Amitriptyline Hcl combined with Morphine Sulfate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Other Serious 4/8/2001 25 Female 110 lb 1/3/2006 Physician United States
Primary
Secondary
Concomitant
Polysubstance Abuse Hospitalization 8/3/2004 51 Male 155 lb 1/9/2006 Other Health Professional United States
Primary
Secondary
Pruritus Other Serious 1/12/2006 40 Female 232 lb 1/13/2006 Pharmacist United States
Primary
Concomitant
Septic Shock Other Serious 3/1/2005 Female 1/20/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Death 1/1/2004 Female 2/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Staphylococcal Infection Hospitalization 9/16/2005 Female 139 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 Female 139 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 3/24/2005 52 Male 148 lb 4/25/2006 Physician Canada
Primary
Secondary
Concomitant
Pustular Psoriasis Disability 2/16/2006 48 Female 209 lb 5/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious 2/27/2005 77 Female 5/25/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 9/26/2005 Female 6/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/22/2005 62 Male 6/2/2006 France
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 Female 139 lb 8/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus 4/24/2006 45 Female 7/12/2006 United States
Primary
Concomitant
Substance Abuse Death 9/2/2004 35 Female 254 lb 7/17/2006 Other Health Professional United States
Primary
Secondary
Multiple Drug Overdose Intentional Death 1/14/2004 47 Male 7/17/2006 Physician United States
Primary
Secondary
Sleep Disorder Required Intervention 41 Male 8/24/2006 Physician Germany
Primary
Secondary
Pruritus Required Intervention 9/21/2006 64 Male 171 lb 9/21/2006 Pharmacist United States
Primary
Concomitant
Vascular Access Complication Other Serious 54 Female 9/27/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Respiratory Distress Death 9/23/2005 51 Male 9/26/2006 France
Primary
Secondary
Concomitant
Unevaluable Event Life Threatening 9/23/2005 51 Male 143 lb 9/29/2006 Other Health Professional France
Primary
Secondary
Concomitant
Oedema Other Serious 7/10/2006 59 Male 220 lb 7/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
Completed Suicide Death 11/21/2006 Physician United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 10/1/2006 44 Male 130 lb 11/8/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 37 Female 99 lb 12/19/2006
Primary
Secondary
Concomitant
Vomiting Other Serious 4/18/2003 42 Female 111 lb 2/16/2007 Lawyer United States
Primary
Concomitant
Pneumonia Hospitalization 2/14/2007 52 Male 200 lb 3/2/2007 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 79 Female 3/16/2007 United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 3/27/2006 Female 130 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
Tachycardia Life Threatening 79 Female 4/26/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Somnolence Other Serious 9/1/2005 60 Female 4/30/2007
Primary
Concomitant
Vomiting Other Serious 4/18/2003 5/30/2007 Lawyer United States
Primary
Concomitant
Hyperaesthesia Hospitalization 1/1/2006 62 Male 6/21/2007 Other Health Professional Belgium
Primary
Secondary
Concomitant
Tachycardia Hospitalization 79 Female 6/28/2007 United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 3/27/2006 Female 130 lb 7/20/2007 Consumer United Kingdom
Primary
Concomitant
Sepsis Other Serious 3/27/2006 Female 130 lb 7/30/2007 Consumer United Kingdom
Primary
Concomitant
Viral Infection Other Serious 12/9/2006 Female 183 lb 8/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Dependence Death 5/11/2005 54 Male 145 lb 6/7/2007 Physician United States
Primary
Secondary
Multiple Drug Overdose Accidental Death 8/29/2004 32 Female 148 lb 6/7/2007 Other Health Professional United States
Primary
Secondary
Urinary Incontinence Other Serious 11/29/2006 50 Male 187 lb 9/14/2007
Primary
Concomitant
Joint Arthroplasty Other Serious 3/2/2007 Female 121 lb 10/19/2007 United Kingdom
Primary
Concomitant
Renal Tubular Necrosis Death 9/4/2007 63 Male 152 lb 10/31/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Tubular Necrosis Death 9/4/2007 63 Male 152 lb 11/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Life Threatening 79 Female 11/9/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Restless Legs Syndrome Other Serious 35 Female 192 lb 1/2/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 1/1/2006 37 Male 1/22/2008 United States
Primary
Secondary
Swelling Face Other Serious 56 Female 2/1/2008 Other Health Professional United Kingdom
Primary
Concomitant
Spinal Compression Fracture Other Serious 7/17/2007 Male 218 lb 2/25/2008 United Kingdom
Primary
Concomitant
Somnolence Other Serious 27 Female 3/3/2008 Physician Italy
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/21/2006 59 Female 3/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperaesthesia Hospitalization 1/1/2008 27 Female 4/30/2008 Physician Italy
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 5/1/2007 Female 5/29/2008 Physician Canada
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Hospitalization 4/20/2008 63 Male 119 lb 6/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 5/1/2007 Female 6/27/2008 Physician Canada
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/20/2008 52 Female 6/30/2008 Other Health Professional France
Primary
Concomitant
Pyrexia Death 4/3/2008 37 Male 7/8/2008 United States
Primary
Concomitant
Weight Increased Other Serious 3/21/2001 47 Female 245 lb 10/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Depression Other Serious Male 11/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1991 Male 188 lb 11/21/2008 United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 6/21/2006 67 Female 146 lb 12/22/2008 Physician Sweden
Primary
Secondary
Concomitant
Vomiting Other Serious 4/4/2008 Female 176 lb 1/14/2009 United Kingdom
Primary
Concomitant
Vomiting Other Serious 4/4/2008 Female 176 lb 1/15/2009 United Kingdom
Primary
Concomitant
Completed Suicide Death 43 Male 1/28/2009 Other Health Professional United States
Primary
Secondary
Rheumatoid Arthritis Hospitalization 4/4/2007 Female 126 lb 2/2/2009 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 4/4/2007 Female 126 lb 2/5/2009 United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 80 Male 3/17/2009
Primary
Secondary
Concomitant
Skin Laceration Other Serious 1/1/2003 40 Female 150 lb 4/14/2009 United States
Primary
Concomitant
Pain Other Serious 7/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 1/1/2008 Female 135 lb 8/12/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/25/2006 74 Female 170 lb 9/1/2009 United States
Primary
Concomitant
Inflammation Hospitalization 9/30/2009 Female 10/29/2009 Other Health Professional France
Primary
Concomitant
Inflammation Hospitalization 9/30/2009 Female 11/11/2009 Other Health Professional France
Primary
Concomitant
Pulmonary Embolism Other Serious Female 11/25/2009 Physician United Kingdom
Primary
Concomitant
Syncope Hospitalization 76 Male 1/13/2010 United States
Primary
Concomitant
Drug Withdrawal Syndrome Hospitalization Female 1/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 76 Male 1/19/2010 United States
Primary
Concomitant
Drug Withdrawal Syndrome Neonatal Hospitalization Female 2/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 5/11/2009 Female 133 lb 3/2/2010 Physician United Kingdom
Primary
Concomitant
Vascular Insufficiency Other Serious 10/1/2007 77 Female 3/4/2010 Lawyer United States
Primary
Concomitant
Myoclonus Other Serious 53 Male 3/16/2010 Physician Australia
Primary
Concomitant
Myoclonus Other Serious 64 Male 3/18/2010 Physician Australia
Primary
Concomitant
Myoclonus Other Serious 53 Male 4/15/2010 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2010 59 Female 5/11/2010 Physician France
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 6/23/2010 69 Male 174 lb 7/7/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/1991 54 Male 188 lb 8/20/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 9/14/2010 United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 9/17/2010 United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 6/23/2010 69 Male 174 lb 9/17/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Pancreatitis Other Serious 4/1/1999 42 Female 115 lb 9/20/2010 United States
Primary
Concomitant
Death Hospitalization 1/31/2006 41 Male 10/25/2010 Consumer Israel
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/13/2010 67 Male 164 lb 10/29/2010 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 9/20/2010 85 Male 139 lb 11/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 65 Male 188 lb 11/8/2010 Consumer United States
Primary
Secondary
Concomitant
Multi-organ Failure Death Male 11/11/2010 Other Health Professional United States
Primary
Concomitant
Porphyria Acute Life Threatening 10/20/2010 66 Male 146 lb 11/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 11/18/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 65 Male 188 lb 11/18/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 65 Male 188 lb 11/24/2010 United States
Primary
Secondary
Concomitant
Injection Site Pruritus 9/1/2010 38 Male 1/29/2011 Consumer United States
Primary
Concomitant
Device Malfunction 9/2/2010 37 Male 1/30/2011 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 6/23/2010 69 Male 174 lb 2/4/2011 Physician Belgium
Primary
Secondary
Concomitant
Blood Chloride Decreased Death 1/1/2009 54 Female 2/4/2011 Physician United States
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 4/9/2009 47 Female 152 lb 3/11/2011 Physician Canada
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Life Threatening 11/17/2009 36 Male 4/15/2011 Other Health Professional France
Primary
Secondary
Concomitant
Ileitis Hospitalization 11/9/2009 36 Male 4/18/2011 Other Health Professional France
Primary
Secondary
Concomitant
Fall Hospitalization 85 Female 5/13/2011 Consumer United States
Primary
Concomitant
Vomiting 10/6/2010 42 Female 2/24/2011 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Death 40 Male 185 lb 5/19/2011 Physician United States
Primary
Secondary
Cardiomegaly Other Serious 1/1/2007 76 Female 166 lb 6/6/2011 United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2007 76 Female 166 lb 6/20/2011 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 6/15/2011 Consumer United States
Primary
Concomitant
Hyperhidrosis 5/13/2011 40 Male 6/27/2011 Pharmacist United Kingdom
Primary
Concomitant
Lung Neoplasm Other Serious 1/1/2004 38 Female 6/28/2011 United States
Primary
Concomitant
Lethargy Hospitalization 4/25/2011 62 Female 104 lb 6/30/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Headache Other Serious 12/17/2010 40 Female 7/7/2011 Physician Germany
Primary
Concomitant
Fear Other Serious 6/23/2006 51 Male 209 lb 7/6/2011 Lawyer United States
Primary
Concomitant
Injury Death 6/23/2006 51 Male 209 lb 7/7/2011 Lawyer United States
Primary
Concomitant
Nervous System Disorder Life Threatening 6/17/2011 51 Female 7/13/2011 United States
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 1/1/2007 82 Female 128 lb 7/14/2011 Physician France
Primary
Concomitant
Convulsion Death 1/1/2008 40 Male 7/15/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 68 Female 7/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Substance Abuse Death 50 Male 7/25/2011 Physician Canada
Primary
Secondary
Skin Discolouration Other Serious 1/1/2006 60 Female 249 lb 7/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucination, Visual Death 68 Female 7/15/2011 Physician United Kingdom
Primary
Secondary
Pancytopenia Other Serious 1/1/2007 82 Female 128 lb 7/26/2011 Physician France
Primary
Concomitant
Dysphagia Hospitalization 7/26/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Anaemia Hospitalization 6/29/2011 66 Male 8/1/2011 Physician United Kingdom
Primary
Concomitant
Confusional State Death 1/1/2010 39 Male 8/4/2011 Consumer United States
Primary
Secondary
Concomitant
Incoherent Hospitalization 1/1/2010 83 Female 8/2/2011 Consumer United States
Primary
Concomitant
Pneumonia Death 4/15/2011 56 Male 220 lb 8/12/2011 United States
Primary
Concomitant
Sepsis Life Threatening 7/11/2011 76 Female 8/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pruritus Life Threatening 6/17/2011 51 Female 8/24/2011 United States
Primary
Concomitant
Sudden Death Death 8/12/2011 61 Female 137 lb 8/25/2011 Physician United States
Primary
Concomitant
Pancytopenia Other Serious 5/10/2007 82 Female 128 lb 8/25/2011 Physician France
Primary
Concomitant
Neutropenia Life Threatening 7/11/2011 76 Female 8/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukopenia Life Threatening 7/19/2011 76 Female 8/24/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Arthritis Enteropathic Hospitalization 4/26/2011 47 Female 112 lb 8/31/2011 Physician Germany
Primary
Concomitant
Sepsis Life Threatening 7/11/2011 76 Female 8/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 5/8/2008 55 Female 8/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain Upper Other Serious 12/1/2005 39 Female 144 lb 9/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 6/29/2011 66 Male 9/4/2011 Physician United Kingdom
Primary
Concomitant
Neutropenic Sepsis Hospitalization 6/1/2007 9/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatotoxicity Life Threatening 3/6/2011 61 Female 157 lb 9/18/2011 Physician Germany
Primary
Secondary
Concomitant
Diabetic Coma Other Serious 4/19/2008 49 Female 9/22/2011 Lawyer United States
Primary
Concomitant
Face Oedema Other Serious 88 Female 9/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Death 6/1/2008 48 Female 121 lb 9/28/2011 Lawyer United States
Primary
Concomitant
Face Oedema Other Serious 88 Female 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Face Oedema Other Serious 88 Female 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Face Oedema Other Serious 88 Female 10/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 1/1/2010 39 Male 10/10/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data