Alprazolam combined with Metoprolol Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pharmaceutical Product Complaint Other Serious 1/14/2006 41 Female 150 lb 3/22/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased 1/1/2005 68 Male 240 lb 1/20/2006 Consumer United States
Primary
Concomitant
Viral Pharyngitis Hospitalization 1/1/2001 50 Female 320 lb 4/10/2006 Physician United States
Primary
Concomitant
Nausea Other Serious 1/14/2006 41 Female 150 lb 4/4/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rash Other Serious 2/23/2006 55 Female 6/5/2006 Physician Hungary
Primary
Secondary
Concomitant
Urge Incontinence Hospitalization 6/19/2006 47 Female 112 lb 7/27/2006 Other Health Professional Germany
Primary
Concomitant
Dysgeusia 1/1/2006 56 Female 265 lb 7/12/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/1/2006 36 Male 210 lb 8/2/2006 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/2/2005 Female 185 lb 8/23/2006 Consumer United States
Primary
Concomitant
Peridiverticular Abscess Hospitalization 8/17/2003 53 Female 10/24/2006 Physician United States
Primary
Concomitant
Hypokalaemia Hospitalization 10/31/2006 Female 11/22/2006 Consumer United States
Primary
Concomitant
Oesophageal Ulcer Hospitalization 12/10/2005 82 Female 170 lb 11/22/2006 Consumer United States
Primary
Secondary
Concomitant
Stress Other Serious 1/1/2006 79 Female 78 lb 11/16/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Other Serious 9/8/2005 85 Male 198 lb 11/20/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/17/2006 57 Female 211 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Other Serious 70 Female 11/30/2006 Physician United States
Primary
Concomitant
Therapy Non-responder Other Serious 1/1/2006 61 Male 12/14/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/28/2005 76 Female 132 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Paradoxical Drug Reaction Hospitalization 1/24/2007 78 Female 112 lb 1/26/2007 Pharmacist United States
Primary
Concomitant
Overdose Death 30 Female 2/19/2007 Physician United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 70 Female 3/1/2007 Physician United States
Primary
Concomitant
Peritoneal Effusion Hospitalization 8/17/2003 53 Female 3/5/2007 Physician United States
Primary
Concomitant
Stomach Discomfort 2/21/2007 77 Female 3/8/2007 Pharmacist United States
Primary
Concomitant
Urine Output Decreased Hospitalization 2/26/2007 85 Male 204 lb 3/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Gout Hospitalization 2/7/2007 Female 250 lb 4/17/2007 Pharmacist United States
Primary
Concomitant
Vestibular Disorder Hospitalization 35 Female 4/2/2007 Physician United States
Primary
Secondary
Thoracic Vertebral Fracture Hospitalization 11/1/2004 Male 4/23/2007 Physician United States
Primary
Concomitant
Visual Disturbance Hospitalization 4/6/2007 71 Female 189 lb 4/18/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 85 Female 4/25/2007 Sweden
Primary
Concomitant
Pain In Extremity 10/1/2006 81 Male 1/23/2007 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 45 Male 12/13/2006 United States
Primary
Concomitant
Salivary Hypersecretion Hospitalization 1/1/2006 72 Female 108 lb 12/13/2006 Consumer United States
Primary
Concomitant
Thrombocythaemia Hospitalization 3/30/2007 Female 121 lb 6/11/2007 Physician Switzerland
Primary
Secondary
Concomitant
Vasospasm Hospitalization 84 Female 6/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vitreous Floaters Required Intervention 1/1/2005 66 Female 254 lb 6/13/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 9/10/2006 49 Female 6/13/2007 Physician United States
Primary
Concomitant
Sinus Bradycardia Life Threatening 84 Female 7/6/2007 Germany
Primary
Secondary
Concomitant
Performance Status Decreased Other Serious 7/1/2007 Female 125 lb 7/23/2007 Consumer United States
Primary
Concomitant
Viral Infection Hospitalization 3/1/2007 66 Male 7/2/2007 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 11/1/2006 Female 129 lb 8/13/2007 Consumer United States
Primary
Concomitant
Vascular Graft Other Serious 1/1/2005 Female 115 lb 8/31/2007 Consumer United States
Primary
Concomitant
Performance Status Decreased Other Serious 7/1/2007 Female 125 lb 9/7/2007 Physician United States
Primary
Concomitant
Hypotension Other Serious 11/1/2006 81 Male 7/13/2007 Other Health Professional United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 6/28/2005 76 Female 132 lb 9/7/2007 United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 7/18/2007 47 Female 126 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Life Threatening 7/18/2007 47 Female 11/6/2007 United States
Primary
Secondary
Concomitant
Pruritus 8/19/2007 Male 261 lb 12/14/2007 United States
Primary
Concomitant
Vomiting Hospitalization 10/4/2007 Female 12/14/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/4/2007 Female 1/11/2008 Physician United States
Primary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 7/1/2004 77 Female 127 lb 11/29/2007 Consumer United States
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 5/21/2007 76 Female 150 lb 12/3/2007 Consumer United States
Primary
Concomitant
Convulsion Other Serious 1/1/2007 60 Female 1/17/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 1/17/2008 70 Male 181 lb 2/26/2008 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious Female 4/10/2008 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious Female 4/10/2008 Physician United States
Primary
Concomitant
Pyrexia Life Threatening 3/11/2008 60 Female 190 lb 4/14/2008 Physician Switzerland
Primary
Secondary
Concomitant
Wrong Drug Administered Hospitalization 4/23/2008 79 Female 108 lb 5/15/2008 Pharmacist United States
Primary
Concomitant
Pyrexia Life Threatening 3/11/2008 59 Female 190 lb 5/23/2008 Physician Switzerland
Primary
Secondary
Concomitant
Macular Degeneration Other Serious Female 6/9/2008 Consumer United States
Primary
Concomitant
Precancerous Skin Lesion Female 6/13/2008 Consumer United States
Primary
Concomitant
Presyncope Hospitalization 63 Female 6/16/2008 Turkey
Primary
Secondary
Concomitant
Stomatitis Other Serious 3/15/2008 66 Female 6/30/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 3/24/2008 Female 176 lb 7/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2008 Female 170 lb 7/2/2008 Consumer United States
Primary
Concomitant
Interacting
Vomiting Hospitalization 3/24/2008 Female 176 lb 7/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Palpitations 1/1/2006 Female 167 lb 8/27/2008 Consumer United States
Primary
Concomitant
Flushing 10/15/2007 Female 8/27/2008 Consumer United States
Primary
Concomitant
Pharyngeal Oedema 12/1/2007 Female 181 lb 8/27/2008 Consumer United States
Primary
Concomitant
Sensory Disturbance 6/17/2008 Male 8/29/2008 United States
Primary
Concomitant
Pruritus Generalised 7/1/2008 Male 8/29/2008 United States
Primary
Concomitant
Injection Site Pain 1/23/2007 Female 280 lb 9/13/2008 United States
Primary
Concomitant
Platelet Count Decreased Other Serious 10/13/2008 53 Male 170 lb 10/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sensory Disturbance 6/17/2008 Male 11/26/2008 United States
Primary
Concomitant
Oedema Peripheral 8/25/2008 Female 11/26/2008 Consumer United States
Primary
Concomitant
Pain 11/1/2008 Male 11/26/2008 United States
Primary
Concomitant
Medication Residue 1/1/2005 Male 240 lb 12/4/2008 Physician United States
Primary
Concomitant
Myalgia Hospitalization 5/28/2008 Female 147 lb 12/4/2008 Physician United States
Primary
Secondary
Concomitant
Photosensitivity Reaction 1/1/2005 Male 165 lb 12/4/2008 Consumer United States
Primary
Concomitant
Procedural Complication 8/30/2008 Male 300 lb 12/12/2008 Consumer United States
Primary
Concomitant
Drug Administration Error 74 Male 12/10/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/26/2009 Male 205 lb 2/5/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased 9/1/2008 Female 160 lb 4/2/2009 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 4/22/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2008 44 Male 192 lb 5/7/2009 Consumer United States
Primary
Concomitant
Treatment Noncompliance 5/21/2009 Female 230 lb 5/28/2009 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2008 Male 230 lb 5/28/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 5/29/2009 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2008 Male 230 lb 6/3/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased 2/1/2009 Female 6/12/2009 Physician United States
Primary
Concomitant
Angina Unstable Hospitalization 1/13/2009 Male 292 lb 6/12/2009 Consumer United States
Primary
Concomitant
Product Substitution Issue Other Serious 2/19/2009 73 Female 6/12/2009 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 49 Female 6/10/2009 United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2008 Male 230 lb 6/24/2009 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 6/25/2006 Female 7/8/2009 Other Health Professional United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2008 Male 230 lb 7/9/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/20/2002 41 Female 275 lb 7/10/2009 United States
Primary
Concomitant
Wound Secretion Hospitalization 62 Female 7/12/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/16/2009 Consumer United States
Primary
Secondary
Concomitant
Surgery Death 73 Female 7/13/2009 United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2008 Male 230 lb 7/17/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 68 Female 7/15/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 62 Female 7/19/2009 Lawyer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 6/1/2008 Female 178 lb 7/22/2009 Physician United States
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 11/1/2005 32 Female 133 lb 7/24/2009 United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2008 Male 230 lb 7/29/2009 Other Health Professional United States
Primary
Concomitant
Rash 69 Male 8/6/2009 Consumer
Primary
Concomitant
Weight Decreased Other Serious 7/1/2009 48 Female 154 lb 7/30/2009 Consumer United States
Primary
Concomitant
Weight Decreased Death 75 Female 7/31/2009 Lawyer United States
Primary
Concomitant
Ocular Hyperaemia Other Serious 77 Female 8/13/2009 Consumer United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2008 Male 230 lb 8/14/2009 Other Health Professional United States
Primary
Concomitant
Skin Discomfort 5/9/2002 Male 163 lb 8/21/2009 Consumer United States
Primary
Concomitant
Tinnitus 8/1/2008 Male 190 lb 8/21/2009 Consumer United States
Primary
Concomitant
Nausea 10/1/2008 Female 200 lb 8/22/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 6/13/2007 Female 222 lb 9/11/2009 Consumer United States
Primary
Concomitant
Mental Disorder Hospitalization 7/15/2009 76 Female 9/9/2009 Other Health Professional Netherlands
Primary
Concomitant
Ventricular Failure Hospitalization 49 Female 9/14/2009 United States
Primary
Concomitant
Unevaluable Event Death 6/21/2008 78 Male 9/15/2009 United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2008 Female 207 lb 9/29/2009 Consumer Brazil
Primary
Concomitant
Completed Suicide Death 56 Female 9/22/2009 Physician United States
Primary
Secondary
Ischaemic Stroke Death 6/1/2008 Female 178 lb 9/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/17/2008 70 Male 181 lb 9/25/2009 Physician United States
Primary
Concomitant
Self-medication Death 67 Female 1/17/2010 Physician United States
Primary
Secondary
Renal Failure Chronic Other Serious 11/1/2007 60 Male 3/18/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Other Serious 11/1/2007 60 Male 6/15/2010 Other Health Professional United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2008 54 Female 179 lb 6/16/2010 Lawyer United States
Primary
Concomitant
Social Avoidant Behaviour Other Serious 4/1/2010 67 Female 130 lb 7/7/2010 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective 3/1/2010 64 Male 199 lb 6/21/2010 Consumer United States
Primary
Concomitant
Syncope Hospitalization 5/6/2010 61 Female 146 lb 7/22/2010 Physician United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/27/2010 Consumer United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 5/28/2008 60 Female 147 lb 7/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 5/6/2010 61 Female 146 lb 7/29/2010 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 7/1/2008 54 Female 179 lb 8/12/2010 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 11/1/2007 60 Male 9/30/2010 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 5/6/2010 61 Female 146 lb 9/29/2010 Physician United States
Primary
Secondary
Concomitant
Treatment Failure Hospitalization 2/1/2010 67 Female 174 lb 11/9/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2009 56 Female 106 lb 11/25/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 65 Male 188 lb 11/26/2010 United States
Primary
Secondary
Concomitant
Vitamin D Decreased Other Serious 1/1/1998 58 Male 165 lb 11/24/2010 United States
Primary
Secondary
Vomiting Other Serious 1/1/2007 53 Female 146 lb 12/2/2010 Other Health Professional United States
Primary
Concomitant
Septic Shock Hospitalization 2/1/2010 67 Female 174 lb 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Palpitations 5/1/2010 68 Female 12/14/2010 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/15/2010 71 Female 145 lb 12/2/2010 Physician United States
Primary
Concomitant
Ejection Fraction Decreased Other Serious 5/1/2010 49 Male 165 lb 12/28/2010 Physician Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/15/2010 71 Female 145 lb 12/13/2010 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 11/10/2010 83 Male 170 lb 1/11/2011 Physician United States
Primary
Secondary
Concomitant
Headache Other Serious 7/1/2008 54 Female 179 lb 2/3/2011 Physician United States
Primary
Concomitant
Respiratory Arrest Death 38 Female 1/26/2011 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 38 Female 1/20/2011 Physician United States
Primary
Secondary

Drug Data