Amitriptyline Hcl combined with Naproxen

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Death 12/25/2005 57 Male 235 lb 1/13/2006 Other Health Professional United States
Primary
Concomitant
Tonic Clonic Movements Other Serious 12/26/2005 40 Female 157 lb 1/30/2006 Physician United States
Primary
Concomitant
Tonic Clonic Movements Other Serious 12/26/2005 40 Female 157 lb 1/30/2006 Physician United States
Primary
Concomitant
Pneumonia Death 12/25/2005 57 Male 235 lb 2/14/2006 Other Health Professional United States
Primary
Concomitant
Viral Infection Other Serious 9/8/2005 45 Male 2/10/2006 Physician United Kingdom
Primary
Concomitant
Renal Failure Death 12/25/2005 57 Male 235 lb 2/24/2006 Other Health Professional United States
Primary
Concomitant
Tonic Clonic Movements Other Serious 12/26/2005 40 Female 157 lb 3/3/2006 Physician United States
Primary
Concomitant
Skin Laceration Other Serious 12/26/2005 40 Female 157 lb 3/3/2006 Physician United States
Primary
Concomitant
Rash Maculo-papular Other Serious 11/1/2005 42 Male 198 lb 3/17/2006 United Kingdom
Primary
Concomitant
Leg Amputation Hospitalization 1/20/2006 37 Male 150 lb 3/16/2006 Physician Netherlands
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/11/2006 35 Female 230 lb 5/24/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/11/2006 35 Female 230 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 5/9/2006 Male 176 lb 6/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Oesophageal Ulcer Required Intervention 2/3/2006 71 Female 8/21/2006 Denmark
Primary
Concomitant
Vomiting Other Serious 63 Male 8/31/2006 Physician Turkey
Primary
Secondary
Vomiting Other Serious 41 Male 8/31/2006 Physician Turkey
Primary
Secondary
Myositis 6/2/2006 Male 212 lb 9/7/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Other Serious 8/31/2006 37 Female 135 lb 9/14/2006 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 5/11/2006 35 Female 230 lb 9/18/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/11/2006 35 Female 230 lb 10/2/2006 Physician United States
Primary
Concomitant
Meningitis Viral Hospitalization 5/25/2006 Female 10/19/2006 Canada
Primary
Concomitant
Suicide Attempt Hospitalization 6/25/2006 45 Male 10/30/2006 Consumer United States
Primary
Secondary
Pulmonary Oedema Hospitalization 9/12/2006 65 Female 114 lb 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 9/12/2006 65 Female 114 lb 12/5/2006 Physician United States
Primary
Secondary
Concomitant
Atrioventricular Block Complete Hospitalization Female 160 lb 1/4/2007 Pharmacist United States
Primary
Concomitant
Fatigue 9/8/2005 36 Female 12/29/2006 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 11/1/2006 Female 154 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Hospitalization 5/20/2005 61 Male 194 lb 2/6/2007 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 9/13/2006 71 Male 257 lb 9/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Male 11/13/2006 Physician United States
Primary
Concomitant
Tremor Other Serious 4/1/2005 67 Female 3/30/2007 France
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2002 Female 202 lb 4/4/2007 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 4/1/2005 67 Female 4/2/2007 Other Health Professional France
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Skin Exfoliation Other Serious 11/24/2006 54 Male 186 lb 2/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Scrotal Irritation Required Intervention 11/16/2006 Male 165 lb 11/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ocular Hyperaemia Other Serious 12/18/2006 89 Male 205 lb 1/17/2007 Physician United States
Primary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 5/1/2007 Physician United States
Primary
Secondary
Concomitant
Presyncope Hospitalization 5/11/2006 35 Female 230 lb 5/2/2007 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 9/15/2006 67 Female 5/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 67 Female 5/11/2007 France
Primary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 5/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 43 Female 5/24/2007
Primary
Secondary
Tremor Hospitalization 4/1/2005 67 Female 5/21/2007 France
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 4/1/2007 Female 5/30/2007 Consumer Canada
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Whiplash Injury Other Serious 1/1/2006 Female 152 lb 6/21/2007 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 3/24/2002 48 Female 275 lb 5/24/2007 Physician United States
Primary
Secondary
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 6/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Sclerosis Hospitalization 6/16/2007 47 Female 170 lb 7/5/2007 United States
Primary
Concomitant
Hypoaesthesia Other Serious 10/6/2006 Male 181 lb 7/16/2007 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/16/2007 33 Male 225 lb 7/17/2007 Physician Ireland
Primary
Concomitant
Hip Arthroplasty Hospitalization 6/20/2007 Female 110 lb 7/18/2007 Canada
Primary
Concomitant
Oedema Peripheral Hospitalization 7/8/2007 64 Male 222 lb 7/10/2007 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 7/10/2004 27 Female 148 lb 6/8/2007 Other Health Professional United States
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 6/16/2007 47 Female 170 lb 7/23/2007 Physician United States
Primary
Concomitant
Hypoaesthesia Other Serious 10/6/2006 Male 181 lb 7/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hip Arthroplasty Hospitalization 6/20/2007 Female 110 lb 7/30/2007 Canada
Primary
Concomitant
Gastric Cancer Other Serious Male 220 lb 8/8/2007 Canada
Primary
Concomitant
Septic Shock Hospitalization 1/1/2007 Male 209 lb 9/6/2007 Other Health Professional Germany
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2004 24 Female 181 lb 9/18/2007 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 3/24/2002 48 Female 276 lb 9/21/2007 United States
Primary
Secondary
Pain In Extremity Other Serious 5/1/2007 68 Male 198 lb 10/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Presyncope Hospitalization 5/11/2006 35 Female 230 lb 10/11/2007 Physician United States
Primary
Concomitant
Rash Other Serious 10/3/2007 52 Female 162 lb 10/5/2007 Pharmacist United States
Primary
Concomitant
Pain In Extremity Other Serious 5/1/2007 68 Male 198 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Discolouration 1/16/2007 70 Female 11/14/2007 Consumer United States
Primary
Concomitant
Necrotising Retinitis Other Serious 9/1/2007 54 Female 11/26/2007
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/13/2007 54 Female 214 lb 11/27/2007 United States
Primary
Concomitant
Whiplash Injury Other Serious 1/1/2006 Female 152 lb 1/9/2008 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 11/25/2007 Female 173 lb 1/22/2008 Physician United States
Primary
Concomitant
Respiratory Arrest Death 52 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 52 Male 1/22/2008 Physician United States
Primary
Secondary
Drug Toxicity Death 52 Male 1/28/2008 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 52 Male 1/29/2008 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 2/1/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 52 Male 1/25/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 52 Male 2/5/2008 Physician United States
Primary
Secondary
Sinus Bradycardia Other Serious 43 Female 2/19/2008 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 3/1/2006 Female 3/14/2008 Physician United Kingdom
Primary
Concomitant
Turner's Syndrome Hospitalization 12/31/2007 55 Female 3/14/2008 Consumer United States
Primary
Concomitant
Drug Toxicity Death 52 Male 3/25/2008 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 52 Male 3/25/2008 Physician Germany
Primary
Secondary
Drug Toxicity Death 52 Male 3/25/2008 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 3/26/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 3/26/2008 Physician United States
Primary
Secondary
No Adverse Event 67 Female 4/18/2008 France
Primary
Secondary
Dyspnoea 4/4/2008 Consumer United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 12/31/2007 55 Female 5/2/2008 Consumer United States
Primary
Concomitant
Somnolence 1/1/2003 Male 220 lb 5/14/2008 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/9/2008 Female 161 lb 5/27/2008
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/9/2008 62 Female 161 lb 6/5/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 2/12/2002 Male 168 lb 6/6/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/9/2008 Female 172 lb 6/10/2008
Primary
Secondary
Concomitant
Weight Increased Hospitalization 2/1/2002 Male 168 lb 6/11/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 3/11/2008 40 Female 178 lb 6/12/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/20/2006 Female 170 lb 6/18/2008 Physician Canada
Primary
Concomitant
Pancreatitis Acute Hospitalization 4/20/2008 45 Female 6/11/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/9/2008 62 Female 172 lb 6/26/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/27/2002 49 Female 7/10/2008 Physician United Kingdom
Primary
Concomitant
Syncope Hospitalization 2/5/2008 Female 134 lb 7/30/2008 United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 8/25/2000 65 Female 236 lb 8/18/2008 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Other Serious 3/11/2008 Female 178 lb 8/19/2008 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 3/10/2008 Female 181 lb 8/20/2008 United Kingdom
Primary
Concomitant
Drug Toxicity Death 1/1/2006 52 Male 8/18/2008 Physician United States
Primary
Concomitant
Weight Increased 7/26/2007 72 Female 1/30/2008 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 68 Male 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 8/25/2000 65 Female 236 lb 10/2/2008 Lawyer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 12/31/2007 55 Female 9/29/2008 United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 Male 10/10/2008 Pharmacist Canada
Primary
Concomitant
Skin Ulcer Other Serious 12/31/2007 55 Female 10/20/2008 United States
Primary
Concomitant
Oesophageal Ulcer Required Intervention 2/3/2006 71 Female 10/22/2008 Denmark
Primary
Concomitant
Septic Shock Hospitalization 4/3/2008 Female 298 lb 10/29/2008 United Kingdom
Primary
Concomitant
Wound Secretion Hospitalization 9/1/2008 Female 10/28/2008 Consumer United States
Primary
Concomitant
Venous Insufficiency Hospitalization 9/1/2008 Female 12/1/2008 Physician United States
Primary
Concomitant
Treatment Failure Other Serious 1/1/2008 Male 12/2/2008 Physician Canada
Primary
Concomitant
Completed Suicide Death 43 Male 12/30/2008 Pharmacist United States
Primary
Secondary
Anal Haemorrhage Other Serious 12/12/2008 Female 1/14/2009 Consumer United Kingdom
Primary
Concomitant
Drug Toxicity Death 43 Male 1/14/2009 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 43 Male 1/21/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 43 Male 1/23/2009 Physician United States
Primary
Secondary
Completed Suicide Death 43 Male 1/28/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 43 Male 1/15/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 43 Male 1/21/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 43 Male 1/23/2009 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious 1/1/2008 Male 2/19/2009 Physician Canada
Primary
Concomitant
Skin Burning Sensation 12/4/2007 42 Male 189 lb 1/8/2009 United States
Primary
Concomitant
Diabetes Mellitus Death 12/4/2005 55 Female 227 lb 4/2/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 Female 3/27/2009 Canada
Primary
Concomitant
Syncope Other Serious 12/17/2002 58 Male 185 lb 4/3/2009 United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2005 42 Female 257 lb 4/3/2009 United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/1998 51 Male 214 lb 5/20/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 12/11/2003 23 Female 196 lb 6/15/2009 United States
Primary
Concomitant
Skin Cancer Other Serious 4/20/2009 Female 170 lb 6/26/2009 Physician United States
Primary
Concomitant
Diabetic Retinopathy Other Serious 9/3/2004 50 Male 220 lb 7/27/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 47 Female 201 lb 7/30/2009 United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2007 68 Male 7/28/2009 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2008 Female 128 lb 1/22/2010 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 74 Female 1/13/2010 United States
Primary
Concomitant
Pain Hospitalization Female 1/14/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2007 48 Male 170 lb 2/23/2010 Physician United States
Primary
Secondary
Concomitant
Endometrial Cancer Other Serious 9/29/2008 55 Female 2/25/2010 Consumer United States
Primary
Secondary
Concomitant
Incoherent Other Serious 10/1/2009 52 Male 170 lb 3/3/2010 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious Female 3/5/2010 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 2/23/2010 Female 214 lb 3/15/2010 Physician United Kingdom
Primary
Concomitant
Myoclonus Other Serious 53 Male 3/16/2010 Physician Australia
Primary
Concomitant
Pancreatitis Chronic Other Serious 12/1/2007 Male 220 lb 3/19/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/24/2008 32 Female 210 lb 3/16/2010 United States
Primary
Secondary
Concomitant

Drug Data