Amitriptyline Hcl combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Hospitalization 4/11/2001 Female 1/4/2006 New Zealand
Primary
Concomitant
Syncope Other Serious 9/1/2000 Male 1/10/2006 Physician United Kingdom
Primary
Concomitant
Death Death 12/25/2005 57 Male 235 lb 1/13/2006 Other Health Professional United States
Primary
Concomitant
Troponin Increased Hospitalization 55 Female 2/7/2006 Pharmacist United States
Primary
Secondary
Troponin Increased Hospitalization 55 2/27/2006 Denmark
Primary
Secondary
No Adverse Effect Hospitalization 1/1/2006 Male 201 lb 3/1/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/8/2004 Female 3/3/2006 Physician Germany
Primary
Secondary
Concomitant
Oesophageal Carcinoma Other Serious 56 Male 3/1/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 3/28/2006 United States
Primary
Secondary
Concomitant
Faeces Discoloured 11/7/2005 54 Female 255 lb 1/20/2006 Consumer United States
Primary
Concomitant
Psoriasis Disability 1/1/2006 Female 4/7/2006 Consumer United States
Primary
Concomitant
Skin Discolouration Hospitalization 3/16/2006 Female 250 lb 4/10/2006 Consumer
Primary
Concomitant
Oesophageal Carcinoma Other Serious 2/1/2006 56 Male 244 lb 3/28/2006 Physician United States
Primary
Secondary
Concomitant
Palpitations 12/1/2005 58 Female 216 lb 1/20/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 4/7/2006 United States
Primary
Secondary
Concomitant
Shoulder Pain Other Serious 11/10/2004 72 Female 3/29/2006 Physician United States
Primary
Concomitant
Skin Exfoliation Disability 4/15/2002 Female 4/19/2006 Physician United States
Primary
Concomitant
Skin Exfoliation Disability 1/1/2004 Female 4/27/2006 Physician United States
Primary
Concomitant
Skin Discolouration Hospitalization 3/16/2006 Female 250 lb 5/5/2006 Consumer
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 5/4/2006 Male 188 lb 5/5/2006 Other Health Professional United States
Primary
Concomitant
Fall Hospitalization 2/21/2006 74 Male 5/8/2006 United States
Primary
Secondary
Concomitant
Syncope Other Serious 4/1/2006 67 Female 5/11/2006 Consumer United States
Primary
Concomitant
Syncope Life Threatening 4/2/2006 Female 331 lb 5/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/21/2006 63 Female 220 lb 5/12/2006 United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 5/4/2006 Male 188 lb 5/19/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Dyspnoea 1/25/2006 63 Female 188 lb 4/6/2006 Other Health Professional United States
Primary
Concomitant
Shoulder Pain Other Serious 11/10/2004 72 Female 5/19/2006 Physician United States
Primary
Concomitant
Multiple Myeloma Death 10/12/2004 67 Male 250 lb 5/31/2006 Physician Canada
Primary
Concomitant
Shoulder Pain Other Serious 11/10/2004 72 Female 6/7/2006 Physician United States
Primary
Concomitant
Disease Progression Death 10/12/2004 67 Male 250 lb 6/21/2006 Physician Canada
Primary
Concomitant
Urticaria Other Serious 4/21/2005 50 Female 299 lb 5/18/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/21/2005 57 Female 251 lb 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Somnolence 2/1/2006 41 Female 242 lb 4/17/2006 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Death 4/19/2006 Female 325 lb 7/7/2006 Physician Canada
Primary
Concomitant
Weight Decreased 10/11/2005 52 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Fluid Retention 8/1/2005 62 Male 7/21/2006 Consumer United States
Primary
Concomitant
Syncope Other Serious 3/1/2000 Male 8/3/2006 Physician United Kingdom
Primary
Concomitant
Hypoglycaemia Life Threatening 6/3/2006 81 Female 7/28/2006 United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 65 Male 8/8/2006 Physician New Zealand
Primary
Secondary
Skin Ulcer Life Threatening 4/2/2006 Female 331 lb 8/24/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/8/2006 59 Male 225 lb 9/26/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 1/1/2006 Male 201 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Anterior Chamber Inflammation Female 8/23/2006 Other Health Professional United States
Primary
Concomitant
Headache 5/18/2006 76 Female 140 lb 8/23/2006 Physician United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 10/19/2006 73 Female 161 lb 11/2/2006 Pharmacist United States
Primary
Concomitant
Tachycardia Hospitalization 10/23/2006 66 Female 148 lb 11/16/2006
Primary
Concomitant
Pulmonary Oedema Hospitalization 9/12/2006 65 Female 114 lb 12/5/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Face Hospitalization 1/1/2002 50 Female 12/13/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Congestion Hospitalization 11/29/2006 Female 254 lb 1/16/2007 Physician Portugal
Primary
Concomitant
Somnolence 2/1/2006 41 Female 242 lb 10/16/2006 Consumer United States
Primary
Concomitant
Nausea 8/16/2006 51 Female 248 lb 10/16/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious Female 182 lb 3/29/2007 Pharmacist United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/20/2007 64 Male 163 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
Tachycardia Hospitalization 12/11/2006 Female 243 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
Haemorrhage Hospitalization 3/27/2006 Female 130 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/1/2005 63 Female 139 lb 4/13/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 1/1/2007 Female 6/20/2007 United Kingdom
Primary
Secondary
Concomitant
Bipolar I Disorder Hospitalization 6/8/2007 56 Female 234 lb 7/5/2007
Primary
Concomitant
Pancytopenia Life Threatening 1/1/2007 Female 9/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 7/18/2007 58 Male 9/27/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Varicella 1/1/2006 59 Female 10/26/2007 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 8/1/2007 Male 220 lb 10/25/2007 Consumer United States
Primary
Concomitant
Joint Swelling Other Serious 6/15/2007 Female 20 lb 1/21/2008 United Kingdom
Primary
Concomitant
Malaise Hospitalization 7/2/2007 Male 1/21/2008 United Kingdom
Primary
Concomitant
Splenomegaly Other Serious 73 Female 3/13/2008 Consumer Canada
Primary
Secondary
Concomitant
Rectal Haemorrhage 12/1/2007 Female 170 lb 3/15/2008 Consumer United States
Primary
Concomitant
Respiratory Tract Congestion 1/1/2007 Female 170 lb 3/15/2008 United States
Primary
Concomitant
Skeletal Injury Hospitalization 12/28/2007 51 Male 256 lb 3/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 10/22/2007 75 Female 3/25/2008 Physician United States
Primary
Concomitant
Suicide Attempt Hospitalization 5/7/2008 Female 6/13/2008 Consumer Brazil
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 1/1/2006 45 Male 6/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious Female 215 lb 6/19/2008 Consumer United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/30/2008 Female 320 lb 7/11/2008 Consumer United Kingdom
Primary
Concomitant
Nausea 52 Female 7/15/2008 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/1999 Male 7/28/2008 Physician United Kingdom
Primary
Concomitant
Pain In Extremity Hospitalization 68 Male 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombosis Hospitalization 9/1/2008 26 Female 100 lb 9/8/2008 Other Health Professional United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 1/1/2008 42 Female 190 lb 10/1/2008 United States
Primary
Concomitant
Pain Other Serious 8/1/2008 Female 10/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash 8/9/2008 56 Female 12/11/2008 Physician Canada
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/29/2008 Male 1/13/2009 United Kingdom
Primary
Concomitant
Infection Hospitalization 8/19/2007 Male 1/13/2009 United Kingdom
Primary
Concomitant
Dyskinesia Hospitalization 1/1/1998 55 Female 1/23/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 5/1/2008 66 Male 170 lb 1/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lymphoma Other Serious 10/2/2007 Female 198 lb 1/28/2009 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/1/2005 73 Female 159 lb 2/4/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Male 220 lb 4/10/2009 Physician United States
Primary
Concomitant
Rash Generalised 1/1/2009 69 Male 5/15/2009 United States
Primary
Concomitant
Malaise Other Serious 4/24/2009 Female 7/1/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2003 30 Female 236 lb 7/28/2009 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/1999 39 Male 258 lb 7/30/2009 United States
Primary
Secondary
Concomitant
Muscle Rigidity Disability 5/27/2009 52 Male 226 lb 7/31/2009 Physician United Kingdom
Primary
Concomitant
Pain Other Serious 1/1/2007 68 Male 7/28/2009 United Kingdom
Primary
Concomitant
Social Problem Hospitalization 1/20/2006 73 Male 163 lb 8/4/2009 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 74 Male 8/5/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2000 57 Female 186 lb 1/25/2010 United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/1/2008 51 Female 1/25/2010 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 11/4/2009 Female 173 lb 1/30/2010 Consumer United States
Primary
Concomitant
Intentional Self-injury Hospitalization Female 165 lb 2/12/2010 Other Health Professional Germany
Primary
Secondary
Haemorrhoidal Haemorrhage Other Serious 1/1/2009 Female 129 lb 3/11/2010 United States
Primary
Concomitant
Vomiting Hospitalization 3/1/2009 Female 174 lb 3/11/2010 Other Health Professional Canada
Primary
Concomitant
Renal Injury Other Serious Female 306 lb 3/19/2010 Consumer United States
Primary
Concomitant
Pain Other Serious 8/1/2008 Female 3/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Convulsion Hospitalization 2/9/2010 Male 141 lb 3/22/2010 Physician Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 2/1/2010 68 Female 214 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Vocal Cord Polyp Other Serious 2/17/2004 57 Female 192 lb 4/23/2010 United States
Primary
Concomitant
Suicidal Ideation Disability 8/11/2010 52 Male 252 lb 8/25/2010 Physician New Zealand
Primary
Secondary
Concomitant
Ventricular Arrhythmia Death 7/15/2010 64 Male 218 lb 8/27/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperhidrosis Male 220 lb 8/27/2010 United States
Primary
Concomitant
Skin Burning Sensation 10/12/2009 Female 8/28/2010 United States
Primary
Concomitant
Blood Glucose Increased 11/15/2009 Male 8/28/2010 United States
Primary
Concomitant
Pain 3/8/2010 42 Male 225 lb 8/28/2010 United States
Primary
Concomitant
Flushing 4/6/2010 Female 231 lb 8/28/2010 United States
Primary
Concomitant
Blood Glucose Increased Female 160 lb 8/29/2010 Consumer United States
Primary
Concomitant
Pruritus 5/1/2010 67 Female 213 lb 8/29/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/10/2006 43 Male 339 lb 8/30/2010 United States
Primary
Concomitant
Supraventricular Extrasystoles Other Serious 8/3/2006 73 Male 9/1/2010 United States
Primary
Concomitant
Chromaturia 7/5/2008 77 Male 9/9/2010 Other Health Professional United States
Primary
Concomitant
Migraine 5/2/2009 48 Female 140 lb 9/9/2010 Physician United States
Primary
Concomitant
Wheezing Other Serious 4/1/2008 56 Female 154 lb 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization Female 152 lb 9/15/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/8/2009 73 Female 200 lb 9/16/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 1/26/2005 32 Female 175 lb 9/17/2010 United States
Primary
Concomitant
Tremor Hospitalization 7/11/2010 80 Female 9/16/2010 Consumer Colombia
Primary
Concomitant
Vaginal Haemorrhage 6/1/2009 47 Female 9/17/2010 Other Health Professional United States
Primary
Concomitant
Arthritis Bacterial Hospitalization 7/19/2010 66 Male 309 lb 9/24/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 12/8/2009 66 Male 10/15/2010 Physician United Kingdom
Primary
Concomitant
Adverse Drug Reaction Hospitalization 78 Female 155 lb 10/25/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Life Threatening 9/8/2010 56 Female 315 lb 10/25/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/13/2009 52 Female 306 lb 10/21/2010 Consumer United States
Primary
Concomitant
Osteoarthritis Hospitalization 10/30/2009 10/27/2010 Physician Netherlands
Primary
Concomitant
Suicidal Ideation Disability 8/11/2010 52 Male 252 lb 10/28/2010 Physician New Zealand
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 10/6/2010 79 Male 11/1/2010 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 10/19/2010 52 Male 11/1/2010 Pharmacist United States
Primary
Concomitant
Wheezing Other Serious 4/1/2008 56 Female 154 lb 11/1/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 7/26/2010 70 Female 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2010 77 Female 11/2/2010 Consumer United States
Primary
Concomitant
Arthritis Bacterial Hospitalization 10/29/2010 54 Female 177 lb 11/3/2010 Physician Chile
Primary
Secondary
Concomitant
Wheezing Other Serious 4/1/2008 56 Female 154 lb 11/3/2010 Physician United States
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 10/30/2009 11/8/2010 Physician Netherlands
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 67 Male 215 lb 11/9/2010 Consumer
Primary
Concomitant
Diarrhoea Hospitalization 9/1/2010 54 Male 198 lb 11/12/2010 Other Health Professional Canada
Primary
Concomitant
Thrombosis Other Serious 9/1/2010 61 Male 305 lb 11/24/2010 Other Health Professional United States
Primary
Concomitant
Verbal Abuse Other Serious Female 11/29/2010 Consumer Brazil
Primary
Concomitant
Blood Creatinine Increased Hospitalization 9/1/2010 64 Female 12/2/2010 Other Health Professional Sweden
Primary
Concomitant
Skin Haemorrhage 12/22/2010 Consumer United States
Primary
Concomitant
Staphylococcal Infection 9/6/2010 12/23/2010 Consumer United States
Primary
Concomitant
Hypoglycaemia Other Serious 4/28/2010 76 Female 12/29/2010 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data