Alprazolam combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Hospitalization 2/7/2005 68 Male 170 lb 10/31/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 68 Male 170 lb 11/11/2005 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 11/23/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 1/6/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 5/24/2005 71 Female 12/6/2005 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 7/26/2005 Male 2/3/2006 Puerto Rico
Primary
Concomitant
Pleural Effusion Other Serious 7/26/2005 Male 215 lb 2/16/2006 Puerto Rico
Primary
Concomitant
Pulmonary Hypertension Other Serious 9/1/2004 77 Male 165 lb 2/20/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 65 Female 120 lb 2/21/2006 United States
Primary
Secondary
Concomitant
Skin Exfoliation 78 Female 142 lb 12/7/2005 Consumer United States
Primary
Concomitant
Hip Surgery Hospitalization 12/7/2005 51 Female 3/13/2006 Consumer Canada
Primary
Concomitant
Tremor 1/1/2005 64 Female 185 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/26/2005 Male 215 lb 4/7/2006 Puerto Rico
Primary
Concomitant
Urine Output Decreased Other Serious 1/1/2006 75 Male 144 lb 3/30/2006 Consumer United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/1/2006 75 Male 144 lb 4/21/2006 United States
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 12/18/2005 71 Male 3/13/2006 Physician United States
Primary
Concomitant
Tremor 1/1/2005 64 Female 185 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 4/27/2006 71 Female 139 lb 7/14/2006 Physician Portugal
Primary
Concomitant
Erectile Dysfunction 3/1/2006 78 Male 6/28/2006 United States
Primary
Concomitant
Weight Increased Male 7/6/2006 Consumer United States
Primary
Concomitant
Physical Assault Hospitalization 5/7/2006 70 Male 7/25/2006 United States
Primary
Concomitant
Urinary Retention Other Serious 8/3/2006 76 Female 8/8/2006 Physician Japan
Primary
Concomitant
Hypoaesthesia Hospitalization 8/9/2006 69 Male 155 lb 8/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Joint Swelling Other Serious 4/1/2006 45 Female 146 lb 7/19/2006 United States
Primary
Concomitant
Urinary Retention Other Serious 8/3/2006 76 Female 8/16/2006 Physician Japan
Primary
Concomitant
Physical Assault Hospitalization 5/7/2006 70 Male 9/1/2006 United States
Primary
Concomitant
Urinary Retention Other Serious 8/3/2006 76 Female 8/28/2006 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 4/19/2003 69 Female 9/6/2006 Consumer United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 1/13/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/25/2006 Male 203 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Melaena Hospitalization 9/13/2006 56 Male 154 lb 9/21/2006 Pharmacist United States
Primary
Concomitant
Dyspnoea 6/27/2006 76 Female 8/22/2006 United States
Primary
Concomitant
Pharmaceutical Product Complaint 5/1/2006 74 Female 10/30/2006 Consumer United States
Primary
Concomitant
Fall Other Serious 1/1/2006 75 Male 11/10/2006 United States
Primary
Concomitant
Pain In Extremity Other Serious 75 Male 175 lb 11/10/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Other Serious 9/8/2005 85 Male 198 lb 11/20/2006 United States
Primary
Secondary
Concomitant
Headache 9/2/2006 76 Female 202 lb 10/24/2006 United States
Primary
Concomitant
Vocal Cord Inflammation Other Serious 8/1/2005 53 Male 205 lb 11/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 11/24/2006 73 Female 1/30/2007 United States
Primary
Secondary
Concomitant
Dyspnoea 6/27/2006 76 Female 11/21/2006 United States
Primary
Concomitant
Rash 5/29/2006 67 Male 2/28/2007 Consumer United States
Primary
Concomitant
Dry Mouth 8/1/2006 75 Female 12/6/2006 United States
Primary
Concomitant
Fatigue Other Serious 3/23/2007 Male 3/27/2007 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 3/25/2007 58 Male 179 lb 3/29/2007 Pharmacist United States
Primary
Concomitant
Right Ventricular Failure Death 8/18/2006 79 Female 166 lb 1/23/2007 Consumer United States
Primary
Concomitant
Pulmonary Hypertension 3/1/2006 65 Female 152 lb 1/23/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/16/2007 Female 3/28/2007 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/1/2007 54 Female 3/26/2007 Physician Peru
Primary
Secondary
Concomitant
Nausea Other Serious 11/24/2006 73 Female 4/2/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 85 Female 4/25/2007 Sweden
Primary
Concomitant
Visual Disturbance Other Serious 1/1/2007 Male 189 lb 5/14/2007 Consumer United States
Primary
Concomitant
Swelling Face Hospitalization 4/9/2007 49 Female 5/14/2007 Physician Portugal
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 1/26/2007 82 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 5/1/2000 Male 225 lb 6/28/2007
Primary
Concomitant
Overdose 3/9/2007 79 Male 6/29/2007 Consumer United States
Primary
Concomitant
Pregnancy Other Serious 5/29/2007 Female 119 lb 7/3/2007 Argentina
Primary
Concomitant
Vomiting Hospitalization 3/1/2007 54 Female 6/25/2007 Physician Peru
Primary
Secondary
Concomitant
Exercise Tolerance Decreased Hospitalization 7/4/2007 Female 119 lb 7/17/2007 Argentina
Primary
Concomitant
Respiratory Arrest Death 7/31/2007 79 Male 8/11/2007 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 29 Male 8/8/2007 Physician United States
Primary
Concomitant
Suicidal Ideation 1/1/2005 78 Female 185 lb 7/10/2007 Consumer United States
Primary
Concomitant
Multiple Sclerosis Hospitalization 7/5/2007 52 Female 190 lb 8/23/2007 Consumer United States
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 6/1/2004 Male 9/5/2007 United Kingdom
Primary
Secondary
Concomitant
Repetitive Strain Injury Other Serious 1/1/2006 70 Female 9/11/2007 Consumer United States
Primary
Concomitant
Pancytopenia Hospitalization 75 Male 10/5/2007 United States
Primary
Concomitant
Swollen Tongue Hospitalization 9/17/2007 75 Female 10/1/2007 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 2/7/2007 30 Female 187 lb 10/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 5/17/2005 71 Female 150 lb 10/29/2007 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 7/28/2007 74 Male 11/5/2007 Physician United States
Primary
Concomitant
Fall Hospitalization 10/1/2007 Male 11/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Sclerosis Hospitalization 7/5/2007 52 Female 190 lb 11/12/2007 Physician United States
Primary
Concomitant
Syncope Other Serious 1/1/2002 76 Male 141 lb 11/14/2007 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/1/2004 41 Female 147 lb 11/19/2007 Physician United States
Primary
Concomitant
Weight Decreased Death 1/1/2007 75 Male 11/14/2007 Other Health Professional United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 10/17/2007 Male 84 lb 11/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/7/2007 63 Male 165 lb 11/26/2007 Pharmacist United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/17/2007 84 Female 12/4/2007 Pharmacist United States
Primary
Secondary
Concomitant
Panic Attack Other Serious 1/1/2007 2/12/2008 Consumer Portugal
Primary
Secondary
Concomitant
Convulsion Hospitalization 8/1/2007 64 Female 1/17/2008 United States
Primary
Secondary
Concomitant
Myalgia 9/1/2007 71 Male 3/7/2008 Consumer United States
Primary
Concomitant
Blood Pressure Decreased Life Threatening Female 3/12/2008 Pharmacist United States
Primary
Concomitant
Cerebral Haematoma Death 3/18/2008 55 Female 249 lb 3/19/2008 Pharmacist United States
Primary
Concomitant
Syncope Life Threatening 2/20/2008 Female 3/24/2008 Pharmacist United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 7/4/2007 Female 119 lb 4/28/2008 Argentina
Primary
Concomitant
International Normalised Ratio Increased Other Serious 4/1/2008 49 Female 155 lb 5/9/2008 Other Health Professional United States
Primary
Concomitant
Interacting
Macular Degeneration Other Serious Female 6/9/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 78 Male 180 lb 5/7/2008 United States
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Other Serious 61 Female 6/4/2008 Other Health Professional United States
Primary
Concomitant
Vena Cava Injury Death 2/8/2008 Female 180 lb 6/10/2008 Pharmacist United States
Primary
Secondary
Concomitant
Pemphigoid Other Serious Female 6/17/2008 Physician Canada
Primary
Concomitant
Tremor Other Serious 61 Female 6/17/2008 Other Health Professional United States
Primary
Concomitant
Sensation Of Foreign Body Other Serious 1/1/2007 76 Female 6/25/2008 Consumer United States
Primary
Concomitant
Medication Error Hospitalization 1/1/2006 68 Male 7/16/2008 Consumer United States
Primary
Concomitant
Sensory Loss Other Serious 8/1/2007 58 Female 190 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 6/22/2008 73 Female 7/31/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 6/22/2008 Female 8/15/2008 Pharmacist Japan
Primary
Secondary
Flushing 10/15/2007 Female 8/27/2008 Consumer United States
Primary
Concomitant
Swelling 2/26/2008 Female 276 lb 8/27/2008 Physician United States
Primary
Concomitant
International Normalised Ratio Decreased Other Serious Female 8/28/2008
Primary
Secondary
Concomitant
Intestinal Polyp Other Serious 6/21/2008 Female 126 lb 8/29/2008 Physician United States
Primary
Concomitant
Accidental Exposure 8/14/2008 Female 9/13/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious Female 9/16/2008 Pharmacist Japan
Primary
Secondary
Wrong Technique In Drug Usage Process Other Serious Male 210 lb 10/3/2008 Physician United States
Primary
Secondary
Concomitant
Osteopenia Other Serious 5/1/2005 50 Female 210 lb 10/7/2008 United States
Primary
Secondary
Concomitant
Myalgia Other Serious 5/23/2007 60 Male 222 lb 9/19/2008 Physician United States
Primary
Secondary
Concomitant
Nausea Death Male 11/4/2008 United States
Primary
Concomitant
Anaemia Other Serious 6/21/2008 Female 126 lb 11/14/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 11/21/2008 Consumer United States
Primary
Concomitant
Bone Neoplasm Malignant Other Serious Male 11/24/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 11/25/2008 Consumer United States
Primary
Concomitant
Cough 10/24/2008 Female 12/2/2008 Consumer
Primary
Concomitant
Medication Residue 1/1/2005 Male 240 lb 12/4/2008 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 12/11/2008 Consumer United States
Primary
Secondary
Concomitant
Nervousness 85 Female 156 lb 12/17/2008 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 12/18/2008 Consumer United States
Primary
Secondary
Concomitant
Retching Other Serious 11/12/2008 Female 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 1/15/2009 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 12/7/2008 Female 125 lb 2/9/2009 Physician United States
Primary
Concomitant
Productive Cough Other Serious 1/1/2006 78 Female 2/18/2009 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 12/7/2008 Female 125 lb 2/23/2009 Physician United States
Primary
Concomitant
Oropharyngeal Pain 10/24/2008 Female 3/4/2009 Consumer
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 235 lb 3/6/2009 Physician United States
Primary
Concomitant
Toxic Neuropathy Other Serious 58 Male 3/27/2009 Physician United States
Primary
Concomitant
Ventricular Extrasystoles 1/1/2009 Male 4/6/2009 Consumer
Primary
Concomitant
Respiratory Failure Hospitalization 11/21/2008 Male 207 lb 4/7/2009 Physician Australia
Primary
Concomitant
Stomatitis Other Serious 1/1/2004 Female 4/21/2009 Lawyer United States
Primary
Secondary
Concomitant
Feeling Abnormal 63 Male 180 lb 4/22/2009 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 4/22/2009 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Required Intervention 12/3/2008 61 Male 12/5/2008 Pharmacist United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 4/20/2009 Male 5/7/2009 Other Health Professional United States
Primary
Concomitant
Retching Other Serious 11/12/2008 Female 5/8/2009 Consumer United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 3/4/2009 77 Female 125 lb 5/7/2009 Physician United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 3/4/2009 77 Female 125 lb 5/20/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 5/29/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 2/24/2009 69 Male 200 lb 6/1/2009 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 4/20/2009 Male 6/9/2009 Other Health Professional United States
Primary
Concomitant
Silicon Granuloma Hospitalization 53 Female 7/9/2009 Physician United States
Primary
Secondary
Neuropathy Peripheral Other Serious 1/1/1999 40 Female 134 lb 7/16/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 5/2/2000 43 Female 270 lb 7/16/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/16/2009 Consumer United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 1/1/2004 Female 7/20/2009 Lawyer United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/3/2009 Female 7/28/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/29/2009 Consumer United States
Primary
Secondary
Concomitant
Wound Abscess Other Serious 1/9/2009 Male 8/3/2009 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 50 Female 120 lb 8/4/2009 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/4/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/13/2006 65 Female 167 lb 8/5/2009 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased 9/1/2008 67 Male 8/22/2009 Consumer United States
Primary
Concomitant

Drug Data