Alprazolam combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 12/18/2005 Female 148 lb 1/3/2006 Pharmacist Canada
Primary
Concomitant
Lactic Acidosis Required Intervention 11/14/2005 57 Male 286 lb 1/24/2006 Pharmacist United States
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 6/15/2005 66 Male 198 lb 2/9/2006 Poland
Primary
Concomitant
Interacting
Protein Urine Other Serious 1/1/2004 71 Female 190 lb 2/21/2006 Physician United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 8/1/2000 79 Male 154 lb 3/7/2006 Physician United States
Primary
Concomitant
Obesity Other Serious 2/1/2002 47 Female 287 lb 3/7/2006 Lawyer United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 2/1/2002 47 Female 287 lb 3/10/2006 Physician United States
Primary
Concomitant
Hypotension Required Intervention 11/4/2005 41 Female 2/9/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 7/28/2005 75 Female 138 lb 12/27/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 1/1/2001 64 Male 198 lb 3/30/2006 Physician United States
Primary
Concomitant
Ulcer Haemorrhage Other Serious 1/1/2002 40 Male 170 lb 4/25/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2003 80 Female 190 lb 4/27/2006 Physician United States
Primary
Concomitant
Thrombosis Other Serious 1/29/2002 59 Male 351 lb 5/3/2006 Lawyer United States
Primary
Concomitant
Ulcer Haemorrhage Other Serious 1/1/2002 40 Male 170 lb 5/11/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/1/2004 65 Female 231 lb 5/16/2006 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 1/29/2002 59 Male 351 lb 5/18/2006 Physician United States
Primary
Concomitant
Tooth Loss Other Serious 1/1/2003 80 Female 7/26/2006 Consumer United States
Primary
Concomitant
Tooth Loss Other Serious 1/1/2003 80 Female 170 lb 8/16/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 6/14/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 4/19/2003 69 Female 9/6/2006 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 79 Female 10/22/2007 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 79 Female 10/26/2007 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred 9/21/2007 Male 10/29/2007 Consumer United States
Primary
Concomitant
Sleep Disorder Other Serious 10/23/2007 84 Male 108 lb 11/20/2007 Physician United States
Primary
Secondary
Concomitant
Stress Other Serious 9/1/2007 Female 175 lb 12/7/2007 Consumer United States
Primary
Secondary
Concomitant
Injection Site Bruising 1/1/2007 Female 12/13/2007 Other Health Professional United States
Primary
Concomitant
Pruritus 8/19/2007 Male 261 lb 12/14/2007 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/21/2007 76 Female 12/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Overdose Death 56 Female 1/11/2008 Physician United States
Primary
Secondary
Completed Suicide Death 56 Female 1/11/2008 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious 8/1/2007 52 Female 4/18/2008 Pharmacist Netherlands
Primary
Concomitant
Weight Decreased Other Serious 8/1/2007 52 Female 5/2/2008 Pharmacist Netherlands
Primary
Concomitant
Thrombosis Other Serious 5/1/2008 Male 166 lb 6/12/2008 Pharmacist United States
Primary
Concomitant
Stomach Discomfort 2/1/2008 Female 170 lb 6/12/2008 Consumer United States
Primary
Concomitant
Mood Altered 3/1/2008 Male 180 lb 6/12/2008 United States
Primary
Concomitant
Dysgeusia 5/1/2008 Female 6/23/2008 Consumer United States
Primary
Concomitant
Weight Increased 62 Female 233 lb 6/26/2008 Consumer United States
Primary
Concomitant
Stent Placement Hospitalization 79 Male 6/25/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2008 Female 6/24/2008 Consumer United States
Primary
Concomitant
Dysgeusia 5/1/2008 Female 7/11/2008 Consumer United States
Primary
Concomitant
Dysgeusia 5/1/2008 82 Female 126 lb 8/1/2008 Physician United States
Primary
Concomitant
Urine Flow Decreased Other Serious 68 Male 8/4/2008 Consumer United States
Primary
Secondary
Concomitant
Transaminases Increased Life Threatening 6/19/2008 Female 8/5/2008 United States
Primary
Concomitant
Renal Impairment Hospitalization 71 Female 208 lb 9/12/2008 United States
Primary
Concomitant
Viral Infection Hospitalization 9/10/2008 Female 226 lb 9/29/2008 Physician Hungary
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2006 Female 9/30/2008 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1991 Male 188 lb 11/21/2008 United States
Primary
Secondary
Concomitant
Injection Site Irritation 11/18/2008 Male 178 lb 12/12/2008 Other Health Professional United States
Primary
Concomitant
Hypertension Hospitalization 12/1/2008 Female 12/23/2008 Physician United States
Primary
Secondary
Rash Other Serious 7/6/2008 Male 174 lb 12/24/2008 Other Health Professional United States
Primary
Concomitant
Metastasis Other Serious 68 Male 12/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Retching Other Serious 11/12/2008 Female 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 6/1/2008 Female 178 lb 1/7/2009 Physician United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 1/8/2009 United States
Primary
Concomitant
Ischaemic Stroke Death 6/1/2008 Female 178 lb 1/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 5/1/2008 1/23/2009 France
Primary
Concomitant
Interacting
Incorrect Route Of Drug Administration Death 8/1/2005 Male 193 lb 1/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Muscular Weakness Other Serious Female 2/25/2009 Consumer United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 67 Female 188 lb 2/26/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 3/2/2009 Consumer United States
Primary
Secondary
Concomitant
Skin Turgor Decreased Other Serious Female 143 lb 3/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Ocular Hyperaemia Other Serious Female 3/10/2009 Consumer United States
Primary
Concomitant
Ocular Hyperaemia Other Serious Female 3/11/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 1/1/1996 45 Male 4/2/2009 United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/1/2008 56 Female 4/6/2009 Physician United States
Primary
Concomitant
Retinal Detachment Other Serious 1/1/1998 Male 4/1/2009 Consumer United States
Primary
Concomitant
Overdose Death 56 Female 4/28/2009 Physician United States
Primary
Secondary
Overdose Death 56 Female 5/8/2009 Physician United States
Primary
Secondary
Retching Other Serious 11/12/2008 Female 5/8/2009 Consumer United States
Primary
Secondary
Concomitant
Vertigo Other Serious 66 Female 5/13/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1991 Male 188 lb 5/20/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 2/1/2008 Female 7/8/2009 Consumer United States
Primary
Concomitant
Death Death Female 103 lb 7/9/2009 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/29/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 62 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 72 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Ureteric Cancer Death 71 Male 7/22/2009 United States
Primary
Concomitant
Vomiting Hospitalization 65 Female 167 lb 7/22/2009 Lawyer United States
Primary
Concomitant
Papilloedema Hospitalization 7/9/2009 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 1/1/1985 Female 8/12/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/6/2007 72 Female 8/5/2009 United States
Primary
Concomitant
Papilloedema Hospitalization 7/9/2009 Female 8/14/2009 Physician Switzerland
Primary
Secondary
Concomitant
Ureteric Cancer Death 71 Male 8/4/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 54 Male 200 lb 8/20/2009 Consumer United States
Primary
Concomitant
Pruritus 8/30/2008 Male 8/21/2009 United States
Primary
Concomitant
Diarrhoea 9/24/2008 Female 81 lb 8/22/2009 Other Health Professional United States
Primary
Concomitant
Flushing 9/11/2008 Female 8/22/2009 United States
Primary
Concomitant
Flushing 11/1/2008 Female 8/22/2009 United States
Primary
Concomitant
Pruritus 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Muscle Spasms Female 8/22/2009 United States
Primary
Concomitant
Diarrhoea Male 196 lb 8/22/2009 Consumer United States
Primary
Concomitant
Nausea 5/6/2009 Female 8/22/2009 United States
Primary
Concomitant
Sepsis Death Female 103 lb 8/26/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2004 49 Male 265 lb 8/28/2009 United States
Primary
Concomitant
Qrs Axis Abnormal Death 6/1/2008 Female 178 lb 9/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Intentional Drug Misuse Death 9/4/2009 Physician United States
Primary
Secondary
Sensation Of Foreign Body 7/25/2009 Female 9/4/2009 Consumer
Primary
Concomitant
Completed Suicide Death 56 Female 9/8/2009 Physician United States
Primary
Secondary
Vomiting Hospitalization 7/21/2007 78 Female 9/11/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 9/15/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 6/2/2009 Male 300 lb 9/17/2009 United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 7/19/2009 Male 9/24/2009 Physician United States
Primary
Secondary
Concomitant
Tremor Required Intervention 7/21/2009 65 7/22/2009 United States
Primary
Secondary
Concomitant
Completed Suicide Death 56 Female 9/22/2009 United States
Primary
Secondary
Injury Death 69 Female 9/24/2009 Lawyer United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2009 66 Female 229 lb 10/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 7/19/2009 39 Male 10/1/2009 United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 7/19/2009 Male 10/9/2009 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 8/1/2009 51 Female 135 lb 10/12/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 48 Female 280 lb 10/15/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 59 Female 10/10/2009 United States
Primary
Concomitant
Stress At Work Other Serious 1/1/2009 51 Male 185 lb 10/8/2009 Consumer United States
Primary
Concomitant
Traumatic Haematoma Hospitalization 7/19/2009 39 Male 10/12/2009 Physician United States
Primary
Secondary
Concomitant
Thyroid Cyst Hospitalization 11/2/2007 78 Female 10/21/2009 United States
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 156 lb 10/27/2009 Lawyer United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 62 Male 187 lb 10/20/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/21/2007 79 Female 10/22/2009 United States
Primary
Concomitant
Condition Aggravated 9/1/2009 58 Female 10/29/2009 Consumer
Primary
Concomitant
Vision Blurred Other Serious 59 Female 10/26/2009 United States
Primary
Concomitant
Rash Other Serious 5/1/2009 61 Female 10/30/2009 Physician United States
Primary
Secondary
Concomitant
Drug Administered At Inappropriate Site 10/18/2009 Female 197 lb 11/2/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2009 48 Female 154 lb 10/22/2009 United States
Primary
Concomitant
Hypotension Other Serious 7/1/2007 77 Male 11/3/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/21/2007 79 Female 10/26/2009 Lawyer United States
Primary
Concomitant
Panic Attack Other Serious 62 Male 229 lb 10/26/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Female 10/26/2009 Lawyer United States
Primary
Concomitant
Stupor Hospitalization 8/10/2009 Male 10/30/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 59 Female 11/2/2009 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 11/10/2009 Consumer United States
Primary
Secondary
Concomitant
Peritonitis Bacterial Other Serious 10/9/2009 58 Female 11/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/21/2007 79 Female 11/4/2009 Consumer United States
Primary
Concomitant
Vertigo Hospitalization 62 Male 187 lb 11/4/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Female 11/9/2009 United States
Primary
Concomitant
Unemployment Other Serious 62 Male 229 lb 11/4/2009 United States
Primary
Concomitant
Weight Decreased Death 73 Female 11/5/2009 United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2009 69 Female 156 lb 11/16/2009 United States
Primary
Secondary
Concomitant
Overdose Death 56 Female 11/19/2009 Physician United States
Primary
Secondary
Renal Impairment 7/1/2009 Female 195 lb 11/24/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 12/24/2008 89 Female 11/25/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 56 Female 11/18/2009 United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 7/21/2007 79 Female 11/18/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Female 11/17/2009 United States
Primary
Concomitant
Vertigo Hospitalization 62 Male 187 lb 11/17/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 11/17/2009 United States
Primary
Concomitant
Hypoglycaemia 6/11/2009 74 Female 10/20/2009 Physician United States
Primary
Concomitant
Throat Tightness Hospitalization 1/1/2009 52 Female 330 lb 11/13/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Female 11/24/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 48 Female 280 lb 12/4/2009 United States
Primary
Concomitant

Drug Data