitant
Weight Increased Other Serious 49 Female 12/30/2009 Consumer Denmark
Primary
Concomitant
Haemorrhoids Other Serious 1/1/2009 69 Female 137 lb 1/14/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious Female 1/14/2010 Consumer Germany
Primary
Concomitant
Sleep Disorder Other Serious 9/1/2008 Male 213 lb 2/18/2010 Consumer United States
Primary
Concomitant
Urinary Hesitation Other Serious 1/1/2008 Female 269 lb 3/31/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/19/2010 34 Female 217 lb 4/30/2010 Consumer United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 66 Female 234 lb 5/6/2010 United States
Primary
Concomitant
Treatment Failure Disability 2/24/2010 38 Female 213 lb 5/5/2010 Pharmacist United States
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 5/14/2008 65 Female 183 lb 5/28/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Stress Other Serious 4/27/2010 83 Female 108 lb 6/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 2/12/2010 83 Female 5/31/2010 Consumer United States
Primary
Concomitant
Thyroid Function Test Abnormal 1/1/2009 62 Female 172 lb 5/11/2010 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/25/2010 75 Female 174 lb 6/4/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 66 Female 234 lb 6/3/2010 United States
Primary
Concomitant
Weight Increased Other Serious 16 Female 6/9/2010 Consumer Czech Republic
Primary
Secondary
Renal Failure Acute Other Serious Female 247 lb 6/11/2010 Physician United Kingdom
Primary
Concomitant
Colitis Hospitalization 2/15/2010 56 Female 198 lb 6/22/2010 Physician United Kingdom
Primary
Concomitant
Tibia Fracture Hospitalization 6/4/2010 79 Male 6/22/2010 Consumer United States
Primary
Concomitant
Skin Lesion 10/26/2007 62 Female 157 lb 6/23/2010 Consumer United States
Primary
Concomitant
Ocular Hyperaemia 1/9/2009 64 Female 155 lb 6/24/2010 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 4/1/2010 68 Female 180 lb 6/25/2010 Consumer Canada
Primary
Concomitant
Syncope Other Serious 1/1/2008 54 Female 6/23/2010 Physician United States
Primary
Concomitant
Dystonia 8/1/2006 50 Female 125 lb 6/28/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased 1/1/2007 45 Female 231 lb 6/28/2010 Consumer United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 41 Female 6/28/2010 Physician Germany
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 64 Female 241 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Migraine With Aura Other Serious 10/16/2006 69 Male 157 lb 7/8/2010 Consumer United States
Primary
Concomitant
Somatisation Disorder Other Serious 1/1/2002 38 Female 256 lb 7/9/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 16 Female 7/19/2010 Consumer Czech Republic
Primary
Secondary
Concomitant
Headache 12/1/2009 57 Female 203 lb 9/14/2010 Consumer United States
Primary
Concomitant
Sleep Disorder Other Serious 9/1/2008 44 Male 213 lb 9/16/2010 Physician United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/1998 46 Male 10/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypophosphataemia Life Threatening 7/27/2010 75 Female 10/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 11/1/2009 69 Female 209 lb 11/24/2010 Consumer United States
Primary
Concomitant
Basedow's Disease Other Serious 6/1/2010 42 Female 192 lb 11/24/2010 Physician United Kingdom
Primary
Concomitant
Pituitary Tumour Removal Other Serious 57 Male 11/25/2010 Consumer Germany
Primary
Concomitant
Yellow Skin Other Serious 1/1/2008 54 Female 11/25/2010 Physician United States
Primary
Concomitant
Subdural Haemorrhage Hospitalization 9/13/2010 40 Female 12/3/2010 Other Health Professional Czech Republic
Primary
Concomitant
Myalgia Other Serious 53 Female 10/28/2010 Physician Canada
Primary
Concomitant
Yellow Skin Other Serious 1/1/2008 54 Female 12/10/2010 Physician United States
Primary
Concomitant
Blister 11/24/2009 12/14/2010 Physician United States
Primary
Concomitant
Sleep Disorder Other Serious 9/1/2008 44 Male 213 lb 2/18/2010 Consumer United States
Primary
Concomitant
Macular Degeneration 10/1/2009 12/20/2010 Physician United States
Primary
Concomitant
Hypophosphataemia Life Threatening 7/27/2010 75 Female 12/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 1/12/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2009 43 Female 1/14/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 1/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 62 Female 1/21/2011 Physician United States
Primary
Secondary
Intentional Drug Misuse Death 53 Female 1/21/2011 Physician United States
Primary
Secondary
Sudden Death Death 61 Female 319 lb 2/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Other Serious 45 Female 2/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Eructation 11/1/2010 62 Female 2/16/2011 Consumer United States
Primary
Concomitant
Stress Hospitalization 1/1/2010 58 Female 180 lb 2/16/2011 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 10/1/2010 45 2/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2009 43 Female 2/21/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 2/20/2011 3/2/2011 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 10/1/2010 45 3/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 10/1/2010 45 3/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2009 43 Female 3/9/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 9/1/2010 59 Female 3/4/2011 Consumer Brazil
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 2/23/2011 88 Female 3/11/2011 Other Health Professional
Primary
Concomitant
Pruritus Other Serious 12/1/2009 56 Male 219 lb 3/23/2011 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2009 43 Female 3/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chest Pain 11/1/2009 49 Female 115 lb 3/25/2011 Consumer United States
Primary
Concomitant
Application Site Rash 9/1/2010 61 Female 3/25/2011 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 12/28/2010 74 Male 170 lb 3/24/2011 Consumer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 12/5/2010 3/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2009 43 Female 4/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 45 Female 4/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Agitation Other Serious 1/1/2011 58 Female 4/5/2011 United States
Primary
Concomitant
Asthenia 3/20/2011 66 Female 4/15/2011 Consumer United States
Primary
Concomitant
Asthenia 3/20/2011 66 Female 4/15/2011 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 3/23/2011 43 Female 4/18/2011 United States
Primary
Concomitant
Renal Failure Chronic Other Serious 1/1/2000 52 Female 140 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Injury Other Serious 9/15/2007 60 Female 190 lb 4/26/2011 Other Health Professional United States
Primary
Concomitant
Postoperative Wound Infection Other Serious 1/1/2009 55 Female 198 lb 4/27/2011 Physician United Kingdom
Primary
Concomitant
Dehydration Hospitalization 80 Female 5/9/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Osteoarthritis Other Serious Male 6/29/2011 Lawyer United States
Primary
Concomitant
Ataxia Other Serious 2/1/2011 63 Male 170 lb 9/7/2011 Pharmacist Brazil
Primary
Concomitant
Skin Lesion Other Serious 12/1/2010 63 Male 170 lb 9/7/2011 Pharmacist Brazil
Primary
Concomitant
Interacting
Diarrhoea Other Serious 1/1/2011 63 Male 170 lb 9/7/2011 Pharmacist Brazil
Primary
Concomitant
Thrombocytopenia Other Serious 10/1/2010 63 Male 170 lb 9/8/2011 Pharmacist Brazil
Primary
Concomitant
Rash Macular Other Serious 12/1/2010 63 Male 170 lb 9/19/2011 Pharmacist Brazil
Primary
Concomitant
Ataxia Other Serious 2/1/2011 63 Male 170 lb 9/19/2011 Pharmacist Brazil
Primary
Concomitant
Palpitations Other Serious 11/30/2011 45 Female 12/16/2011 Other Health Professional Denmark
Primary
Concomitant
Renal Failure Acute Hospitalization 11/9/2011 75 Female 134 lb 12/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Activities Of Daily Living Impaired Other Serious 5/28/2012 47 Female 7/20/2012 Other Health Professional Denmark
Primary
Concomitant
Back Pain 8/5/2012 69 Female 185 lb 8/13/2012 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 80 Female 10/30/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/18/2012 66 Female 3/25/2013 Consumer Gb
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 2011 Female 11/7/2012 Consumer Gb
Primary
Secondary
Thyroid Disorder Hospitalization 2012 66 Female 141 lb 12/30/2012 Consumer Br
Primary
Concomitant
Thyroid Disorder Other Serious 45 Female 2/27/2013 Pharmacist Us
Primary
Secondary
Concomitant

Drug Data