Amitriptyline Hcl combined with Methadone Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Miosis Hospitalization 3/21/2006 63 Female 220 lb 4/21/2006 United States
Primary
Secondary
Concomitant
Shock Other Serious 2/1/2006 23 Male 170 lb 4/28/2006 Physician Thailand
Primary
Secondary
Concomitant
Shock Other Serious 2/1/2006 23 Male 170 lb 5/12/2006 Physician Thailand
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/21/2006 63 Female 220 lb 5/12/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 2/27/2005 77 Female 5/25/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Neuropathy Other Serious 1/1/2005 59 Male 236 lb 4/20/2006 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2005 61 Male 217 lb 6/14/2006 Physician United Kingdom
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased 1/1/2005 66 Female 200 lb 8/8/2006 Consumer United States
Primary
Concomitant
Lower Limb Deformity Other Serious 50 Female 160 lb 7/5/2006 United States
Primary
Concomitant
Throat Tightness Hospitalization 5/24/2006 47 Female 160 lb 8/18/2006 Pharmacist United States
Primary
Concomitant
Tooth Extraction Other Serious 5/1/2005 61 Male 217 lb 9/1/2006 Physician United Kingdom
Primary
Concomitant
Tooth Loss Other Serious 3/1/2004 60 Male 224 lb 9/1/2006 Consumer United Kingdom
Primary
Concomitant
Weight Increased Other Serious 12/1/2005 42 Female 9/1/2006 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/1/2005 42 Female 9/1/2006 United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2006 56 Male 206 lb 9/8/2006 United States
Primary
Concomitant
Neutropenia Hospitalization 2/8/2006 59 Male 225 lb 9/26/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/1/2005 42 Female 9/28/2006 Physician United States
Primary
Secondary
Concomitant
Drug Hypersensitivity Required Intervention 5/24/2006 47 Female 160 lb 8/18/2006 Pharmacist United States
Primary
Concomitant
Hepatic Failure Other Serious Female 10/17/2006 Physician United States
Primary
Concomitant
Therapy Non-responder Other Serious 10/1/2006 58 Female 168 lb 10/24/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 11/28/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/28/2006 44 Female 250 lb 11/22/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 10/1/2006 58 Female 168 lb 12/19/2006 Pharmacist United States
Primary
Concomitant
Drug Toxicity Death 29 Male 12/29/2006 Other Health Professional United States
Primary
Secondary
Fall Hospitalization 10/1/2006 Male 1/15/2007 Consumer United States
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 1/15/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 9/29/2006 Male 2/23/2007 Consumer United States
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 2/19/2007 54 Male 207 lb 2/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/6/2007 Female 261 lb 3/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Male 11/13/2006 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Other Serious 33 Female 4/4/2007 Switzerland
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/6/2007 Female 261 lb 4/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/7/2007 47 Female 261 lb 4/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 39 Female 6/29/2007
Primary
Secondary
Concomitant
Nystagmus Other Serious 7/9/2007 Physician United Kingdom
Primary
Secondary
Strabismus Other Serious 7/18/2007
Primary
Secondary
Vision Blurred Hospitalization 1/1/2005 Female 7/23/2007 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 44 Male 7/25/2007 Other Health Professional
Primary
Secondary
Strabismus Congenital Anomaly 1 7/31/2007 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 44 Male 8/9/2007 Other Health Professional New Zealand
Primary
Concomitant
Urethral Polyp Hospitalization 60 Female 8/6/2007 Physician United States
Primary
Concomitant
Multiple Drug Overdose Accidental Death 8/29/2004 32 Female 148 lb 6/7/2007 Other Health Professional United States
Primary
Secondary
Hyperkalaemia Other Serious 10/1/2004 44 Male 8/28/2007 Physician New Zealand
Primary
Concomitant
Vomiting Hospitalization 7/30/2007 36 Female 9/18/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 7/30/2007 36 Female 9/21/2007 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization 10/1/2004 44 Male 9/19/2007 Other Health Professional New Zealand
Primary
Concomitant
Vomiting Hospitalization 7/30/2007 36 Female 9/11/2007 Other Health Professional United States
Primary
Concomitant
Vision Abnormal Neonatal Other Serious 10/2/2007 Physician United Kingdom
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2005 Female 10/24/2007 Consumer United States
Primary
Concomitant
Urethral Polyp Hospitalization 7/10/2007 60 Female 10/22/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 8/13/2007 54 Female 214 lb 11/27/2007 United States
Primary
Concomitant
Pharyngolaryngeal Pain Other Serious 12/12/2007 32 Female 1/2/2008 Consumer United States
Primary
Concomitant
Rash Hospitalization 12/29/2006 69 Male 187 lb 1/10/2008 Consumer United States
Primary
Concomitant
Completed Suicide Death 1/1/2006 52 Female 1/17/2008 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 41 Male 1/18/2008 United States
Primary
Secondary
Poisoning Death 64 Female 1/21/2008 Physician United States
Primary
Secondary
Tachycardia Other Serious 1/1/2002 52 Female 150 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Death Death 1/7/2006 1/25/2008 Lawyer United States
Primary
Secondary
Respiratory Arrest Death 52 Female 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 52 Female 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 41 Male 1/22/2008 Physician United States
Primary
Secondary
Neonatal Disorder Other Serious 1/1/1994 Male 1/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 1/31/2008 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 2/15/2006 59 Male 225 lb 2/4/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 1/1/2006 64 Female 1/28/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 62 Male 1/28/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 52 Female 1/28/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 30 Female 1/28/2008 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2006 20 Male 1/28/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 30 Female 1/31/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 62 Male 2/8/2008 United States
Primary
Secondary
Completed Suicide Death 2/16/2008 Other Health Professional United States
Primary
Secondary
Sinus Tachycardia Other Serious 44 Male 3/7/2008
Primary
Secondary
Concomitant
Strabismus Other Serious 1 4/7/2008 Physician United Kingdom
Primary
Secondary
Hyperaesthesia Hospitalization 1/1/2008 27 Female 4/30/2008 Physician Italy
Primary
Concomitant
Skin Ulcer Hospitalization 12/31/2007 55 Female 5/2/2008 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 3/1/1999 23 Female 6/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 40 6/9/2008 Other Health Professional United States
Primary
Secondary
Behcet's Syndrome Other Serious 9/3/2007 Female 220 lb 6/12/2008 Consumer United Kingdom
Primary
Concomitant
Respiratory Arrest Other Serious 30 Female 6/19/2008 Physician United States
Primary
Secondary
Drug Toxicity Death 2/14/2008 Male 6/23/2008 Physician United States
Primary
Secondary
Weight Increased Other Serious 1/1/2006 Female 170 lb 7/18/2008 Consumer United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 Male 130 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2007 30 Male 8/29/2008 Physician Canada
Primary
Concomitant
Somnolence Other Serious 1/1/2007 Male 9/5/2008 Physician Canada
Primary
Concomitant
Trismus Other Serious 54 Male 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 2 Male 9/17/2008
Primary
Secondary
Trismus Other Serious 54 Male 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 12/31/2007 55 Female 9/29/2008 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 170 lb 10/20/2008 Consumer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 12/31/2007 55 Female 10/20/2008 United States
Primary
Concomitant
Oropharyngeal Pain Other Serious 1/1/2008 51 Male 10/16/2008 United States
Primary
Concomitant
Pulmonary Eosinophilia Hospitalization 6/3/2008 60 Male 170 lb 10/27/2008 Physician United States
Primary
Concomitant
Flushing 10/12/2008 Female 11/26/2008 United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2008 51 Male 377 lb 11/19/2008 United States
Primary
Concomitant
Adverse Drug Reaction Death 38 Female 1/16/2009 United States
Primary
Secondary
Adverse Drug Reaction Death 38 Female 1/20/2009 Other Health Professional United States
Primary
Secondary
Accidental Poisoning Death 1/21/2009 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/22/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 40 Male 1/23/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 48 Male 1/19/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 40 Male 1/19/2009 Physician United States
Primary
Secondary
Death Death 1/28/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 62 Female 1/22/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 40 Male 1/22/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 47 Female 1/22/2009 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2007 41 Female 2/2/2009 Pharmacist United States
Primary
Secondary
Death Death 1/1/2007 38 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2007 40 Male 2/3/2009 Pharmacist United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2007 47 Female 2/4/2009 Pharmacist United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2007 55 Male 2/4/2009 Pharmacist United States
Primary
Secondary
Respiratory Arrest Death 40 Male 3/5/2009 Physician United States
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 8/1/2002 32 Female 235 lb 6/9/2009 United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 4/1/2004 73 Female 217 lb 6/25/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 10/29/2005 48 Male 170 lb 7/23/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 45 Male 7/27/2009 Consumer United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 1/1/2009 Female 8/3/2009 Consumer United States
Primary
Concomitant
Completed Suicide Death 56 Female 1/14/2010 Physician United States
Primary
Secondary
Drug Abuse Death 30 Female 1/21/2010 United States
Primary
Secondary
Poisoning Death 27 Male 1/21/2010 United States
Primary
Secondary
Drug Abuse Death 50 Female 1/20/2010 United States
Primary
Secondary
Respiratory Arrest Death 34 Male 1/21/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 50 Female 1/25/2010 Physician United States
Primary
Secondary
Syncope Other Serious 12/5/2009 32 Male 2/12/2010 Other Health Professional France
Primary
Secondary
Vision Blurred Other Serious 1/1/2002 Female 195 lb 2/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Completed Suicide Death 56 Female 3/5/2010 Other Health Professional United States
Primary
Secondary
Vasculitis Hospitalization 1/25/2010 Male 161 lb 3/17/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Trismus Other Serious 5/1/2007 Female 3/18/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 56 Female 195 lb 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 3/16/2010 55 Female 160 lb 5/6/2010 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 8/6/2003 -1 Male 4/29/2010 Physician Ireland
Primary
Concomitant
Thrombocytopenia Hospitalization 8/12/2010 34 Male 11/10/2010 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2007 42 Female 1/13/2011 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 49 Male 257 lb 2/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/21/2011 36 Female 159 lb 6/3/2011 Other Health Professional Canada
Primary
Concomitant
Respiratory Depression Death 37 6/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Toxicity To Various Agents Other Serious 48 6/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Depression Hospitalization 24 6/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Toxicity To Various Agents Death 31 6/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Accidental Overdose Death 48 7/7/2011 Other Health Professional Australia
Primary
Secondary
Toxicity To Various Agents Death 37 7/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Arrhythmia Death 48 7/12/2011 Other Health Professional Australia
Primary
Secondary
Toxicity To Various Agents Death 48 7/12/2011 Other Health Professional Australia
Primary
Secondary
Toxicity To Various Agents Death 37 7/12/2011 Other Health Professional Australia
Primary
Secondary
Toxicity To Various Agents Other Serious 24 7/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Overdose Death 48 7/15/2011 Other Health Professional United Kingdom
Primary
Secondary

Drug Data