Alprazolam combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lactic Acidosis Required Intervention 11/14/2005 57 Male 286 lb 1/24/2006 Pharmacist United States
Primary
Concomitant
Pericardial Effusion Other Serious 1/1/2003 75 Female 201 lb 2/23/2006 Physician United States
Primary
Concomitant
Stomach Discomfort 11/1/2005 47 Male 3/7/2006 Consumer United States
Primary
Concomitant
Nervous System Disorder 54 3/7/2006 Consumer United States
Primary
Concomitant
Stomach Discomfort 11/1/2005 47 Male 3/7/2006 Consumer United States
Primary
Concomitant
Nervous System Disorder 54 3/7/2006 Consumer United States
Primary
Concomitant
Cholelithiasis Hospitalization 1/10/2006 32 Female 3/15/2006 Consumer United States
Primary
Concomitant
Wound Haemorrhage Hospitalization 2/4/2000 70 Female 231 lb 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 6/12/2004 57 Female 265 lb 3/29/2006 Other Health Professional Netherlands
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 6/1/2000 66 Female 157 lb 3/31/2006 Physician United States
Primary
Concomitant
Shoulder Pain Hospitalization 1/1/2002 64 Female 234 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Shoulder Pain Hospitalization 1/1/2002 64 Female 234 lb 4/10/2006 Physician United States
Primary
Concomitant
Medication Error 10/8/2005 64 Female 285 lb 1/20/2006 Other Health Professional United States
Primary
Concomitant
Retinal Detachment Other Serious 1/1/2001 61 Female 4/7/2006 Brazil
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/1998 58 Female 4/7/2006 Brazil
Primary
Concomitant
Cerebral Ischaemia Other Serious 1/1/2002 62 Female 4/7/2006 Brazil
Primary
Concomitant
Pharmaceutical Product Complaint 4/3/2006 48 Female 4/11/2006 Pharmacist United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2003 75 Male 183 lb 4/24/2006 Physician United States
Primary
Concomitant
Cerebral Ischaemia Other Serious 1/1/2002 62 Female 4/19/2006 Brazil
Primary
Concomitant
Retinal Detachment Other Serious 1/1/2001 61 Female 4/21/2006 Brazil
Primary
Concomitant
Stridor Disability 2/24/2006 45 Female 5/8/2006 United States
Primary
Concomitant
Thrombin Time Prolonged Life Threatening 9/7/2005 63 Male 175 lb 5/9/2006 Physician Hungary
Primary
Secondary
Concomitant
Stress At Work 3/11/2006 57 Male 183 lb 4/17/2006 Consumer United States
Primary
Concomitant
Skin Exfoliation Hospitalization 1/27/2006 76 Female 209 lb 7/7/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pain In Extremity 3/7/2006 39 Male 4/17/2006 Consumer United States
Primary
Concomitant
Paraesthesia 8/17/2005 67 Male 7/21/2006 Consumer United States
Primary
Concomitant
Weight Decreased 10/11/2005 52 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 4/1/2006 60 Male 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/2/2005 Female 185 lb 8/23/2006 Consumer United States
Primary
Concomitant
Urticaria Hospitalization 8/1/2006 57 Female 11/8/2006 Consumer United States
Primary
Concomitant
Hypokalaemia Hospitalization 10/31/2006 Female 11/22/2006 Consumer United States
Primary
Concomitant
Pruritus 6/14/2007 74 Female 8/16/2007 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/21/2007 76 Female 12/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 1/4/2008 Female 3/14/2008 Peru
Primary
Concomitant
Road Traffic Accident 1/11/2008 Female 275 lb 3/15/2008 United States
Primary
Concomitant
Rectal Haemorrhage 12/1/2007 Female 170 lb 3/15/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 1/31/2008 Female 195 lb 3/15/2008 Other Health Professional United States
Primary
Concomitant
Mental Impairment 2/16/2008 3/15/2008 United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Male 9/16/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 46 Female 10/15/2008 Other Health Professional United States
Primary
Concomitant
Vision Blurred Hospitalization 46 Female 390 lb 11/6/2008 Pharmacist United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Hospitalization 8/19/2008 1/5/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 1/15/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 2/1/2006 52 Female 271 lb 1/16/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 2/1/2006 52 Female 271 lb 1/21/2009 Consumer United States
Primary
Concomitant
Renal Failure Death 1/1/2009 Female 1/22/2009 Physician United States
Primary
Concomitant
Dyskinesia Hospitalization 1/1/1998 55 Female 1/23/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 66 Male 2/20/2009 Physician Hungary
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 2/1/2006 52 Female 271 lb 2/24/2009 Other Health Professional United States
Primary
Concomitant
Headache 11/11/2008 Male 2/24/2009 United States
Primary
Concomitant
Flushing 12/1/2008 Female 2/24/2009 United States
Primary
Concomitant
Eye Haemorrhage Other Serious 3/1/2008 74 Male 168 lb 2/25/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 235 lb 3/6/2009 Physician United States
Primary
Concomitant
Swelling Face Other Serious 1/1/2008 Male 146 lb 4/22/2009 Consumer United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/1/2008 Male 146 lb 5/28/2009 Consumer United States
Primary
Secondary
Concomitant
Toxic Encephalopathy Life Threatening 2/1/2009 Male 6/9/2009 Physician United States
Primary
Concomitant
Tremor 1/1/2009 80 Female 6/12/2009 Consumer United States
Primary
Concomitant
Renal Failure Life Threatening 57 Female 6/17/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2008 Female 187 lb 6/22/2009 Physician United States
Primary
Concomitant
Phaeochromocytoma Other Serious 4/21/2008 Female 136 lb 7/1/2009 Other Health Professional United States
Primary
Concomitant
Wheelchair User Disability 3/1/2009 Male 7/9/2009 United States
Primary
Concomitant
Weight Increased Life Threatening 57 Female 7/21/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 59 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/29/2009 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 43 Female 233 lb 7/30/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 6/16/2009 55 Male 254 lb 7/31/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 6/16/2009 55 Male 254 lb 7/31/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 6/16/2009 55 Male 254 lb 8/3/2009 United States
Primary
Concomitant
Wound Abscess Other Serious 1/9/2009 Male 8/3/2009 Physician United States
Primary
Concomitant
Vomiting Death 1/1/2007 70 Female 165 lb 7/29/2009 Physician United States
Primary
Concomitant
Rash Hospitalization 1/1/2007 Female 8/3/2009 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/4/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/7/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Life Threatening 57 Female 8/3/2009 United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 6/1/2009 Male 8/12/2009 Portugal
Primary
Concomitant
Skin Burning Sensation Female 8/21/2009 United States
Primary
Concomitant
Vomiting 8/13/2008 Male 240 lb 8/21/2009 Consumer United States
Primary
Concomitant
Pain In Extremity 9/25/2008 Female 219 lb 8/22/2009 United States
Primary
Secondary
Concomitant
Nausea 10/1/2008 Female 200 lb 8/22/2009 United States
Primary
Concomitant
Nocturia Other Serious 8/19/2009 56 9/9/2009 Consumer Brazil
Primary
Concomitant
Weight Increased Other Serious 5/1/2002 56 10/9/2009 Consumer Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/13/2008 Male 10/22/2009 Physician United States
Primary
Secondary
Concomitant
Venous Insufficiency Hospitalization 82 Male 10/23/2009 Lawyer United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/22/2009 Lawyer United States
Primary
Concomitant
Drug Administered At Inappropriate Site 10/18/2009 Female 197 lb 11/2/2009 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 5/1/2002 56 Male 216 lb 11/3/2009 Physician Brazil
Primary
Secondary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/27/2009 Lawyer United States
Primary
Concomitant
Injury Hospitalization 6/12/2009 73 Male 198 lb 11/6/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/3/2009 Female 190 lb 11/5/2009 United States
Primary
Concomitant
Vomiting Life Threatening 8/1/2009 57 Male 141 lb 11/16/2009 Other Health Professional France
Primary
Secondary
Concomitant
Injury Hospitalization 6/12/2009 73 Male 198 lb 11/18/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/1/2009 57 Male 141 lb 11/20/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 11/24/2009 Consumer United States
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 68 Male 12/11/2009 United States
Primary
Concomitant
Pain 6/1/2009 Female 158 lb 12/31/2009 Consumer United States
Primary
Concomitant
Cerebral Haematoma Death 12/21/2009 Female 1/11/2010 Physician Netherlands
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 1/20/2010 Physician United States
Primary
Secondary
Concomitant
Pain Death Male 1/11/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2000 57 Female 186 lb 1/25/2010 United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 62 Male 229 lb 1/22/2010 United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 66 Male 2/9/2010 Physician Hungary
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/1/2009 57 Male 141 lb 3/5/2010 Other Health Professional France
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 3/5/2010 Physician United States
Primary
Secondary
Concomitant
Rash Macular Other Serious 3/4/2010 Female 175 lb 3/17/2010 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 7/1/2007 Male 201 lb 3/19/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 9/1/2008 Female 172 lb 3/19/2010 Consumer United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 2/1/2010 67 Female 249 lb 4/9/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 5/1/2002 54 Male 216 lb 4/13/2010 Physician Brazil
Primary
Secondary
Concomitant
Pancreatitis Chronic Other Serious 1/1/2008 48 Female 238 lb 4/21/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Angioplasty Hospitalization 51 Male 4/30/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 3/9/2010 85 Female 5/5/2010 Physician France
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 3/2/2010 47 Female 5/13/2010 Other Health Professional France
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 61 Male 256 lb 6/1/2010 Physician United States
Primary
Concomitant
Renal Injury Other Serious 7/24/2008 70 Female 189 lb 6/11/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 6/2/2010 77 Male 180 lb 6/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 68 Female 280 lb 6/16/2010 Other Health Professional United States
Primary
Concomitant
Surgery Hospitalization 51 Male 6/16/2010 United States
Primary
Concomitant
Pancreatitis Other Serious 3/27/2010 43 Male 6/16/2010 Physician United States
Primary
Concomitant
Haemorrhage Intracranial Hospitalization 48 Male 6/22/2010 Physician United States
Primary
Concomitant
Depression Other Serious 1/1/1995 61 Male 132 lb 6/25/2010 Pharmacist France
Primary
Concomitant
Unevaluable Event Hospitalization 5/16/2010 70 Female 7/12/2010 Consumer United States
Primary
Concomitant
Vomiting 5/1/2007 69 Female 168 lb 7/13/2010 Consumer United States
Primary
Secondary
Concomitant
Uterine Disorder Other Serious 2/3/2003 31 Female 249 lb 7/14/2010 United States
Primary
Concomitant
Drug Ineffective 6/1/2008 48 Female 7/22/2010 Other Health Professional United States
Primary
Concomitant
Nausea 7/1/2008 55 Female 160 lb 7/22/2010 Consumer United States
Primary
Concomitant
Social Avoidant Behaviour Other Serious 4/3/2008 58 Male 8/13/2010 Lawyer United States
Primary
Concomitant
Pruritus 5/1/2010 38 Male 263 lb 8/16/2010 Consumer United States
Primary
Concomitant
Walking Aid User Other Serious 7/1/2004 74 Female 8/17/2010 United States
Primary
Secondary
Concomitant
Eye Infection Fungal Other Serious 2/1/2010 53 Female 179 lb 8/20/2010 Other Health Professional Canada
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization 8/19/2008 64 Male 134 lb 8/24/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Dyspnoea Other Serious 7/20/2010 46 Female 186 lb 8/19/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 52 Female 8/18/2010 United States
Primary
Concomitant
Hyperhidrosis 7/1/2009 70 Male 215 lb 8/27/2010 Consumer United States
Primary
Concomitant
Pain 3/8/2010 42 Male 225 lb 8/28/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1999 30 Male 145 lb 9/6/2010 United States
Primary
Concomitant
Respiratory Distress Other Serious 8/24/2010 74 Female 165 lb 9/10/2010 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 68 Female 280 lb 9/15/2010 Other Health Professional United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 61 Male 256 lb 9/16/2010 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 12/5/2005 51 Male 9/17/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 4/1/2005 45 Male 430 lb 9/17/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 8/1/2009 57 Male 9/17/2010 Other Health Professional United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 4/18/2003 45 Male 286 lb 9/20/2010 United States
Primary
Concomitant
Therapeutic Response Unexpected 56 Male 186 lb 9/20/2010 United States
Primary
Concomitant
Walking Disability Hospitalization 1/1/2000 60 Female 218 lb 9/20/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/1/2004 41 Male 315 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/1/2003 49 Female 146 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 38 Female 279 lb 9/20/2010 United States
Primary
Concomitant

Drug Data