Alprazolam combined with Paracetamol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Overweight Hospitalization 12/1/2005 69 Female 1/5/2006 France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 3/25/2005 Male 1/10/2006 Malaysia
Primary
Concomitant
Polymenorrhoea Other Serious 9/1/2005 40 Female 1/26/2006 France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 4/19/2005 48 Female 132 lb 2/8/2006
Primary
Secondary
Concomitant
Syncope Hospitalization 12/28/2005 65 Female 3/31/2006 Switzerland
Primary
Secondary
Concomitant
Nausea Other Serious 1/14/2006 41 Female 150 lb 4/4/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/1/2005 74 Male 176 lb 5/1/2006 Pharmacist France
Primary
Secondary
Concomitant
Vertigo Hospitalization 2/15/2006 61 Female 117 lb 5/16/2006 Physician Turkey
Primary
Concomitant
Neutropenia Required Intervention 5/26/2005 50 Female 2/7/2006 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 5/20/2006 26 Female 6/17/2006 Consumer Spain
Primary
Concomitant
Renal Failure Hospitalization 11/1/2005 74 Male 176 lb 7/5/2006 Pharmacist France
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/15/2006 53 Male 7/6/2006 Consumer United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 5/20/2006 26 Female 7/7/2006 Consumer Spain
Primary
Concomitant
Skin Exfoliation Hospitalization 1/27/2006 76 Female 209 lb 7/7/2006 Other Health Professional France
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 6/2/2006 Male 135 lb 7/7/2006 Consumer Canada
Primary
Secondary
Concomitant
Hypertension Hospitalization 7/24/2006 78 Female 8/24/2006 Spain
Primary
Concomitant
Renal Failure Acute Other Serious 6/15/2006 53 Male 9/15/2006 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 2/6/2006 61 Male 112 lb 9/25/2006 Physician France
Primary
Concomitant
Parkinsonian Gait Hospitalization 66 Male 9/26/2006 Physician Switzerland
Primary
Concomitant
Suicide Attempt Life Threatening Male 187 lb 9/26/2006 Other Health Professional Germany
Primary
Secondary
Pruritus 7/18/2006 66 Female 10/23/2006 United States
Primary
Concomitant
Drug Withdrawal Syndrome Hospitalization 11/18/2006 37 Male 2/28/2007 Other Health Professional France
Primary
Secondary
Osteopenia Hospitalization 8/4/2005 61 Male 3/1/2007 Physician Belgium
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 1/27/2007 Female 146 lb 4/23/2007 Physician Sweden
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 1/27/2007 Female 146 lb 5/17/2007 Physician Sweden
Primary
Concomitant
Syncope Other Serious 6/16/2006 53 Female 159 lb 6/21/2007 Physician Spain
Primary
Concomitant
Alveolitis Allergic Hospitalization 24 Female 9/18/2007 Other Health Professional France
Primary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Tibia Fracture Other Serious 9/22/2007 Female 150 lb 10/12/2007 Canada
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 7/18/2007 47 Female 126 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Life Threatening 7/18/2007 47 Female 11/6/2007 United States
Primary
Secondary
Concomitant
Jaundice Hospitalization 12/1/2005 39 Female 216 lb 11/9/2007 Other Health Professional France
Primary
Concomitant
Thrombocytopenia Life Threatening 8/24/2006 65 Female 220 lb 11/12/2007 Physician Belgium
Primary
Concomitant
Thrombocytopenia Life Threatening 8/24/2006 65 Female 220 lb 11/15/2007 Physician Belgium
Primary
Concomitant
Tumour Invasion Other Serious 5/1/2007 Female 11/16/2007 Belgium
Primary
Concomitant
Rales Hospitalization 4/21/2007 Female 188 lb 1/11/2008 Physician Denmark
Primary
Concomitant
Sodium Retention Life Threatening 5/1/2007 87 Female 1/15/2008 France
Primary
Secondary
Concomitant
Pruritus 8/28/2007 Female 1/15/2008 Physician United States
Primary
Concomitant
Sodium Retention Life Threatening 5/1/2007 87 Female 1/16/2008 Consumer France
Primary
Secondary
Concomitant
Myalgia Other Serious 12/1/2007 Female 159 lb 1/24/2008 France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 65 Female 1/25/2008 Consumer Chile
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 1/1/2005 Female 1/31/2008 Spain
Primary
Concomitant
Haematemesis Hospitalization 1/13/2008 Male 2/6/2008 Physician France
Primary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 1/1/2005 Female 2/7/2008 Spain
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 1/1/2005 Female 2/8/2008 Spain
Primary
Concomitant
Polymyalgia Rheumatica Other Serious 8/1/2007 Female 2/18/2008 Other Health Professional France
Primary
Secondary
Sudden Death Hospitalization 11/1/2007 74 Male 123 lb 3/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Other Serious 12/15/2007 Female 159 lb 4/7/2008 France
Primary
Secondary
Concomitant
Therapy Cessation Hospitalization 62 Female 110 lb 4/15/2008 Physician France
Primary
Concomitant
Polymyalgia Rheumatica Other Serious 8/1/2007 Female 4/24/2008 Other Health Professional France
Primary
Secondary
Biliary Cirrhosis Primary Hospitalization 1/1/2005 Female 4/25/2008 Spain
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 11/25/2008 Consumer United States
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 9/12/2008 Male 12/30/2008 Physician France
Primary
Concomitant
Retching Other Serious 11/12/2008 Female 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 3/2/2009 Consumer United States
Primary
Secondary
Concomitant
Polymyalgia Rheumatica Other Serious 8/1/2007 Female 3/20/2009 Other Health Professional France
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 2/2/2009 3/20/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/3/2009 45 Male 4/3/2009 Other Health Professional Portugal
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 10/6/2008 Male 4/27/2009 Physician France
Primary
Concomitant
Pneumonia Hospitalization 3/3/2009 45 Male 4/27/2009 Other Health Professional Portugal
Primary
Concomitant
Retching Other Serious 11/12/2008 Female 5/8/2009 Consumer United States
Primary
Secondary
Concomitant
Presyncope Hospitalization 5/1/2009 42 Female 341 lb 5/19/2009 Pharmacist Ireland
Primary
Concomitant
Graft Versus Host Disease Hospitalization 1/7/2008 55 5/27/2009 Physician Portugal
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 5/29/2009 Consumer United States
Primary
Secondary
Concomitant
Thyroid Cancer Hospitalization 3/1/2009 60 6/30/2009 Physician France
Primary
Concomitant
Pancytopenia Life Threatening 11/4/2008 75 Male 7/9/2009 Other Health Professional United States
Primary
Concomitant
Influenza Other Serious 7/2/2009 Female 148 lb 7/15/2009 Other Health Professional Chile
Primary
Secondary
Concomitant
Dehydration Death 9/23/2008 79 7/16/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/16/2009 Consumer United States
Primary
Secondary
Concomitant
Influenza Other Serious 7/2/2009 Female 148 lb 7/21/2009 Other Health Professional Chile
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 5/28/2009 Male 7/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Death 9/23/2008 79 7/31/2009 Other Health Professional Belgium
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/4/2009 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/22/2009 Female 131 lb 8/5/2009 Physician Argentina
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/7/2009 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 70 Male 8/28/2009
Primary
Secondary
Concomitant
Respiratory Rate Increased Other Serious 7/21/2009 51 Female 9/10/2009 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2009 66 Female 229 lb 10/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 70 Male 10/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 70 Male 10/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/22/2009 Female 131 lb 10/14/2009 Physician Argentina
Primary
Secondary
Concomitant
Septic Shock Life Threatening 7/1/2008 Female 146 lb 10/13/2009 Physician France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/22/2009 Female 131 lb 10/21/2009 Physician Argentina
Primary
Secondary
Concomitant
Streptococcal Infection Hospitalization 70 Male 10/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 70 Male 10/22/2009 Physician France
Primary
Secondary
Atrial Fibrillation Other Serious 70 Male 10/23/2009 Physician United States
Primary
Secondary
Atrial Fibrillation Other Serious 70 Male 11/5/2009 Physician United States
Primary
Secondary
Serotonin Syndrome Other Serious 10/2/2009 Female 11/9/2009 Pharmacist United States
Primary
Concomitant
Interacting
Pulmonary Embolism Hospitalization 11/12/2008 Female 11/10/2009 Consumer United States
Primary
Secondary
Concomitant
Headache Other Serious 50 Female 11/18/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Drug Abuse Other Serious 50 Female 11/16/2009 Spain
Primary
Secondary
Drug Abuse Other Serious 50 Female 11/23/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 11/24/2009 Consumer United States
Primary
Secondary
Concomitant
Headache Other Serious 50 Female 11/25/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Drug Abuse Other Serious 50 Female 12/4/2009 Spain
Primary
Secondary
Serotonin Syndrome Other Serious 10/2/2009 Female 123 lb 12/16/2009 Pharmacist United States
Primary
Concomitant
Interacting
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/16/2009 Physician India
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/23/2009 Physician India
Primary
Secondary
Concomitant
Oesophagectomy Hospitalization 12/1/2009 Female 12/22/2009 Physician United States
Primary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/28/2009 Physician India
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/29/2009 Physician India
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 1/6/2010 Physician India
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2008 44 Female 1/14/2010 Physician United States
Primary
Secondary
Pulmonary Oedema Life Threatening 3/4/2005 66 Male 158 lb 2/12/2010 Physician Belgium
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/4/2005 66 Male 159 lb 2/15/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Stress Cardiomyopathy Life Threatening 3/4/2005 66 Male 158 lb 2/18/2010 Physician Belgium
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 11/12/2009 Female 2/23/2010 Other Health Professional France
Primary
Secondary
Concomitant
Peripheral Ischaemia Other Serious 1/4/2010 Male 157 lb 3/2/2010 Consumer United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 3/1/2010 Female 3/5/2010 Belgium
Primary
Secondary
Concomitant
Overdose Other Serious 12/30/2009 55 Female 128 lb 3/10/2010 Pharmacist France
Primary
Concomitant
Pruritus Other Serious 8/1/2006 38 Female 3/11/2010 Physician Belgium
Primary
Concomitant
Peripheral Ischaemia Other Serious 1/4/2010 Male 157 lb 3/18/2010 Consumer United States
Primary
Secondary
Concomitant
Uterine Leiomyoma Other Serious 2/1/2009 Female 172 lb 3/26/2010 Brazil
Primary
Concomitant
Peripheral Ischaemia Life Threatening 1/4/2010 Male 157 lb 3/26/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 10/1/2009 53 Male 3/30/2010 Physician France
Primary
Concomitant
Interacting
Weight Decreased Other Serious 11/21/2009 74 Male 161 lb 4/1/2010 Physician India
Primary
Secondary
Concomitant
Visual Impairment Other Serious 10/1/2009 54 Male 4/2/2010 Physician France
Primary
Concomitant
Interacting
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 4/12/2010 Physician India
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/14/2009 78 Male 101 lb 4/15/2010 Physician France
Primary
Concomitant
Renal Failure Life Threatening 8/17/2006 54 Male 269 lb 4/23/2010 Physician Belgium
Primary
Concomitant
Cytolytic Hepatitis Hospitalization 3/23/2010 80 Female 4/30/2010 Other Health Professional France
Primary
Secondary
Concomitant
H1n1 Influenza Other Serious 7/2/2009 53 Female 148 lb 5/13/2010 Other Health Professional Chile
Primary
Secondary
Concomitant
Cerebral Haematoma Hospitalization 8/10/2006 61 Female 5/18/2010 Physician France
Primary
Concomitant
Overdose Other Serious 12/30/2009 55 Female 128 lb 5/19/2010 Pharmacist France
Primary
Concomitant
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 5/20/2010 Physician India
Primary
Secondary
Concomitant
Alveolitis Allergic Hospitalization 24 Female 5/25/2010 Other Health Professional France
Primary
Concomitant
Drug Toxicity Hospitalization 1/13/2010 24 Male 5/27/2010 Other Health Professional France
Primary
Secondary
Vaginal Haemorrhage Other Serious 2/1/2009 43 Female 172 lb 6/22/2010 Consumer Brazil
Primary
Concomitant
Overdose Hospitalization 1/13/2010 24 Male 6/22/2010 Other Health Professional France
Primary
Secondary
Hyperammonaemic Encephalopathy Required Intervention 51 Female 7/9/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 47 Male 7/9/2010 Physician United States
Primary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/19/2010 Physician Belgium
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/20/2010 Physician Belgium
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 7/16/2008 55 Female 146 lb 7/19/2010 Physician France
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 7/25/2007 50 Male 7/27/2010 Physician India
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/27/2010 Consumer United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 8/23/2010 Consumer United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 8/24/2010 Consumer United States
Primary
Secondary
Concomitant
Splenic Haemorrhage Other Serious 2/3/2009 60 Female 157 lb 9/20/2010 Physician Czech Republic
Primary
Concomitant
Lung Disorder Hospitalization 8/15/2010 80 Female 165 lb 9/20/2010 Physician Spain
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/1/2010 63 Female 10/7/2010 Physician Belgium
Primary
Secondary
Concomitant
Injection Site Nodule Other Serious 6/1/2010 42 Male 10/8/2010 Brazil
Primary
Concomitant
Dermatitis Exfoliative Other Serious 5/21/2010 59 Male 163 lb 10/20/2010 Physician Netherlands
Primary
Secondary
Concomitant
Mental Disorder Other Serious 45 Female 10/29/2010 Physician United States
Primary
Secondary
Respiratory Failure Hospitalization 64 Male 207 lb 11/5/2010 Physician Australia
Primary
Concomitant
Mucosal Inflammation Other Serious 10/15/2010 80 Female 132 lb 11/18/2010 Other Health Professional France
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 10/15/2010 80 Female 132 lb 12/1/2010 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 12/29/2008 64 Female 12/3/2010 Physician United States
Primary
Secondary
Concomitant
Overdose Hospitalization 39 Female 1/12/2011 Physician United Kingdom
Primary
Secondary

Drug Data