Amaryl combined with Carvedilol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypoglycaemia Other Serious 2/1/2005 Male 194 lb 1/26/2006 Consumer
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Hospitalization 1/1/2005 Male 2/2/2006 Physician Germany
Primary
Concomitant
Weight Decreased Required Intervention 11/1/2005 76 Female 2/7/2006 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 2/19/2006 84 Male 152 lb 5/24/2006 Switzerland
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/1/2006 44 Male 194 lb 7/10/2006 Physician Japan
Primary
Concomitant
Cardiac Failure Other Serious 1/29/2005 68 Male 7/18/2006 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 6/1/2006 44 Male 194 lb 7/20/2006 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 6/1/2006 44 Male 194 lb 8/2/2006 Physician Japan
Primary
Concomitant
Hypoglycaemia Other Serious 5/27/2006 85 Male 172 lb 7/20/2006 Pharmacist United States
Primary
Concomitant
Cardiac Arrest Death 9/13/2006 53 Female 353 lb 9/21/2006 Physician Germany
Primary
Concomitant
Treatment Noncompliance Hospitalization 7/15/2006 84 Female 9/27/2006 Switzerland
Primary
Secondary
Concomitant
Respiratory Arrest Death 9/13/2006 53 Female 353 lb 10/18/2006 Physician Germany
Primary
Concomitant
Respiratory Arrest Death 9/13/2006 53 Female 353 lb 10/26/2006 Physician Germany
Primary
Concomitant
Oedema Peripheral Death 10/1/2005 75 Male 11/6/2006 Physician Japan
Primary
Concomitant
Hypoglycaemia Other Serious 7/20/2006 80 Male 11/2/2006 Physician Japan
Primary
Concomitant
Oedema Peripheral Death 10/1/2005 75 Male 12/5/2006 Physician Japan
Primary
Concomitant
Oedema Peripheral Death 10/28/2005 75 Male 12/6/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 2/1/2006 65 Female 146 lb 12/12/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/1/2006 65 Female 146 lb 12/12/2006 Consumer United States
Primary
Secondary
Concomitant
Benign Neoplasm Hospitalization 4/14/2005 92 Female 12/18/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 2/1/2006 65 Female 146 lb 12/20/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/1/2006 65 Female 146 lb 1/18/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Death 1/14/2007 70 Female 4/2/2007 Norway
Primary
Concomitant
Muscle Atrophy Other Serious 3/13/2008 Male 234 lb 4/16/2008 Physician Switzerland
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/14/2008 71 Male 5/15/2008 Physician Italy
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 4/19/2008 72 Female 119 lb 6/5/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/25/2008 66 Male 6/20/2008 Consumer Japan
Primary
Secondary
Concomitant
Pruritus Other Serious 11/4/2005 77 Male 216 lb 7/21/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/20/2006 Female 112 lb 8/1/2008 Physician Japan
Primary
Secondary
Concomitant
Sudden Onset Of Sleep Other Serious 7/1/2008 71 Female 8/13/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 5/8/2008 73 Male 132 lb 9/22/2008 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 7/25/2008 72 Male 10/1/2008 Japan
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2008 76 Female 174 lb 10/23/2008 Consumer United States
Primary
Secondary
Concomitant
Pollakiuria Hospitalization 1/1/2008 76 Female 174 lb 11/11/2008 Consumer United States
Primary
Concomitant
Vomiting Disability 44 Male 11/21/2008 Consumer United States
Primary
Secondary
Concomitant
Death Death 10/31/2008 Male 11/24/2008 United States
Primary
Concomitant
Rash Pustular Hospitalization 7/28/2008 68 Male 128 lb 12/22/2008 Physician Japan
Primary
Concomitant
Death Death 10/31/2008 Male 1/21/2009 Physician United States
Primary
Concomitant
Product Quality Issue Death 11/29/2008 92 Male 2/19/2009 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 3/11/2009 76 Female 3/27/2009 Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 3/11/2009 76 Female 4/20/2009 Japan
Primary
Secondary
Concomitant
Renal Failure Death 1/12/2008 69 Female 139 lb 5/15/2009 Physician Japan
Primary
Concomitant
Renal Impairment Life Threatening 4/8/2009 84 Male 132 lb 5/27/2009 Japan
Primary
Secondary
Concomitant
Renal Failure Death 1/12/2008 69 Female 139 lb 6/1/2009 Physician Japan
Primary
Concomitant
Road Traffic Accident Other Serious 2/20/1910 Female 294 lb 6/3/2009 Consumer United States
Primary
Concomitant
Nausea Other Serious 6/15/2009 7/17/2009 Pharmacist Japan
Primary
Concomitant
Hyperkalaemia Life Threatening 4/8/2009 Male 7/17/2009 Japan
Primary
Secondary
Hyperkalaemia Life Threatening 4/8/2009 84 Male 7/21/2009 Japan
Primary
Secondary
Dyspnoea Exertional Hospitalization 7/18/2009 Female 212 lb 7/29/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 60 Male 187 lb 8/13/2009 United States
Primary
Concomitant
Dyspnoea Exertional Hospitalization 7/18/2009 Female 212 lb 8/21/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/2009 Female 128 lb 8/24/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Skin Burning Sensation Male 237 lb 8/23/2009 United States
Primary
Concomitant
Road Traffic Accident Other Serious 2/20/1910 Female 294 lb 8/25/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 7/30/2009 61 10/9/2009 Physician Japan
Primary
Secondary
Concomitant
Surgery Hospitalization 55 Female 10/16/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 51 Female 199 lb 10/26/2009 United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 55 Female 10/26/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 51 Female 199 lb 11/9/2009 United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 55 Female 11/4/2009 United States
Primary
Concomitant
Unemployment Hospitalization 72 Male 11/18/2009 United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 51 Female 199 lb 11/17/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 72 Male 11/20/2009 United States
Primary
Concomitant
Dyspnoea Exertional Hospitalization 7/18/2009 Female 212 lb 12/9/2009 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 Female 12/16/2009
Primary
Secondary
Concomitant
Vomiting 60 Male 12/11/2009 United States
Primary
Concomitant
Dyspnoea Exertional Hospitalization 7/18/2009 Female 212 lb 12/18/2009 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 12/21/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 Female 12/22/2009
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 Female 12/23/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 Female 12/23/2009 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Exertional Hospitalization 7/18/2009 Female 212 lb 1/8/2010 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 Female 89 lb 1/15/2010 Physician Japan
Primary
Secondary
Concomitant
Sleep Disorder Life Threatening 10/1/2009 48 Male 353 lb 1/22/2010 Physician United States
Primary
Concomitant
Visual Impairment Hospitalization 11/19/2008 59 Male 311 lb 3/3/2010 Consumer United States
Primary
Concomitant
Liver Disorder Hospitalization 5/15/2009 67 Female 89 lb 3/29/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphangiosis Carcinomatosa Other Serious 1/4/2010 71 Female 134 lb 4/9/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 58 Male 4/6/2010 Lawyer United States
Primary
Concomitant
Hypoglycaemia Hospitalization 4/19/2010 79 Female 4/29/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphangiosis Carcinomatosa Hospitalization 1/4/2010 71 Female 134 lb 4/30/2010 Physician Japan
Primary
Secondary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 5/15/2009 67 Female 89 lb 5/5/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Warm 4/13/2010 66 Male 5/17/2010 United States
Primary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 5/15/2009 67 Female 89 lb 6/4/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2009 80 Male 223 lb 6/18/2010 Physician United States
Primary
Concomitant
Knee Arthroplasty Hospitalization 1/1/2007 72 Female 185 lb 6/21/2010 Physician United States
Primary
Concomitant
Stent Placement Other Serious 2/18/2010 76 Female 7/8/2010 Consumer Brazil
Primary
Concomitant
Gouty Arthritis Hospitalization 1/27/2009 71 Male 137 lb 8/11/2010 Consumer Korea, Republic Of
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2009 80 Male 223 lb 8/27/2010 Physician United States
Primary
Concomitant
Wheezing Hospitalization 9/7/2010 Male 9/17/2010 Other Health Professional Japan
Primary
Concomitant
Renal Failure Other Serious Male 178 lb 10/1/2010 Consumer United States
Primary
Concomitant
Drug Interaction Other Serious 6/30/2010 56 Male 184 lb 9/28/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/24/2010 67 Male 10/10/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2010 67 Male 231 lb 10/22/2010 Physician Australia
Primary
Secondary
Concomitant
Shock Hospitalization 10/25/2004 57 Female 125 lb 11/10/2010 Lawyer United States
Primary
Concomitant
Pancytopenia Life Threatening 8/18/2010 68 Female 12/10/2010 Physician Japan
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/22/2010 50 Male 136 lb 12/10/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 12/21/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/15/2009 67 Female 12/23/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/24/2010 67 Male 12/30/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 1/1/2010 67 Male 255 lb 1/12/2011 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2010 67 Male 255 lb 1/14/2011 Consumer Australia
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 64 Male 1/27/2011 Physician Hungary
Primary
Concomitant
Myocardial Ischaemia Hospitalization 65 Male 2/1/2011 Physician Hungary
Primary
Concomitant
Cough Hospitalization 6/22/2010 50 Male 136 lb 2/2/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 64 Male 2/11/2011 Physician Hungary
Primary
Concomitant
Myocardial Ischaemia Hospitalization 65 Male 2/11/2011 Physician Hungary
Primary
Concomitant
Anaemia Hospitalization 65 Male 2/14/2011 Physician Hungary
Primary
Concomitant
Overdose Hospitalization 72 Male 4/21/2011 United States
Primary
Concomitant
Abdominal Pain Upper Other Serious 2/18/2010 76 Female 5/6/2011 Consumer Brazil
Primary
Concomitant
Perianal Erythema Hospitalization 3/22/2011 73 Male 176 lb 5/5/2011 Physician United States
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Life Threatening 3/1/2011 57 Male 141 lb 5/31/2011 Physician Japan
Primary
Concomitant
Breast Cancer Hospitalization 7/25/2006 79 Female 137 lb 6/4/2011 Physician Japan
Primary
Concomitant
Atrioventricular Block Hospitalization 4/19/2010 72 Male 123 lb 6/10/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Legionella Hospitalization 5/10/2010 67 Male 161 lb 6/13/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 1/1/2004 69 Male 291 lb 6/16/2011 Lawyer United States
Primary
Concomitant
Blood Creatinine Increased Disability 3/12/2011 68 Male 6/17/2011 Physician Japan
Primary
Concomitant
No Adverse Event Hospitalization 1/12/2011 83 Female 121 lb 6/22/2011 Physician Japan
Primary
Concomitant
Heart Rate Increased Hospitalization 45 Female 199 lb 6/21/2011 United States
Primary
Concomitant
Gouty Arthritis Hospitalization 1/27/2009 71 Male 137 lb 7/5/2011 Consumer Korea, Republic Of
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/13/2011 65 Male 119 lb 7/8/2011 Physician Japan
Primary
Concomitant
Cough Hospitalization 2/14/2010 60 Male 7/11/2011 Other Health Professional Japan
Primary
Concomitant
Dyspnoea Other Serious 5/26/2011 62 Female 7/12/2011 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Concomitant Disease Aggravated Other Serious 2/17/2011 77 Male 126 lb 7/12/2011 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/5/2011 72 Female 229 lb 7/19/2011 Physician Denmark
Primary
Concomitant
Vomiting Death 3/22/2011 73 Male 176 lb 7/18/2011 Physician United States
Primary
Secondary
Concomitant
Skin Hyperpigmentation Hospitalization 3/22/2011 73 Male 176 lb 7/20/2011 Physician United States
Primary
Secondary
Concomitant
Liver Disorder Life Threatening 3/1/2011 57 Male 141 lb 7/27/2011 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 6/7/2010 61 Female 104 lb 8/3/2011 Physician Japan
Primary
Secondary
Concomitant
Pruritus Male 359 lb 8/6/2011 Consumer United States
Primary
Concomitant
Pancreatic Neoplasm Hospitalization 5/18/2010 74 Male 7/29/2011 Spain
Primary
Concomitant
Erysipelas Hospitalization 5/5/2011 72 Female 229 lb 8/12/2011 Physician Denmark
Primary
Concomitant
Cholecystitis Acute Hospitalization 3/22/2011 73 Male 176 lb 8/8/2011 Physician United States
Primary
Concomitant
Dizziness Other Serious 87 Female 8/16/2011 Pharmacist Japan
Primary
Concomitant
Ischaemic Cerebral Infarction Other Serious 5/18/2010 76 Male 8/10/2011 Physician Spain
Primary
Concomitant
Infection Other Serious 6/28/2011 78 Female 99 lb 8/30/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Diastolic Decreased Other Serious 5/25/2010 72 Female 106 lb 8/31/2011 Physician Japan
Primary
Concomitant
Lip Exfoliation Life Threatening 10/1/2009 48 Male 353 lb 9/2/2011 Physician United States
Primary
Concomitant
Cardiac Failure Life Threatening 7/1/2011 78 Male 176 lb 9/6/2011 Other Health Professional Brazil
Primary
Concomitant
Hyperglycaemia Other Serious 5/18/2010 76 Male 8/29/2011 Physician Spain
Primary
Concomitant
Cerebrovascular Accident Hospitalization 7/1/2009 62 Male 250 lb 9/9/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 9/4/2011 59 Male 163 lb 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Other Serious 6/28/2011 78 Female 99 lb 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 9/4/2011 59 Male 163 lb 9/22/2011 Physician Japan
Primary
Secondary
Concomitant
Orthostatic Hypotension Other Serious 3/6/2011 81 Male 159 lb 9/29/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 9/4/2011 59 Male 163 lb 9/30/2011 Physician Japan
Primary
Secondary
Concomitant
Ventricle Rupture Other Serious 7/13/2010 81 Male 139 lb 10/4/2011 Physician Japan
Primary
Concomitant
Blood Potassium Increased Hospitalization 9/14/2010 75 Female 10/10/2011 Physician Japan
Primary
Concomitant
Renal Impairment Disability 3/12/2011 69 Male 170 lb 10/10/2011 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/22/2011 83 Female 117 lb 10/11/2011 Physician Japan
Primary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 85 Male 10/12/2011 Physician Japan
Primary
Concomitant

Drug Data