Alprazolam combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Restlessness 8/1/2005 45 Female 2/8/2006 Consumer United States
Primary
Concomitant
Initial Insomnia 1/1/2005 47 Female 130 lb 1/5/2006 Consumer United States
Primary
Concomitant
Vertigo Other Serious 12/1/2002 63 Female 150 lb 3/1/2006 Physician United States
Primary
Concomitant
Mood Swings Other Serious 9/1/2005 Female 140 lb 1/20/2006 United States
Primary
Concomitant
Paraesthesia Other Serious 9/1/2005 Female 4/26/2006 Physician Belgium
Primary
Concomitant
Drug Ineffective 12/1/2005 49 Female 7/12/2006 Consumer United States
Primary
Concomitant
Joint Swelling Other Serious 4/1/2006 45 Female 146 lb 7/19/2006 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 6/1/2005 58 Male 7/14/2006 Physician United States
Primary
Concomitant
Syncope Hospitalization 12/1/2005 Female 230 lb 9/26/2006 Consumer United States
Primary
Concomitant
Suicide Attempt Required Intervention 6/10/1998 18 Female 10/5/2006 United States
Primary
Secondary
Concomitant
Pain Required Intervention 1/1/2004 Female 10/19/2006 Lawyer United States
Primary
Concomitant
Paraesthesia Other Serious 9/1/2005 Female 11/27/2006 Physician Belgium
Primary
Concomitant
Suicidal Ideation Hospitalization 9/27/2006 36 Female 12/13/2006 Consumer United States
Primary
Concomitant
Syncope Hospitalization 12/1/2005 Female 230 lb 12/14/2006 Consumer United States
Primary
Concomitant
Visual Disturbance Hospitalization 4/12/2006 37 Male 275 lb 12/6/2006 Consumer United States
Primary
Concomitant
Tendon Disorder Female 10/19/2006 United States
Primary
Concomitant
Tardive Dyskinesia Hospitalization 11/29/2006 Female 215 lb 12/22/2006 Pharmacist United States
Primary
Concomitant
Pain Other Serious 1/1/2004 Female 1/22/2007 Lawyer United States
Primary
Concomitant
Visual Disturbance Hospitalization 1/1/2006 37 Male 275 lb 2/20/2007 Consumer United States
Primary
Concomitant
Tongue Eruption 7/28/2006 58 Male 165 lb 2/28/2007 Consumer United States
Primary
Concomitant
Syncope Other Serious 12/18/2002 Female 3/8/2007 Consumer United States
Primary
Concomitant
Syncope Other Serious 12/18/2002 Female 3/20/2007 Lawyer United States
Primary
Concomitant
Suicide Attempt Required Intervention 1/1/2004 57 Female 158 lb 8/21/2004 United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious Female 267 lb 5/2/2007 Lawyer United States
Primary
Concomitant
Wheezing Other Serious 1/1/2007 Female 170 lb 6/8/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2007 195 lb 6/21/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2007 Female 191 lb 7/20/2007 Physician United States
Primary
Concomitant
Muscular Weakness Hospitalization 1/1/2005 Female 160 lb 7/24/2007 Consumer United States
Primary
Secondary
Concomitant
Urticaria Other Serious 1/1/2007 Female 189 lb 8/16/2007 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2004 24 Female 181 lb 9/18/2007 Physician United States
Primary
Concomitant
Drug Ineffective 10/19/2006 Female 212 lb 11/29/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 8/19/2002 47 Female 246 lb 10/9/2007 Lawyer United States
Primary
Concomitant
Speech Disorder Other Serious 1/3/2008 Female 1/16/2008 Consumer United States
Primary
Concomitant
Drug Exposure During Pregnancy Female 2/7/2008 Consumer United States
Primary
Concomitant
Skin Discolouration Death 12/15/2007 33 Male 2/25/2008 Physician Brazil
Primary
Secondary
Concomitant
Skin Discolouration Death 12/15/2007 33 Male 2/25/2008 Physician Brazil
Primary
Secondary
Concomitant
Skin Discolouration Death 12/15/2007 33 Male 2/25/2008 Physician Brazil
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/1/2001 Female 150 lb 2/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Skin Discolouration Death 12/15/2007 33 Male 3/1/2008 Physician Brazil
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/1/2001 Female 150 lb 3/4/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased 51 Female 211 lb 3/7/2008 Consumer United States
Primary
Concomitant
Somnambulism Female 3/31/2008 Physician
Primary
Concomitant
Weight Increased Hospitalization 8/1/2001 Female 150 lb 4/1/2008 Pharmacist United States
Primary
Secondary
Concomitant
Swelling Other Serious Female 5/23/2008 United States
Primary
Concomitant
Wrong Drug Administered Other Serious 6/1/2008 43 Male 7/23/2008 Pharmacist United States
Primary
Concomitant
Rectal Prolapse Hospitalization 5/1/2008 39 Female 7/31/2008 Physician United States
Primary
Concomitant
Paraesthesia Male 145 lb 8/27/2008 United States
Primary
Concomitant
Intentional Overdose Other Serious 8/26/2008 9/8/2008 Physician Brazil
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Other Serious 2/22/2008 Male 169 lb 9/19/2008 Physician United States
Primary
Concomitant
Thyroid Function Test Abnormal Other Serious 2/22/2008 Male 169 lb 9/29/2008 Physician United States
Primary
Concomitant
Swelling Face Other Serious Female 10/31/2008 United States
Primary
Concomitant
Thyroid Function Test Abnormal Other Serious 2/22/2008 Male 168 lb 11/3/2008 Physician United States
Primary
Concomitant
Thyroid Function Test Abnormal Other Serious 2/22/2008 Male 168 lb 11/17/2008 Physician United States
Primary
Concomitant
Vomiting 4/1/2008 Female 143 lb 12/2/2008 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2008 53 Female 12/4/2008 Consumer United States
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Other Serious 2/22/2008 Male 168 lb 12/23/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 192 lb 1/6/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 192 lb 1/13/2009 Consumer United States
Primary
Concomitant
Live Birth 33 Female 135 lb 2/9/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 192 lb 2/10/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 2/10/2009 63 Female 107 lb 2/25/2009 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/13/2009 Female 3/16/2009 Physician United States
Primary
Concomitant
Loss Of Consciousness Death 1/13/2009 Female 3/20/2009 Other Health Professional United States
Primary
Secondary
Unresponsive To Stimuli Death 1/13/2009 58 Female 3/17/2009 Physician United States
Primary
Secondary
Multiple Drug Overdose Accidental Death 1/13/2009 58 Female 3/23/2009 Physician United States
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 10/10/2007 Male 190 lb 3/27/2009 Consumer
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 10/10/2007 Male 190 lb 3/30/2009 Consumer
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 11/5/2002 39 Male 4/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 10/10/2007 Male 190 lb 4/8/2009 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious Male 190 lb 4/14/2009 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious Male 190 lb 4/16/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/28/2009 16 Female 97 lb 4/15/2009 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 8/6/2001 25 Male 256 lb 5/21/2009 United States
Primary
Concomitant
Death Death 3/30/2008 61 Female 5/22/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/1/2004 42 Female 6/2/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/1/2003 40 Male 312 lb 6/15/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 12/11/2003 23 Female 196 lb 6/15/2009 United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2008 43 Female 6/29/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/23/2009 16 Female 97 lb 7/7/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 6/25/2002 49 Male 192 lb 7/14/2009 United States
Primary
Concomitant
Obesity Other Serious 1/1/2003 37 Female 199 lb 7/15/2009 United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/1999 40 Female 134 lb 7/16/2009 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 11/5/2002 37 Male 220 lb 8/3/2009 United States
Primary
Concomitant
Product Quality Issue Other Serious 6/1/2009 Female 220 lb 7/27/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2001 54 Female 216 lb 8/26/2009 United States
Primary
Concomitant
Pneumonia Hospitalization 5/1/2007 Female 9/1/2009 Consumer
Primary
Concomitant
Pneumonia Hospitalization 5/1/2007 Female 9/4/2009 Consumer
Primary
Concomitant
Weight Increased 51 Female 211 lb 9/2/2009 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 6/2/2009 38 Female 146 lb 9/14/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 5/1/2007 Female 9/17/2009 Physician
Primary
Concomitant
Obesity 1/1/2001 35 Female 195 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 1/1/2000 24 Female 317 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 5/1/2003 45 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Diabetes Mellitus 1/1/2005 38 Female 9/23/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 46 Female 223 lb 9/25/2009 United States
Primary
Concomitant
Conversion Disorder Other Serious Female 10/16/2009 Physician United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/22/2009 Lawyer United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/27/2009 Lawyer United States
Primary
Concomitant
Vertigo Required Intervention 9/20/2001 42 Female 155 lb 11/4/2009 United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 6/2/2009 38 Female 146 lb 11/23/2009 Other Health Professional United States
Primary
Concomitant
Arteriosclerosis Death 61 Female 220 lb 12/2/2009 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/13/2009 Female 12/1/2009 Physician United States
Primary
Concomitant
Prosthesis User Hospitalization 9/6/2009 Female 1/4/2010 Physician Canada
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2006 48 Female 172 lb 1/8/2010 United States
Primary
Concomitant
Vomiting Other Serious 3/30/2004 51 Male 390 lb 1/13/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2006 48 Female 172 lb 1/13/2010 United States
Primary
Concomitant
Refusal Of Treatment By Patient Life Threatening 59 Female 1/15/2010 United States
Primary
Concomitant
Visual Impairment Other Serious 11/1/2009 Female 121 lb 3/5/2010 Consumer Japan
Primary
Concomitant
Weight Increased 51 Female 211 lb 3/5/2010 Other Health Professional United States
Primary
Concomitant
Thyroid Neoplasm Hospitalization 6/2/2009 38 Female 146 lb 3/9/2010 Other Health Professional United States
Primary
Concomitant
Skin Discolouration Death 12/15/2007 33 Male 4/5/2010 Physician Brazil
Primary
Secondary
Concomitant
Vomiting Other Serious 5/1/2008 38 Female 128 lb 4/13/2010 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 5/22/2002 49 Male 192 lb 4/16/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2010 38 Female 4/23/2010 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2001 54 Female 205 lb 4/29/2010 United States
Primary
Concomitant
Arteriosclerosis Death 61 Female 220 lb 5/3/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Disability 1/1/2007 35 Female 160 lb 5/5/2010 United States
Primary
Secondary
Concomitant
Urticaria 1/17/2010 53 Female 4/19/2010 Physician United States
Primary
Concomitant
Pollakiuria Female 5/11/2010 Other Health Professional United States
Primary
Concomitant
Pharyngeal Oedema Other Serious 11/1/2008 56 Female 195 lb 6/8/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2001 54 Female 205 lb 6/21/2010 United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 4/29/2005 35 Female 170 lb 7/2/2010 United States
Primary
Concomitant
Cholelithiasis Hospitalization 4/30/2008 27 Female 220 lb 7/19/2010 Physician United States
Primary
Secondary
Concomitant
Cholelithiasis Hospitalization 4/30/2008 27 Female 220 lb 7/21/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 34 Female 216 lb 8/2/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 7/1/2007 43 Female 123 lb 8/3/2010 Consumer United States
Primary
Concomitant
Syncope Other Serious 12/18/2002 65 Female 8/6/2010 Consumer United States
Primary
Concomitant
Violence-related Symptom Other Serious 7/1/2007 43 Female 123 lb 8/18/2010 Consumer United States
Primary
Concomitant
Weight Increased 51 Female 211 lb 9/1/2010 Other Health Professional United States
Primary
Concomitant
Unevaluable Event 4/9/2009 42 Female 139 lb 9/9/2010 Consumer United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 1/1/2008 32 Female 154 lb 9/13/2010 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2006 59 Female 157 lb 9/13/2010 Consumer United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 1/1/2008 32 Female 154 lb 9/14/2010 Physician United States
Primary
Concomitant
Pharyngeal Oedema Other Serious 11/1/2008 56 Female 195 lb 9/16/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 11/24/2009 58 Female 130 lb 9/24/2010 Physician United States
Primary
Concomitant
Condition Aggravated Other Serious 45 Female 10/12/2010 Physician
Primary
Secondary
Concomitant
Mental Disorder Other Serious 45 Female 10/13/2010 Physician United States
Primary
Secondary
Mental Disorder Other Serious 45 Female 10/29/2010 Physician United States
Primary
Secondary
Mental Disorder Other Serious 45 Female 10/29/2010 Physician United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 11/3/2010 Physician United States
Primary
Secondary
Urinary Tract Disorder Other Serious 9/28/2010 70 Female 10/26/2010 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2008 32 Female 154 lb 11/12/2010 Physician United States
Primary
Secondary
Concomitant
Mental Disorder Other Serious 45 Female 11/24/2010 Physician United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 11/8/2010 United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 12/1/2010 Other Health Professional United States
Primary
Secondary
Swelling Other Serious 61 Female 220 lb 12/1/2010 Other Health Professional United States
Primary
Concomitant
Cough 73 Female 187 lb 12/14/2010 Consumer United States
Primary
Concomitant
Pharyngeal Oedema Other Serious 11/1/2008 56 Female 195 lb 6/8/2010 Consumer United States
Primary
Concomitant
Fatigue Other Serious 10/1/2009 62 Female 241 lb 1/4/2011 Consumer United States
Primary
Concomitant
Palpitations Other Serious 7/1/2007 43 Female 123 lb 1/27/2011 Consumer United States
Primary
Concomitant

Drug Data