Amaryl combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Oedema Life Threatening 1/12/2006 62 Male 1/24/2006 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 11/1/2005 49 Male 1/31/2006 Physician Germany
Primary
Concomitant
Stomatitis Hospitalization 10/19/2005 71 Female 2/9/2006 Physician Switzerland
Primary
Secondary
Concomitant
Somnolence Other Serious 1/18/2006 Female 245 lb 2/9/2006 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 1/12/2006 62 Male 2/16/2006 Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 2/16/2006 65 Female 216 lb 3/1/2006 Other Health Professional United States
Primary
Concomitant
Injury Hospitalization 9/11/2003 66 Male 218 lb 3/9/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 9/11/2003 66 Male 218 lb 3/17/2006 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/10/2004 54 Female 220 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2000 45 Male 196 lb 3/31/2006 Lawyer United States
Primary
Concomitant
Polytraumatism Other Serious 1/1/2000 45 Male 196 lb 4/12/2006 Lawyer United States
Primary
Concomitant
Rotator Cuff Syndrome Hospitalization 11/4/2003 54 Female 220 lb 5/2/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/24/2006 66 Male 5/12/2006 Other Health Professional France
Primary
Secondary
Concomitant
Neck Deformity Hospitalization 6/14/2000 52 Female 181 lb 5/17/2006 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased 1/1/2005 68 Female 194 lb 8/1/2006 Consumer United States
Primary
Concomitant
Rash Pruritic 5/1/2006 Female 7/19/2006 United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Hospitalization 8/3/2006 64 Male 11/1/2006 Physician Japan
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 8/3/2006 65 Male 121 lb 11/8/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/12/2006 73 Male 11/7/2006 Japan
Primary
Concomitant
Weight Decreased Hospitalization 12/25/2005 Male 165 lb 11/27/2006 Physician Australia
Primary
Secondary
Concomitant
Vitreous Haemorrhage Hospitalization 8/3/2006 65 Male 128 lb 11/27/2006 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 12/25/2005 Male 165 lb 12/5/2006 Physician Australia
Primary
Secondary
Concomitant
Vitreous Haemorrhage Hospitalization 8/3/2006 65 Male 128 lb 12/8/2006 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 73 Male 1/16/2007 Physician India
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/1/2006 45 Male 1/23/2007 Physician Finland
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 11/1/2006 45 Male 1/31/2007 Physician Finland
Primary
Secondary
Concomitant
Vitreous Haemorrhage Hospitalization 8/3/2006 65 Male 128 lb 2/16/2007 Physician Japan
Primary
Concomitant
Bradycardia Hospitalization 12/21/2006 70 Male 2/5/2007 Japan
Primary
Concomitant
Atrioventricular Block Second Degree Life Threatening 12/21/2006 72 Male 3/1/2007 Japan
Primary
Concomitant
Atrioventricular Block Second Degree Life Threatening 12/21/2006 72 Male 3/9/2007 Japan
Primary
Concomitant
Leukopenia Other Serious 3/22/2007 49 Male 5/4/2007 Japan
Primary
Concomitant
Skin Disorder Other Serious 5/10/2007 61 Male 6/19/2007 Physician Japan
Primary
Concomitant
Blood Glucose Increased Hospitalization 10/1/2006 93 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/1/2006 Female 4/26/2007 United States
Primary
Concomitant
Hyperglycaemia Other Serious 5/23/2006 52 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 5/1/2006 77 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 1/15/2006 61 Male 4/26/2007 United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 11/28/2005 59 Male 185 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Eczema 5/12/2007 61 Male 172 lb 7/5/2007 Physician Japan
Primary
Concomitant
Bone Marrow Failure Other Serious 3/22/2007 49 Male 7/3/2007 Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 10/4/2005 73 Male 7/24/2007 Japan
Primary
Concomitant
Vertebral Artery Stenosis Hospitalization 9/30/2006 80 Male 150 lb 8/9/2007 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 10/4/2005 73 Male 8/30/2007 Japan
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 9/29/2005 58 Male 181 lb 11/5/2007 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 6/25/2007 Male 143 lb 2/28/2008 Japan
Primary
Concomitant
Somnolence Hospitalization 2/29/2008 86 Female 110 lb 3/28/2008 Pharmacist Japan
Primary
Concomitant
Somnolence Hospitalization 2/29/2008 86 Female 110 lb 4/3/2008 Pharmacist Japan
Primary
Concomitant
Renal Cell Carcinoma Stage Iv Other Serious 1/1/2007 48 Male 4/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 6/25/2007 Male 143 lb 5/5/2008 Japan
Primary
Concomitant
Somnolence Hospitalization 2/29/2008 86 Female 110 lb 5/19/2008 Pharmacist Japan
Primary
Concomitant
Vomiting Life Threatening 2/8/2008 68 Male 5/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 3/1/2008 Female 128 lb 6/2/2008 Physician Japan
Primary
Concomitant
Pregnancy Induced Hypertension Hospitalization 8/1/2006 38 Female 6/6/2008 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 3/1/2008 Female 128 lb 6/9/2008 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 5/1/2008 70 Male 5/30/2008 Physician Japan
Primary
Concomitant
Pregnancy Induced Hypertension Hospitalization 8/1/2006 38 Female 6/19/2008 Physician Japan
Primary
Concomitant
Hypoglycaemia Other Serious 64 Male 181 lb 4/30/2008 United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 10/1/2006 93 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 5/1/2006 77 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 4/9/2007 73 Male 138 lb 6/24/2008 Japan
Primary
Concomitant
Vertebral Artery Occlusion Hospitalization 4/9/2007 73 Male 138 lb 7/1/2008 Physician Japan
Primary
Concomitant
Vertebral Artery Occlusion Hospitalization 4/9/2007 73 Male 138 lb 7/25/2008 Japan
Primary
Concomitant
Renal Failure Hospitalization 6/25/2007 Male 143 lb 9/18/2008
Primary
Concomitant
Weight Decreased Other Serious 8/10/2008 Male 182 lb 10/10/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 10/12/2005 71 Male 299 lb 10/20/2008 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 11/1/2003 56 Male 10/20/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 11/11/2008 Female 12/10/2008 Pharmacist United States
Primary
Concomitant
Liver Disorder Hospitalization 11/6/2008 71 Male 12/31/2008 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 11/6/2008 71 Male 1/7/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 79 Male 1/2/2009 Japan
Primary
Concomitant
Liver Disorder Hospitalization 11/6/2008 71 Male 1/15/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 11/25/2008 Male 148 lb 2/20/2009 Physician Japan
Primary
Concomitant
Vasodilatation 12/26/2008 61 Male 2/20/2009 Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 11/25/2008 Male 148 lb 3/18/2009 Physician Japan
Primary
Concomitant
Vertigo Hospitalization 3/17/2009 62 Male 4/6/2009 Japan
Primary
Concomitant
Myocardial Infarction Hospitalization 5/20/2007 58 Male 207 lb 6/2/2009 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 9/1/2006 73 Female 160 lb 6/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 11/1/2000 55 Male 241 lb 6/4/2009 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 1/1/2005 65 Male 200 lb 6/5/2009 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased Other Serious 1/1/2009 75 Male 291 lb 6/15/2009 Consumer United States
Primary
Secondary
Rhabdomyolysis Life Threatening 5/29/2009 68 Female 6/25/2009 Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 2/3/2009 49 7/9/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 7/7/2006 47 Female 229 lb 7/14/2009 United States
Primary
Concomitant
Hepatic Function Abnormal Other Serious 2/3/2009 49 7/29/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 2/3/2009 49 8/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Tricuspid Valve Disease Hospitalization 6/5/2007 44 Male 213 lb 9/25/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 50 Male 354 lb 9/22/2009 United States
Primary
Concomitant
Hypertension Other Serious 4/1/2009 71 Male 10/12/2009 Physician Brazil
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2007 73 Female 180 lb 10/16/2009 Other Health Professional United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 4/22/2009 49 Female 10/19/2009 Consumer United States
Primary
Secondary
Concomitant
Muscle Rupture Hospitalization Male 10/15/2009 Physician Netherlands
Primary
Secondary
Concomitant
Medication Error Male 1/6/2010 United States
Primary
Concomitant
Vomiting Other Serious 12/22/2009 65 Female 1/15/2010 Consumer Turkey
Primary
Concomitant
Cerebral Infarction Other Serious 12/9/2009 74 Male 1/13/2010 Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 10/6/2009 Female 163 lb 2/10/2010 Physician Japan
Primary
Concomitant
Ureteric Obstruction Hospitalization 3/14/2008 66 Male 2/5/2010 United States
Primary
Concomitant
Ureteric Obstruction Hospitalization 3/14/2008 66 Male 2/5/2010 United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 48 Male 170 lb 3/4/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 10/1/2009 59 Female 200 lb 3/8/2010 Consumer United States
Primary
Concomitant
Pulse Absent Hospitalization 2/14/2010 29 Male 250 lb 3/2/2010 Consumer United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 12/1/2007 Male 200 lb 3/17/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 9/1/2008 55 Male 4/6/2010 Japan
Primary
Concomitant
Tachycardia Other Serious 11/1/2007 71 Female 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization Male 194 lb 5/10/2010 Pharmacist United States
Primary
Concomitant
Fall Other Serious 12/1/2008 75 Female 150 lb 5/11/2010 Consumer Brazil
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2009 45 Female 240 lb 5/17/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 62 Male 194 lb 5/19/2010 Pharmacist United States
Primary
Concomitant
Hospitalisation Hospitalization 5/10/2010 66 Male 5/20/2010 Physician United States
Primary
Concomitant
Tremor Other Serious 10/20/2009 66 Male 300 lb 5/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/25/2010 81 Female 5/24/2010 Physician Japan
Primary
Concomitant
Headache 2/1/2010 64 Male 5/27/2010 Physician United States
Primary
Concomitant
Syncope Hospitalization 5/3/2010 59 Female 143 lb 5/27/2010 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 1/1/2010 65 Male 6/4/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 64 Female 6/17/2010 Physician Brazil
Primary
Concomitant
Loss Of Consciousness Other Serious 6/5/2010 Male 6/17/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/1/2009 70 Female 7/8/2010 Japan
Primary
Concomitant
Weight Increased 1/1/2008 49 Female 8/3/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 219 lb 9/10/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious 64 Female 9/13/2010 Physician Brazil
Primary
Concomitant
Nausea 5/26/2009 70 Female 270 lb 10/26/2010 Physician United States
Primary
Concomitant
Tachycardia Other Serious 11/1/2007 71 Female 192 lb 11/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tuberculosis Gastrointestinal Hospitalization 1/25/2010 65 Female 93 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 11/29/2010 70 Male 141 lb 12/14/2010 Pharmacist Switzerland
Primary
Secondary
Concomitant
Rash Other Serious 11/8/2010 30 Female 148 lb 12/15/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Disability 7/30/2009 39 Female 12/17/2010 Japan
Primary
Concomitant
Diabetes Mellitus Hospitalization 11/29/2010 70 Male 141 lb 1/6/2011 Pharmacist Switzerland
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/25/2010 65 Female 93 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 1/25/2010 65 Female 93 lb 1/24/2011 Physician Japan
Primary
Secondary
Concomitant
Bilirubin Conjugated Increased Hospitalization 11/5/2010 Male 2/15/2011 Physician Germany
Primary
Concomitant
Oedema Peripheral Hospitalization 6/7/2007 52 Male 2/7/2011 Japan
Primary
Concomitant
Weight Increased Other Serious 1/1/2010 70 Male 2/17/2011 Consumer Brazil
Primary
Concomitant
Anuria Life Threatening 1/1/2009 65 Female 3/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastric Haemorrhage Other Serious 3/6/2011 82 Male 190 lb 3/18/2011 Consumer Japan
Primary
Concomitant
Gastric Haemorrhage Death 3/6/2011 82 Male 190 lb 3/24/2011 Consumer Japan
Primary
Concomitant
Convulsion Other Serious 8/28/2008 64 Male 3/29/2011 Consumer Denmark
Primary
Concomitant
Pancreatitis Hospitalization 4/3/2011 65 Male 4/29/2011 Consumer Norway
Primary
Concomitant
Diabetes Mellitus Other Serious Female 198 lb 5/4/2011 Consumer Brazil
Primary
Concomitant
Gastrointestinal Perforation Hospitalization 3/1/2011 5/4/2011 Physician Japan
Primary
Concomitant
Vascular Purpura Hospitalization 12/31/2010 56 Male 5/9/2011 Other Health Professional France
Primary
Secondary
Vascular Purpura Hospitalization 12/31/2010 56 Male 5/12/2011 Other Health Professional France
Primary
Secondary
Oedema Peripheral Hospitalization 12/31/2010 56 Male 5/17/2011 France
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 3/10/2010 68 Male 165 lb 5/17/2011 Other Health Professional Japan
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 9/11/2008 59 Male 5/24/2011 Japan
Primary
Concomitant
Bladder Cancer Hospitalization 6/30/2010 66 Male 6/28/2011 Japan
Primary
Concomitant
Bladder Cancer Hospitalization 5/19/2011 70 Male 7/1/2011 Japan
Primary
Concomitant
Anaemia Hospitalization Male 7/14/2011 Other Health Professional France
Primary
Secondary
Concomitant
Nausea Hospitalization 6/1/2011 93 Female 152 lb 7/21/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 65 Female 7/14/2011 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 6/6/2011 93 Female 7/19/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Abdominal Discomfort Life Threatening 68 Male 7/26/2011 Japan
Primary
Concomitant

Drug Data