Ambrisentan combined with Furosemide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Right Ventricular Failure Hospitalization 5/31/2007 Male 189 lb 7/12/2007 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 6/5/2007 Female 151 lb 7/19/2007 United States
Primary
Concomitant
Right Ventricular Failure Other Serious 7/17/2007 Female 269 lb 7/30/2007 United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 11/20/2007 Male 123 lb 12/5/2007 Brazil
Primary
Concomitant
Pulmonary Hypertension Hospitalization 11/20/2007 Male 123 lb 12/17/2007 Brazil
Primary
Concomitant
Death Death 12/25/2007 Female 137 lb 1/7/2008 United States
Primary
Concomitant
Death Death 12/25/2007 Female 137 lb 1/9/2008 United States
Primary
Concomitant
Death Death 12/31/2007 Female 119 lb 1/15/2008 United States
Primary
Concomitant
Death Death 12/25/2007 Female 137 lb 1/17/2008 United States
Primary
Concomitant
Shock Haemorrhagic Life Threatening 1/15/2008 Female 247 lb 1/21/2008 United States
Primary
Concomitant
Shock Haemorrhagic Life Threatening 1/15/2008 Female 247 lb 1/25/2008 United States
Primary
Concomitant
Headache Hospitalization 1/12/2008 Female 280 lb 2/1/2008 United States
Primary
Concomitant
Lower Limb Fracture Hospitalization 1/28/2008 Female 2/7/2008 Canada
Primary
Concomitant
Lower Limb Fracture Hospitalization 1/28/2008 Female 2/8/2008 Canada
Primary
Concomitant
Pleural Effusion Hospitalization 2/4/2008 Male 2/18/2008 United States
Primary
Concomitant
Lower Limb Fracture Hospitalization 1/28/2008 Female 2/19/2008 Canada
Primary
Concomitant
Lower Limb Fracture Hospitalization 1/28/2008 Female 2/29/2008 Canada
Primary
Concomitant
Death Hospitalization 12/31/2007 Female 119 lb 2/29/2008 United States
Primary
Concomitant
Death Hospitalization 12/31/2007 Female 119 lb 3/13/2008 United States
Primary
Concomitant
Lower Limb Fracture Hospitalization 1/28/2008 Female 3/14/2008 Canada
Primary
Concomitant
Pleural Effusion Hospitalization 2/4/2008 Male 4/4/2008 United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 1/17/2007 Female 182 lb 4/10/2008 United States
Primary
Concomitant
Accidental Overdose Other Serious 3/31/2008 Female 202 lb 4/17/2008 United States
Primary
Concomitant
Accidental Overdose Other Serious 3/31/2008 Female 202 lb 4/18/2008 United States
Primary
Concomitant
Weight Increased Other Serious 7/17/2007 Female 269 lb 5/2/2008 United States
Primary
Concomitant
Toxicologic Test Abnormal Death 12/25/2007 Female 137 lb 5/15/2008 United States
Primary
Concomitant
Lower Limb Fracture Hospitalization 1/28/2008 Female 5/15/2008 Canada
Primary
Concomitant
Pregnancy 6/9/2008 Female 128 lb 6/13/2008 Brazil
Primary
Concomitant
Vaginal Haemorrhage Life Threatening 1/15/2008 Female 247 lb 6/13/2008 United States
Primary
Concomitant
Rash Hospitalization 5/22/2008 Female 181 lb 6/17/2008 United Kingdom
Primary
Concomitant
Abortion Induced 6/11/2008 Female 128 lb 6/18/2008 Brazil
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 4/29/2008 Female 159 lb 6/30/2008 Russian Federation
Primary
Concomitant
Rash Hospitalization 5/22/2008 Female 181 lb 7/3/2008 United Kingdom
Primary
Concomitant
Occult Blood Positive Other Serious 6/26/2008 64 Female 119 lb 7/8/2008 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 5/28/2008 Female 250 lb 7/8/2008 United States
Primary
Concomitant
Vaginal Haemorrhage Life Threatening 1/15/2008 Female 247 lb 7/11/2008 United States
Primary
Concomitant
Abortion Induced Other Serious 6/11/2008 Female 128 lb 7/31/2008 Brazil
Primary
Concomitant
Vasodilatation Hospitalization 5/28/2008 Female 250 lb 9/2/2008 United States
Primary
Concomitant
Occult Blood Positive Other Serious 6/26/2008 64 Female 119 lb 9/15/2008 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 5/28/2008 Female 250 lb 11/12/2008 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 5/28/2008 Female 250 lb 11/24/2008 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 2/2/2009 Male 176 lb 2/12/2009 Israel
Primary
Concomitant
Rash Hospitalization 5/22/2008 Female 181 lb 2/27/2009 United Kingdom
Primary
Concomitant
Right Ventricular Failure Hospitalization 2/2/2009 Male 176 lb 4/2/2009 Israel
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/24/2009 Female 137 lb 4/3/2009 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 5/28/2008 Female 250 lb 4/8/2009 United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/24/2009 Female 137 lb 4/14/2009 United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/24/2009 Female 137 lb 5/13/2009 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 5/28/2008 Female 250 lb 5/20/2009 United States
Primary
Concomitant
Cardiac Arrest Hospitalization 4/28/2009 Female 5/27/2009 Physician United Kingdom
Primary
Concomitant
Hepatitis Hospitalization 8/17/2009 Male 165 lb 9/30/2009 Physician United Kingdom
Primary
Concomitant
Hepatitis Hospitalization 8/17/2009 Male 165 lb 10/8/2009 Physician United Kingdom
Primary
Concomitant
Hepatitis Hospitalization 8/17/2009 Male 163 lb 10/13/2009 Physician United Kingdom
Primary
Concomitant
Hypotension Hospitalization 10/10/2009 Female 123 lb 10/23/2009 Brazil
Primary
Concomitant
Pulmonary Hypertension Death 9/23/2009 Female 10/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 7/1/2009 Male 10/27/2009 Physician United Kingdom
Primary
Concomitant
Hypotension Hospitalization 10/10/2009 Female 123 lb 11/11/2009 Brazil
Primary
Concomitant
Treatment Noncompliance Other Serious 9/1/2009 Female 12/2/2009 Physician Canada
Primary
Concomitant
Pulmonary Hypertension Death 9/23/2009 Female 12/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hepatitis Hospitalization 8/17/2009 Male 163 lb 12/16/2009 Physician United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 7/1/2009 Male 12/18/2009 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Death Male 12/30/2009 Physician United Kingdom
Primary
Concomitant
Hepatitis Hospitalization 8/17/2009 Male 163 lb 1/4/2010 Physician United Kingdom
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 10/10/2009 Female 123 lb 3/19/2010 Brazil
Primary
Concomitant
Hepatitis Hospitalization 8/17/2009 Male 163 lb 3/30/2010 Physician United Kingdom
Primary
Concomitant
Pulmonary Oedema Death 67 Male 5/6/2010 Physician Greece
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 10/10/2009 32 Female 123 lb 5/6/2010 Brazil
Primary
Concomitant
Right Ventricular Failure Death 65 Male 5/17/2010 Physician Greece
Primary
Concomitant
Fluid Retention Hospitalization 1/1/2010 64 Female 8/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hepatitis Hospitalization 8/17/2009 44 Male 163 lb 8/20/2010 Physician United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 2/2/2010 63 Male 216 lb 8/26/2010 Physician Netherlands
Primary
Concomitant
Renal Impairment Other Serious 2/2/2010 63 Male 216 lb 11/5/2010 Physician Netherlands
Primary
Concomitant
Hypoxia Hospitalization 12/3/2010 Male 151 lb 12/15/2010 United States
Primary
Concomitant
Hypoxia Hospitalization 12/3/2010 80 Male 151 lb 12/21/2010 United States
Primary
Concomitant
Interstitial Lung Disease Death 3/5/2010 37 Male 12/22/2010 Physician Japan
Primary
Concomitant
Pulmonary Hypertensive Crisis Life Threatening 12/12/2010 44 Female 1/12/2011 Physician Japan
Primary
Concomitant
Hepatitis Hospitalization 8/17/2009 44 Male 163 lb 1/13/2011 Physician United Kingdom
Primary
Concomitant
Hepatitis Hospitalization 8/17/2009 44 Male 163 lb 1/20/2011 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 11/1/2010 37 Female 2/24/2011 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/1/2010 37 Female 3/8/2011 Physician France
Primary
Secondary
Concomitant
Cardiac Failure Death 10/18/2010 38 Male 139 lb 3/29/2011 Physician Japan
Primary
Concomitant
Hypoaesthesia Other Serious Male 4/8/2011 Consumer Canada
Primary
Concomitant
Oedema Peripheral Hospitalization 3/2/2011 63 Male 4/11/2011 Other Health Professional Canada
Primary
Concomitant
Fluid Retention Hospitalization 4/14/2011 63 Male 324 lb 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Oesophageal Carcinoma Death Female 103 lb 5/2/2011 Other Health Professional Australia
Primary
Concomitant
Dyspnoea Hospitalization 12/3/2010 80 Male 151 lb 5/4/2011 Physician United States
Primary
Concomitant
Fluid Retention Hospitalization 4/14/2011 63 Male 324 lb 5/27/2011 Physician United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Hospitalization 5/13/2011 79 Female 6/17/2011 Physician Sweden
Primary
Concomitant
Pulmonary Hypertension Death 80 Female 6/27/2011 Other Health Professional Australia
Primary
Concomitant
Hepatitis C Other Serious 6/13/2011 55 Female 138 lb 6/27/2011 Physician United States
Primary
Secondary
Concomitant
Mixed Liver Injury Hospitalization 5/2/2011 71 Male 8/9/2011 Physician France
Primary
Concomitant
Thermal Burn Other Serious 5/24/2011 47 Female 141 lb 8/29/2011 Other Health Professional Australia
Primary
Concomitant
Hepatitis B Antibody Positive Death 6/13/2011 9/27/2011 Physician United States
Primary
Secondary
Concomitant
Abdominal Hernia Hospitalization 9/20/2011 79 Female 9/28/2011 Other Health Professional Australia
Primary
Concomitant
Hepatitis C Other Serious 6/13/2011 9/29/2011 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 10/6/2011 Consumer Canada
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 12/24/2010 10/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Abdominal Hernia Other Serious 9/17/2011 79 Female 11/3/2011 Other Health Professional Australia
Primary
Concomitant
Liver Function Test Abnormal Other Serious Male 11/10/2011 Consumer Canada
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Death 1/1/2011 56 Female 77 lb 11/25/2011 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 1/1/2011 76 Male 12/1/2011 Consumer Canada
Primary
Concomitant
Foot Fracture Hospitalization Male 12/6/2011 Consumer Canada
Primary
Concomitant
Oedema Peripheral Hospitalization 56 Female 12/9/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 12/24/2010 42 Female 12/9/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2011 76 Male 12/9/2011 Consumer Canada
Primary
Concomitant
Palpitations Hospitalization 11/19/2011 38 Female 1/24/2012 Physician Japan
Primary
Concomitant
General Physical Health Deterioration Hospitalization 11/2/2010 57 Female 114 lb 1/27/2012 Physician United Kingdom
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 12/1/2011 78 Male 2/9/2012 Physician Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Other Serious 2/7/2012 50 Female 2/19/2012 Physician Japan
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Life Threatening 12/1/2011 78 Male 2/23/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Hospitalization 2/21/2012 68 Female 3/1/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatic Encephalopathy Other Serious 2/7/2012 50 Female 3/2/2012 Physician Japan
Primary
Concomitant
Cerebellar Syndrome Disability 1/17/2012 72 Female 3/8/2012 Physician United Kingdom
Primary
Concomitant
Blood Alkaline Phosphatase Increased Hospitalization 2/21/2012 68 Female 3/12/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 3/2/2012 56 Female 3/15/2012 Physician United States
Primary
Secondary
Concomitant
Anaemia Other Serious 1/16/2012 53 Female 3/15/2012 Physician Japan
Primary
Concomitant
Electrolyte Imbalance Other Serious 2/1/2012 56 Female 3/16/2012 Physician United States
Primary
Secondary
Concomitant
Cerebellar Syndrome 1/17/2012 Female 3/21/2012 Physician United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 11/19/2011 38 Female 3/22/2012 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 1/12/2012 48 Female 3/23/2012 Physician Italy
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Death Female 3/23/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 2/9/2011 90 Female 3/29/2012 Physician Japan
Primary
Concomitant
Cerebellar Ataxia Disability 1/17/2012 72 Female 4/5/2012 Physician United Kingdom
Primary
Concomitant
Cerebellar Syndrome Disability 1/17/2012 72 Female 4/11/2012 Physician United Kingdom
Primary
Concomitant
Mental Status Changes Other Serious 2/7/2012 50 Female 4/13/2012 Physician Japan
Primary
Concomitant
Cerebellar Ataxia Disability 1/17/2012 72 Female 4/19/2012 Physician United Kingdom
Primary
Concomitant
Toxic Skin Eruption Hospitalization 4/1/2012 39 Male 4/23/2012 Physician France
Primary
Secondary
Concomitant
Syncope Other Serious 3/2/2012 56 Female 4/24/2012 Physician United States
Primary
Secondary
Concomitant
Hepatitis B Core Antibody Positive Other Serious 6/13/2011 55 Female 5/3/2012 Physician United States
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Life Threatening 12/24/2010 42 Female 5/3/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/12/2011 63 Male 5/7/2012 Physician United States
Primary
Secondary
Concomitant
Foot Fracture Hospitalization Male 5/7/2012 Consumer Canada
Primary
Concomitant
Systemic Sclerosis Hospitalization 4/27/2011 59 Male 5/8/2012 Physician United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 4/25/2012 75 Male 165 lb 5/11/2012 Consumer United States
Primary
Concomitant
Interstitial Lung Disease Life Threatening 5/23/2011 60 Female 5/16/2012 Physician Japan
Primary
Concomitant
Dyspnoea Other Serious 1/1/2011 82 Female 5/23/2012 Pharmacist Canada
Primary
Secondary
Concomitant
Respiratory Failure Death 11/13/2010 80 Male 5/24/2012 Physician Japan
Primary
Concomitant
Palpitations Hospitalization 11/19/2011 38 Female 6/7/2012 Physician Japan
Primary
Concomitant
Renal Impairment Life Threatening 2/9/2011 90 Female 6/12/2012 Physician Japan
Primary
Concomitant
Anaemia Hospitalization 4/18/2012 52 Female 6/13/2012 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 12/4/2011 70 Male 6/14/2012 Consumer Japan
Primary
Concomitant
Respiratory Failure Hospitalization 5/1/2011 60 Female 6/15/2012 Physician Japan
Primary
Concomitant
Respiratory Failure Death 11/13/2010 80 Male 6/18/2012 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 5/1/2011 60 Female 99 lb 6/19/2012 Physician Japan
Primary
Secondary
Concomitant
Increased Upper Airway Secretion Disability 1/1/2011 82 Female 6/29/2012 Pharmacist Canada
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 5/23/2011 60 Female 7/5/2012 Physician Japan
Primary
Secondary
Concomitant
Cardiac Disorder Other Serious 6/1/2012 58 Female 161 lb 7/11/2012 Consumer United States
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 62 Female 7/16/2012 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 62 Female 7/17/2012 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 5/25/2012 55 Female 7/17/2012 Physician United States
Primary
Secondary
Concomitant

Drug Data