Amitriptyline Hcl combined with Metformin Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Other Serious 10/11/2005 50 Male 190 lb 1/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/11/2005 50 Male 220 lb 1/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 10/17/2005 72 Male 208 lb 12/2/2005 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/11/2005 50 Male 240 lb 2/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Peroneal Nerve Palsy Disability 1/13/2006 54 Female 2/22/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/25/2005 Female 2/24/2006 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Death 12/25/2005 57 Male 235 lb 2/24/2006 Other Health Professional United States
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 11/1/2005 84 Female 198 lb 7/28/2006 United Kingdom
Primary
Concomitant
Skin Lesion 2/1/2006 68 Male 170 lb 7/12/2006 United States
Primary
Concomitant
Muscle Twitching Other Serious 4/30/2006 75 Female 7/19/2006 United States
Primary
Concomitant
Treatment Noncompliance Other Serious 8/7/2006 56 Male 222 lb 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Life Threatening 4/2/2006 Female 331 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased 4/16/2006 64 Female 238 lb 7/19/2006 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 5/23/2006 51 Female 243 lb 7/19/2006 Physician United States
Primary
Concomitant
Radius Fracture Other Serious 8/9/2006 61 Female 8/9/2006 Czech Republic
Primary
Secondary
Concomitant
Hepatic Neoplasm Hospitalization 8/20/2006 45 Female 9/15/2006 Consumer Canada
Primary
Concomitant
Spondylolysis Other Serious 59 Male 240 lb 9/19/2006 United States
Primary
Secondary
Concomitant
Spondylolysis Other Serious 59 Male 240 lb 9/22/2006 United States
Primary
Secondary
Concomitant
Nausea Hospitalization 9/25/2006 44 Male 283 lb 9/26/2006 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 66 Female 162 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 2/3/2006 72 Female 225 lb 9/29/2006 Physician Netherlands
Primary
Concomitant
Unevaluable Event Other Serious 59 Male 240 lb 10/5/2006 United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Hospitalization 8/20/2006 45 Female 10/6/2006 Physician Canada
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 10/15/2006 62 Female 230 lb 10/16/2006 Other Health Professional United States
Primary
Concomitant
Neuropathy Other Serious 1/1/2005 Female 165 lb 10/17/2006 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 9/12/2006 65 Female 114 lb 11/1/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2005 Female 165 lb 10/31/2006 United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 10/26/2006 71 Male 11/10/2006 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 11/28/2006 Physician United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 10/26/2006 71 Male 11/17/2006 Other Health Professional Canada
Primary
Concomitant
Oesophageal Carcinoma Other Serious 9/24/2006 56 Male 244 lb 12/8/2006 Physician United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 10/26/2006 71 Male 12/15/2006 Other Health Professional Canada
Primary
Concomitant
Oesophageal Carcinoma Life Threatening 2/1/2006 Male 262 lb 12/27/2006 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 10/26/2006 Male 12/27/2006 Canada
Primary
Concomitant
Atrioventricular Block Complete Hospitalization Female 160 lb 1/4/2007 Pharmacist United States
Primary
Concomitant
Middle Insomnia 7/12/2006 82 Male 200 lb 10/11/2006 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 60 Male 235 lb 10/6/2006 Physician United States
Primary
Concomitant
Upper Respiratory Tract Congestion Hospitalization 11/29/2006 Female 251 lb 1/9/2007 Physician Portugal
Primary
Concomitant
Hepatic Neoplasm Hospitalization 8/20/2006 45 Female 1/10/2007 Physician Canada
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 5/1/2006 52 Female 200 lb 11/8/2006 Other Health Professional United States
Primary
Concomitant
Skin Lesion 2/1/2006 68 Male 170 lb 11/6/2006 United States
Primary
Concomitant
Skin Lesion 2/1/2006 68 Male 170 lb 11/6/2006 United States
Primary
Concomitant
Weight Decreased 6/1/2006 59 Female 118 lb 10/16/2006 Consumer United States
Primary
Concomitant
Thyroidectomy Other Serious 1/1/2004 66 Female 1/23/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious Female 2/2/2007 Pharmacist United Kingdom
Primary
Concomitant
Drug Effect Decreased 9/10/2006 61 Female 202 lb 10/16/2006 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Congestion Hospitalization 11/29/2006 Female 254 lb 2/6/2007 Physician Portugal
Primary
Concomitant
Thyroidectomy Other Serious 1/1/2004 66 Female 2/1/2007 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 12/14/2005 Female 201 lb 2/9/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 44 Female 2/13/2007 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 9/13/2006 71 Male 257 lb 9/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/17/2007 62 Female 239 lb 2/20/2007 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/11/2007 Female 233 lb 2/27/2007 Pharmacist United States
Primary
Concomitant
Phobia Of Driving Other Serious Male 2/27/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious Female 3/1/2007 Pharmacist United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 10/26/2006 Male 3/2/2007 Canada
Primary
Concomitant
Tachycardia Hospitalization 12/11/2006 Female 243 lb 3/5/2007 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 1/17/2007 62 Female 239 lb 3/7/2007 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 12/14/2005 Female 201 lb 3/14/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 2/1/2007 Female 213 lb 3/14/2007 Consumer United States
Primary
Concomitant
Malaise Other Serious 7/10/2006 51 Female 3/8/2007 Physician United States
Primary
Concomitant
Malaise Required Intervention 7/1/2006 51 Female 3/20/2007 Physician United States
Primary
Secondary
Concomitant
Palpitations 61 Female 229 lb 3/27/2007 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 10/13/2006 67 Female 112 lb 3/21/2007 Physician Korea, Democratic People's Republic Of
Primary
Concomitant
Sinus Tachycardia Other Serious 8/15/2006 56 Female 137 lb 3/29/2007 Physician United Kingdom
Primary
Concomitant
Rash Other Serious 1/1/2007 46 Male 243 lb 4/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 10/16/2006 63 Female 239 lb 3/29/2007 Physician United States
Primary
Concomitant
Chest Pain Other Serious 8/15/2006 Female 137 lb 4/10/2007 Physician United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 11/15/2003 Female 4/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence 11/14/2006 65 Female 170 lb 1/12/2007 Consumer United States
Primary
Concomitant
Somnolence Other Serious 1/1/2007 Male 4/24/2007 Consumer United Kingdom
Primary
Concomitant
Fall Hospitalization 3/27/2007 86 Female 4/19/2007 United Kingdom
Primary
Concomitant
Pyelonephritis Hospitalization 6/1/2006 25 Female 5/3/2007 Consumer United States
Primary
Concomitant
Hypoglycaemia Life Threatening 6/3/2006 81 Female 5/23/2007 Other Health Professional France
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 6/3/2006 81 Female 5/18/2007 Physician Denmark
Primary
Concomitant
Tachycardia Hospitalization 10/18/2006 66 Female 148 lb 5/29/2007
Primary
Concomitant
Hyperaesthesia Hospitalization 62 Male 159 lb 5/24/2007 Belgium
Primary
Concomitant
Hypoglycaemia Life Threatening 6/3/2006 81 Female 5/29/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2007 62 Female 239 lb 6/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 11/1/2004 70 Female 6/13/2007 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 8/15/2006 Female 150 lb 6/13/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased 1/1/2006 55 Female 225 lb 4/10/2007 Consumer United States
Primary
Concomitant
Muscle Spasms 1/1/2006 49 Female 180 lb 4/10/2007 Consumer United States
Primary
Concomitant
Mental Disorder Hospitalization 6/9/2007 56 Female 234 lb 6/22/2007
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 8/29/2006 56 Female 6/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperaesthesia Hospitalization 1/1/2006 62 Male 6/21/2007 Other Health Professional Belgium
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 10/23/2005 68 Male 4/26/2007 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 12/11/2006 Female 243 lb 7/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Life Threatening Female 7/11/2007 United Kingdom
Primary
Concomitant
T-cell Type Acute Leukaemia Other Serious 1/26/2007 Female 205 lb 7/17/2007 United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 7/8/2007 64 Male 222 lb 7/10/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 3/27/2006 Female 130 lb 7/20/2007 Consumer United Kingdom
Primary
Concomitant
Pancytopenia Life Threatening 1/1/2007 Female 7/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 7/4/2007 Male 137 lb 7/23/2007 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 7/5/2007 Male 7/19/2007 Physician United States
Primary
Concomitant
Pancytopenia Life Threatening 1/1/2007 Female 7/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 3/27/2006 Female 130 lb 7/30/2007 Consumer United Kingdom
Primary
Concomitant
Blood Glucose Increased Other Serious 7/1/2007 Female 179 lb 8/8/2007 Consumer United States
Primary
Concomitant
Death Death 7/4/2007 Male 137 lb 8/13/2007 Physician United Kingdom
Primary
Concomitant
Drug Interaction Hospitalization 73 Male 8/13/2007
Primary
Secondary
Concomitant
Urinary Retention Other Serious 6/7/2007 Female 8/14/2007 Consumer United States
Primary
Concomitant
Bipolar I Disorder Hospitalization 6/8/2007 56 Female 234 lb 8/23/2007
Primary
Concomitant
Drug Withdrawal Syndrome Other Serious 8/1/2007 52 Male 8/24/2007 Physician United States
Primary
Concomitant
Vision Blurred 10/1/2006 55 Female 7/11/2007 Consumer United States
Primary
Concomitant
Vomiting 4/19/2007 54 Male 7/11/2007 Consumer United States
Primary
Concomitant
Sudden Death Death 8/18/2007 70 Female 101 lb 9/7/2007 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Sudden Death Death 8/18/2007 70 Female 101 lb 9/12/2007 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 1/1/2007 73 Female 9/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Hyperhidrosis Other Serious 7/1/2007 56 Female 198 lb 9/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 1/1/2007 73 Female 154 lb 9/21/2007 United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/21/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 73 Female 9/15/2007 United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/18/2006 66 Female 148 lb 10/1/2007
Primary
Concomitant
Family Stress Hospitalization 6/8/2007 56 Female 234 lb 10/2/2007
Primary
Concomitant
Pain In Extremity Other Serious 5/1/2007 68 Male 198 lb 10/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Pain Hospitalization 4/1/2007 Female 203 lb 10/12/2007 Consumer United States
Primary
Concomitant
Initial Insomnia 8/13/2007 75 Female 180 lb 10/5/2007 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 5/1/2007 68 Male 198 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/18/2007 Male 11/1/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2005 67 Female 11/12/2007 Consumer United States
Primary
Concomitant
Knee Operation Hospitalization 3/28/2007 38 Female 264 lb 11/15/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 10/25/2007 40 Female 240 lb 11/8/2007 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/17/2004 57 Female 171 lb 11/26/2007 Physician United States
Primary
Concomitant
Vision Blurred 10/1/2006 55 Female 10/9/2007 Consumer United States
Primary
Concomitant
Death Death 78 Female 12/10/2007 United Kingdom
Primary
Concomitant
Malaise Life Threatening 68 Female 132 lb 12/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Impaired Driving Ability Other Serious 47 Male 1/2/2008 Consumer Germany
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/1999 Male 1/8/2008 Physician United Kingdom
Primary
Concomitant
Orthostatic Hypotension Hospitalization 12/28/2007 51 Male 300 lb 1/11/2008 Consumer United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 11/8/2007 Female 193 lb 1/15/2008 Physician United States
Primary
Secondary
Concomitant
Heart Rate Irregular Other Serious 1/1/2004 Female 220 lb 1/17/2008 Consumer United States
Primary
Secondary
Concomitant
Somnolence Other Serious 52 Female 1/23/2008
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 11/25/2007 59 Male 260 lb 1/25/2008 Consumer United Kingdom
Primary
Concomitant
Cholelithiasis Hospitalization 10/30/2007 49 Female 187 lb 1/18/2008 Physician United States
Primary
Secondary
Concomitant
Unintended Pregnancy Other Serious 8/1/2005 Female 97 lb 1/29/2008 Consumer Brazil
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 11/1/2007 Female 295 lb 1/29/2008 Physician United States
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Hospitalization 2/15/2006 59 Male 225 lb 2/4/2008 Physician United States
Primary
Secondary
Concomitant
Skeletal Injury Hospitalization 12/28/2007 51 Male 300 lb 2/4/2008 Consumer United Kingdom
Primary
Concomitant
Oesophageal Pain Other Serious 1/29/2008 Male 250 lb 2/5/2008 Pharmacist United States
Primary
Concomitant
Haematospermia Other Serious 1/1/2008 Male 227 lb 2/15/2008 Consumer United States
Primary
Concomitant
Heart Rate Irregular Other Serious 1/1/2004 Female 220 lb 2/20/2008 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/17/2004 57 Female 171 lb 2/22/2008 Other Health Professional United States
Primary
Concomitant
Unintended Pregnancy Other Serious 1/1/2007 Female 97 lb 2/22/2008 Consumer Brazil
Primary
Concomitant
Weight Decreased Hospitalization 10/1/2006 Female 174 lb 2/22/2008 Consumer United States
Primary
Concomitant
Malaise Life Threatening 68 Female 132 lb 2/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lactic Acidosis Life Threatening 68 Female 2/20/2008 United Kingdom
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 2/12/2008 79 Female 3/5/2008 Other Health Professional Germany
Primary
Concomitant
Peripheral Ischaemia Death 2/12/2008 79 Female 139 lb 3/3/2008 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data