Amitriptyline Hcl combined with Hydromorphone Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Suicide Attempt Other Serious 12/5/2005 34 Female 1/10/2006 Other Health Professional United States
Primary
Secondary
Osteonecrosis Hospitalization 11/25/2005 63 Male 2/21/2006 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 12/1/2005 43 Female 137 lb 4/26/2006 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/21/2005 57 Female 251 lb 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization Female 149 lb 6/30/2006 Consumer United States
Primary
Concomitant
Drug Toxicity Death 35 Male 8/25/2006 Canada
Primary
Secondary
Malignant Neoplasm Progression Other Serious 8/20/2006 8 Female 68 lb 9/19/2006 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Required Intervention 8/1/2006 Male 8/7/2006 Pharmacist United States
Primary
Concomitant
Spinal Fusion Surgery Hospitalization 10/18/2006 56 Male 135 lb 3/8/2007 Consumer United States
Primary
Concomitant
Thymus Enlargement Hospitalization 1/1/2005 Female 118 lb 3/16/2007 Physician Canada
Primary
Concomitant
Thymus Enlargement Hospitalization 1/1/2005 Female 118 lb 4/2/2007 Physician Canada
Primary
Concomitant
Urticaria Other Serious 1/1/2006 Female 4/16/2007 Consumer Canada
Primary
Secondary
White Blood Cell Count Increased Hospitalization 3/8/2007 50 Female 4/23/2007 Consumer Canada
Primary
Secondary
Concomitant
Confusional State Hospitalization 4/21/2007 Female 8/23/2007 Canada
Primary
Concomitant
Multiple Drug Overdose Accidental Death 8/29/2004 32 Female 148 lb 6/7/2007 Other Health Professional United States
Primary
Secondary
Confusional State Hospitalization 4/21/2007 Female 9/26/2007 Canada
Primary
Concomitant
Weight Decreased Other Serious 1/1/2000 71 Female 10/20/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Analysis Increased Other Serious 1/1/2000 71 Female 11/22/2007 United States
Primary
Secondary
Concomitant
Death Hospitalization 3/13/2008 84 Female 3/19/2008 Physician Canada
Primary
Concomitant
Surgery Other Serious 4/1/2008 Male 5/16/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Substance Abuse Death 47 Female 6/11/2008 Canada
Primary
Secondary
Gingival Hyperplasia Hospitalization 7/20/2008 Male 8/7/2008 Physician United States
Primary
Secondary
Concomitant
Gingival Hyperplasia Hospitalization 7/20/2008 Male 8/21/2008 Physician United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 60 Male 9/5/2008 Other Health Professional Belgium
Primary
Concomitant
Interacting
Death Death Female 9/30/2008 Consumer United States
Primary
Concomitant
Somnolence Life Threatening 60 Male 10/8/2008 Other Health Professional United States
Primary
Secondary
Thrombocytopenia Other Serious 1/1/2008 Male 10/10/2008 Pharmacist Canada
Primary
Concomitant
Gingival Hyperplasia 7/20/2008 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Treatment Failure Other Serious 1/1/2008 Male 12/2/2008 Physician Canada
Primary
Concomitant
Drug Ineffective Other Serious 21 Male 12/24/2008
Primary
Secondary
Wrong Technique In Drug Usage Process 12/1/2008 37 Female 1/16/2009 Pharmacist Canada
Primary
Concomitant
Urticaria Hospitalization 15 Male 101 lb 1/23/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Neoplasm Progression Death Male 122 lb 2/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Death 49 Female 2/6/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 Male 2/19/2009 Physician Canada
Primary
Concomitant
Bone Pain Other Serious 1/8/2009 Male 185 lb 3/20/2009 Germany
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/8/2009 Male 187 lb 4/1/2009 Germany
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/8/2009 Male 187 lb 4/3/2009 Germany
Primary
Secondary
Concomitant
Drug Toxicity Death 49 Female 4/9/2009 Consumer United States
Primary
Secondary
Concomitant
Surgery Other Serious 1/8/2009 Male 185 lb 4/14/2009 Germany
Primary
Secondary
Concomitant
Prosthesis Implantation Other Serious 1/8/2009 Male 161 lb 5/28/2009 Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/4/2003 29 Male 265 lb 7/23/2009 United States
Primary
Concomitant
Tooth Disorder Other Serious 3/24/2009 53 Male 7/27/2009 Physician Canada
Primary
Concomitant
Respiratory Failure Other Serious 12/1/2005 43 7/28/2009 Other Health Professional Germany
Primary
Concomitant
Interacting
Type 2 Diabetes Mellitus Other Serious 2/1/2003 30 Female 236 lb 7/28/2009 United States
Primary
Concomitant
Hyperammonaemia Other Serious 3/20/2009 Female 120 lb 8/6/2009 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Required Intervention 49 Female 11/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Malnutrition Hospitalization 9/5/2009 50 Female 90 lb 11/25/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2009 Female 3/1/2010 Canada
Primary
Concomitant
Pyrexia Other Serious 1/1/2009 Female 3/2/2010 Canada
Primary
Concomitant
Drug Toxicity Other Serious 61 Female 3/8/2010 Other Health Professional Canada
Primary
Concomitant
Drug Toxicity Other Serious 61 Female 3/8/2010 Other Health Professional Canada
Primary
Concomitant
Skin Discolouration Other Serious 1/1/2009 Female 3/12/2010 Canada
Primary
Concomitant
Trismus Other Serious 5/1/2007 Female 3/18/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 3/14/2006 Female 3/26/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2007 Female 3/26/2010 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 61 Female 3/23/2010 Other Health Professional Canada
Primary
Concomitant
Dermatitis Exfoliative Other Serious 4/22/2010 53 Female 7/6/2010 Physician Italy
Primary
Secondary
Concomitant
Gastric Cancer Stage Iii Life Threatening 2/1/2010 59 Female 7/16/2010 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Life Threatening 11/1/2009 59 Female 7/21/2010 Physician Germany
Primary
Concomitant
Dermatitis Exfoliative Other Serious 4/22/2010 53 Female 7/21/2010 Physician Italy
Primary
Secondary
Concomitant
Gastric Cancer Life Threatening 2/1/2010 59 Female 7/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Post Procedural Pneumonia Other Serious 2/1/2010 59 Female 7/22/2010 Physician Germany
Primary
Concomitant
Pneumonia Aspiration Life Threatening 7/8/2010 67 Female 8/4/2010 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 7/8/2010 67 Female 8/10/2010 Physician Germany
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 10/13/2010 Female 10/27/2010 Consumer Canada
Primary
Concomitant
Skin Test Positive Required Intervention 76 Female 10/25/2010 Physician Canada
Primary
Concomitant
Vasculitis Hospitalization 10/8/2010 55 Male 157 lb 12/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/1/2007 42 Female 1/13/2011 Other Health Professional United States
Primary
Concomitant
Dysphagia Hospitalization 12/25/2010 82 Female 95 lb 2/7/2011 Other Health Professional Canada
Primary
Concomitant
Local Swelling Hospitalization 12/25/2010 82 Female 95 lb 2/8/2011 Other Health Professional Canada
Primary
Concomitant
Death Death 42 Female 3/14/2011 Physician United States
Primary
Secondary
Biliary Tract Disorder Hospitalization 12/5/2010 51 Female 5/17/2011 Physician United States
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 3/14/2006 50 Female 5/20/2011 Other Health Professional United States
Primary
Concomitant
Hypertension Hospitalization 12/3/2010 45 Female 313 lb 5/25/2011 Physician Germany
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 4/26/2011 72 Female 141 lb 5/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Hospitalization 4/26/2011 72 Female 141 lb 6/1/2011 Physician Canada
Primary
Secondary
Concomitant
Fluid Retention Other Serious 3/14/2006 50 Female 6/23/2011 Lawyer United States
Primary
Concomitant
Anaemia Of Chronic Disease Other Serious 3/17/2004 56 Female 140 lb 6/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 70 Female 6/20/2011 United States
Primary
Concomitant
Fungaemia Hospitalization 10/8/2010 55 Male 157 lb 7/7/2011 Consumer United States
Primary
Secondary
Concomitant
Hallucination Other Serious 1/1/2010 40 Male 7/11/2011 Physician Hungary
Primary
Secondary
Fungaemia Hospitalization 10/8/2010 55 Male 157 lb 7/18/2011 Consumer United States
Primary
Secondary
Concomitant
Hypertension Hospitalization 12/3/2010 45 Female 313 lb 7/19/2011 Physician Germany
Primary
Concomitant
Pleural Effusion Death 3/17/2004 56 Female 140 lb 7/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 3/14/2006 50 Female 7/28/2011 Lawyer United States
Primary
Concomitant
Drug Ineffective Other Serious 17 Male 8/1/2011 Physician United States
Primary
Secondary
Hypertension Hospitalization 12/3/2010 45 Female 313 lb 8/5/2011 Physician Germany
Primary
Concomitant
Respiratory Failure Hospitalization Female 237 lb 8/9/2011 Physician United States
Primary
Concomitant
Cervical Dysplasia Other Serious 5/1/2007 42 Female 8/22/2011 Lawyer United States
Primary
Concomitant
Vasculitis Hospitalization 10/8/2010 55 Male 157 lb 8/30/2011 Consumer United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 7/8/2010 67 Female 9/12/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Coma Life Threatening 7/8/2010 67 Female 9/13/2011 Physician Germany
Primary
Secondary
Concomitant
Diverticulitis Other Serious 5/1/2007 42 Female 9/13/2011 Other Health Professional United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 7/8/2010 67 Female 9/8/2011 Physician Germany
Primary
Secondary
Concomitant
Hallucination Hospitalization 1/1/2010 40 Male 9/30/2011 Physician Hungary
Primary
Secondary
Neoplasm Progression Other Serious 1/1/2010 40 Male 10/19/2011 Physician Hungary
Primary
Secondary
Cystitis Haemorrhagic Hospitalization 4/26/2011 72 Female 141 lb 10/20/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 3/3/2007 41 Female 176 lb 10/24/2011 Physician United States
Primary
Concomitant
Lung Infection Hospitalization 10/14/2011 78 Male 214 lb 11/1/2011 Physician United States
Primary
Secondary
Concomitant
Economic Problem Other Serious 70 Female 220 lb 11/2/2011 Lawyer United States
Primary
Concomitant
Therapeutic Response Decreased Death 1/1/2010 40 Male 11/7/2011 Physician Hungary
Primary
Secondary
Hypotension Hospitalization 1/1/2010 40 Male 11/8/2011 Physician Hungary
Primary
Secondary
Coma Death 1/1/2010 40 Male 11/14/2011 Physician Hungary
Primary
Secondary
Sepsis Hospitalization 10/14/2011 78 Male 218 lb 11/14/2011 Physician United States
Primary
Secondary
Concomitant
Disorientation Other Serious 1/1/2010 40 Male 11/18/2011 Physician Hungary
Primary
Secondary
Mucosal Inflammation Other Serious 10/24/2011 73 Male 11/23/2011 Physician Spain
Primary
Concomitant
Cardiovascular Disorder Other Serious 10/13/2011 62 Female 104 lb 11/23/2011 Physician Germany
Primary
Concomitant
Convulsion Hospitalization 1/1/2010 40 Male 12/8/2011 Physician Hungary
Primary
Secondary
Application Site Pain Other Serious 10/13/2011 62 Female 104 lb 12/8/2011 Physician Germany
Primary
Concomitant
Large Intestinal Ulcer Other Serious 12/11/2009 53 Female 145 lb 12/13/2011 Lawyer United States
Primary
Concomitant
Mental Status Changes Other Serious 9/16/2011 54 Female 243 lb 1/2/2012 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Death 9/26/2011 52 Female 123 lb 1/4/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Polymyalgia Rheumatica Hospitalization 7/29/2008 53 Female 166 lb 11/17/2011 Lawyer United States
Primary
Concomitant
Death Death Female 224 lb 1/18/2012 Pharmacist United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 61 Female 1/13/2012 Other Health Professional Canada
Primary
Concomitant
Unresponsive To Stimuli Death 38 Female 1/19/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperglobulinaemia Other Serious 5/1/2007 42 Female 1/30/2012 Lawyer United States
Primary
Concomitant
Nausea 1/24/2011 44 Male 1/27/2012 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 11/1/2008 17 Female 135 lb 2/2/2012 Lawyer United States
Primary
Secondary
Concomitant
Completed Suicide Death 52 Female 2/15/2012 Physician United States
Primary
Secondary
Death Death 1/1/2009 42 Female 2/15/2012 Physician United States
Primary
Secondary
Death Death 42 Female 2/15/2012 Other Health Professional United States
Primary
Secondary
Dyspepsia Other Serious 5/1/2007 42 Female 2/27/2012 Consumer United States
Primary
Concomitant
Drug Abuse Death 52 Female 121 lb 2/22/2012 Physician United States
Primary
Secondary
Concomitant
Death Death Female 224 lb 3/2/2012 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Other Serious 62 Female 3/15/2012 Other Health Professional Austria
Primary
Secondary
Concomitant
Delirium Other Serious 62 Female 3/20/2012 Physician Austria
Primary
Secondary
Concomitant
Delirium Hospitalization 9/1/2010 62 Female 3/22/2012 Physician Austria
Primary
Secondary
Concomitant
Sepsis Other Serious 62 Female 3/19/2012 Other Health Professional
Primary
Secondary
Concomitant
Hallucination Hospitalization 3/8/2012 44 Female 179 lb 4/3/2012 Other Health Professional Canada
Primary
Concomitant
Renal Failure Other Serious 4/1/2010 47 Female 130 lb 4/13/2012 Lawyer United States
Primary
Concomitant
Metastases To Lymph Nodes Hospitalization 2/1/2010 59 Female 4/26/2012 Consumer Germany
Primary
Secondary
Concomitant
Metastatic Gastric Cancer Life Threatening 2/1/2010 59 Female 4/26/2012 Germany
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 11/1/2009 59 Female 5/1/2012 Physician Germany
Primary
Concomitant
Visual Acuity Reduced Death 3/17/2004 56 Female 140 lb 5/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 62 Female 5/9/2012 Other Health Professional Austria
Primary
Secondary
Concomitant
Delirium Other Serious 1/1/2010 62 Female 5/14/2012 Physician Austria
Primary
Secondary
Concomitant
Delirium Other Serious 1/1/2010 62 Female 5/14/2012 Physician Austria
Primary
Secondary
Concomitant
Delirium Other Serious 1/1/2010 62 Female 5/14/2012 Physician Austria
Primary
Secondary
Concomitant
Delirium Other Serious 1/1/2010 62 Female 5/14/2012 Physician Austria
Primary
Secondary
Concomitant
Delirium Other Serious 1/1/2010 62 Female 5/14/2012 Physician Austria
Primary
Secondary
Concomitant
Delirium Other Serious 1/1/2010 62 Female 5/14/2012 Physician Austria
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2011 68 Male 5/26/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2010 62 Female 5/17/2012 Physician Austria
Primary
Secondary
Concomitant
Hemiparesis Other Serious 62 Female 5/18/2012 Other Health Professional Austria
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 5/24/2012 Physician Austria
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/13/2012 70 Male 188 lb 5/24/2012 Physician Australia
Primary
Secondary
Concomitant
Sepsis Other Serious 62 Female 5/29/2012 Other Health Professional Israel
Primary
Secondary
Concomitant
Delirium Hospitalization 62 Female 5/29/2012 Physician Austria
Primary
Secondary

Drug Data