Amitriptyline Hcl combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Fall Death 1/8/2006 44 Female 278 lb 1/18/2006 Consumer United States
Primary
Concomitant
Respiratory Failure Life Threatening 9/15/2005 80 Female 154 lb 1/20/2006 Physician Germany
Primary
Concomitant
Troponin Increased Other Serious 1/1/2005 63 Female 1/27/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2005 63 Female 1/31/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 52 Female 2/7/2006
Primary
Secondary
Extravasation Hospitalization 12/12/2005 61 Male 176 lb 2/8/2006 Physician Australia
Primary
Secondary
Concomitant
Transfusion Reaction Other Serious 2/1/2004 57 Male 2/8/2006 Canada
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 10/10/2005 65 Male 2/13/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 2/24/2006 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 11/25/2005 63 Male 2/21/2006 Physician France
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 68 Male 4/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/1999 16 Female 265 lb 5/8/2006 Lawyer United States
Primary
Concomitant
Sudden Death Death 1/8/2006 44 Female 269 lb 5/10/2006 Physician United States
Primary
Secondary
Concomitant
Shock Other Serious 2/1/2006 23 Male 170 lb 4/28/2006 Physician Thailand
Primary
Secondary
Concomitant
Hypertensive Cardiomyopathy Death 9/19/2005 48 Female 150 lb 5/9/2006 Physician United States
Primary
Concomitant
Shock Other Serious 2/1/2006 23 Male 170 lb 5/12/2006 Physician Thailand
Primary
Secondary
Concomitant
Progesterone Receptor Assay Positive Other Serious 2/1/2004 51 Female 155 lb 5/16/2006 Physician United States
Primary
Concomitant
Extravasation Hospitalization 12/12/2005 61 Male 176 lb 5/16/2006 Physician Australia
Primary
Secondary
Concomitant
Pyelonephritis Death 1/8/2006 44 Female 591 lb 5/23/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/4/2006 56 Male 139 lb 5/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 2/27/2005 77 Female 5/25/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Somnolence Hospitalization 12/20/2004 87 Female 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Middle Insomnia 2/15/2006 51 Female 162 lb 4/3/2006 Consumer United States
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/1999 16 Female 265 lb 6/22/2006 Lawyer United States
Primary
Concomitant
Ventricular Fibrillation Death 1/8/2006 45 Female 591 lb 6/26/2006 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2005 Female 6/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Psychotic Disorder Hospitalization 1/1/1999 16 Female 265 lb 6/30/2006 Lawyer United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 1/1/1999 16 Female 265 lb 7/27/2006 Lawyer United States
Primary
Concomitant
Renal Failure Life Threatening 5/15/2006 69 Female 7/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 1/1/1999 16 Female 265 lb 8/4/2006 Lawyer United States
Primary
Concomitant
Serotonin Syndrome Death 79 Female 8/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
White Blood Cell Count Increased Hospitalization 9/1/2005 66 Male 185 lb 8/15/2006 United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/1999 16 Female 265 lb 8/17/2006 Lawyer United States
Primary
Concomitant
Neutropenia Other Serious 7/10/2006 69 Male 137 lb 8/17/2006 Belgium
Primary
Concomitant
Sleep Disorder Other Serious 41 Male 8/30/2006
Primary
Secondary
White Blood Cell Count Increased Hospitalization 9/1/2005 66 Male 185 lb 8/31/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/1/2005 66 Male 185 lb 9/8/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/1/2005 66 Male 185 lb 9/12/2006 United States
Primary
Concomitant
Vomiting Other Serious 63 Male 8/31/2006 Physician Turkey
Primary
Secondary
Vomiting Other Serious 41 Male 8/31/2006 Physician Turkey
Primary
Secondary
Neutropenia Other Serious 7/10/2006 69 Male 137 lb 8/25/2006 Belgium
Primary
Concomitant
Haemorrhage Other Serious 9/8/2006 42 Female 9/21/2006 Pharmacist Canada
Primary
Concomitant
Nausea Hospitalization 9/25/2006 44 Male 283 lb 9/26/2006 Pharmacist United States
Primary
Concomitant
Staphylococcal Sepsis Death 54 Female 9/29/2006
Primary
Secondary
Wound Infection Staphylococcal Other Serious 9/5/2006 54 Female 198 lb 10/2/2006 Physician United States
Primary
Concomitant
Skin Infection Hospitalization 5/1/2005 Female 305 lb 10/19/2006 Physician United States
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Pain Required Intervention 1/1/2004 Female 10/19/2006 Lawyer United States
Primary
Concomitant
Off Label Use Death Female 11/6/2006 Consumer Canada
Primary
Concomitant
White Blood Cell Count Increased 10/1/2006 44 Male 130 lb 10/19/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Life Threatening 11/1/2005 50 Male 209 lb 11/13/2006 United States
Primary
Concomitant
Hallucination Other Serious 7/26/2006 70 Male 208 lb 8/15/2006 Physician United States
Primary
Concomitant
Nicotine Dependence 55 Female 12/20/2006 Consumer United States
Primary
Concomitant
Vertigo Other Serious 10/1/2006 Male 172 lb 12/28/2006 Physician France
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 12/13/2006 Female 1/4/2007 Consumer Canada
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 1/15/2007 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2004 Female 1/22/2007 Lawyer United States
Primary
Concomitant
Persistent Foetal Circulation Hospitalization Male 1/23/2007
Primary
Secondary
Rash Other Serious 10/24/2006 56 Male 210 lb 10/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Completed Suicide Death Unknown 1/25/2007 Physician United States
Primary
Secondary
Vomiting Other Serious 65 Female 2/28/2007 Consumer United States
Primary
Concomitant
Syncope Other Serious 12/18/2002 Female 3/8/2007 Consumer United States
Primary
Concomitant
Syncope Other Serious 12/18/2002 Female 3/20/2007 Lawyer United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 79 Female 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Serotonin Syndrome Hospitalization 79 Female 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Urticaria Other Serious 1/1/2006 Female 4/16/2007 Consumer Canada
Primary
Secondary
Progesterone Receptor Assay Positive Other Serious 2/1/2004 48 Female 155 lb 4/9/2007 Physician United States
Primary
Concomitant
Somnolence Life Threatening 12/12/2006 57 Female 4/6/2007 Germany
Primary
Secondary
Concomitant
Jaundice Hospitalization 4/17/2007 Female 4/18/2007 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 79 Female 5/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Mental Disorder Hospitalization 3/16/2007 54 Female 4/18/2007 Physician France
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 79 Female 4/23/2007 United Kingdom
Primary
Secondary
Concomitant
Hiatus Hernia Hospitalization 1/1/2005 Male 5/7/2007 Consumer Brazil
Primary
Secondary
Concomitant
Hyperaesthesia Other Serious 62 Male 159 lb 5/29/2007 Other Health Professional Belgium
Primary
Secondary
Concomitant
Spleen Disorder Death 1/8/2004 79 Female 5/24/2007 Physician
Primary
Concomitant
Tendonitis Hospitalization 10/1/2005 62 Male 5/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tendonitis Hospitalization 10/1/2005 62 Male 6/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 6/4/2007 70 Female 6/22/2007 Physician Brazil
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 34 Male 7/2/2007 Consumer Germany
Primary
Concomitant
Ulcer Hospitalization 10/1/2005 62 Male 157 lb 7/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Haemoptysis Death 1/22/2007 Male 132 lb 7/11/2007 Other Health Professional Australia
Primary
Concomitant
Pulmonary Oedema Death 4/24/2007 19 Male 7/12/2007
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 135 lb 7/12/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 6/4/2007 68 Female 7/20/2007 Physician Brazil
Primary
Concomitant
Pleural Effusion Other Serious 6/4/2007 68 Female 7/26/2007 Physician Brazil
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 32 Female 7/26/2007 Pharmacist Germany
Primary
Concomitant
Intestinal Obstruction Other Serious 7/15/2007 65 Female 8/6/2007 Pharmacist United Kingdom
Primary
Concomitant
Urethral Polyp Hospitalization 60 Female 8/6/2007 Physician United States
Primary
Concomitant
Pancreatic Carcinoma Metastatic Hospitalization 4/17/2007 Female 8/14/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 56 Female 8/24/2007
Primary
Secondary
Convulsion Hospitalization 8/1/2007 65 Male 179 lb 8/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 8/19/2007 58 190 lb 8/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 6/4/2007 68 Female 8/30/2007 Physician Brazil
Primary
Concomitant
Vomiting 4/19/2007 54 Male 7/11/2007 Consumer United States
Primary
Concomitant
Drug Toxicity Death 4/29/2005 Male 250 lb 9/5/2007 Physician United States
Primary
Concomitant
Pleural Effusion Other Serious 6/4/2007 68 Female 9/12/2007 Physician Brazil
Primary
Concomitant
Vomiting Other Serious 3/1/2007 Male 9/13/2007 Physician Germany
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious Female 152 lb 9/18/2007 Physician United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 8/19/2007 58 Male 190 lb 9/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 5/31/2007 65 Male 9/27/2007 Other Health Professional Netherlands
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 8/1/2007 65 Male 179 lb 10/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2000 71 Female 10/20/2007 United States
Primary
Secondary
Concomitant
Urethral Polyp Hospitalization 7/10/2007 60 Female 10/22/2007 Physician United States
Primary
Concomitant
Red Cell Distribution Width Increased Hospitalization 8/1/2007 65 Male 179 lb 8/23/2007 South Africa
Primary
Secondary
Concomitant
White Blood Cell Analysis Increased Other Serious 1/1/2000 71 Female 11/22/2007 United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 8/19/2007 58 Male 190 lb 11/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 12/20/2007 Female 110 lb 1/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 52 Female 1/23/2008
Primary
Secondary
Concomitant
Respiratory Arrest Death 52 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 52 Male 1/22/2008 Physician United States
Primary
Secondary
Drug Toxicity Death 52 Male 1/28/2008 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 52 Male 1/29/2008 Other Health Professional United States
Primary
Secondary
Sudden Death Other Serious 1/1/2008 United Kingdom
Primary
Secondary
Respiratory Arrest Death 52 Male 2/5/2008 Physician United States
Primary
Secondary
Lung Adenocarcinoma Metastatic Other Serious 5/10/2007 Female 117 lb 2/8/2008 South Africa
Primary
Concomitant
Pain Hospitalization 5/1/2006 Male 140 lb 2/21/2008 Consumer United States
Primary
Secondary
Concomitant
Somnolence Hospitalization Female 2/25/2008
Primary
Secondary
Concomitant
Intentional Drug Misuse Death 28 Female 3/4/2008 United Kingdom
Primary
Secondary
Respiratory Arrest Death 2/10/2008 Male 3/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/14/2008 Female 357 lb 3/6/2008 Pharmacist United Kingdom
Primary
Concomitant
Sinus Tachycardia Other Serious 44 Male 3/7/2008
Primary
Secondary
Concomitant
Supraventricular Tachycardia Life Threatening 2/8/2008 Male 181 lb 2/22/2008 Consumer United States
Primary
Concomitant
Respiratory Arrest Death 2/10/2008 Male 3/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 8/19/2007 58 Male 190 lb 2/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 3/19/2008 Physician United States
Primary
Secondary
Hyperaesthesia Hospitalization 3/25/2008 Physician Italy
Primary
Secondary
Concomitant
Drug Toxicity Death 52 Male 3/25/2008 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 52 Male 3/25/2008 Physician Germany
Primary
Secondary
Drug Toxicity Death 52 Male 3/25/2008 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 3/26/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 3/26/2008 Physician United States
Primary
Secondary
Acute Coronary Syndrome Other Serious 8/19/2007 58 Male 190 lb 3/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 12/19/2007 Female 110 lb 4/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Trigeminal Neuralgia Other Serious 12/29/2001 58 Female 4/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pain Hospitalization 5/1/2006 Male 140 lb 4/24/2008 Consumer United States
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious Female 134 lb 4/29/2008 Physician United Kingdom
Primary
Concomitant
Trigeminal Neuralgia Other Serious 12/29/2001 58 Female 5/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 150 lb 5/16/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2006 Female 135 lb 5/23/2008 Consumer United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 12/29/2001 58 Female 6/3/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/20/2008 Female 256 lb 6/4/2008 Consumer United Kingdom
Primary
Concomitant
Substance Abuse Other Serious 57 Female 6/6/2008 Physician Canada
Primary
Secondary
Drug Toxicity Other Serious 6/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 10/1/2004 Female 260 lb 6/9/2008 Consumer United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 12/29/2001 58 Female 6/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 6/4/2007 68 Female 6/13/2008 Physician Brazil
Primary
Concomitant
Bronchopneumonia Other Serious 45 Male 6/16/2008 Physician Canada
Primary
Secondary
Respiratory Arrest Other Serious 74 Male 6/19/2008 Physician United States
Primary
Secondary

Drug Data