Amaryl combined with Nexavar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Chapped Other Serious 1/29/2006 52 Male 2/22/2006 United States
Primary
Concomitant
Rash Other Serious 1/29/2006 52 Male 4/10/2006 United States
Primary
Concomitant
Rash Other Serious 1/29/2006 52 Male 4/10/2006 United States
Primary
Concomitant
Retroperitoneal Haematoma Life Threatening 2/15/2006 86 Female 150 lb 5/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pain 1/1/2006 64 Female 4/24/2006 United States
Primary
Concomitant
Skin Exfoliation Other Serious 1/29/2006 52 Male 6/21/2006 United States
Primary
Concomitant
Stomatitis Other Serious 2/12/2006 73 Female 200 lb 7/18/2006 United States
Primary
Concomitant
Stomatitis 2/12/2006 73 Female 200 lb 7/12/2006 United States
Primary
Concomitant
Pain 1/1/2006 64 Female 10/23/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 66 Female 183 lb 2/27/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Life Threatening 3/6/2007 76 Male 176 lb 3/29/2007 Physician Austria
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 66 Female 183 lb 8/31/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Female 183 lb 8/1/2007 United States
Primary
Concomitant
Weight Decreased Female 183 lb 10/12/2007 United States
Primary
Concomitant
Transaminases Increased Other Serious 9/7/2007 66 Male 11/14/2007 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 9/7/2007 66 Male 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Death Death 12/18/2007 65 Female 181 lb 1/17/2008 Physician United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Disability 5/19/2008 61 Male 190 lb 6/20/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 9/1/2007 74 Male 214 lb 12/23/2008 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/10/2008 69 Male 130 lb 12/23/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 9/1/2007 74 Male 214 lb 12/15/2008 Physician United States
Primary
Concomitant
Angioedema Hospitalization 8/10/2008 68 Male 3/3/2009 Physician Germany
Primary
Secondary
Concomitant
Angioedema Hospitalization 8/10/2008 68 Male 3/10/2009 Other Health Professional
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/23/2008 71 Male 121 lb 4/16/2009 Physician Japan
Primary
Concomitant
Lung Disorder Life Threatening 7/11/2009 80 Female 7/17/2009 Physician Japan
Primary
Concomitant
Acute Respiratory Distress Syndrome Death 7/11/2009 81 Female 7/27/2009 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Other Serious 5/1/2009 83 Male 110 lb 8/5/2009 Physician Japan
Primary
Concomitant
Insomnia Life Threatening 7/10/2009 81 Female 115 lb 8/31/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/29/2009 72 Male 130 lb 9/9/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 8/11/2009 61 Male 161 lb 10/2/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 8/6/2009 67 Male 10/7/2009 Physician Japan
Primary
Concomitant
Malaise Disability 6/4/2009 71 Male 161 lb 10/15/2009 Physician Japan
Primary
Concomitant
Pyrexia 8/6/2009 67 Male 10/29/2009 Physician Japan
Primary
Concomitant
Renal Disorder Hospitalization 9/7/2009 59 Male 143 lb 11/4/2009 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 9/14/2009 67 Male 112 lb 11/9/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/11/2009 61 Male 161 lb 11/12/2009 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 10/1/2009 62 Male 229 lb 11/18/2009 Physician United States
Primary
Concomitant
Liver Disorder Other Serious 10/19/2009 65 Male 128 lb 11/20/2009 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 8/4/2009 68 Female 132 lb 11/20/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/29/2009 72 Male 130 lb 11/23/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 11/23/2009 79 Male 12/1/2009 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 8/24/2009 73 Male 119 lb 12/4/2009 Physician Japan
Primary
Concomitant
Pancytopenia Hospitalization 11/13/2008 65 Female 12/17/2009 Physician Japan
Primary
Concomitant
Hepatic Failure Death 9/30/2009 78 Male 117 lb 12/17/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/1/2009 67 Female 123 lb 12/18/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 6/10/2009 67 Male 119 lb 1/25/2010 Physician Japan
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 7/10/2009 81 Female 115 lb 1/28/2010 Other Health Professional Japan
Primary
Concomitant
Respiratory Failure Life Threatening 9/6/2009 73 Male 123 lb 2/2/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 11/19/2009 79 Male 172 lb 2/2/2010 Physician Japan
Primary
Concomitant
Liver Carcinoma Ruptured Hospitalization 12/10/2009 74 Male 2/4/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/17/2009 62 Male 143 lb 2/8/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 7/29/2009 70 Male 123 lb 2/9/2010 Physician Japan
Primary
Concomitant
Transaminases Increased Other Serious 10/19/2009 65 Male 128 lb 2/12/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/29/2009 72 Male 130 lb 2/23/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 11/5/2009 77 Male 117 lb 3/15/2010 Other Health Professional Japan
Primary
Concomitant
Stomatitis Hospitalization 4/27/2009 70 Male 132 lb 3/18/2010 Physician Japan
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 7/10/2009 81 Female 115 lb 3/23/2010 Other Health Professional Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/17/2009 62 Male 143 lb 3/23/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome 7/23/2008 71 Male 121 lb 4/8/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/24/2010 89 Male 121 lb 4/14/2010 Physician Japan
Primary
Concomitant
Malaise Hospitalization 2/1/2010 78 Male 115 lb 4/15/2010 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 8/4/2009 68 Female 132 lb 4/20/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 7/29/2009 70 Male 123 lb 4/20/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 11/5/2009 77 Male 117 lb 4/23/2010 Other Health Professional Japan
Primary
Concomitant
Lung Disorder Death 7/10/2009 81 Female 115 lb 4/30/2010 Other Health Professional Japan
Primary
Concomitant
Liver Disorder Other Serious 10/19/2009 65 Male 128 lb 5/7/2010 Physician Japan
Primary
Concomitant
Angioedema Hospitalization 8/10/2008 68 Male 5/11/2010 Germany
Primary
Secondary
Concomitant
Malaise 6/4/2009 71 Male 161 lb 5/14/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 7/29/2009 73 Female 77 lb 5/24/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased 7/14/2009 74 Male 163 lb 5/24/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 11/5/2009 77 Male 117 lb 5/27/2010 Other Health Professional Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 8/4/2009 68 Female 132 lb 5/28/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Hospitalization 12/7/2009 65 Male 154 lb 6/3/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/31/2009 67 Female 123 lb 6/9/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 4/17/2010 78 Male 139 lb 7/12/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Failure Death 9/30/2009 78 Male 117 lb 7/20/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Death 9/30/2009 78 Male 117 lb 7/20/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 6/13/2009 67 Male 119 lb 7/27/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Death 9/30/2009 78 Male 117 lb 8/3/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 7/29/2009 70 Male 123 lb 8/9/2010 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 2/24/2010 89 Male 121 lb 8/20/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 6/17/2009 62 Male 143 lb 8/27/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 2/19/2010 74 Male 128 lb 9/3/2010 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 8/24/2009 73 Male 119 lb 9/20/2010 Physician Japan
Primary
Concomitant
Hypothyroidism Hospitalization 7/27/2009 73 Female 77 lb 9/20/2010 Physician Japan
Primary
Concomitant
Intra-abdominal Haemorrhage Death 3/24/2010 64 Male 159 lb 9/22/2010 Physician Japan
Primary
Concomitant
Lung Disorder Death 7/10/2009 81 Female 115 lb 10/11/2010 Physician Japan
Primary
Concomitant
Lung Disorder Death 7/10/2009 81 Female 115 lb 10/27/2010 Physician Japan
Primary
Concomitant
Respiratory Arrest Other Serious 7/29/2009 70 Male 123 lb 11/3/2010 Physician Japan
Primary
Concomitant
Rash Life Threatening 10/1/2010 69 Female 139 lb 11/3/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 9/29/2010 75 Male 157 lb 11/16/2010 Physician Japan
Primary
Concomitant
Decreased Appetite Hospitalization 11/10/2010 70 Female 137 lb 1/28/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 8/3/2009 75 Male 139 lb 1/28/2011 Physician Japan
Primary
Concomitant
Drowning Hospitalization 1/24/2010 64 Male 123 lb 2/28/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 12/3/2009 74 Male 132 lb 3/3/2011 Physician Japan
Primary
Concomitant
Rash Life Threatening 10/1/2010 68 Female 139 lb 3/9/2011 Physician Japan
Primary
Concomitant
Diabetic Ketoacidosis Death 10/27/2010 55 Female 187 lb 3/14/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Death 7/29/2009 69 Male 123 lb 3/15/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Death 7/29/2009 69 Male 123 lb 3/29/2011 Physician Japan
Primary
Concomitant
Liver Carcinoma Ruptured Death 12/10/2009 74 Male 4/1/2011 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 4/21/2009 69 Male 132 lb 4/29/2011 Physician Japan
Primary
Concomitant
Pancytopenia Hospitalization 11/13/2008 65 Female 5/3/2011 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Death 6/17/2009 62 Male 142 lb 5/30/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 5/8/2009 68 Male 102 lb 6/3/2011 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Death 3/6/2011 63 Male 161 lb 6/16/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 3/8/2011 46 Male 161 lb 7/1/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 3/8/2011 46 Male 161 lb 7/8/2011 Physician Japan
Primary
Concomitant
Pneumomediastinum Death 5/7/2011 75 Male 143 lb 7/8/2011 Physician Japan
Primary
Concomitant
Jaundice Hospitalization 2/21/2011 71 Male 143 lb 7/12/2011 Physician Japan
Primary
Concomitant
Cerebral Thrombosis Hospitalization 10/6/2010 66 Female 8/2/2011 Physician Japan
Primary
Concomitant
Cleft Lip Congenital Anomaly 6/24/2010 64 Male 134 lb 8/18/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Death 6/24/2010 64 Male 134 lb 8/23/2011 Physician Japan
Primary
Concomitant
Retinal Vascular Thrombosis Other Serious 6/7/2011 62 Male 148 lb 8/31/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hepatic Encephalopathy Death 7/27/2009 73 Female 77 lb 9/1/2011 Physician Japan
Primary
Concomitant
Blood Uric Acid Increased Death 7/21/2009 79 Male 139 lb 9/20/2011 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Death 6/1/2011 67 Male 159 lb 9/28/2011 Physician Japan
Primary
Concomitant
Oesophageal Varices Haemorrhage Death 2/19/2010 74 Male 128 lb 10/7/2011 Physician Japan
Primary
Concomitant
Malaise Death 7/21/2009 79 Male 139 lb 10/24/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Hospitalization 3/11/2010 81 Male 99 lb 11/10/2011 Physician Japan
Primary
Concomitant
Hypothyroidism Hospitalization 3/11/2010 81 Male 99 lb 11/22/2011 Physician Japan
Primary
Concomitant
Skin Ulcer Hospitalization 10/6/2010 66 Female 12/9/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 6/24/2010 63 Male 134 lb 12/15/2011 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 7/21/2009 79 Male 139 lb 12/21/2011 Physician Japan
Primary
Concomitant
Atrial Thrombosis Hospitalization 8/3/2009 75 Male 139 lb 12/22/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 3/6/2011 63 Male 161 lb 12/26/2011 Physician Japan
Primary
Concomitant
Muscle Spasms Other Serious 8/1/2010 72 Male 135 lb 12/30/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/6/2011 63 Male 161 lb 1/6/2012 Physician Japan
Primary
Concomitant
Muscle Spasms Hospitalization 8/1/2010 72 Male 135 lb 1/10/2012 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 6/28/2011 69 Female 157 lb 1/16/2012 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 6/17/2009 62 Male 142 lb 2/3/2012 Physician Japan
Primary
Concomitant
Diabetes Mellitus Hospitalization 8/1/2010 72 Male 135 lb 2/17/2012 Physician Japan
Primary
Secondary
Concomitant
Insomnia Other Serious 10/18/2011 60 Male 143 lb 2/17/2012 Physician Japan
Primary
Secondary
Concomitant
Hiccups Other Serious 10/18/2011 60 Male 143 lb 2/21/2012 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 7/29/2011 64 Male 137 lb 2/23/2012 Physician Japan
Primary
Concomitant
Cardiac Failure Chronic Other Serious 2/7/2012 78 Male 112 lb 3/13/2012 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 2/19/2010 74 Male 128 lb 3/27/2012 Physician Japan
Primary
Concomitant
Henoch-schonlein Purpura Hospitalization 3/15/2012 72 Male 150 lb 4/10/2012 Physician Japan
Primary
Concomitant
Hyponatraemia Other Serious 8/1/2010 72 Male 135 lb 4/11/2012 Physician Japan
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Other Serious 11/24/2011 59 Male 141 lb 5/1/2012 Physician Japan
Primary
Concomitant
Hyponatraemia Death 6/10/2011 79 Male 143 lb 5/4/2012 Physician Japan
Primary
Concomitant
Hepatic Failure Life Threatening 11/24/2011 59 Male 141 lb 5/7/2012 Physician Japan
Primary
Concomitant
Pain In Extremity Hospitalization 2/1/2011 72 Female 150 lb 5/18/2012 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Other Serious 11/24/2011 59 Male 141 lb 6/26/2012 Physician Japan
Primary
Concomitant
Transaminases Increased Hospitalization 8/1/2010 72 Male 135 lb 7/20/2012 Physician Japan
Primary
Secondary
Concomitant
Rash Life Threatening 6/20/2011 68 Male 123 lb 12/27/2012 Physician Jp
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 6/17/2011 57 Male 132 lb 12/13/2012 Physician Jp
Primary
Secondary
Concomitant
Transaminases Increased Death 8/2010 72 Male 135 lb 7/8/2013 Physician Jp
Primary
Secondary
Concomitant
Pneumonia Chlamydial Death 11/24/2011 59 Male 141 lb 12/20/2012 Physician Jp
Primary
Concomitant
Hypophosphataemia Other Serious 6/10/2011 79 Male 143 lb 4/5/2013 Physician Jp
Primary
Concomitant
Haemoglobin Decreased Other Serious 9/2011 78 Female 97 lb 6/25/2013 Physician Jp
Primary
Concomitant

Drug Data