Alprazolam combined with Tramadol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypotension Hospitalization 3/1/2007 58 Female 8/10/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 9/26/2007 55 Female 11/6/2007 Other Health Professional France
Primary
Concomitant
Lung Neoplasm Malignant Death 10/1/2008 12/11/2008 Consumer Peru
Primary
Concomitant
Drug Toxicity Death 42 Female 12/29/2008 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 42 Female 12/29/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 11/24/2008 63 Female 1/7/2009 Physician United States
Primary
Concomitant
Completed Suicide Death 11/24/2008 63 Female 1/22/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 50 Male 222 lb 4/3/2009 United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 Female 222 lb 5/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 1/1/2002 Female 222 lb 5/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 Female 222 lb 6/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/20/2008 Female 110 lb 7/9/2009 Spain
Primary
Concomitant
Hypersensitivity Other Serious 5/30/2009 57 Female 180 lb 7/10/2009 United States
Primary
Concomitant
Wheelchair User Disability 3/1/2009 Male 7/9/2009 United States
Primary
Concomitant
Surgery Death 73 Female 7/13/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/29/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 72 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Papilloedema Hospitalization 7/9/2009 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/13/2006 65 Female 167 lb 8/5/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 12/6/2007 72 Female 8/5/2009 United States
Primary
Concomitant
Papilloedema Hospitalization 7/9/2009 Female 8/14/2009 Physician Switzerland
Primary
Secondary
Concomitant
Thrombosis Other Serious 54 Male 200 lb 8/20/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 6/27/2009 Male 8/20/2009 Other Health Professional United States
Primary
Secondary
Vomiting 8/13/2008 Male 240 lb 8/21/2009 Consumer United States
Primary
Concomitant
Pruritus 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Pain Hospitalization 7/14/2007 77 Female 10/16/2009 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 61 Female 10/17/2009 Lawyer United States
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 53 Female 12/11/2009 United States
Primary
Concomitant
Visual Impairment Hospitalization 59 Female 12/11/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 77 Female 12/11/2009 United States
Primary
Concomitant
Thyroid Cyst Hospitalization 11/2/2007 78 Female 12/11/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 9/1/2009 58 Female 1/5/2010 Consumer United States
Primary
Concomitant
Completed Suicide Death 1/1/2008 36 Male 1/14/2010 Physician United States
Primary
Secondary
Weight Decreased Other Serious 12/1/2003 Male 159 lb 1/19/2010 Physician United States
Primary
Concomitant
Wound Hospitalization 2/20/2006 Female 1/15/2010 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 7/14/2007 77 Female 1/12/2010 United States
Primary
Concomitant
Drug Toxicity Death 36 Male 1/22/2010 Physician United States
Primary
Secondary
Completed Suicide Death 36 Male 1/18/2010 United States
Primary
Secondary
Concomitant
Drug Abuse Death 50 Male 1/20/2010 United States
Primary
Secondary
Eye Pain Other Serious 1/15/2010 43 Male 390 lb 1/26/2010 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 77 Female 1/22/2010 United States
Primary
Concomitant
Parkinson's Disease Other Serious 2/1/2010 80 Female 182 lb 2/8/2010 Physician United States
Primary
Concomitant
Completed Suicide Death 1/1/2008 36 Male 2/15/2010 Physician United States
Primary
Secondary
Weight Decreased Other Serious 12/1/2003 Male 159 lb 2/15/2010 Physician United States
Primary
Concomitant
Dehydration Death 3/14/2010 Male 172 lb 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 4/1/2010 31 Female 5/6/2010 Other Health Professional United States
Primary
Concomitant
Tongue Disorder Other Serious 57 Female 6/1/2010 Consumer United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 2/3/2008 36 Female 216 lb 6/2/2010 Physician United States
Primary
Concomitant
Vertebral Foraminal Stenosis Other Serious 8/1/2000 58 Female 6/2/2010 United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 2/3/2008 36 Female 216 lb 6/3/2010 Physician United States
Primary
Concomitant
Abnormal Sensation In Eye Female 135 lb 5/11/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 9/1/2009 58 Female 6/8/2010 Physician United States
Primary
Concomitant
Serotonin Syndrome Other Serious 3/17/2008 28 Female 6/21/2010
Primary
Secondary
Abdominal Pain Upper 11/1/2006 63 Female 126 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Sinusitis 12/1/2006 57 Female 240 lb 7/8/2010 Consumer United States
Primary
Concomitant
Tumour Haemorrhage Hospitalization 5/22/2010 82 Female 366 lb 7/9/2010 Physician United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 8/1/2000 58 Female 7/15/2010 United States
Primary
Secondary
Concomitant
Neutrophil Count Increased Hospitalization 1/11/2010 51 Male 168 lb 7/16/2010 Physician Belgium
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/19/2010 Physician Belgium
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/20/2010 Physician Belgium
Primary
Secondary
Concomitant
Vein Pain Other Serious 2/11/2010 62 Female 199 lb 7/22/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 3/12/2010 79 Female 177 lb 7/22/2010 Physician United States
Primary
Concomitant
Urticaria 11/10/2008 47 Male 190 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 12/8/2008 37 Female 216 lb 8/16/2010 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 12/8/2008 37 Female 216 lb 8/17/2010 Physician United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 8/1/2000 58 Female 8/17/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/20/2008 89 Female 110 lb 8/17/2010 Physician Spain
Primary
Concomitant
Osteoarthritis Other Serious 5/1/2007 52 Female 8/20/2010 Physician United States
Primary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 8/23/2010 Consumer United States
Primary
Secondary
Concomitant
Viith Nerve Paralysis Other Serious 8/1/2000 58 Female 8/23/2010 United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 8/24/2010 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 11/1/2008 51 Male 9/14/2010 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2010 78 Female 177 lb 9/16/2010 Physician United States
Primary
Concomitant
Vomiting 5/3/2010 41 Female 245 lb 9/17/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 21 Male 9/17/2010 Physician United States
Primary
Secondary
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 9/3/2010 United States
Primary
Concomitant
Splenic Haemorrhage Other Serious 2/3/2009 60 Female 157 lb 9/20/2010 Physician Czech Republic
Primary
Concomitant
Dermatitis Exfoliative Other Serious 5/21/2010 59 Male 163 lb 9/28/2010 Physician Netherlands
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2003 79 Male 159 lb 9/29/2010 United States
Primary
Secondary
Concomitant
Product Quality Issue 68 Male 10/13/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 10/12/2009 12/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Convulsion Other Serious Male 245 lb 12/7/2010 Pharmacist United States
Primary
Secondary
Concomitant
Abdominal Discomfort Other Serious 10/12/2009 23 Female 121 lb 1/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2009 68 Female 1/7/2011 Physician United States
Primary
Secondary
Drug Abuse Death 1/1/2009 23 Male 1/7/2011 Physician United States
Primary
Secondary
Accidental Exposure Death 1/1/2009 50 Male 1/10/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 50 Male 1/14/2011 Physician United States
Primary
Secondary
Death Death 68 Female 1/14/2011 Physician United States
Primary
Secondary
Cough 10/1/2010 71 Male 1/14/2011 Consumer
Primary
Concomitant
Toxicity To Various Agents Death 68 Female 1/14/2011 Physician United States
Primary
Secondary
Drug Abuse Death 23 Male 1/20/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 68 Female 1/25/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 68 Female 1/25/2011 Physician United States
Primary
Secondary
Hypotension Other Serious 21 Male 2/3/2011 Physician United States
Primary
Secondary
Poisoning Death 1/1/2009 23 Male 1/27/2011 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 68 Female 1/20/2011 United States
Primary
Secondary
Accidental Exposure Death 50 Male 1/20/2011 United States
Primary
Secondary
Accidental Exposure Death 1/1/2009 50 Male 1/27/2011 Physician United States
Primary
Secondary
Accidental Exposure Death 1/1/2009 50 Male 2/10/2011 Physician United States
Primary
Secondary
Drug Abuse Death 23 Male 2/11/2011 Physician United States
Primary
Secondary
Myocardial Infarction Other Serious 1/1/2011 53 Female 151 lb 3/2/2011 Consumer United States
Primary
Secondary
Concomitant
Scoliosis Disability 12/1/2003 79 Male 159 lb 3/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cough 10/1/2010 71 Male 3/10/2011 Consumer United States
Primary
Concomitant
Oropharyngeal Pain 2/7/2011 75 Female 3/14/2011 Consumer United States
Primary
Concomitant
Hypertension Other Serious 1/1/2011 53 Female 151 lb 3/14/2011 Physician United States
Primary
Secondary
Concomitant
Drug Administration Error Death 3/18/2011 Other Health Professional Australia
Primary
Secondary
Abdominal Pain Upper Other Serious 9/1/2008 29 Female 175 lb 3/22/2011 Physician United States
Primary
Secondary
Concomitant
Extranodal Marginal Zone B-cell Lymphoma (Malt Type) Other Serious 11/15/2010 40 Female 3/29/2011 Other Health Professional United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death 3/8/2011 76 Female 3/29/2011 Other Health Professional United States
Primary
Concomitant
Peritonitis Death 3/14/2010 56 Male 172 lb 4/1/2011 Physician Hungary
Primary
Secondary
Concomitant
Pneumonia Death 6/18/2010 42 Female 137 lb 4/6/2011 Consumer Brazil
Primary
Concomitant
Ventricular Tachycardia Hospitalization 41 Female 170 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/1/2004 41 Female 145 lb 4/8/2011 Consumer United States
Primary
Concomitant
Abasia Other Serious 10/1/2009 70 Male 235 lb 4/11/2011 Consumer United States
Primary
Secondary
Concomitant
Overdose Death 11/9/2010 56 Female 150 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 11/9/2010 56 Female 150 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 11/9/2010 56 Female 150 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 11/9/2010 56 Female 150 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 11/9/2010 56 Female 150 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 11/9/2010 56 Female 150 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 11/9/2010 56 Female 150 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 11/9/2010 56 Female 150 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Coma Other Serious Female 4/26/2011 Physician Ireland
Primary
Concomitant
Arthralgia Hospitalization 11/29/2010 32 Female 115 lb 4/29/2011 Physician Belgium
Primary
Concomitant
Homicide Death 54 Male 5/3/2011 Physician United States
Primary
Secondary
Bronchospasm 10/1/2010 71 Male 5/3/2011 Physician United States
Primary
Concomitant
Anger Other Serious 6/1/2009 40 Male 5/6/2011 Lawyer United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 12/8/2008 37 Female 216 lb 5/4/2011 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 3/19/2009 27 Female 200 lb 5/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 3/19/2009 27 Female 200 lb 5/4/2011 Consumer United States
Primary
Secondary
Concomitant
Back Pain Other Serious 3/13/2011 66 Female 6/16/2011 Consumer United States
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 3/13/2011 66 Female 7/11/2011 Consumer United States
Primary
Secondary
Concomitant
Neck Injury Other Serious 4/1/2009 41 Female 8/9/2011 Lawyer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/2010 36 Female 235 lb 9/9/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious 1/1/2010 36 Female 235 lb 9/12/2011 Consumer United States
Primary
Secondary
Concomitant
Oropharyngeal Pain Hospitalization 8/5/2011 47 Female 79 lb 9/15/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/5/2011 47 Female 79 lb 9/29/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Pain 12/1/2011 38 Male 375 lb 12/27/2011 Consumer United States
Primary
Concomitant
Pain Other Serious 46 Female 168 lb 2/23/2012 Consumer Brazil
Primary
Concomitant
Thrombocytopenia Hospitalization 8/18/2011 66 Male 239 lb 3/7/2012 Physician United States
Primary
Secondary
Concomitant
Mastication Disorder Hospitalization 8/1/2000 58 Female 4/30/2012 Lawyer United States
Primary
Secondary
Concomitant
Contusion Other Serious 1/1/2012 56 Female 120 lb 5/25/2012 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2012 56 Female 119 lb 5/29/2012 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2012 56 Female 119 lb 6/4/2012 Consumer United States
Primary
Secondary
Concomitant
Infarction Hospitalization 7/1/2012 66 Female 130 lb 8/16/2012 Consumer Brazil
Primary
Secondary
Concomitant
Infarction Hospitalization 1/1/2011 65 Female 130 lb 8/16/2012 Consumer Brazil
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious Female 200 lb 10/19/2012 Lawyer Us
Primary
Concomitant
Tremor Other Serious Female 140 lb 11/12/2012 Lawyer Us
Primary
Concomitant
Unevaluable Event Disability Female 10/8/2012 Lawyer Us
Primary
Concomitant
Wound Other Serious 8/1/2000 58 Female 11/12/2012 Consumer Us
Primary
Secondary
Concomitant

Drug Data