Amitriptyline Hcl combined with Metoprolol Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Faeces Discoloured 11/7/2005 54 Female 255 lb 1/20/2006 Consumer United States
Primary
Concomitant
Hyperhidrosis Life Threatening 48 Male 4/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Skin Discolouration Hospitalization 3/16/2006 Female 250 lb 5/5/2006 Consumer
Primary
Concomitant
Sinus Bradycardia Hospitalization 47 Female 5/3/2006 United States
Primary
Secondary
Vaginal Haemorrhage Other Serious 5/12/2006 62 Female 143 lb 6/2/2006 Physician United States
Primary
Concomitant
Skin Lesion Other Serious 1/6/2006 74 Female 5/4/2006 Consumer United States
Primary
Concomitant
Treatment Noncompliance Other Serious 2/27/2005 77 Female 5/25/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2005 Female 118 lb 4/7/2006 Physician United States
Primary
Concomitant
Dry Mouth Other Serious 3/2/2006 65 Male 206 lb 4/20/2006 United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 4/1/2006 68 Male 205 lb 6/22/2006 Consumer United States
Primary
Concomitant
Endometrial Cancer Other Serious 5/12/2006 62 Female 143 lb 8/31/2006 Physician United States
Primary
Concomitant
Endometrial Cancer Stage Ii Other Serious 5/12/2006 62 Female 143 lb 9/13/2006 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/1/2006 47 Female 9/18/2006 Pharmacist United States
Primary
Secondary
Headache 5/18/2006 76 Female 140 lb 8/23/2006 Physician United States
Primary
Concomitant
Hallucination Other Serious 7/26/2006 70 Male 208 lb 8/15/2006 Physician United States
Primary
Concomitant
Rib Fracture Other Serious 10/5/2006 76 Female 12/14/2006 Consumer Canada
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Hospitalization 5/30/2006 44 Female 150 lb 12/22/2006 Physician Germany
Primary
Concomitant
Microscopic Polyangiitis Hospitalization 10/1/2004 54 Female 212 lb 12/14/2006 Consumer United States
Primary
Concomitant
Tachycardia Required Intervention 8/1/2006 Male 8/7/2006 Pharmacist United States
Primary
Concomitant
Presyncope Hospitalization 7/5/2006 68 Male 196 lb 10/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 60 Female 182 lb 1/17/2007 Pharmacist United Kingdom
Primary
Concomitant
No Adverse Drug Effect 76 Female 1/23/2007 Consumer Canada
Primary
Concomitant
Sciatica Other Serious 10/1/2004 60 Male 194 lb 6/14/2005 United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 10/9/2006 72 Male 164 lb 12/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Death 9/11/2006 63 Male 2/22/2007 Physician Germany
Primary
Concomitant
Skin Cancer Other Serious 2/1/2006 Female 230 lb 3/1/2007 Physician United States
Primary
Concomitant
Suicide Attempt Other Serious Female 154 lb 3/15/2007 Physician Germany
Primary
Secondary
Weight Decreased Hospitalization 1/1/2003 46 Male 145 lb 3/22/2007 Physician United States
Primary
Concomitant
Gout Hospitalization 2/7/2007 Female 250 lb 4/17/2007 Pharmacist United States
Primary
Concomitant
Vomiting 4/5/2006 41 Female 4/27/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2006 Female 176 lb 4/27/2007 Physician Germany
Primary
Secondary
Concomitant
Syncope Other Serious 5/17/2006 61 Male 174 lb 5/4/2007 Physician Germany
Primary
Secondary
Concomitant
Endometrial Cancer Stage Ii Other Serious 5/12/2006 Female 143 lb 5/30/2007 Physician United States
Primary
Concomitant
Endometrial Cancer Stage Ii Other Serious 5/12/2006 Female 143 lb 5/30/2007 Physician United States
Primary
Concomitant
Endometrial Cancer Stage Ii Other Serious 5/12/2006 Female 143 lb 5/30/2007 Physician United States
Primary
Concomitant
Endometrial Cancer Stage Ii Other Serious 5/12/2006 Female 143 lb 5/30/2007 Physician United States
Primary
Concomitant
Insomnia 44 Female 150 lb 4/12/2007 Other Health Professional United States
Primary
Concomitant
Leukocytosis 5/23/2007 60 Male 169 lb 5/31/2007 Pharmacist United States
Primary
Concomitant
Procedural Hypotension Required Intervention 50 Male 6/14/2007 Physician United States
Primary
Concomitant
Sciatica 10/1/2004 60 Male 194 lb 6/25/2007 United States
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 8/29/2006 56 Female 6/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Endometrial Cancer Stage Ii Other Serious 5/12/2006 Female 143 lb 7/9/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 44 Male 8/9/2007 Other Health Professional New Zealand
Primary
Concomitant
Urethral Polyp Hospitalization 60 Female 8/6/2007 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/9/2006 67 Female 8/10/2007 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 60 Female 8/15/2007 Consumer Germany
Primary
Concomitant
Urinary Incontinence Other Serious 11/29/2006 50 Male 187 lb 9/14/2007
Primary
Concomitant
Infection Hospitalization 1/1/2007 Female 9/21/2007 Consumer Canada
Primary
Secondary
Concomitant
Epilepsy Hospitalization 5/30/2006 44 Female 150 lb 9/27/2007 Physician Germany
Primary
Concomitant
Orthostatic Hypotension Hospitalization 9/30/2007 82 Female 11/9/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Large Intestinal Haemorrhage Other Serious 8/30/2006 78 Female 186 lb 11/29/2007 Consumer United States
Primary
Concomitant
Sinus Tachycardia Other Serious 44 Male 3/7/2008
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious Female 5/8/2008 Denmark
Primary
Secondary
Visual Acuity Reduced Other Serious 4/8/2008 Male 321 lb 7/2/2008 Physician United States
Primary
Concomitant
Somnolence Other Serious 6/1/2008 Female 155 lb 7/8/2008 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/1/2008 Male 321 lb 7/10/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 8/5/2008 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 8/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 6/11/2008 Female 205 lb 8/14/2008 Other Health Professional United States
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/19/2008 Female 135 lb 8/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Subdural Haematoma Death Female 118 lb 11/14/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 12/12/2008 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 12/29/2008 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Mycosis Hospitalization 11/1/2008 69 Female 1/15/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 6/26/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 10/1/2002 36 Female 276 lb 6/26/2009 United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 10/1/2003 37 Female 225 lb 7/24/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/18/2009 69 Male 184 lb 7/28/2009 Consumer Germany
Primary
Secondary
Concomitant
Pneumonia Life Threatening 7/6/2009 Female 8/5/2009 United States
Primary
Secondary
Concomitant
Social Problem Hospitalization 1/20/2006 73 Male 163 lb 9/15/2009 United States
Primary
Concomitant
Respiratory Arrest Death 43 Female 9/22/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 43 Female 9/24/2009 Physician United States
Primary
Secondary
Pathogen Resistance Other Serious 10/5/2009 Female 134 lb 3/15/2010 Other Health Professional United States
Primary
Concomitant
Vulvovaginal Candidiasis Hospitalization 1/5/2010 Female 132 lb 3/15/2010 Other Health Professional United States
Primary
Concomitant
Pulmonary Function Test Decreased Required Intervention 3/2/2010 79 Female 178 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoxia Hospitalization 3/23/2010 75 Male 216 lb 4/6/2010 Physician Netherlands
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/15/2010 79 Female 187 lb 4/6/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/18/2009 69 Male 184 lb 4/30/2010 Consumer Germany
Primary
Secondary
Concomitant
Urticaria Life Threatening 3/10/2010 43 Female 5/19/2010 Physician Germany
Primary
Concomitant
Prostate Cancer Stage I Other Serious 6/25/2010 Physician United States
Primary
Concomitant
Stomatitis Other Serious 9/17/2007 70 Female 6/30/2010 Physician Germany
Primary
Secondary
Concomitant
Vasculitis Hospitalization 11/27/2009 69 Female 7/29/2010 Physician Germany
Primary
Secondary
Concomitant
Urticaria Life Threatening 3/10/2010 43 Female 8/2/2010 Physician Germany
Primary
Concomitant
Leukoencephalopathy Hospitalization 7/1/2010 65 Female 143 lb 8/26/2010 Physician Germany
Primary
Secondary
Concomitant
Endometrial Cancer Stage I Other Serious 5/12/2006 62 Female 143 lb 10/22/2010 Physician United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 1/1/2010 28 Male 11/5/2010 Other Health Professional Netherlands
Primary
Secondary
Vomiting Hospitalization 10/9/2008 65 Female 11/24/2010 Consumer Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/9/2008 65 Female 141 lb 11/26/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 7/1/2010 65 Female 143 lb 11/29/2010 Physician Germany
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 3/1/2008 47 Female 128 lb 2/25/2011 Lawyer United States
Primary
Secondary
Concomitant
Pain Other Serious 11/15/2004 56 Female 210 lb 3/18/2011 Consumer United States
Primary
Concomitant
Constipation 12/10/2010 69 Female 3/18/2011 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 3/8/2011 91 Male 3/18/2011 Physician United States
Primary
Concomitant
Anosmia 3/20/2011 63 Female 145 lb 4/19/2011 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious Female 291 lb 5/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 6/16/2010 67 Female 5/13/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious Female 223 lb 5/16/2011 Physician Canada
Primary
Concomitant
Rib Fracture Hospitalization 3/14/2011 69 Female 5/13/2011 Consumer United States
Primary
Concomitant
Eating Disorder Other Serious 5/22/2010 63 Female 5/13/2011 United States
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious Female 223 lb 5/17/2011 Physician Canada
Primary
Concomitant
Stomatitis Other Serious 12/1/2010 67 Female 176 lb 5/23/2011 Physician Germany
Primary
Concomitant
Cholelithiasis Hospitalization 39 Female 140 lb 5/21/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 7/27/2010 73 Female 5/24/2011 Consumer United States
Primary
Concomitant
Groin Pain Disability 4/1/2001 70 Female 118 lb 5/17/2011 Lawyer United States
Primary
Concomitant
Fall Hospitalization 12/24/2010 82 Female 201 lb 6/7/2011 Physician Germany
Primary
Concomitant
Cerebrovascular Accident Other Serious 9/1/2007 32 Female 190 lb 6/7/2011 Other Health Professional United States
Primary
Concomitant
Injection Site Erythema Other Serious 5/22/2010 63 Female 229 lb 7/13/2011 Consumer United States
Primary
Concomitant
General Physical Health Deterioration Other Serious Female 291 lb 7/12/2011 Consumer United States
Primary
Secondary
Concomitant
Oophorectomy Other Serious 1/1/2009 33 Female 209 lb 7/27/2011 Consumer Netherlands
Primary
Concomitant
Mood Swings Other Serious 1/1/2009 33 Female 209 lb 8/2/2011 Consumer Netherlands
Primary
Concomitant
Hypertension Other Serious Female 8/19/2011 Physician United States
Primary
Concomitant
Off Label Use Hospitalization 5/27/2011 14 Female 110 lb 8/11/2011 Consumer Germany
Primary
Concomitant
Pain Other Serious Male 161 lb 9/8/2011 Lawyer United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/19/2007 9/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Hypertension Death 61 Male 280 lb 9/23/2011 Pharmacist United States
Primary
Concomitant
Oophorectomy Other Serious 1/1/2009 33 Female 209 lb 10/19/2011 Consumer Netherlands
Primary
Concomitant
Cardiac Arrest Life Threatening 1/1/2011 80 Male 10/27/2011 Physician Sweden
Primary
Secondary
Concomitant
Haematoma Other Serious 4/10/2006 11/14/2011 Consumer United States
Primary
Concomitant
Lymphoma Other Serious Male 11/16/2011 Lawyer United States
Primary
Concomitant
Nausea Other Serious Female 165 lb 11/18/2011 Netherlands
Primary
Concomitant
Renal Disorder Other Serious 6/26/2009 73 Male 255 lb 12/1/2011 Consumer United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization Female 218 lb 12/27/2011 Lawyer United States
Primary
Concomitant
Exostosis Other Serious 1/1/1998 36 Female 172 lb 1/5/2012 Physician United States
Primary
Secondary
Concomitant
Intestinal Polyp Hospitalization 12/14/2011 66 Female 1/5/2012 Consumer Germany
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization Female 1/6/2012 Lawyer United States
Primary
Concomitant
Toxicity To Various Agents Death 16 Female 1/9/2012 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization 6/1/2007 68 Male 231 lb 1/11/2012 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2012 59 Female 162 lb 2/23/2012 Consumer United States
Primary
Secondary
Concomitant
Arthralgia 1/1/2012 76 Male 2/29/2012 Consumer United States
Primary
Concomitant
Foot Fracture Other Serious 10/1/2011 62 Female 2/29/2012 Consumer Canada
Primary
Concomitant
Hyperkalaemia Disability 56 Female 2/21/2012 Lawyer United States
Primary
Concomitant
Joint Range Of Motion Decreased Other Serious 2/1/2004 47 Female 128 lb 3/2/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertension Other Serious Female 3/6/2012 Physician United States
Primary
Concomitant
Hypertensive Crisis Hospitalization 10/13/2011 66 Female 3/8/2012 Physician Germany
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 2/1/2004 43 Female 128 lb 3/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pallor Hospitalization 8/1/2011 59 Female 3/13/2012 Physician Germany
Primary
Concomitant
Oedema Peripheral Other Serious Male 3/16/2012 Physician United States
Primary
Concomitant
Atrial Fibrillation Other Serious Female 3/13/2012 Consumer United States
Primary
Concomitant
Aneurysm Hospitalization 9/1/2007 32 Female 190 lb 3/19/2012 Other Health Professional United States
Primary
Concomitant
Palpitations Hospitalization 2/1/2012 47 Female 3/20/2012 Consumer United States
Primary
Concomitant
Delirium Other Serious 62 Female 3/20/2012 Physician Austria
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 5/10/2008 60 Female 155 lb 3/20/2012 Consumer United States
Primary
Concomitant
Delirium Hospitalization 9/1/2010 62 Female 3/22/2012 Physician Austria
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 77 Female 3/22/2012 Physician Canada
Primary
Secondary
Electrocardiogram Qt Prolonged Other Serious 77 Female 3/22/2012 Physician Canada
Primary
Secondary
Atrioventricular Block Complete Other Serious 77 Female 3/22/2012 Physician Canada
Primary
Secondary
Atrioventricular Block Complete Other Serious 77 Female 3/22/2012 Physician Canada
Primary
Secondary
Electrocardiogram Qt Prolonged Other Serious 77 Female 3/22/2012 Physician Canada
Primary
Secondary
Economic Problem Other Serious Female 148 lb 3/19/2012 Lawyer United States
Primary
Concomitant

Drug Data