Alprazolam combined with Methadone Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Other Serious 8/1/2005 40 Male 150 lb 2/15/2006 United States
Primary
Secondary
Concomitant
Stridor Disability 2/24/2006 45 Female 5/8/2006 United States
Primary
Concomitant
Respiratory Arrest Death 20 5/23/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 32 5/23/2006 Physician United States
Primary
Secondary
Palpitations Other Serious 7/2/2006 77 Female 7/20/2006 United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Death 43 Female 9/14/2006 Physician United States
Primary
Secondary
Ventricular Fibrillation Hospitalization 30 Female 9/15/2006 Physician United States
Primary
Secondary
Melaena Hospitalization 9/13/2006 56 Male 154 lb 9/21/2006 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Death 43 Female 9/22/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 43 10/12/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 43 10/12/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 18 11/9/2006 United States
Primary
Secondary
Respiratory Arrest Death 32 NotSpecified 11/17/2006 Physician United States
Primary
Secondary
Substance Abuse Other Serious 5/1/2006 23 Male 143 lb 12/1/2006 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 24 11/22/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 48 Unknown 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 44 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 29 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 29 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 34 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 33 Unknown 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 45 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 18 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 33 11/21/2006 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2005 45 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 31 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 28 Unknown 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 18 Unknown 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 33 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 27 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 44 11/3/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 40 NotSpecified 11/21/2006 Physician United States
Primary
Secondary
Drug Toxicity Death 1/1/2005 31 Unknown 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 32 Unknown 11/21/2006 Physician United States
Primary
Secondary
Tremor Life Threatening 50 Female 11/30/2006 Physician United States
Primary
Secondary
Concomitant
Overdose Hospitalization 12/28/2005 32 Male 10/3/2006 Pharmacist United States
Primary
Secondary
Tonic Clonic Movements Required Intervention 7/26/2006 Male 7/31/2006 Pharmacist United States
Primary
Concomitant
Substance Abuse Death 2/2/2006 48 Male 2/5/2007 Consumer United States
Primary
Secondary
Drug Toxicity Death 2/15/2007
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2005 32 Unknown 2/8/2007 Physician United States
Primary
Secondary
Drug Toxicity Death 2/21/2007 Belgium
Primary
Secondary
Pharmaceutical Product Complaint 12/1/2006 46 Male 218 lb 2/23/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 12/29/2006 46 Male 218 lb 3/2/2007 Other Health Professional United States
Primary
Concomitant
Drug Toxicity Death 3/12/2007
Primary
Secondary
Blood Glucose Increased 10/1/2006 79 Male 12/5/2006 United States
Primary
Concomitant
Drug Toxicity Death 3/16/2007 Belgium
Primary
Secondary
Middle Insomnia Other Serious 1/1/2007 35 Male 190 lb 3/14/2007 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 12/6/2006 46 Male 218 lb 3/21/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 12/6/2006 46 Male 218 lb 3/29/2007 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization 3/25/2007 58 Male 179 lb 3/29/2007 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 12/6/2006 46 Male 218 lb 4/17/2007 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 52 Female 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 52 Female 5/4/2007
Primary
Concomitant
Multiple Myeloma Death 4/18/2007 71 Female 4/27/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/30/2007 74 Female 115 lb 5/30/2007 Consumer United States
Primary
Concomitant
Wheezing Other Serious 1/1/2007 Female 170 lb 6/8/2007 Consumer United States
Primary
Concomitant
Urinary Incontinence Other Serious 6/14/2006 52 Female 160 lb 4/4/2007 United States
Primary
Concomitant
Multiple Myeloma Death 4/18/2007 71 Female 6/11/2007 Physician United States
Primary
Secondary
Concomitant
Substance Abuse Other Serious 1/1/2006 28 Male 5/24/2007 Consumer United States
Primary
Secondary
Multiple Myeloma Death 71 Female 6/25/2007 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 127 lb 7/20/2007 Consumer United States
Primary
Concomitant
Negative Thoughts 1/24/2007 43 Female 8/30/2007 Consumer United States
Primary
Concomitant
Bradycardia Other Serious 9/25/2007 49 Female 10/5/2007 Physician United States
Primary
Concomitant
Respiratory Arrest Other Serious 32 10/29/2007 Physician United States
Primary
Secondary
Obsessive-compulsive Disorder 4/1/2006 Female 12/27/2007 Consumer United States
Primary
Concomitant
Multiple Drug Overdose Accidental Death 2/12/2007 43 Female 244 lb 10/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Accidental Other Serious 12/21/2003 40 Female 10/31/2007 Physician United States
Primary
Secondary
Concomitant
Intentional Drug Misuse Hospitalization 58 Female 1/15/2008 Physician United States
Primary
Secondary
Drug Toxicity Death 26 Male 1/15/2008 Physician United States
Primary
Secondary
Encephalopathy Death 1/1/2006 24 Male 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 26 Male 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 41 Female 1/18/2008 United States
Primary
Secondary
Intentional Drug Misuse Death 1/1/2006 58 Female 1/18/2008 United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2006 47 Male 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 32 Male 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 18 Male 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 18 Male 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 30 Male 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 26 Male 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 41 Male 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Life Threatening 1/1/2006 23 Male 1/18/2008 United States
Primary
Secondary
Tachycardia Other Serious 1/1/2002 52 Female 150 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Arrest Death 26 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 47 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 18 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 18 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 41 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 23 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 26 Male 1/22/2008 Physician United States
Primary
Secondary
Poisoning Hospitalization 24 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 41 Female 1/22/2008 Physician United States
Primary
Secondary
Drug Abuse Death 32 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 30 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 26 Male 1/22/2008 Physician United States
Primary
Secondary
Poisoning Death 58 Female 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 47 Male 1/22/2008 Physician United States
Primary
Secondary
Drug Abuse Death 1/29/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 23 Male 1/28/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 18 Male 1/28/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 41 Female 1/28/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 47 Male 1/28/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 18 Male 1/28/2008 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2006 26 Male 1/28/2008 Physician United States
Primary
Secondary
Death Death 1/1/2006 26 Male 1/28/2008 Physician United States
Primary
Secondary
Weight Decreased Other Serious Male 311 lb 2/5/2008 Consumer United States
Primary
Concomitant
Intentional Drug Misuse Death 58 Female 2/5/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 47 Male 2/5/2008 Physician United States
Primary
Secondary
Death Death 1/1/2006 26 Male 2/11/2008 United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 18 Male 2/13/2008 United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 26 Male 2/13/2008 Physician United States
Primary
Secondary
Urinary Tract Infection Other Serious 10/18/2007 46 Female 176 lb 2/12/2008 Other Health Professional United States
Primary
Concomitant
Cardio-respiratory Arrest Death 1/1/2006 18 Male 2/13/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 23 Male 2/13/2008 Physician United States
Primary
Secondary
Death Death 1/1/2006 58 Female 2/13/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 41 Female 2/13/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 26 Male 2/13/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 30 Male 2/13/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 32 Male 2/13/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 47 Male 2/13/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 41 Male 2/12/2008 Physician United States
Primary
Secondary
Sedation Other Serious 40 Female 2/29/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2007 Male 311 lb 4/11/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/18/2007 46 Female 176 lb 4/23/2008 Other Health Professional United States
Primary
Concomitant
Skin Ulcer Hospitalization 12/31/2007 55 Female 5/2/2008 Consumer United States
Primary
Concomitant
Respiratory Arrest Life Threatening 23 Male 5/19/2008 Physician United States
Primary
Secondary
Therapeutic Response Decreased Hospitalization 1/1/2004 Female 150 lb 6/12/2008 Physician United States
Primary
Concomitant
Pain In Jaw Hospitalization 3/17/2008 45 Male 160 lb 6/12/2008 Consumer United States
Primary
Secondary
Concomitant
Death Death 40 6/19/2008 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 65 7/11/2008 Other Health Professional United States
Primary
Secondary
Homicidal Ideation Other Serious 6/1/2008 Female 146 lb 9/8/2008 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/18/2007 46 Female 176 lb 9/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 12/31/2007 55 Female 9/29/2008 United States
Primary
Concomitant
Tremor Other Serious 9/15/2008 Male 165 lb 10/4/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 7/16/2008 44 Male 10/15/2008 Spain
Primary
Concomitant
Skin Ulcer Other Serious 12/31/2007 55 Female 10/20/2008 United States
Primary
Concomitant
Withdrawal Syndrome Death 2/1/2006 Male 406 lb 11/4/2008 Consumer
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/16/2008 44 Male 11/11/2008 Spain
Primary
Concomitant
Intentional Drug Misuse Death 58 Female 11/3/2008 Physician United States
Primary
Secondary
Concomitant
Joint Stiffness 1/1/2007 Male 252 lb 12/8/2008 Physician United States
Primary
Concomitant
Extrapyramidal Disorder Other Serious 82 Female 12/19/2008 Physician United States
Primary
Concomitant
Withdrawal Syndrome Death 2/1/2006 Male 406 lb 12/19/2008 Consumer
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2007 28 Male 12/24/2008 Physician United States
Primary
Secondary
Death Death 1/1/2007 47 Female 12/24/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 29 Male 12/24/2008 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2007 32 Male 12/24/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 51 Male 12/24/2008 Physician United States
Primary
Secondary
Splenomegaly 1/1/1995 Female 1/7/2009 Physician United States
Primary
Secondary
Concomitant
Overdose Other Serious 22 Female 1/9/2009 Other Health Professional United States
Primary
Secondary
Multiple Drug Overdose Death 10/24/2004 44 Female 119 lb 1/9/2009 Physician United States
Primary
Secondary
Intentional Drug Misuse Death 1/1/2007 17 Male 1/6/2009 United States
Primary
Secondary

Drug Data