Amiodarone combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Tachycardia Hospitalization 9/14/2005 57 Female 211 lb 1/12/2006 United States
Primary
Concomitant
Hyperaldosteronism Hospitalization 12/28/2004 73 Female 121 lb 2/3/2006 Consumer France
Primary
Secondary
Concomitant
Haemodialysis Other Serious 82 Female 2/13/2006 Canada
Primary
Concomitant
Thrombosis Other Serious 63 Male 230 lb 2/16/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 64 Male 2/28/2006 Israel
Primary
Concomitant
Subdural Haematoma Other Serious 1/27/2004 66 Female 2/27/2006 France
Primary
Secondary
Concomitant
Urine Colour Abnormal Hospitalization 1/28/2005 45 Male 3/27/2006 Physician Philippines
Primary
Concomitant
Vomiting Death 5/11/2005 67 Female 137 lb 4/11/2006 Physician Australia
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/4/2005 Male 2/21/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 4/27/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Maculo-papular Required Intervention 9/24/2005 76 Female 159 lb United States
Primary
Concomitant
Ocular Hyperaemia Required Intervention 4/17/2006 Male 188 lb 5/10/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 2/19/2004 40 Female 5/17/2006 Physician Japan
Primary
Concomitant
Prothrombin Time Prolonged 3/8/2006 76 Male 9/6/2006 Consumer United States
Primary
Concomitant
Myositis Life Threatening 6/1/2006 75 Male 139 lb 3/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myositis Life Threatening 6/1/2006 75 Male 139 lb 3/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Prothrombin Time Abnormal Other Serious 2/1/2007 70 Male 4/25/2007 Consumer United States
Primary
Concomitant
Rash Other Serious Female 200 lb 4/27/2007 Physician United States
Primary
Concomitant
Interacting
Oral Mucosal Blistering 5/1/2007 47 Female 7/6/2007 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 9/1/2006 62 Male 10/1/2007 Physician Germany
Primary
Secondary
Concomitant
Intra-abdominal Haematoma Other Serious 1/1/2007 58 Male 10/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 1/1/2007 Male 281 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Torsade De Pointes Other Serious 10/25/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Vasoplegia Syndrome Death 7/21/2004 48 Male 217 lb 11/1/2007 Physician United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 2/7/2008 86 Female 4/2/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 2/7/2008 86 Female 4/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 3/1/2008 50 Male 163 lb 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Urea Abnormal Hospitalization 3/17/2008 62 Male 4/16/2008 Other Health Professional France
Primary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 5/9/2008 Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2008 65 Male 5/27/2008 Consumer United States
Primary
Concomitant
Treatment Noncompliance Death 5/11/2008 Female 185 lb 5/27/2008 Other Health Professional United States
Primary
Concomitant
Malaise Hospitalization 6/5/2008 85 Female 7/28/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vertigo Hospitalization 6/5/2008 Female 7/28/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2007 73 Female 8/12/2008 Pharmacist Spain
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2007 73 Female 8/21/2008 Pharmacist Spain
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/22/2008 78 Male 8/27/2008 Other Health Professional Spain
Primary
Concomitant
Pruritus 2/5/2008 Male 220 lb 8/27/2008 Consumer United States
Primary
Concomitant
Flushing 1/1/2007 Male 8/27/2008 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/2/2007 Female 199 lb 8/29/2008 Physician United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 73 Female 166 lb 9/29/2008 United States
Primary
Concomitant
Vomiting Other Serious 11/1/2007 71 Female 2/20/2009 Lawyer United States
Primary
Concomitant
Xanthopsia Hospitalization 73 Female 166 lb 4/7/2009 United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Myositis Hospitalization 2/1/2009 66 Male 4/29/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Wound Hospitalization 54 Female 4/27/2009 Physician Belgium
Primary
Concomitant
Sepsis Hospitalization 12/19/2005 Male 295 lb 5/6/2009 Physician United States
Primary
Secondary
Concomitant
Calciphylaxis Other Serious 54 Female 5/8/2009 Belgium
Primary
Concomitant
Shock Hospitalization 2/18/2009 82 Female 5/18/2009 Physician Switzerland
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 3/2/2009 72 Female 5/26/2009 Physician Switzerland
Primary
Secondary
Concomitant
Pneumonia Other Serious 2/14/2006 Male 150 lb 5/27/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Drug Interaction Life Threatening 5/25/2009 Female 163 lb 6/24/2009 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Multiple Injuries Hospitalization 46 Male 7/13/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 73 Male 7/20/2009 Pharmacist United States
Primary
Concomitant
Visual Impairment Hospitalization 10/25/2007 73 Male 229 lb 7/15/2009 Lawyer United States
Primary
Concomitant
Vision Blurred Hospitalization 10/25/2007 73 Female 229 lb 7/17/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 73 Male 7/28/2009 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/1/2006 62 Male 8/18/2009 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 46 Male 8/13/2009 United States
Primary
Concomitant
Restless Legs Syndrome 11/1/2008 67 Male 217 lb 9/2/2009 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 8/1/2006 81 Female 9/22/2009 Physician United Kingdom
Primary
Concomitant
Hepatic Failure Death 7/27/2009 77 9/28/2009 Physician Germany
Primary
Secondary
Concomitant
Vertigo Hospitalization 74 Female 9/23/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 1/22/2008 46 Male 9/21/2009 Lawyer United States
Primary
Concomitant
Vasculitis Other Serious 7/7/2009 75 Male 9/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 86 Female 9/23/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 67 Male 9/24/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 68 Male 229 lb 9/24/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 9/22/2009 United States
Primary
Concomitant
Renal Failure Other Serious 72 10/5/2009 Physician Brazil
Primary
Concomitant
Mobility Decreased Other Serious 6/4/2006 83 Female 9/30/2009 United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 50 Male 354 lb 9/22/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Walking Disability Other Serious Male 10/9/2009 Consumer Brazil
Primary
Concomitant
Pneumonia Hospitalization 4/8/2009 90 Female 88 lb 8/31/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 46 Male 10/10/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 10/9/2009 United States
Primary
Concomitant
Pain Hospitalization 67 Male 10/9/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 1/22/2008 57 Male 10/9/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Death 7/27/2009 Male 10/20/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/1999 Male 10/15/2009 Consumer United States
Primary
Concomitant
Treatment Noncompliance Other Serious Male 10/21/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 1/22/2008 57 Male 10/16/2009 United States
Primary
Concomitant
Pulmonary Hypertension Death 9/23/2009 Female 10/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 74 Female 164 lb 10/20/2009 United States
Primary
Concomitant
Weight Increased Other Serious 30 Male 10/22/2009 Lawyer United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 76 Male 15 lb 10/22/2009 United States
Primary
Concomitant
Vomiting Death 1/22/2008 57 Male 10/22/2009 United States
Primary
Concomitant
Ventricular Failure Other Serious 30 Male 226 lb 10/26/2009 United States
Primary
Concomitant
Vomiting Hospitalization 74 Female 164 lb 10/26/2009 United States
Primary
Concomitant
Panic Attack Other Serious 62 Male 229 lb 10/26/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 74 Female 164 lb 12/2/2009 United States
Primary
Concomitant
Wound Secretion Hospitalization Male 12/1/2009 Lawyer United States
Primary
Concomitant
Hepatic Steatosis Other Serious 77 Female 132 lb 12/24/2009 Other Health Professional France
Primary
Concomitant
Right Ventricular Failure Hospitalization 1/7/2010 Female 131 lb 1/19/2010 Physician United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 55 Male 1/7/2010 United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 1/22/2008 57 Male 1/7/2010 United States
Primary
Concomitant
Wound Hospitalization 1/7/2007 49 Male 1/8/2010 United States
Primary
Concomitant
Vomiting Hospitalization 74 Female 164 lb 1/8/2010 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 65 Male 1/13/2010 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization Female 131 lb 1/22/2010 Physician United States
Primary
Concomitant
Poisoning Death 12/23/2009 Male 238 lb 1/1/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis In Device Hospitalization 1/29/2010 Male 134 lb 3/22/2010 Physician Bulgaria
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 10/8/2009 66 Female 3/31/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/7/2010 United States
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 12/21/2009 52 Female 174 lb 12/31/2009 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 58 Male 292 lb 4/13/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 71 Female 146 lb 4/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 73 Female 4/15/2010 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 9/18/2009 50 Male 4/29/2010 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/28/2010 United States
Primary
Concomitant
Hypothyroidism Other Serious 1/5/2010 73 Female 5/11/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/1/2010 69 Female 146 lb 5/17/2010 Physician Australia
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 5/11/2010 United States
Primary
Concomitant
Renal Impairment Other Serious 3/1/2010 69 Female 146 lb 5/21/2010 Physician Australia
Primary
Concomitant
Ventricular Tachycardia Other Serious 76 Male 5/18/2010 United States
Primary
Concomitant
Weight Increased Other Serious 30 Male 226 lb 6/1/2010 United States
Primary
Concomitant
Wheezing Hospitalization 81 Male 6/2/2010 United States
Primary
Concomitant
Vomiting Other Serious 28 Male 6/11/2010 Lawyer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 6/4/2010 63 Female 131 lb 6/22/2010 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms Female 6/29/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 7/29/2009 Female 6/29/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 6/21/2010 63 Female 145 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Flatulence 3/30/2009 88 Female 135 lb 7/29/2010 Consumer United States
Primary
Concomitant
Completed Suicide Death 6/9/2003 59 Male 8/12/2010 Physician United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 41 Male 8/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 41 Male 8/17/2010 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 41 Male 8/17/2010 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 12/1/2009 80 Male 8/19/2010 Other Health Professional France
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 6/4/2010 57 Male 290 lb 8/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/14/2010 63 Male 8/25/2010 Consumer
Primary
Concomitant
Weight Decreased Other Serious 49 Male 8/10/2010 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 41 Male 8/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Flushing 8/24/2009 66 Female 230 lb 8/27/2010 United States
Primary
Concomitant
Upper Respiratory Tract Infection 12/17/2009 66 Female 230 lb 8/28/2010 United States
Primary
Concomitant
Flushing 1/1/2009 77 Male 156 lb 8/28/2010 Consumer
Primary
Concomitant
Headache 5/13/2010 75 Male 220 lb 8/29/2010 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 6/4/2010 63 Female 131 lb 8/27/2010 Physician United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 41 Male 8/31/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 41 Male 8/31/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 41 Male 9/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tinnitus Other Serious 41 Male 9/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/14/2010 63 Male 9/3/2010 Consumer
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 65 Female 9/2/2010 United States
Primary
Concomitant
Weight Increased Other Serious 34 Female 9/16/2010 United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 9/30/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 12 Female 66 lb 10/28/2010 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 64 10/27/2010 Other Health Professional Brazil
Primary
Concomitant
Tinnitus Other Serious 67 Female 10/21/2010 United States
Primary
Concomitant

Drug Data