Alprazolam combined with Paroxetine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Swelling Face Life Threatening Female 5/4/2006 Other Health Professional Saudi Arabia
Primary
Concomitant
Disease Progression Death 11/21/2005 Male 5/17/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 53 Male 134 lb 5/19/2006 Consumer Brazil
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/1/2006 84 Female 132 lb 5/31/2006 Other Health Professional France
Primary
Secondary
Concomitant
Drug Toxicity Death 11/1/2004 48 Female 6/14/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/19/2006 48 Female 7/26/2006 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 29 Female 8/11/2006 Brazil
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2000 52 Female 143 lb 8/25/2006
Primary
Secondary
Concomitant
Neck Pain Other Serious 52 Female 143 lb 9/7/2006 Physician Austria
Primary
Concomitant
Weight Increased Other Serious 29 Female 9/8/2006 Brazil
Primary
Concomitant
Weight Increased Other Serious 29 Female 9/29/2006 Brazil
Primary
Concomitant
Psychomotor Retardation Other Serious 74 Male 10/13/2006 Japan
Primary
Secondary
Weight Increased Other Serious 29 Female 10/19/2006 Brazil
Primary
Secondary
Concomitant
Intentional Self-injury Death 11/9/2002 38 Male 180 lb 10/31/2006 United States
Primary
Concomitant
Drug Abuser Death 1/1/2005 30 11/22/2006 Physician United States
Primary
Secondary
Tension Other Serious 31 Female 11/30/2006 Other Health Professional United Kingdom
Primary
Secondary
Weight Increased Other Serious 29 Female 12/5/2006 Brazil
Primary
Secondary
Concomitant
Tremor Hospitalization 5/1/2006 43 Female 12/8/2006 Physician Japan
Primary
Secondary
Neuroleptic Malignant Syndrome Hospitalization 1/1/2006 74 Male 12/13/2006 Other Health Professional Japan
Primary
Secondary
Drug Screen Positive Hospitalization 10/18/2006 38 Female 155 lb 1/22/2007 United States
Primary
Secondary
Concomitant
Dystonia Hospitalization 59 Female 2/12/2007 Other Health Professional Spain
Primary
Concomitant
Angioedema Hospitalization 1/1/2006 59 Female 3/14/2007 Other Health Professional Spain
Primary
Concomitant
Completed Suicide Death 3/16/2007 Male 3/30/2007 Pharmacist United States
Primary
Secondary
Tension Other Serious 31 Female 4/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 48 Female 4/24/2007 Physician
Primary
Concomitant
Death Death 48 Female 4/26/2007 Physician
Primary
Concomitant
Somnolence Death 4/18/2002 Male 180 lb 5/8/2007 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 Female 165 lb 5/10/2007 Consumer Brazil
Primary
Secondary
Concomitant
Tension Other Serious 31 Female 5/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 53 Female 5/9/2007 Australia
Primary
Concomitant
Hepatocellular Damage Other Serious 38 Female 5/15/2007 Other Health Professional Spain
Primary
Secondary
Smoker Other Serious 5/1/2007 Female 152 lb 5/29/2007 Consumer United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 53 Female 5/30/2007 Physician Australia
Primary
Concomitant
Interacting
Tension Other Serious 31 Female 5/24/2007 United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 1/1/1998 64 Male 229 lb 6/22/2007 United States
Primary
Secondary
Concomitant
Papilloedema Death 5/1/2007 44 Male 165 lb 6/19/2007 Croatia (Local Name: Hrvatska)
Primary
Secondary
Pneumonia Hospitalization 9/10/2006 49 Female 6/13/2007 Physician United States
Primary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 44 Male 165 lb 7/5/2007 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Tooth Fracture Other Serious 1/1/2006 55 Female 7/12/2007 Other Health Professional United States
Primary
Concomitant
Visual Disturbance Hospitalization 53 Female 7/5/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 59 Female 7/10/2001 Physician Spain
Primary
Secondary
Concomitant
Skin Atrophy Other Serious 1/1/2006 Female 199 lb 7/20/2007 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective 69 Female 8/9/2007 Consumer United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 53 Female 8/8/2007 Australia
Primary
Secondary
Concomitant
Vertigo Hospitalization 44 Male 7/27/2007 Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Diabetic Foot Hospitalization 8/23/2007 80 Female 161 lb 8/30/2007 Physician Argentina
Primary
Concomitant
Varicose Vein Hospitalization 8/23/2007 80 Female 161 lb 9/13/2007 Physician Argentina
Primary
Concomitant
Vomiting Other Serious 5/1/2007 Male 9/27/2007 Other Health Professional France
Primary
Secondary
Concomitant
Varicose Vein Hospitalization 8/23/2007 80 Female 161 lb 10/3/2007 Physician Argentina
Primary
Concomitant
Tension Other Serious 31 Female 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Skin Atrophy Other Serious 9/19/2006 Female 199 lb 10/23/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 1/1/2006 55 Female 11/6/2007 Other Health Professional United States
Primary
Concomitant
Venous Thrombosis Other Serious 1/1/1998 64 Male 229 lb 11/15/2007 United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 1/1/2006 55 Female 11/21/2007 Other Health Professional United States
Primary
Concomitant
Vertigo Other Serious 44 Male 12/5/2007 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Irritability Other Serious 7/18/2007 Female 132 lb 12/31/2007 Pharmacist France
Primary
Concomitant
Interacting
Vertigo Other Serious 44 Male 12/21/2007 Croatia (Local Name: Hrvatska)
Primary
Secondary
Rales Hospitalization 4/21/2007 Female 188 lb 1/11/2008 Physician Denmark
Primary
Concomitant
Respiratory Arrest Death 1/1/2006 41 Male 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Death 41 Male 1/22/2008 Physician United States
Primary
Secondary
Drug Toxicity Death 3/1/2005 Female 194 lb 2/1/2008 Lawyer United States
Primary
Secondary
Concomitant
Pain In Extremity 8/17/2007 88 Female 2/7/2008 Consumer United States
Primary
Concomitant
Tooth Fracture Other Serious 1/1/2006 55 Female 2/21/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2007 52 Female 4/18/2008 Pharmacist Netherlands
Primary
Concomitant
Weight Decreased Other Serious 8/1/2007 52 Female 5/2/2008 Pharmacist Netherlands
Primary
Concomitant
Tooth Fracture Hospitalization 1/1/2006 55 Female 10/16/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 37 Female 12/23/2008 Physician Belgium
Primary
Concomitant
Metastasis Other Serious 68 Male 12/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stress Other Serious 1/1/2006 1/16/2009 Consumer Brazil
Primary
Secondary
Concomitant
Major Depression Other Serious 6/16/2008 2/23/2009 Other Health Professional France
Primary
Concomitant
Pneumonia Aspiration Hospitalization 37 7/28/2009 Other Health Professional France
Primary
Secondary
Suicidal Ideation Life Threatening 5/5/2009 57 Female 194 lb 8/4/2009 Physician United States
Primary
Secondary
Vomiting Hospitalization 72 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Sudden Death Death 11/14/2007 76 8/11/2009 Physician France
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/20/2005 44 Male 184 lb 8/13/2009 United States
Primary
Secondary
Concomitant
Liver Disorder Other Serious 36 8/31/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 46 Female 223 lb 9/25/2009 United States
Primary
Concomitant
Vomiting Hospitalization 8/30/2009 Female 10/8/2009 France
Primary
Secondary
Concomitant
Weight Increased Other Serious 23 Female 10/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 23 Female 10/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/22/2009 Lawyer United States
Primary
Concomitant
Drug Abuse Other Serious 50 Female 11/23/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Breast Cancer Other Serious 10/2/2003 Female 190 lb 11/24/2009 Lawyer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 16 Female 11/30/2009 Physician United States
Primary
Concomitant
Fracture Other Serious 10/13/2009 Female 12/3/2009 United States
Primary
Concomitant
Benign Prostatic Hyperplasia Other Serious 28 Male 11/29/2009 Physician Mexico
Primary
Concomitant
Urinary Tract Infection Hospitalization 77 Female 12/11/2009 United States
Primary
Concomitant
Vomiting Hospitalization 9/30/2009 Female 119 lb 12/24/2009 Physician France
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2008 23 Female 1/15/2010 Physician United States
Primary
Secondary
Large Intestine Perforation Other Serious 9/9/2009 Male 240 lb 1/21/2010 Consumer United States
Primary
Concomitant
Large Intestine Perforation Other Serious 9/7/2009 Male 240 lb 3/3/2010 Physician United States
Primary
Concomitant
Pyrexia Other Serious 9/1/2009 Male 240 lb 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/1/2008 97 Female 4/1/2010 Other Health Professional France
Primary
Secondary
Concomitant
Nausea Death 76 Male 3/29/2010 Physician France
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Other Serious 9/1/2008 97 Female 4/30/2010 Other Health Professional France
Primary
Secondary
Concomitant
Skin Disorder Other Serious 12/29/2009 53 Female 6/29/2010 Physician France
Primary
Concomitant
Drug Ineffective 11/1/2008 62 Male 6/29/2010 Other Health Professional United States
Primary
Concomitant
Gingival Recession 3/1/2009 55 Male 6/29/2010 Pharmacist United States
Primary
Concomitant
Vulvovaginal Dryness 8/1/2008 54 Female 6/30/2010 Pharmacist United States
Primary
Concomitant
Hepatitis Cholestatic Hospitalization 2/17/2010 65 Female 7/1/2010 Other Health Professional Spain
Primary
Concomitant
Interacting
Self Injurious Behaviour Other Serious 35 Female 8/9/2010 Physician Japan
Primary
Concomitant
Temperature Intolerance Other Serious 1/1/2009 19 Male 8/12/2010 Consumer Brazil
Primary
Secondary
Temperature Intolerance Other Serious 1/1/2009 19 Male 148 lb 8/24/2010 Consumer Brazil
Primary
Secondary
Concomitant
Thyroid Neoplasm Other Serious 6/17/2010 75 Male 378 lb 8/26/2010 Physician Korea, Republic Of
Primary
Concomitant
Drug Ineffective Other Serious 39 Female 9/3/2010 Other Health Professional India
Primary
Secondary
Thyroid Neoplasm Other Serious 6/17/2010 75 Male 378 lb 9/16/2010 Physician Korea, Republic Of
Primary
Concomitant
Serotonin Syndrome Hospitalization 73 Female 9/17/2010 Physician Greece
Primary
Secondary
Cerebral Haemorrhage Hospitalization 5/1/2009 48 Female 1/5/2011 Physician Czech Republic
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2009 80 Male 1/5/2011 Physician United States
Primary
Secondary
Respiratory Arrest Other Serious 1/1/2009 24 Male 1/6/2011 Physician United States
Primary
Secondary
Breast Cancer Female Other Serious 10/2/2003 61 Female 190 lb 1/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 6/6/2009 39 Female 130 lb 1/11/2011 Physician Poland
Primary
Concomitant
Abortion Spontaneous Other Serious 6/6/2009 39 Female 130 lb 1/18/2011 Physician Poland
Primary
Concomitant
Death Death Male 1/20/2011 Physician United States
Primary
Secondary
Completed Suicide Death 80 Male 1/21/2011 Physician United States
Primary
Secondary
Poisoning Death 1/1/2009 80 Male 1/21/2011 Physician United States
Primary
Secondary
Asthenia Disability 7/20/2010 76 Male 198 lb 2/7/2011 Consumer Hungary
Primary
Concomitant
Intentional Drug Misuse Death 1/1/2009 Male 1/25/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 24 Male 1/20/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 1/1/2009 Male 1/26/2011 Physician United States
Primary
Secondary
Completed Suicide Death 80 Male 1/21/2011 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2009 80 Male 1/21/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 1/1/2009 24 Male 1/27/2011 Physician United States
Primary
Secondary
Dyspnoea Hospitalization 3/1/2008 46 Female 275 lb 2/24/2011 Consumer United States
Primary
Concomitant
Cardio-respiratory Arrest Death Male 3/2/2011 Physician United States
Primary
Secondary
Completed Suicide Death 80 Male 3/4/2011 Other Health Professional United States
Primary
Secondary
Nausea Hospitalization 1/1/2007 30 Female 177 lb 3/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pernicious Anaemia Other Serious 1/1/2009 58 Female 172 lb 3/10/2011 Physician United States
Primary
Concomitant
Malaise Hospitalization 1/31/2011 63 Female 4/18/2011 Pharmacist France
Primary
Concomitant
Vitamin D Abnormal Other Serious 1/1/2008 47 Female 6/7/2011 Consumer Brazil
Primary
Concomitant
Completed Suicide Death 1/1/2008 23 Female 7/20/2011 Physician United States
Primary
Secondary
Neck Injury Other Serious 4/1/2009 41 Female 8/9/2011 Lawyer United States
Primary
Concomitant
Fatigue Other Serious 12/14/2011 38 Female 236 lb 12/16/2011 Pharmacist United States
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 43 Female 12/29/2011 Physician China
Primary
Concomitant
Death Death 1/1/2010 56 Female 12/26/2011 Physician United States
Primary
Secondary
Death Death 1/1/2010 33 Female 12/29/2011 Physician United States
Primary
Secondary
Palpitations Death 6/19/2004 52 Female 224 lb 12/21/2011 United States
Primary
Secondary
Concomitant
Death Death 33 Female 1/5/2012 Physician United States
Primary
Secondary
Death Death 56 Female 1/6/2012 Physician United States
Primary
Secondary
Dyspnoea Other Serious 1/1/1998 56 Male 229 lb 1/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 33 Female 1/11/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 56 Female 1/11/2012 Physician United States
Primary
Secondary
Abnormal Behaviour Other Serious 2/1/2007 35 Female 1/17/2012 Lawyer United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2010 33 Female 1/11/2012 Physician United States
Primary
Secondary
Anaemia Disability Female 1/18/2012 Physician United States
Primary
Concomitant
Arthralgia Other Serious Female 1/18/2012 Lawyer United States
Primary
Secondary
Concomitant
Poisoning Death 1/1/2010 56 Female 1/11/2012 Physician United States
Primary
Secondary
Arteriosclerosis Coronary Artery Death 6/19/2004 52 Female 224 lb 1/14/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Insomnia Other Serious 2/1/2007 35 Female 1/23/2012 Lawyer United States
Primary
Concomitant
Cardiac Arrest Death 1/1/2010 33 Female 1/13/2012 Physician United States
Primary
Secondary

Drug Data