Alprazolam combined with Methadone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Overdose Life Threatening 7/21/2005 48 Male 227 lb 8/29/2005 Pharmacist United States
Primary
Secondary
Hypotension Required Intervention 11/4/2005 41 Female 2/9/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 9/14/2001 Female 253 lb 4/26/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 33 11/9/2006 United States
Primary
Secondary
Treatment Noncompliance Death 44 Female 1/3/2007 Physician United States
Primary
Secondary
Suicidal Ideation Death 44 Female 1/3/2007 Physician United States
Primary
Secondary
Respiratory Arrest Other Serious 47 Male 7/11/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 17 Male 12/23/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 41 Female 12/23/2008 Physician United States
Primary
Secondary
Drug Abuse Death 1/1/2007 62 Male 12/23/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 22 Male 12/24/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 37 Male 12/29/2008 Physician United States
Primary
Secondary
Transaminases Increased Hospitalization 5/1/2008 3/23/2009 Other Health Professional France
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 10/10/2007 Male 190 lb 3/27/2009 Consumer
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 10/10/2007 Male 190 lb 3/30/2009 Consumer
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Death 1/1/1996 45 Male 4/2/2009 United States
Primary
Concomitant
Death Death 4/6/2009 Physician
Primary
Secondary
Therapeutic Agent Toxicity Other Serious Male 190 lb 4/14/2009 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious Male 190 lb 4/16/2009 Consumer United States
Primary
Secondary
Concomitant
Withdrawal Syndrome 1/1/2008 41 Female 155 lb 5/19/2009 Consumer United States
Primary
Concomitant
Anxiety Hospitalization 5/11/2009 62 Male 162 lb 5/20/2009 Physician United States
Primary
Concomitant
Dizziness Hospitalization 5/11/2009 62 Male 162 lb 5/26/2009 Physician United States
Primary
Concomitant
Drug Toxicity Other Serious 28 Male 6/12/2009 Physician United States
Primary
Secondary
Wrong Technique In Drug Usage Process Other Serious 5/6/2005 Female 164 lb 6/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Death 1/1/2007 40 Male 6/12/2009 Physician United States
Primary
Secondary
Staphylococcal Infection Hospitalization 5/28/2009 66 Male 143 lb 6/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 28 Male 6/26/2009 Physician United States
Primary
Secondary
Pulmonary Congestion Death 28 Male 181 lb 6/29/2009 Physician United States
Primary
Secondary
Wrong Technique In Drug Usage Process Other Serious 5/6/2005 Female 164 lb 7/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 5/6/2005 Female 164 lb 7/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 5/6/2005 Female 164 lb 7/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Generalised 6/9/2009 52 Female 154 lb 7/8/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/2/2002 52 Male 7/10/2009 United States
Primary
Concomitant
Platelet Count Decreased Other Serious Male 135 lb 8/6/2009 Consumer United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Accidental Death 15 Male 12/11/2009 Physician United States
Primary
Secondary
Drug Toxicity Death 15 Male 12/14/2009 Consumer United States
Primary
Secondary
Drug Ineffective 69 Male 12/9/2009 Consumer United States
Primary
Concomitant
Intentional Drug Misuse Death 16 Male 12/29/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Hospitalization 24 Female 1/8/2010 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 46 Female 1/8/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 51 Male 1/8/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 53 Female 1/8/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 22 Male 1/12/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 23 Male 1/12/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 29 Male 1/12/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 24 Female 1/12/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 26 Male 1/12/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 27 Male 1/12/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 30 Female 1/12/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 23 Female 1/12/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 23 Male 1/12/2010 Physician United States
Primary
Secondary
Death Death 1/1/2008 30 Female 1/14/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 30 Male 1/14/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 44 Female 1/14/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 39 Male 1/14/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 20 Female 1/14/2010 Physician United States
Primary
Secondary
Completed Suicide Death 46 Female 1/17/2010 Physician United States
Primary
Secondary
Completed Suicide Death 26 Male 1/17/2010 Physician United States
Primary
Secondary
Drug Toxicity Other Serious 46 Female 1/25/2010 Physician United States
Primary
Secondary
Completed Suicide Death 26 Male 1/20/2010 United States
Primary
Secondary
Intentional Drug Misuse Death 50 Female 1/26/2010 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 23 Male 2/2/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 24 Female 2/2/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 30 Female 2/2/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 30 Female 2/2/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 29 Male 2/2/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 27 Male 2/2/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 39 Male 2/2/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 46 Female 2/2/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 26 Male 2/2/2010 Physician United States
Primary
Secondary
Unresponsive To Stimuli Death 1/1/2008 12 Male 2/2/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2008 22 Male 2/2/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 44 Female 2/2/2010 Physician United States
Primary
Secondary
Completed Suicide Death 26 Male 2/22/2010 United States
Primary
Secondary
Wrong Technique In Drug Usage Process Death 5/25/2006 50 Male 228 lb 3/1/2010 Physician United States
Primary
Secondary
Drug Abuse Death 50 Female 2/26/2010 Other Health Professional United States
Primary
Secondary
Wound Drainage Other Serious 10/29/2001 Female 144 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 26 Male 3/4/2010 Other Health Professional United States
Primary
Secondary
Drug Abuse Death 23 Male 2/26/2010 Physician Denmark
Primary
Secondary
Wound Drainage Other Serious 10/29/2001 Female 144 lb 3/19/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 1/1/2008 30 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2008 46 Female 3/24/2010 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2008 50 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Withdrawal Syndrome 3/31/2009 49 Male 147 lb 3/30/2010 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious Male 4/28/2010 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Death 7/2/2007 Male 5/18/2010 Other Health Professional United States
Primary
Secondary
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 5/20/2010 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 1/1/1996 44 Male 5/24/2010 Other Health Professional United States
Primary
Concomitant
Multiple Drug Overdose Death 12/21/2009 21 Female 130 lb 5/27/2010 Consumer United States
Primary
Secondary
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 5/27/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 41 Female 185 lb 5/28/2010 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/21/2010 50 Male 200 lb 6/1/2010 Consumer United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 61 Male 256 lb 6/1/2010 Physician United States
Primary
Concomitant
Drug Toxicity Death 21 Female 6/3/2010 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 32 Male 6/3/2010 Physician United States
Primary
Secondary
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/10/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/14/2010 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 7/2/2007 21 Male 150 lb 6/21/2010 Physician United States
Primary
Secondary
Precancerous Skin Lesion Other Serious 6/1/2010 74 Female 6/22/2010 Consumer
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/23/2010 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Death 36 Male 6/24/2010
Primary
Secondary
Drug Toxicity Death 1/1/2010 47 Male 6/25/2010 Physician United States
Primary
Secondary
Drug Ineffective 10/5/2007 43 Female 135 lb 6/29/2010 Consumer United States
Primary
Concomitant
Panic Reaction 5/14/2008 38 Female 190 lb 6/29/2010 Consumer United States
Primary
Concomitant
Substance Abuse Other Serious 3/1/2010 49 Male 7/1/2010 Consumer United States
Primary
Secondary
Substance Abuse Other Serious 3/1/2010 25 Female 7/1/2010 Consumer United States
Primary
Secondary
Substance Abuse Other Serious 3/16/2010 49 Male 7/7/2010 Consumer United States
Primary
Secondary
Substance Abuse Other Serious 3/16/2010 25 Female 7/7/2010 Consumer United States
Primary
Secondary
Weight Increased 2/1/2008 44 Female 142 lb 7/7/2010 Consumer United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2000 34 Male 7/7/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Blood Glucose Increased Male 195 lb 7/9/2010 Consumer United States
Primary
Concomitant
Somnolence Female 234 lb 8/3/2010 Consumer United States
Primary
Secondary
Concomitant
Interacting
Drug Toxicity Death 25 Female 8/4/2010 Physician United States
Primary
Secondary
Drug Toxicity Death 1/1/2010 47 Male 8/5/2010 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 49 Male 8/8/2010 Physician United States
Primary
Secondary
Drug Toxicity Death 24 Male 8/19/2010 Physician United States
Primary
Secondary
Somnolence Other Serious 36 Male 8/12/2010 Australia
Primary
Secondary
Oedema Peripheral 7/3/2010 Female 8/24/2010 Consumer
Primary
Concomitant
Drug Toxicity Other Serious 3/16/2010 49 Male 8/27/2010 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death Female 145 lb 8/27/2010 Physician United States
Primary
Secondary
Pulmonary Congestion Other Serious 25 Female 192 lb 8/27/2010 Physician United States
Primary
Secondary
Overdose Death Male 8/27/2010 Physician United States
Primary
Interacting
Wound Dehiscence Other Serious 1/1/2000 34 Male 8/30/2010 United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 8/1/2010 61 Female 8/26/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2010 58 Male 185 lb 8/31/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 49 Male 174 lb 9/3/2010 United States
Primary
Secondary
Fatigue 2/13/2009 45 Female 177 lb 9/9/2010 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 61 Male 256 lb 9/16/2010 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 8/26/2004 54 Female 100 lb 9/20/2010 United States
Primary
Concomitant
Substance Abuse Other Serious Male 196 lb 9/22/2010 Consumer United States
Primary
Secondary
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 9/30/2010 United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 10/1/2009 66 Male 10/4/2010 Consumer United States
Primary
Concomitant
Hypertension Other Serious 8/1/2010 50 Female 175 lb 10/6/2010 United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2002 73 Female 144 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2002 73 Female 144 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 1/1/2007 41 Male 10/8/2010 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 8/26/2010 60 Male 264 lb 10/7/2010 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2002 73 Female 144 lb 10/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Precancerous Skin Lesion Other Serious 1/1/2004 74 Female 10/15/2010 Consumer
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2000 34 Male 10/19/2010 United States
Primary
Secondary
Concomitant
Drug Toxicity Death 26 Male 10/19/2010 Pharmacist United States
Primary
Secondary
Sepsis Other Serious 12/23/2009 55 Female 210 lb 10/18/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/22/2002 64 Male 185 lb 10/26/2010 United States
Primary
Concomitant
Presyncope Hospitalization Female 160 lb 10/28/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/21/2010 50 Male 200 lb 11/2/2010 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious Male 264 lb 11/10/2010 Physician United States
Primary
Concomitant
Staphylococcal Sepsis Other Serious 12/9/2009 66 Male 12/6/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 5/22/2002 64 Male 185 lb 12/14/2010 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 61 Male 256 lb 6/1/2010 Physician United States
Primary
Concomitant

Drug Data