Amitriptyline combined with Clonazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Drug Tolerance Increased Other Serious Female 162 lb 3/14/2006 Other Health Professional United States
Primary
Concomitant
Intentional Overdose Life Threatening 44 Male 3/24/2006 Pharmacist United States
Primary
Secondary
Ear Operation Other Serious 12/1/2008 Female 238 lb 12/23/2008 Other Health Professional Canada
Primary
Concomitant
Respiratory Arrest Death 1/1/2007 52 Female 12/24/2008 Physician United States
Primary
Secondary
Respiratory Acidosis Hospitalization 11/1/2008 1/15/2009 Physician Switzerland
Primary
Secondary
Concomitant
Respiratory Acidosis Hospitalization 11/1/2008 1/22/2009 Physician Switzerland
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 8/5/2004 19 Male 2/20/2009 United States
Primary
Concomitant
Tardive Dyskinesia Disability 69 Female 2/23/2009 United States
Primary
Concomitant
Product Quality Issue 2/23/2008 55 Female 2/27/2009 Consumer United States
Primary
Concomitant
Psychotic Disorder Hospitalization 12/20/2008 52 Female 3/18/2009 Physician United States
Primary
Concomitant
Completed Suicide Death 40 Male 3/20/2009 Physician United States
Primary
Secondary
Completed Suicide Death 52 Female 3/20/2009 Physician United States
Primary
Secondary
Pyrexia Hospitalization 3/19/2009 Female 139 lb 3/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 5/15/2005 36 Female 167 lb 4/7/2009 United States
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/2009 Female 119 lb 5/4/2009 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 1/1/2009 Female 119 lb 5/22/2009 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 1/1/2009 Female 119 lb 6/4/2009 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 11/1/2007 Female 6/30/2009 Consumer United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 20 7/1/2009 Physician Czech Republic
Primary
Secondary
Product Quality Issue Death 11/15/2007 Female 150 lb 7/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 5/19/2005 43 Male 108 lb 7/15/2009 United States
Primary
Secondary
Concomitant
Haematemesis Other Serious 7/10/2009 28 Female 7/20/2009 Consumer Brazil
Primary
Concomitant
Pancreatitis Other Serious 2/14/2002 35 Male 242 lb 7/21/2009 United States
Primary
Secondary
Concomitant
Diabetic Nephropathy Other Serious 1/1/1999 48 Female 202 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Ear Operation Other Serious 12/1/2008 Female 238 lb 7/23/2009 Other Health Professional Canada
Primary
Concomitant
Tongue Oedema Other Serious 1/1/2009 7/24/2009 Physician Thailand
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2000 47 Female 152 lb 8/13/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 5/9/2006 49 Female 210 lb 8/13/2009 United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 6/16/2009 53 Female 7/22/2009 Other Health Professional United States
Primary
Concomitant
Tinnitus Disability 10/1/2004 69 Female 117 lb 8/11/2009 United States
Primary
Concomitant
Hypothermia Hospitalization 1/1/2006 69 Male 8/18/2009 Other Health Professional France
Primary
Secondary
Concomitant
Viral Infection Disability 1/1/2000 69 Female 117 lb 8/18/2009 United States
Primary
Concomitant
Flushing 7/6/2009 Female 200 lb 8/23/2009 Physician United States
Primary
Concomitant
Piloerection Other Serious 7/11/2009 30 8/24/2009 Physician Argentina
Primary
Concomitant
Suicide Attempt Other Serious 2/1/2007 Female 140 lb 8/25/2009 Consumer United States
Primary
Concomitant
Pulmonary Congestion Hospitalization 7/10/2007 45 Female 8/28/2009 United States
Primary
Concomitant
Serotonin Syndrome Other Serious 6/16/2009 53 Female 8/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Disability 1/1/2000 69 Female 117 lb 8/28/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 1/1/2008 Female 140 lb 9/3/2009 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 9/4/2009 Consumer United States
Primary
Concomitant
Nausea Other Serious 4/1/2009 65 Female 186 lb 9/9/2009 Physician Canada
Primary
Concomitant
Nocturia Other Serious 8/19/2009 56 9/9/2009 Consumer Brazil
Primary
Concomitant
Rectal Haemorrhage 12/1/2007 Female 170 lb 9/12/2009 Consumer United States
Primary
Concomitant
Tardive Dyskinesia Disability 1/1/2000 69 Female 117 lb 9/10/2009 United States
Primary
Concomitant
Oedema Peripheral Female 200 lb 9/19/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/4/2005 48 Female 245 lb 9/21/2009 United States
Primary
Concomitant
Visual Field Defect Disability 1/1/2000 69 Female 117 lb 9/17/2009 United States
Primary
Concomitant
Urinary Tract Infection 5/25/2001 35 Female 100 lb 9/23/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2005 34 Female 249 lb 9/23/2009 United States
Primary
Concomitant
Pancreatitis Other Serious Female 158 lb 9/23/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection 12/7/2005 37 Male 252 lb 9/23/2009 United States
Primary
Concomitant
Spinal Osteoarthritis 1/1/2000 38 Male 9/23/2009 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/2004 44 Female 132 lb 9/23/2009 United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 6/24/2002 46 Female 180 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 5/1/2003 45 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 10/5/2004 41 Female 180 lb 9/24/2009 Other Health Professional United States
Primary
Concomitant
Vulvovaginal Candidiasis 12/1/2006 36 Female 227 lb 9/24/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/20/2004 46 Male 234 lb 10/5/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 9/1/2009 Female 172 lb 10/8/2009 Consumer United States
Primary
Concomitant
Wheezing Disability 1/1/2000 69 Female 117 lb 10/6/2009 United States
Primary
Concomitant
Weight Increased Other Serious 5/1/2002 56 10/9/2009 Consumer Brazil
Primary
Secondary
Concomitant
Skin Lesion Hospitalization 5/9/2006 69 10/13/2009 Physician France
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 35 Female 235 lb 10/14/2009 United States
Primary
Concomitant
Suicide Attempt Other Serious 2/1/2007 Female 140 lb 10/14/2009 Consumer United States
Primary
Concomitant
Sedation Other Serious 2/1/2009 36 10/14/2009 Physician Brazil
Primary
Secondary
Concomitant
Wheezing Disability 1/1/2000 69 Female 117 lb 10/9/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2008 52 Female 10/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/13/2008 52 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Disability 1/1/2000 69 Female 117 lb 10/21/2009 United States
Primary
Concomitant
Weight Increased Other Serious 5/1/2002 56 Male 216 lb 11/3/2009 Physician Brazil
Primary
Secondary
Concomitant
Somnambulism 10/1/2008 Male 165 lb 11/5/2009 Physician United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 8/25/2009 51 Male 225 lb 10/30/2009 Pharmacist United States
Primary
Secondary
Concomitant
Vocal Cord Inflammation Disability 1/1/2000 69 Female 117 lb 11/16/2009 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/27/2007 Female 150 lb 12/1/2009 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 11/17/2009 47 Female 12/3/2009 Physician United States
Primary
Concomitant
Visual Impairment Hospitalization 59 Female 12/11/2009 United States
Primary
Concomitant
Wheezing Disability 1/1/2000 69 Female 117 lb 12/15/2009 United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2008 63 Male 1/15/2010 Physician United States
Primary
Secondary
Weight Decreased Other Serious 10/19/1999 Female 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/21/2010 Female 218 lb 3/8/2010 Consumer United States
Primary
Concomitant
Death Death 1/1/2008 33 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Fatigue 8/1/2009 Female 3/16/2010 Physician United States
Primary
Concomitant
Urinary Hesitation Other Serious 1/1/2008 Female 269 lb 3/31/2010 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Death 11/15/2007 Female 150 lb 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/1/2002 54 Male 216 lb 4/13/2010 Physician Brazil
Primary
Secondary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 4/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 4/22/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 4/28/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/3/2010 United States
Primary
Concomitant
Treatment Failure Disability 2/24/2010 38 Female 213 lb 5/5/2010 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/21/2010 United States
Primary
Concomitant
Tremor Hospitalization 1/1/2010 Male 5/25/2010 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2009 39 Female 198 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 6/2/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 51 Male 226 lb 5/26/2010 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective 1/1/2010 60 Male 189 lb 6/9/2010 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 58 Male 6/11/2010 Other Health Professional France
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/1/2008 52 Female 6/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 6/15/2010 United States
Primary
Concomitant
Syncope Other Serious 58 Male 6/15/2010 Other Health Professional France
Primary
Secondary
Syncope Other Serious 58 Male 6/15/2010 Other Health Professional France
Primary
Secondary
Syncope Other Serious 58 Male 6/16/2010 Other Health Professional France
Primary
Secondary
White Blood Cell Count Decreased Other Serious 52 Female 6/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 58 Male 6/25/2010 Other Health Professional France
Primary
Secondary
Sleep Disorder Hospitalization 69 Male 6/18/2010 Other Health Professional France
Primary
Secondary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 7/5/2010 United States
Primary
Secondary
Concomitant
Sedation Death 11/15/2007 50 Female 150 lb 7/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Oral 1/3/2007 60 Male 170 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Piloerection Other Serious 7/11/2009 30 Male 170 lb 9/16/2010 Physician Argentina
Primary
Concomitant
Pyrexia Other Serious 2/21/2010 32 Female 218 lb 9/16/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 10/19/1999 64 Female 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/29/2010 46 Male 247 lb 10/8/2010 Consumer United States
Primary
Concomitant
Weight Increased 48 Female 195 lb 10/13/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 7/30/2010 90 Female 103 lb 10/11/2010 Physician Canada
Primary
Concomitant
Subdural Haemorrhage Hospitalization 9/13/2010 40 Female 12/3/2010 Other Health Professional Czech Republic
Primary
Concomitant
Pain Disability 8/1/2010 39 Male 12/6/2010 Consumer Brazil
Primary
Concomitant
Cystitis 11/9/2010 48 Female 12/7/2010 Pharmacist United States
Primary
Concomitant
Piloerection Other Serious 7/11/2009 30 8/24/2009 Physician Argentina
Primary
Concomitant
Suicide Attempt Other Serious 2/1/2007 35 Female 140 lb 10/14/2009 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 2/21/2010 32 Female 218 lb 3/8/2010 Consumer United States
Primary
Concomitant
Injection Site Pruritus 11/16/2009 12/19/2010 Consumer United States
Primary
Concomitant
Nail Disorder Female 12/21/2010 Physician United States
Primary
Concomitant
Diarrhoea Other Serious 10/1/2004 51 Female 202 lb 1/4/2011 Consumer United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 9/8/2010 49 Female 161 lb 12/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Other Serious 10/1/2009 62 Female 241 lb 1/4/2011 Consumer United States
Primary
Concomitant
Cardio-respiratory Arrest Death 42 Female 1/4/2011 Physician United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 1/1/2009 42 Female 1/7/2011 Physician United States
Primary
Secondary
Concomitant
Nail Disorder Female 1/7/2011 Physician United States
Primary
Concomitant
Death Death 41 Female 1/13/2011 Physician United States
Primary
Secondary
Diabetic Nephropathy Hospitalization 10/1/2004 51 Female 202 lb 1/18/2011 Lawyer United States
Primary
Concomitant
Death Death 39 Female 1/19/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 49 Female 1/19/2011 Physician United States
Primary
Secondary
Pyrexia Other Serious 7/13/2010 55 Female 1/19/2011 Physician Canada
Primary
Concomitant
Completed Suicide Death 41 Female 1/19/2011 Physician United States
Primary
Secondary
Incorrect Route Of Drug Administration Death 42 Female 1/19/2011 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 41 Female 1/21/2011 Physician United States
Primary
Secondary
Allergic Respiratory Symptom Other Serious 8/1/2010 63 Female 134 lb 1/25/2011 Consumer Argentina
Primary
Concomitant
Cardiac Arrest Death 1/1/2009 41 Female 1/27/2011 Physician United States
Primary
Secondary
Emotional Disorder Other Serious 8/1/2010 63 Female 134 lb 2/22/2011 Consumer Argentina
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/29/2006 24 Female 230 lb 2/23/2011 Lawyer United States
Primary
Secondary
Concomitant
Completed Suicide Death 41 Female 2/7/2011 Physician United States
Primary
Secondary
Completed Suicide Death 41 Female 3/6/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death Female 3/7/2011 Physician United States
Primary
Secondary
Gastrointestinal Disorder Hospitalization 1/1/2010 31 Female 176 lb 3/22/2011 Consumer Brazil
Primary
Concomitant
Dysuria Hospitalization 5/1/2002 54 Male 220 lb 3/22/2011 Physician Brazil
Primary
Secondary
Concomitant
Pain Male 220 lb 3/25/2011 Consumer United States
Primary
Secondary
Concomitant
Dyspepsia Other Serious 12/1/2005 39 Female 144 lb 3/28/2011 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious Female 216 lb 3/30/2011 Physician United States
Primary
Concomitant
Tachypnoea Hospitalization 61 Male 3/23/2011 Other Health Professional Netherlands
Primary
Concomitant
Pelvic Pain Other Serious 1/1/2010 58 Male 137 lb 4/11/2011 Physician Canada
Primary
Concomitant

Drug Data