Amikacin combined with Vancomycin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 4/19/2005 48 Female 132 lb 2/8/2006
Primary
Secondary
Concomitant
Renal Failure Other Serious 11/28/2005 75 Male 125 lb 2/15/2006 Physician Japan
Primary
Secondary
Concomitant
Retinal Ischaemia Other Serious 51 Male 2/24/2006 Physician India
Primary
Concomitant
Tachypnoea Other Serious 6 Female 31 lb 3/8/2006 Physician France
Primary
Concomitant
Pneumonia Required Intervention 2/7/2006 13 Female 3/14/2006 France
Primary
Concomitant
Thrombocytopenia Death 3/26/2006 73 Male 4/24/2006 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 9 Male 41 lb 5/8/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Type Iv Hypersensitivity Reaction Hospitalization 2/10/2005 12 Female 73 lb 5/17/2006 Physician France
Primary
Secondary
Sudden Death Other Serious Male 250 lb 6/2/2006 Physician United States
Primary
Concomitant
Interacting
Erythema Multiforme Hospitalization 5/27/2006 34 Female 203 lb 6/4/2006 Pharmacist United States
Primary
Concomitant
Respiratory Depression Other Serious Male 250 lb 6/13/2006 Physician United States
Primary
Concomitant
Interacting
Respiratory Disorder Other Serious 10/19/2005 0 Female 6/16/2006 Physician Spain
Primary
Concomitant
Patent Ductus Arteriosus Other Serious 6/16/2006 0 Male 6/27/2006 Belgium
Primary
Concomitant
Vomiting Required Intervention 6/9/2006 48 Female 227 lb 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Death 1/1/2005 71 Female 7/19/2006 Physician United States
Primary
Concomitant
Pleural Effusion Required Intervention 2/7/2006 13 Female 7/19/2006 Physician France
Primary
Concomitant
Urinary Tract Infection Enterococcal Other Serious 1/1/2005 23 Male 7/19/2006 Physician United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 77 Female 7/19/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious Male 250 lb 7/28/2006 Physician United States
Primary
Concomitant
Interacting
Thrombocytopenia Neonatal Life Threatening 1/3/2006 0 Male 7/24/2006 Belgium
Primary
Concomitant
Respiratory Arrest Other Serious Male 250 lb 8/23/2006 Physician United States
Primary
Concomitant
Interacting
Sudden Death Other Serious Male 250 lb 8/25/2006 Physician United States
Primary
Concomitant
Interacting
Sudden Death Other Serious Male 250 lb 9/8/2006 Physician United States
Primary
Concomitant
Interacting
Respiratory Distress Death 7/20/2006 21 Female 132 lb 9/8/2006 Other Health Professional Belgium
Primary
Concomitant
Respiratory Distress Death 7/20/2006 21 Female 132 lb 9/12/2006 Other Health Professional Belgium
Primary
Concomitant
Respiratory Arrest Other Serious Male 250 lb 9/14/2006 Physician United States
Primary
Concomitant
Interacting
Myocardial Infarction Death 7/20/2006 21 Female 132 lb 9/15/2006 Other Health Professional Belgium
Primary
Concomitant
Sepsis Neonatal Other Serious 9/10/2006 10 Male 9/22/2006 Belgium
Primary
Concomitant
Respiratory Arrest Other Serious Male 250 lb 10/10/2006 Physician United States
Primary
Concomitant
Interacting
Therapy Non-responder Other Serious 9/10/2006 0 Male 10/9/2006 Physician Belgium
Primary
Concomitant
Drug Ineffective Hospitalization 7/1/2005 56 Male 8/8/2006 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Other Serious Male 250 lb 11/2/2006 Physician United States
Primary
Concomitant
Interacting
Respiratory Arrest Other Serious Male 250 lb 11/6/2006 Physician United States
Primary
Concomitant
Interacting
Vomiting Other Serious 3 Male 11/6/2006
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/13/2005 62 Female 190 lb 8/11/2006 Pharmacist United States
Primary
Concomitant
Sepsis Neonatal Other Serious 9/10/2006 0 Male 11/13/2006 Other Health Professional Belgium
Primary
Concomitant
Retinal Degeneration Other Serious 12/12/2006 Other Health Professional Switzerland
Primary
Concomitant
Sepsis Neonatal Other Serious 9/10/2006 0 Male 12/7/2006 Belgium
Primary
Concomitant
Urticaria Hospitalization 9/1/2006 8 Male 12/19/2006 Consumer France
Primary
Secondary
Urticaria Papular Hospitalization 9/1/2006 8 Male 12/22/2006 Other Health Professional France
Primary
Secondary
Concomitant
Patent Ductus Arteriosus Other Serious 10/31/2005 0 Female 12/21/2006 Spain
Primary
Concomitant
Rhabdomyolysis Life Threatening 11/28/2006 0 Female 5 lb 12/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Serum Sickness Other Serious 9/1/2006 8 Male 12/22/2006 France
Primary
Secondary
Vomiting Other Serious 3 Male 1/9/2007 Consumer Australia
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 9/1/2006 8 Male 1/17/2007 Other Health Professional France
Primary
Secondary
Renal Failure Acute Hospitalization 12/29/2006 30 Female 1/19/2007 Physician Italy
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 11/28/2006 Female 5 lb 1/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Urticaria Papular Hospitalization 9/1/2006 8 Male 1/22/2007 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/29/2006 30 Female 1/31/2007 Physician Italy
Primary
Secondary
Concomitant
Urticaria Papular Hospitalization 9/1/2006 8 Male 3/8/2007 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/29/2006 30 Female 3/26/2007 Physician Italy
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Life Threatening 1 3/29/2007 Turkey
Primary
Secondary
Thrombocytopenia Other Serious 0 Male 3/30/2007 Physician Belgium
Primary
Concomitant
Urticaria Papular Hospitalization 9/1/2006 8 Male 4/16/2007 Physician France
Primary
Secondary
Concomitant
Somnolence Other Serious 1/27/2007 87 Male 143 lb 1/31/2007 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 9/29/2006 79 Male 160 lb 5/4/2007 Japan
Primary
Concomitant
Visual Disturbance Other Serious 1/20/2007 21 Male 150 lb 5/8/2007 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Other Serious Male 250 lb 5/10/2007 Physician United States
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 5/11/2007 9 Female 56 lb 7/16/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Bacterial Death 9/29/2006 79 Male 160 lb 7/30/2007 Japan
Primary
Concomitant
Glycogen Storage Disease Type Ii Death 5/26/2007 1 Male 7/30/2007 Physician Israel
Primary
Concomitant
Weight Decreased Hospitalization 5/11/2007 9 Female 56 lb 7/27/2007 United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 12/6/2004 Male 168 lb 8/14/2007 Physician Italy
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 5/1/2007 17 Male 9/10/2007 United States
Primary
Secondary
Vomiting Other Serious 8 Male 10/2/2007
Primary
Secondary
Concomitant
Heart Rate Decreased Other Serious 2/6/2006 76 Male 112 lb 10/9/2007 Other Health Professional Japan
Primary
Concomitant
Heart Rate Decreased Other Serious 2/6/2006 76 Male 112 lb 10/10/2007 Other Health Professional Japan
Primary
Concomitant
Heart Rate Decreased Other Serious 2/6/2006 76 Male 112 lb 10/11/2007 Other Health Professional Japan
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 2/6/2006 76 Male 112 lb 10/15/2007 Other Health Professional Japan
Primary
Concomitant
Sepsis Life Threatening 12/24/2006 Male 174 lb 10/17/2007 Consumer United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/6/2006 76 Male 112 lb 10/25/2007 Other Health Professional Japan
Primary
Concomitant
Sepsis Life Threatening 12/24/2006 Male 174 lb 10/25/2007 Consumer United States
Primary
Secondary
Concomitant
Neutropenic Infection Other Serious 9/25/2007 46 Male 10/4/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/11/2007 9 Female 56 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Pulmonary Artery Thrombosis Death 9/15/1992 38 Male 128 lb 11/9/2007 Physician France
Primary
Concomitant
Renal Failure Acute Other Serious 4/1/2007 51 Male 11/13/2007 Other Health Professional France
Primary
Secondary
Concomitant
Septic Shock Hospitalization 5/20/2007 Female 11/13/2007 Other Health Professional France
Primary
Secondary
Concomitant
Restlessness 10/29/2007 64 Male 220 lb 11/13/2007 Physician United States
Primary
Concomitant
Pulmonary Artery Thrombosis Death 9/15/1992 38 Male 128 lb 11/23/2007 Physician France
Primary
Concomitant
Renal Failure Acute Other Serious 4/1/2007 51 Male 11/26/2007 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/29/2007 64 Male 220 lb 11/19/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/14/2007 43 Female 249 lb 11/19/2007 Other Health Professional Italy
Primary
Concomitant
Renal Failure Acute Other Serious 4/1/2007 51 Male 11/27/2007 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/2/2007 15 Female 208 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 4/1/2007 51 Male 11/30/2007 Physician France
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 11/5/2007 15 Female 208 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Serratia Infection Life Threatening 10/14/2007 43 Female 249 lb 12/5/2007 Other Health Professional Italy
Primary
Concomitant
Ventricular Fibrillation Other Serious 10/14/2007 43 Female 249 lb 12/7/2007 Other Health Professional Italy
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/29/2007 64 Male 220 lb 12/7/2007 United States
Primary
Concomitant
Respiratory Rate Increased Hospitalization 12/4/2007 66 Female 210 lb 12/12/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/11/2007 9 Female 56 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/11/2007 0 Female 12/21/2007 Consumer France
Primary
Secondary
Concomitant
Nephritis Interstitial Other Serious 1/1/2007 60 Male 12/26/2007
Primary
Concomitant
Viral Infection Death 11/30/2007 51 Female 106 lb 12/28/2007 Physician Belgium
Primary
Concomitant
Ventricular Dysfunction Life Threatening 11/3/2007 16 Female 208 lb 12/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 57 lb 12/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Disorder Required Intervention 7 Male 1/10/2008 Physician Turkey
Primary
Concomitant
Visceral Congestion Other Serious 3/4/2004 Male 250 lb 1/23/2008 Lawyer United States
Primary
Concomitant
Interacting
Drug Toxicity Other Serious 3/4/2004 Male 250 lb 1/23/2008 Lawyer United States
Primary
Concomitant
Sepsis Death 1/1/2007 51 Male 132 lb 1/24/2008 India
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 17 Male 1/18/2008 France
Primary
Secondary
Concomitant
Liver Disorder Death 45 Male 1/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/11/2007 9 Female 56 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Death 45 Male 2/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Staphylococcal Hospitalization 12/4/2007 66 Female 210 lb 2/1/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 48 Female 2/6/2008 Saudi Arabia
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 48 Female 2/5/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 1/8/2007 57 Male 204 lb 9/7/2007 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Death 77 Female 2/13/2008 Bulgaria
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 11/29/2007 Female 90 lb 3/7/2008 Other Health Professional France
Primary
Concomitant
Interacting
Necrotising Enterocolitis Neonatal Required Intervention 1/22/2008 0 Male 2 lb 2/29/2008 Physician Belgium
Primary
Concomitant
Urinary Tract Obstruction Required Intervention 3/9/2008 46 Male 298 lb 3/25/2008 Pharmacist United States
Primary
Secondary
White Blood Cell Count Decreased 11/29/2007 Female 90 lb 3/31/2008 Other Health Professional France
Primary
Concomitant
Interacting
Vomiting Hospitalization 12/4/2007 66 Female 200 lb 3/25/2008 Physician United States
Primary
Concomitant
Transaminases Increased Hospitalization 12/30/2007 5 Male 42 lb 4/3/2008 Physician Belgium
Primary
Concomitant
Transaminases Increased Hospitalization 12/30/2007 5 Male 42 lb 4/7/2008 Physician Belgium
Primary
Concomitant
Venoocclusive Disease Life Threatening 11/3/2007 16 Female 208 lb 4/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Atrioventricular Block Life Threatening 12/5/2007 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Sinusitis Hospitalization 4/23/2007 9 Female 54 lb 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Shock Syndrome Streptococcal Life Threatening 2/1/2008 48 Female 117 lb 4/7/2008 Physician France
Primary
Concomitant
Renal Failure Life Threatening 1/21/2008 24 Female 4/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Endophthalmitis Other Serious 5/5/2008 Physician Thailand
Primary
Secondary
Concomitant
Cardiac Failure Death 3/8/2008 14 Female 5/6/2008 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Other Serious 13 Female 5/16/2008 Physician Belgium
Primary
Concomitant
Pneumonia Other Serious 13 Female 5/19/2008 Physician Belgium
Primary
Concomitant
Liver Disorder Death Male 126 lb 5/19/2008 Consumer United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 5/8/2008 32 Male 5/21/2008 Other Health Professional Italy
Primary
Concomitant
Post Procedural Haemorrhage Death Male 5/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Disorder Death Male 126 lb 5/30/2008 Consumer United States
Primary
Secondary
Concomitant
Liver Disorder Death Male 126 lb 6/3/2008 Consumer United States
Primary
Secondary
Concomitant
Virus Urine Test Positive Hospitalization 17 Male 6/5/2008
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Death Male 6/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 5/8/2008 32 Male 7/11/2008 Other Health Professional Italy
Primary
Concomitant
Septic Shock Death 12 Female 148 lb 7/30/2008 Pharmacist Spain
Primary
Concomitant
Interacting
Respiratory Failure Other Serious 48 Female 7/28/2008 Brazil
Primary
Secondary
Concomitant
Drug Interaction Death 12 Female 126 lb 8/6/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Pneumonia Other Serious 13 Female 8/18/2008 Physician Belgium
Primary
Concomitant
Leukaemia Death 75 Female 8/18/2008 Other Health Professional Sweden
Primary
Concomitant
Vomiting Other Serious 7/16/2007 13 Female 93 lb 9/26/2008 Physician Belgium
Primary
Concomitant
Vomiting Other Serious 7/16/2007 13 Female 93 lb 10/2/2008 Physician Belgium
Primary
Concomitant
Vomiting Other Serious 7/16/2007 13 Female 93 lb 10/9/2008 Physician Belgium
Primary
Concomitant
Respiratory Failure Required Intervention 1/1/1993 48 Female 11/4/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/4/2007 66 Female 200 lb 11/7/2008 Physician United States
Primary
Concomitant
Insomnia Required Intervention 8/23/2008 42 Male 370 lb 11/24/2008 Physician United Kingdom
Primary
Concomitant
Insomnia Required Intervention 8/23/2008 42 Male 370 lb 12/2/2008 Physician United Kingdom
Primary
Concomitant
Premature Baby Hospitalization 2/26/2008 Female 1/21/2009 Other Health Professional France
Primary
Secondary

Drug Data