Alprazolam combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pain In Extremity Hospitalization 6/1/2005 Female 1/31/2006 Consumer United States
Primary
Concomitant
Syncope Hospitalization 12/28/2005 65 Female 3/31/2006 Switzerland
Primary
Secondary
Concomitant
Death Death 3/1/2006 51 Female 4/12/2006 United States
Primary
Concomitant
Weight Decreased Hospitalization 3/28/2006 60 Male 212 lb 4/13/2006 Physician United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 4/13/2006 76 Male 160 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/8/2002 56 Female 154 lb 5/3/2006 Physician United States
Primary
Concomitant
Death Death 3/28/2006 51 Female 5/1/2006 United States
Primary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 1/27/2006 76 Female 209 lb 7/7/2006 Other Health Professional France
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 9/9/2005 46 Male 1/13/2006 United States
Primary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 159 lb 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Very Low Density Lipoprotein Increased Other Serious 43 Female 174 lb 10/13/2006 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 8/30/2006 47 Female 152 lb 12/13/2006 Physician Brazil
Primary
Secondary
Hepatitis Fulminant Hospitalization 9/9/2006 30 Male 104 lb 12/15/2006 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 9/9/2006 30 Male 104 lb 12/19/2006 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Headache 9/2/2006 76 Female 202 lb 10/24/2006 United States
Primary
Concomitant
Transaminases Increased Hospitalization 1/5/2007 77 Male 203 lb 3/1/2007 Consumer France
Primary
Secondary
Concomitant
Fasciitis Hospitalization 1/1/2007 Male 203 lb 3/9/2007 Other Health Professional France
Primary
Concomitant
Pulmonary Hypertension 3/1/2006 65 Female 152 lb 1/23/2007 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 8/3/2006 66 Female 5/4/2007 Physician Austria
Primary
Concomitant
Vasospasm Hospitalization 84 Female 6/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia 3/7/2007 66 Female 150 lb 6/25/2007 Consumer United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 1/26/2007 82 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 6/5/2007 66 Male 6/29/2007 Consumer United States
Primary
Concomitant
Sinus Bradycardia Life Threatening 84 Female 7/6/2007 Germany
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 84 Female 7/17/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/1/2004 41 Female 147 lb 11/19/2007 Physician United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2004 Female 103 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/21/2007 76 Female 12/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Procedural Nausea Other Serious 1/1/2007 Female 161 lb 12/31/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/21/2007 76 Female 12/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Cord Compression Other Serious 3/1/2006 62 Female 125 lb 2/25/2008 Consumer United States
Primary
Concomitant
Cellulitis Other Serious 1/1/2006 Female 265 lb 4/30/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2007 Female 245 lb 5/2/2008 Physician United States
Primary
Concomitant
Tachycardia Other Serious 39 Female 5/13/2008 Physician United States
Primary
Concomitant
Scratch Other Serious 1/1/2004 Female 120 lb 5/16/2008 United States
Primary
Concomitant
Scratch Other Serious 1/1/2004 Female 120 lb 5/23/2008 United States
Primary
Concomitant
Premature Labour Other Serious 10/31/2007 Female 157 lb 6/9/2008 United States
Primary
Concomitant
Oedema Peripheral Hospitalization 9/26/2007 Female 223 lb 7/3/2008 Other Health Professional United States
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 39 Female 7/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Uterine Leiomyoma Other Serious 1/1/1998 Female 150 lb 7/15/2008 United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 4/1/1998 Female 7/9/2008 India
Primary
Secondary
Concomitant
Vomiting Other Serious 4/21/2008 66 Male 155 lb 7/10/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2007 73 Female 8/12/2008 Pharmacist Spain
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2007 73 Female 8/21/2008 Pharmacist Spain
Primary
Secondary
Concomitant
Vomiting Other Serious 4/21/2008 66 Male 155 lb 8/27/2008 United States
Primary
Concomitant
Blister 5/12/2008 Female 188 lb 9/12/2008 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 4/21/2008 66 Male 155 lb 9/10/2008 United States
Primary
Concomitant
Malaise Hospitalization 8/5/2008 Female 9/23/2008 Other Health Professional France
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 6/27/2008 69 Female 9/12/2008 Physician Poland
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious Male 210 lb 10/3/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/21/2008 53 Male 282 lb 10/22/2008 Physician United States
Primary
Secondary
Concomitant
Ulcer Haemorrhage Other Serious 1/1/2008 78 Female 10/31/2008 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 10/13/2008 53 Male 170 lb 10/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 10/24/2008 Male 220 lb 11/4/2008 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 10/21/2008 53 Male 282 lb 11/3/2008 Physician United States
Primary
Secondary
Concomitant
Hospitalisation Death 10/24/2008 Male 220 lb 11/10/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 9/21/2008 Male 282 lb 11/17/2008 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity 10/1/2008 Female 11/26/2008 United States
Primary
Concomitant
Vomiting Other Serious 9/21/2008 Male 282 lb 12/1/2008 Physician United States
Primary
Secondary
Concomitant
Stent Placement Hospitalization 67 Male 12/2/2008 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 9/1/2008 65 Female 128 lb 12/5/2008 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 10/16/2008 Male 227 lb 12/10/2008 Other Health Professional United States
Primary
Concomitant
Nervousness 85 Female 156 lb 12/17/2008 Consumer United States
Primary
Concomitant
Stent Placement Hospitalization 10/26/2008 67 Male 12/22/2008 Consumer United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 10/16/2008 Male 227 lb 12/29/2008 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 1/11/2009 Female 1/20/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Death 1/1/2009 Female 1/22/2009 Physician United States
Primary
Concomitant
Liver Function Test Abnormal 12/5/2008 Male 2/24/2009 United States
Primary
Concomitant
Visual Impairment Disability 10/1/2008 66 Female 151 lb 3/17/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 1/1/1996 45 Male 4/2/2009 United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 77 Female 3/26/2009 Physician Italy
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/16/2007 64 Female 128 lb 5/1/2009 Lawyer United States
Primary
Concomitant
Breast Cancer Other Serious 4/30/2004 53 Female 139 lb 5/19/2009 Consumer United States
Primary
Secondary
Concomitant
Upper Limb Fracture Hospitalization 66 Female 6/5/2009 Lawyer United States
Primary
Concomitant
Dizziness 2/1/2009 Male 6/12/2009 Pharmacist United States
Primary
Concomitant
Somnolence Required Intervention 4/10/2009 52 Male 203 lb 4/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Social Avoidant Behaviour Other Serious 84 Female 7/3/2009 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Life Threatening 6/24/2009 58 Female 7/10/2009 Consumer United States
Primary
Secondary
Concomitant
Surgery Death 73 Female 7/13/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 47 Male 283 lb 7/21/2009 United States
Primary
Concomitant
Torsade De Pointes Life Threatening 5/28/2009 Male 7/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 5/23/2009 Male 7/24/2009 Other Health Professional France
Primary
Concomitant
Interacting
Vomiting Hospitalization 65 Female 167 lb 7/22/2009 Lawyer United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 6/1/2009 Male 8/12/2009 Portugal
Primary
Concomitant
Vomiting Hospitalization 10/13/2006 65 Female 167 lb 8/5/2009 Lawyer United States
Primary
Concomitant
Nausea Hospitalization 64 Female 8/11/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Vertigo Hospitalization 74 Female 8/18/2009 United States
Primary
Concomitant
Nausea Hospitalization 64 Female 8/20/2009 Lawyer United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 6/1/2009 Male 8/28/2009 Portugal
Primary
Concomitant
Wheezing Hospitalization 45 Male 8/25/2009 United States
Primary
Concomitant
Weight Decreased Death 73 Female 8/28/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 65 Female 155 lb 8/24/2009 United States
Primary
Concomitant
Vertigo Hospitalization 74 Female 9/2/2009 United States
Primary
Concomitant
Stent Placement Hospitalization 10/26/2008 67 Male 9/14/2009 Consumer United States
Primary
Secondary
Concomitant
Injury Other Serious 62 Male 200 lb 9/8/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/21/2007 78 Female 9/11/2009 Lawyer United States
Primary
Concomitant
Ventricular Failure Hospitalization 49 Female 9/14/2009 United States
Primary
Concomitant
Tinnitus 1/1/1998 64 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Tremor Required Intervention 7/21/2009 65 7/22/2009 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 64 Female 155 lb 9/17/2009 United States
Primary
Concomitant
Mobility Decreased Hospitalization 7/1/2008 54 Male 9/28/2009
Primary
Concomitant
Weight Increased Hospitalization 72 Male 9/21/2009 United States
Primary
Concomitant
Vertigo Hospitalization 74 Female 9/23/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 4/17/2009 Male 168 lb 10/2/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 53 Female 9/29/2009 United States
Primary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 9/24/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 46 Female 223 lb 9/25/2009 United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 66 Female 9/24/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 60 Female 9/29/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/12/2009 United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 66 Female 10/17/2009 United States
Primary
Concomitant
Ventricular Failure Hospitalization 49 Female 10/16/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 12/10/2006 83 Male 10/16/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 74 Female 164 lb 10/20/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 72 Male 10/22/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/21/2007 79 Female 10/22/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/10/2006 83 Male 10/22/2009 Consumer United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/22/2009 Lawyer United States
Primary
Concomitant
Generalised Oedema Hospitalization 7/1/2008 Male 11/2/2009 Other Health Professional United States
Primary
Secondary
Generalised Oedema Hospitalization 7/1/2008 Male 11/3/2009 Other Health Professional United States
Primary
Secondary
Wound Dehiscence Hospitalization 66 Female 10/26/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/26/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/21/2007 79 Female 10/26/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 72 Male 10/26/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 74 Female 164 lb 10/26/2009 United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/27/2009 Lawyer United States
Primary
Concomitant
Panic Attack Other Serious 62 Male 229 lb 10/26/2009 Lawyer United States
Primary
Concomitant
Vertigo Hospitalization 74 Female 164 lb 10/30/2009 United States
Primary
Concomitant
Haemorrhage Death 11/4/2009 Female 119 lb 11/11/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 7/21/2007 79 Female 11/4/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 72 Male 11/9/2009 Lawyer United States
Primary
Concomitant
Wound Dehiscence Hospitalization 66 Female 11/4/2009 United States
Primary
Concomitant
Unemployment Other Serious 62 Male 229 lb 11/4/2009 United States
Primary
Concomitant
Weight Decreased Death 73 Female 11/5/2009 United States
Primary
Concomitant
Vomiting Required Intervention 66 Male 11/10/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/20/2006 47 Male 275 lb 11/20/2009 United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 7/21/2007 79 Female 11/18/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 65 Male 11/20/2009 United States
Primary
Concomitant
Vomiting Hospitalization 12/10/2006 83 Male 11/17/2009 United States
Primary
Concomitant
Vertigo Hospitalization 74 Female 164 lb 11/17/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 72 Male 11/17/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 11/20/2009 United States
Primary
Concomitant

Drug Data