Amitriptyline Hcl combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 5/25/2005 Female 2/24/2006 Physician Germany
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 10/24/2005 74 Female 195 lb 1/20/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 9/8/2004 Female 3/3/2006 Physician Germany
Primary
Secondary
Concomitant
Skin Laceration Hospitalization 11/29/2005 Female 154 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 5/18/2006 Physician Canada
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/1/1990 72 Male 5/24/2006 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 3/1/2006 57 Female 229 lb 4/20/2006 United States
Primary
Concomitant
Dyspnoea Other Serious 6/26/2006 53 Male 154 lb 7/3/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/3/2006 81 Female 7/26/2006 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 5/7/2005 71 Female 209 lb 8/10/2006 Physician United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 6/26/2006 53 Male 154 lb 8/17/2006 Consumer United States
Primary
Concomitant
Fluid Retention Other Serious 1/1/2006 70 Female 192 lb 7/19/2006 Physician United States
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 6/23/2006 46 Male 9/8/2006 Other Health Professional United States
Primary
Concomitant
Ulcer Hospitalization 9/1/2006 Male 150 lb 11/10/2006 Consumer Brazil
Primary
Concomitant
Ulcer Hospitalization 9/1/2006 Male 150 lb 11/10/2006 Consumer Brazil
Primary
Concomitant
Vomiting Hospitalization 7/16/2006 Female 227 lb 11/14/2006 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 7/16/2006 Female 227 lb 11/14/2006 Physician Germany
Primary
Concomitant
Death Death 12/7/2006 70 Female 12/15/2006 Consumer Canada
Primary
Concomitant
Arthralgia Hospitalization 11/28/2006 Female 12/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 12/6/2006 70 Female 12/19/2006 Physician Canada
Primary
Concomitant
Visual Disturbance Hospitalization Female 1/4/2007 Consumer United States
Primary
Concomitant
Rash Other Serious 10/24/2006 56 Male 210 lb 10/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Nasal Septum Perforation Death 2/14/2006 52 Female 130 lb 2/9/2007 Physician United States
Primary
Concomitant
Hypomagnesaemia Hospitalization 1/3/2007 48 Female 2/28/2007 Physician United States
Primary
Concomitant
Nasal Septum Perforation Death 2/14/2006 52 Female 130 lb 3/22/2007 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2002 Female 202 lb 4/4/2007 Physician United States
Primary
Secondary
Concomitant
Nasal Septum Perforation Death 2/14/2006 Female 130 lb 4/9/2007 Physician United States
Primary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 5/1/2007 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite 12/1/2006 60 Female 2/16/2007 United States
Primary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 5/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 53 Female 220 lb 6/11/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 6/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 6/24/2007 46 Female 181 lb 7/6/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 4/4/2001 Female 136 lb 7/12/2007 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 135 lb 7/12/2007 Physician United States
Primary
Secondary
Concomitant
Bacterial Infection Required Intervention 2/1/2007 46 Male 128 lb 7/10/2007 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 6/24/2007 46 Female 181 lb 8/29/2007 Physician United States
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 8/14/2007 58 Male 280 lb 9/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 1/1/2007 58 Male 10/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 8/14/2007 58 Male 280 lb 10/3/2007 United Kingdom
Primary
Secondary
Concomitant
Intra-abdominal Haematoma Other Serious 1/1/2007 Male 281 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 58 Male 10/15/2007 United Kingdom
Primary
Secondary
Concomitant
Death Death 10/5/2007 Female 154 lb 11/8/2007 Physician United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 4/15/2003 58 Female 11/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Skin Disorder Other Serious Female 12/3/2007 Other Health Professional Canada
Primary
Concomitant
Loss Of Libido 1/1/2003 59 Female 1/17/2008 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2008 Female 180 lb 1/18/2008 Consumer United States
Primary
Concomitant
Skin Disorder Other Serious Female 1/23/2008 Other Health Professional Canada
Primary
Concomitant
Pain Other Serious 1/1/2008 Female 180 lb 1/25/2008 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2008 Female 180 lb 1/30/2008 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2008 Female 180 lb 2/14/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 180 lb 3/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/1998 Male 4/14/2008 Lawyer United States
Primary
Secondary
Concomitant
Muscle Spasms 3/18/2008 63 Female 4/17/2008 Physician United States
Primary
Concomitant
Shock Life Threatening 4/3/2008 Male 5/30/2008 Other Health Professional France
Primary
Concomitant
Interacting
Death Death 10/5/2007 Female 154 lb 6/5/2008 Physician United Kingdom
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/1998 Male 6/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/1998 Male 6/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/29/2008 74 Male 6/13/2008 Physician Canada
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/30/2008 Female 320 lb 7/11/2008 Consumer United Kingdom
Primary
Concomitant
Dehydration Hospitalization 6/1/2008 Female 342 lb 7/30/2008 Consumer United States
Primary
Concomitant
Lung Disorder Hospitalization 4/1/2008 Female 342 lb 7/31/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 8/5/2008 Physician Germany
Primary
Secondary
Concomitant
Vision Blurred 7/1/2007 81 Female 8/26/2008 Consumer United States
Primary
Concomitant
Death Death Female 9/16/2008 Consumer United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 9/4/2008 Female 9/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Infarction Life Threatening 3/16/2008 Female 320 lb 10/1/2008 Consumer United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization Female 10/9/2008 Consumer United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/1998 Male 10/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/4/2008 Female 10/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Death Female 11/3/2008 Physician United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/1998 Male 11/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/4/2008 Female 11/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis 11/5/2008 Female 150 lb 11/7/2008 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 9/4/2008 Female 11/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Medication Residue 7/1/2008 51 Female 11/14/2008 United States
Primary
Concomitant
Oedema Peripheral Hospitalization Female 11/24/2008 Physician United States
Primary
Concomitant
Rash Hospitalization 9/8/2008 49 Female 12/1/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/4/2008 Female 12/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 12/12/2008 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 12/29/2008 Physician Germany
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 7/10/2008 Female 12/31/2008 Physician United Kingdom
Primary
Concomitant
Splenomegaly Hospitalization 67 Female 1/23/2009 Consumer United States
Primary
Concomitant
Splenomegaly Hospitalization 1/1/2009 67 Female 4/6/2009 Consumer United States
Primary
Concomitant
Death Death 4/21/2009 Female 5/1/2009 Physician United States
Primary
Concomitant
Subarachnoid Haemorrhage Required Intervention 3/31/2009 58 Male 134 lb 6/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Required Intervention 3/31/2009 58 Male 134 lb 6/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Renal Function Test Abnormal Disability 1/1/2006 Male 7/6/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/9/2008 65 Female 141 lb 7/27/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Oedema Hospitalization 63 Female 7/21/2009 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/9/2008 65 Female 141 lb 7/29/2009 Other Health Professional Germany
Primary
Concomitant
Interacting
Type 2 Diabetes Mellitus Other Serious 1/1/2000 47 Female 201 lb 7/30/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/9/2008 65 Female 7/31/2009 Consumer Germany
Primary
Secondary
Concomitant
Weight Increased Hospitalization 9/28/2005 71 Female 8/5/2009 United States
Primary
Concomitant
Vitamin D Deficiency Hospitalization 8/28/2008 61 Female 95 lb 8/25/2009 Pharmacist United States
Primary
Concomitant
Wheezing Death 60 Male 9/4/2009 United States
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 4/1/2008 Female 342 lb 11/16/2009 Other Health Professional United States
Primary
Concomitant
Dehydration Hospitalization 6/1/2008 Female 342 lb 11/16/2009 Other Health Professional United States
Primary
Concomitant
Wound Secretion Hospitalization Male 12/1/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 79 Male 12/11/2009 United States
Primary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 1/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Surgery Other Serious 59 Male 1/11/2010 United States
Primary
Concomitant
Pain Hospitalization Female 1/14/2010 United States
Primary
Concomitant
Multiple Injuries Other Serious 59 Male 1/21/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 79 Male 1/23/2010 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 66 Female 234 lb 1/27/2010 United States
Primary
Concomitant
Pain Other Serious 12/1/2009 Female 190 lb 2/12/2010 Physician United States
Primary
Concomitant
Death Death 2/10/2010 Female 130 lb 2/18/2010 Physician United States
Primary
Concomitant
Viral Infection Other Serious 1/1/2003 Female 165 lb 2/19/2010 Physician United States
Primary
Concomitant
Viral Infection Other Serious 1/1/2003 Female 165 lb 2/19/2010 Physician United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death Female 130 lb 2/23/2010 Physician United States
Primary
Concomitant
Renal Atrophy Other Serious Female 3/2/2010 Consumer Brazil
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/1998 Male 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/2/2010 Female 167 lb 3/9/2010 Physician United States
Primary
Concomitant
Trismus Other Serious 5/1/2007 Female 3/18/2010 Physician United States
Primary
Concomitant
Pain Other Serious 12/1/2009 Female 190 lb 3/17/2010 Physician United States
Primary
Concomitant
Viral Infection Other Serious 1/1/2004 Female 165 lb 3/19/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization Female 3/22/2010 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2007 Female 3/26/2010 Physician United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/1998 46 Male 4/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/2004 61 Female 165 lb 4/15/2010 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Hospitalization 3/16/2010 55 Female 160 lb 5/6/2010 Physician United States
Primary
Concomitant
Blood Sodium Decreased Hospitalization Female 110 lb 7/7/2010 Physician Germany
Primary
Concomitant
Tooth Extraction Other Serious 12/24/2009 57 Female 154 lb 7/28/2010 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 12/24/2009 57 Female 154 lb 8/6/2010 Physician Japan
Primary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 8/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/2004 61 Female 165 lb 8/26/2010 United States
Primary
Concomitant
Pruritus 1/1/2010 73 Female 158 lb 8/28/2010 Consumer United States
Primary
Concomitant
Ovarian Cyst Hospitalization 1/1/2010 36 Female 111 lb 9/8/2010 Consumer United States
Primary
Concomitant
Tremor Hospitalization 7/11/2010 80 Female 9/16/2010 Consumer Colombia
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 65 Female 9/2/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 175 lb 9/20/2010 United States
Primary
Concomitant
Tooth Extraction Other Serious 12/24/2009 57 Female 154 lb 10/15/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/9/2008 65 Female 11/24/2010 Consumer Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/9/2008 65 Female 141 lb 11/26/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 61 Male 12/22/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/1/2007 42 Female 1/13/2011 Other Health Professional United States
Primary
Concomitant
Dry Skin Disability 1/1/2004 47 Female 206 lb 1/6/2011 Lawyer United States
Primary
Concomitant
Bone Disorder Other Serious 1/1/2001 44 Female 206 lb 1/13/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 10/1/2010 72 Female 180 lb 1/14/2011 Consumer United States
Primary
Concomitant
Arthralgia 11/4/2010 56 Female 1/30/2011 Consumer United States
Primary
Concomitant
Duodenal Scarring Other Serious 61 Male 2/8/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Atelectasis Other Serious 1/1/2004 61 Female 165 lb 2/10/2011 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 7/10/2008 62 Female 154 lb 2/24/2011 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 61 Male 4/20/2011 Physician Netherlands
Primary
Concomitant
Paraesthesia Other Serious Female 291 lb 5/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 2/3/2004 38 Female 244 lb 5/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Groin Pain Disability 4/1/2001 70 Female 118 lb 5/17/2011 Lawyer United States
Primary
Concomitant

Drug Data