Amiodarone combined with Digoxin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 9/14/2005 57 Female 211 lb 1/12/2006 United States
Primary
Concomitant
Somnolence Required Intervention 12/18/2005 78 Male 166 lb 12/21/2005 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 9/30/2005 83 Female 62 lb 1/20/2006 Physician United States
Primary
Secondary
Concomitant
Hyperaldosteronism Hospitalization 12/28/2004 73 Female 121 lb 2/3/2006 Consumer France
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 11/1/2005 75 Male 152 lb 2/10/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Other Serious 1/4/2006 78 Female 2/15/2006 United Kingdom
Primary
Concomitant
Contusion Other Serious 12/19/2005 90 Female 130 lb 1/20/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 64 Male 2/28/2006 Israel
Primary
Concomitant
Subdural Haematoma Other Serious 1/27/2004 66 Female 2/27/2006 France
Primary
Secondary
Concomitant
Sudden Death Death 11/8/2004 78 Male 112 lb 3/9/2006 Consumer United Kingdom
Primary
Concomitant
Urine Colour Abnormal Hospitalization 1/28/2005 45 Male 3/27/2006 Physician Philippines
Primary
Concomitant
Ventricular Tachycardia Hospitalization 11/1/2005 75 Male 152 lb 4/11/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Other Serious 3/3/2006 63 Female 155 lb 4/12/2006 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/4/2005 Male 2/21/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 4/27/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/1/2006
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 4/1/2003 70 Female 170 lb 5/12/2006 Physician United States
Primary
Concomitant
Melaena Hospitalization 1/25/2006 84 Male 174 lb 5/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 114 lb 5/18/2006 United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 82 Female 5/19/2006
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/29/2006 72 Male 229 lb 5/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 7/29/2005 77 Male 225 lb 6/8/2006 Consumer France
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 6/5/2006 58 Male 174 lb 6/7/2006 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged 4/16/2006 60 Male 300 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
Headache 6/1/2006 76 Female 150 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Cardiac Arrest Death 11/13/2006 57 Female 201 lb 11/30/2006 Other Health Professional United States
Primary
Concomitant
Shock Other Serious 68 172 lb 3/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Thrombocythaemia Other Serious 10/30/2006 88 Female 110 lb 6/11/2007 Other Health Professional Portugal
Primary
Concomitant
Paraesthesia Other Serious 68 172 lb 6/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Proteinuria Disability 1/1/2007 58 Male 249 lb 6/29/2007 Consumer Brazil
Primary
Secondary
Concomitant
Shock Other Serious 68 172 lb 6/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Overdose Hospitalization 10/28/2006 84 Male 119 lb 7/2/2007 Physician France
Primary
Concomitant
Ventricular Fibrillation Life Threatening 5/31/2004 Male 143 lb 7/9/2007 Physician Italy
Primary
Secondary
Concomitant
Orthopnoea Hospitalization 1/1/2007 62 Male 159 lb 8/31/2007 Physician Switzerland
Primary
Concomitant
Renal Failure Acute Hospitalization 7/1/2007 79 Male 9/7/2007 Other Health Professional France
Primary
Secondary
Thrombocytopenia Other Serious 8/6/2007 Male 184 lb 10/5/2007 Pharmacist United States
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 1/1/2007 58 Male 10/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 1/1/2007 Male 281 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Femur Fracture Hospitalization 8/7/2007 79 Female 106 lb 10/9/2007 Physician France
Primary
Concomitant
Femur Fracture Hospitalization 8/7/2007 79 Female 106 lb 10/9/2007 Physician France
Primary
Concomitant
Pulmonary Oedema Hospitalization 10/6/2007 61 Male 150 lb 10/15/2007 Physician United Kingdom
Primary
Concomitant
Hair Growth Abnormal 1/1/2003 71 Female 10/25/2007 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 68 Male 10/26/2007 Other Health Professional France
Primary
Secondary
Urinary Tract Infection Other Serious 9/24/2007 53 Female 10/27/2007 Physician Guatemala
Primary
Concomitant
Alopecia 81 Female 11/14/2007 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2007 60 Male 11/14/2007 Consumer United States
Primary
Concomitant
Overdose Death 1/1/2006 82 Male 1/17/2008 Other Health Professional United States
Primary
Secondary
Troponin I Increased Other Serious 9/28/2007 78 Male 1/16/2008 Pharmacist United States
Primary
Secondary
Cerebrovascular Accident Life Threatening 12/8/2007 82 Male 128 lb 1/24/2008 Consumer Brazil
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2002 Male 217 lb 1/28/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/11/2007 94 Female 99 lb 2/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 4/1/2007 71 Male 5/8/2008 Consumer United States
Primary
Concomitant
Sarcoma Other Serious 1/1/2007 Female 95 lb 5/22/2008 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious Male 5/23/2008 Other Health Professional France
Primary
Concomitant
Interacting
Sarcoma Other Serious 1/1/2007 Female 95 lb 5/19/2008 Physician United States
Primary
Concomitant
Syncope Other Serious 80 Male 5/28/2008 Physician United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious 77 Female 152 lb 7/15/2008 United States
Primary
Concomitant
Postoperative Wound Infection Life Threatening 6/19/2008 78 Male 134 lb 7/29/2008 United States
Primary
Secondary
Concomitant
Cardioactive Drug Level Above Therapeutic Hospitalization 6/19/2008 78 Male 8/4/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/17/2008 62 Female 164 lb 7/21/2008 United States
Primary
Concomitant
Laboratory Test Interference Life Threatening 3/22/2008 81 Male 125 lb 6/29/2008 Pharmacist United States
Primary
Secondary
Concomitant
Phlebitis Other Serious 5/9/2008 Male 8/26/2008 Other Health Professional Australia
Primary
Concomitant
Flushing 1/1/2005 Male 200 lb 8/27/2008 Consumer United States
Primary
Concomitant
Flushing 1/1/2007 Male 8/27/2008 Consumer United States
Primary
Secondary
Concomitant
Flushing 6/15/2008 Male 8/29/2008 United States
Primary
Concomitant
Dyspnoea Hospitalization 7/19/2008 56 Male 9/2/2008 Other Health Professional United States
Primary
Concomitant
Pubic Rami Fracture Hospitalization 1/28/2005 Female 9/4/2008 Other Health Professional Australia
Primary
Concomitant
Multi-organ Failure Death 4/16/2008 77 Male 166 lb 9/19/2008 United States
Primary
Concomitant
Shock Other Serious 68 172 lb 9/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Skin Tightness Other Serious 12/1/2006 79 Male 187 lb 9/27/2008 Physician United States
Primary
Concomitant
Renal Failure Other Serious 77 Female 152 lb 9/22/2008 Consumer United States
Primary
Concomitant
Wound Hospitalization 3/1/2008 69 Male 330 lb 9/26/2008 United States
Primary
Concomitant
Weight Increased Hospitalization 73 Female 166 lb 9/29/2008 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 86 Female 10/8/2008
Primary
Secondary
Concomitant
Shock Other Serious 68 172 lb 10/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Arrhythmia Hospitalization 45 Male 199 lb 1/21/2009 Lawyer United States
Primary
Concomitant
Left Ventricular Dysfunction Hospitalization 45 Male 199 lb 1/24/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/1/2006 Male 150 lb 2/2/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/1/2006 Male 150 lb 2/6/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/21/2009 Male 174 lb 2/11/2009 Physician Argentina
Primary
Secondary
Concomitant
Ventricular Arrhythmia Hospitalization 45 Male 199 lb 2/4/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization Female 102 lb 2/11/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 81 Male 2/25/2009
Primary
Secondary
Vomiting Hospitalization Female 3/20/2009 Consumer United States
Primary
Secondary
Concomitant
Scar Other Serious Male 209 lb 4/6/2009 Lawyer United States
Primary
Secondary
Concomitant
Xanthopsia Hospitalization 73 Female 166 lb 4/7/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 4/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Intraventricular Haemorrhage Death 2/22/2009 58 Male 187 lb 4/29/2009 Physician Spain
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 4/29/2009
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 5/1/2009 Consumer United Kingdom
Primary
Secondary
Ventricular Tachycardia Required Intervention 68 Male 4/27/2009
Primary
Secondary
Sepsis Hospitalization 12/19/2005 Male 295 lb 5/6/2009 Physician United States
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 70 Female 5/7/2009 Other Health Professional Greece
Primary
Concomitant
Sudden Death Death 5/8/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 5/8/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 5/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 172 lb 5/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Unevaluable Event Death 64 Male 179 lb 5/7/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 5/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 172 lb 5/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Oedema Peripheral Other Serious 5/12/2009 Female 160 lb 5/21/2009 Canada
Primary
Concomitant
Oedema Peripheral Other Serious 5/12/2009 Female 160 lb 5/22/2009 Canada
Primary
Concomitant
Pneumonia Other Serious 2/14/2006 Male 150 lb 5/27/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Therapeutic Agent Toxicity Other Serious 78 Female 6/5/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 64 Male 179 lb 6/5/2009 Lawyer United States
Primary
Concomitant
Cardiac Fibrillation Other Serious 10/1/2008 Male 215 lb 6/16/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 73 Female 152 lb 6/10/2009 United States
Primary
Concomitant
Paraesthesia Oral 6/23/2008 66 Female 143 lb 6/17/2009 United States
Primary
Concomitant
Respiratory Failure Death 4/8/2009 Male 6/17/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 4/13/2009 Female 129 lb 6/19/2009 Consumer United States
Primary
Concomitant
Injury Other Serious Male 6/14/2009 United States
Primary
Concomitant
Vomiting Hospitalization 1/7/2007 49 Male 6/14/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/4/2003 Male 193 lb 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/30/2003 Male 6/25/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 6/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 172 lb 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 5/24/2008 79 Male 189 lb 7/12/2009 United States
Primary
Concomitant
Multiple Injuries Hospitalization 46 Male 7/13/2009 Lawyer United States
Primary
Concomitant
Tremor Hospitalization 72 Female 7/13/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 73 Male 7/20/2009 Pharmacist United States
Primary
Concomitant
Unevaluable Event Death 69 Female 7/15/2009 Lawyer United States
Primary
Concomitant
Wound Hospitalization 71 Male 7/16/2009 Lawyer United States
Primary
Concomitant
Visual Impairment Hospitalization 10/25/2007 73 Male 229 lb 7/15/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 74 Male 7/15/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 7/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Extrasystoles Other Serious 76 Male 165 lb 7/17/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 10/25/2007 73 Female 229 lb 7/17/2009 United States
Primary
Concomitant
Heart Rate Decreased Other Serious 3/25/2009 Male 161 lb 7/23/2009 Consumer United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 68 Male 7/24/2009 Other Health Professional France
Primary
Secondary
Atrial Fibrillation Other Serious 9/29/2008 Male 215 lb 7/24/2009 Physician United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 5/9/2009 Male 161 lb 7/28/2009 Consumer United States
Primary
Secondary
Concomitant
Circulatory Collapse Death 11/11/2008 Male 7/27/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 73 Male 7/28/2009 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Required Intervention 68 Male 7/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 10/1/2008 Male 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2/9/2009 80 Female 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 7/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/13/2009 Female 129 lb 8/17/2009 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 62 Male 8/4/2009 United States
Primary
Concomitant
Unevaluable Event Death 76 Female 8/4/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 55 Male 254 lb 8/9/2009 Lawyer United States
Primary
Concomitant
Injury Other Serious 76 Female 8/11/2009 Lawyer United States
Primary
Concomitant
Tremor Hospitalization 72 Female 118 lb 8/11/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 4/23/2007 54 Female 258 lb 8/12/2009 United States
Primary
Concomitant
Vomiting Hospitalization 46 Male 8/13/2009 United States
Primary
Concomitant
Urinary Incontinence Hospitalization 76 Female 184 lb 8/12/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 64 Male 179 lb 8/13/2009 United States
Primary
Concomitant

Drug Data