Alprazolam combined with Hydromorphone Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyuria Other Serious 1/6/2006 53 Male 1/19/2006 Pharmacist United States
Primary
Concomitant
Nephritis Interstitial Other Serious 1/6/2006 53 Male 4/27/2006 Pharmacist United States
Primary
Concomitant
Self-medication Other Serious 4/25/2006 28 Female 8/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
Perivascular Dermatitis Other Serious 1/1/2006 76 Female 120 lb 7/19/2006 Physician United States
Primary
Concomitant
Accidental Overdose Death 3/9/2001 44 Male 176 lb 7/17/2006 Consumer United States
Primary
Secondary
Nausea Hospitalization 8/7/2006 59 Female 157 lb 8/31/2006 Consumer United States
Primary
Secondary
Concomitant
Sensation Of Pressure Hospitalization 8/21/2006 59 Female 152 lb 9/1/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2005 10/12/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 Unknown 10/12/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 11/9/2006 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 11/21/2006 Physician United States
Primary
Secondary
Sleep Walking Other Serious 1/4/2003 Female 4/13/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/8/2007 50 Female 4/23/2007 Consumer Canada
Primary
Secondary
Concomitant
Loss Of Consciousness Required Intervention 4/11/2007 35 Male 240 lb 4/24/2007 Other Health Professional United States
Primary
Concomitant
Muscular Weakness Hospitalization 1/1/2005 Female 160 lb 7/24/2007 Consumer United States
Primary
Secondary
Concomitant
Gastritis Other Serious 1/1/2004 Male 188 lb 8/29/2007 Consumer United States
Primary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 7/18/2007 47 Female 126 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Life Threatening 7/18/2007 47 Female 11/6/2007 United States
Primary
Secondary
Concomitant
Bronchitis Hospitalization 10/24/2007 Male 130 lb 11/14/2007 Physician United States
Primary
Secondary
Concomitant
Gastritis Other Serious 1/1/2004 Male 188 lb 12/7/2007 Consumer United States
Primary
Concomitant
Diverticulitis Hospitalization 11/9/2007 63 Female 198 lb 12/18/2007 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 11/9/2007 63 Female 198 lb 12/18/2007 Physician United States
Primary
Secondary
Concomitant
Bronchitis Hospitalization 10/24/2007 Male 130 lb 1/11/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/15/2007 Female 1/24/2008 Physician United States
Primary
Secondary
Vomiting Life Threatening 10/15/2007 Female 2/4/2008 Physician United States
Primary
Secondary
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Serum Sickness Hospitalization 1/1/2007 54 Male 179 lb 1/25/2008 Pharmacist United States
Primary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 3/26/2008 Lawyer United States
Primary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 5/1/2008 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 8/1/2007 Female 245 lb 5/2/2008 Physician United States
Primary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 5/14/2008 Lawyer United States
Primary
Concomitant
Thyroid Adenoma Death 2/2/2008 43 Male 178 lb 6/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 8/7/2008 Lawyer United States
Primary
Concomitant
Tooth Extraction Other Serious 3/1/2005 Male 8/13/2008 United States
Primary
Secondary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 8/19/2008 Lawyer United States
Primary
Concomitant
Pharmaceutical Product Complaint Death 4/10/2008 67 Female 8/22/2008 Lawyer United States
Primary
Concomitant
Dehydration Hospitalization 8/20/2008 Female 199 lb 9/10/2008 Consumer United States
Primary
Secondary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 9/10/2008 Lawyer United States
Primary
Concomitant
Dehydration Hospitalization 8/20/2008 Female 199 lb 9/19/2008 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Death 1/1/2005 Male 9/17/2008 Physician United States
Primary
Secondary
Pancytopenia Required Intervention 4/17/2007 54 Male 160 lb 9/18/2007 Physician United States
Primary
Concomitant
Product Quality Issue Death 4/10/2008 67 Female 8/22/2008 Lawyer United States
Primary
Concomitant
Tooth Extraction Other Serious Female 1/14/2009 United States
Primary
Secondary
Concomitant
Splenomegaly Other Serious 12/1/2006 Male 1/29/2009 Lawyer United States
Primary
Concomitant
Neoplasm Progression Death Male 122 lb 2/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious Female 3/2/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2003 Female 4/11/2009 Pharmacist United States
Primary
Secondary
Concomitant
Wound Hospitalization 2/10/2002 40 Male 194 lb 5/20/2009 United States
Primary
Concomitant
Silicon Granuloma Hospitalization 53 Female 7/9/2009 Physician United States
Primary
Secondary
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Psychomotor Hyperactivity Hospitalization 4/6/2009 67 Female 9/2/2009 Physician Switzerland
Primary
Secondary
Transient Ischaemic Attack Hospitalization 61 Female 10/17/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 56 Female 11/18/2009 United States
Primary
Concomitant
Respiratory Arrest Death 50 Female 1/25/2010 Physician United States
Primary
Secondary
Poisoning Death 59 Male 1/26/2010 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 59 Male 3/3/2010 Physician United States
Primary
Secondary
Tooth Extraction Other Serious 7/23/2004 Female 119 lb 3/19/2010 Other Health Professional United States
Primary
Concomitant
Skin Tightness Other Serious 1/1/2005 49 Male 168 lb 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 1/1/2008 50 Female 4/6/2010 Physician United States
Primary
Secondary
Tooth Extraction Other Serious 7/23/2004 49 Female 119 lb 4/15/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Skin Tightness Other Serious 1/1/2005 49 Male 168 lb 4/30/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 7/23/2004 49 Female 119 lb 5/6/2010 United States
Primary
Concomitant
Vomiting Other Serious 59 Female 4/27/2010 United States
Primary
Concomitant
Respiratory Failure Other Serious 1/1/1996 44 Male 5/24/2010 Other Health Professional United States
Primary
Concomitant
No Adverse Event Hospitalization 12/1/2009 33 Female 6/7/2010 Other Health Professional United States
Primary
Concomitant
Wound Dehiscence Other Serious 3/1/2005 39 Male 6/7/2010 United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 25 Female 6/11/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Other Serious Male 9/20/2010 United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 8/2/2010 57 Male 9/20/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2000 34 Male 9/27/2010 United States
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 8/2/2010 57 Male 9/30/2010 Physician United States
Primary
Concomitant
Neck Pain Other Serious 11/12/2008 65 Female 10/5/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2000 34 Male 10/19/2010 United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 2/1/2003 51 Female 11/22/2010 Pharmacist United States
Primary
Secondary
Concomitant
Upper Airway Obstruction Required Intervention 5/1/2007 48 Female 180 lb 12/14/2010 Consumer United States
Primary
Concomitant
Skin Induration Other Serious 1/1/2005 48 Male 168 lb 1/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Steatosis Hospitalization 1/1/2005 39 Male 1/10/2011 Pharmacist United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Accidental Death 8/24/2010 46 Female 2/25/2011 Consumer United States
Primary
Secondary
Multiple Drug Overdose Accidental Death 8/24/2010 46 Female 3/22/2011 United States
Primary
Secondary
Large Intestinal Haemorrhage Death Female 3/24/2011 Physician United States
Primary
Secondary
Cardiac Failure Congestive Hospitalization 1/1/2006 27 Female 140 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Cataract Nuclear Hospitalization 3/1/2005 72 Male 4/7/2011 Other Health Professional United States
Primary
Concomitant
Hypoaesthesia Hospitalization 1/1/2005 39 Male 5/13/2011 Pharmacist United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 3/1/2005 72 Male 5/13/2011 Lawyer United States
Primary
Concomitant
Osteoarthritis Hospitalization 1/1/2005 39 Male 5/24/2011 United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 11/17/2010 54 Female 118 lb 5/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/21/2003 Male 6/1/2011 United States
Primary
Concomitant
Abdominal Pain 12/31/2010 47 Male 155 lb 5/11/2011 Other Health Professional United States
Primary
Concomitant
Postoperative Wound Complication Other Serious 1/1/2005 39 Male 6/23/2011 Physician United States
Primary
Secondary
Concomitant
Blood Cholesterol Increased Hospitalization 3/1/2005 72 Male 6/27/2011 United States
Primary
Concomitant
Lichenoid Keratosis Other Serious 1/1/2003 56 Female 155 lb 7/7/2011 Pharmacist United States
Primary
Secondary
Concomitant
Lung Adenocarcinoma Other Serious Male 7/11/2011 Physician United States
Primary
Concomitant
Dizziness Hospitalization 3/1/2005 72 Male 7/12/2011 Lawyer United States
Primary
Concomitant
Injury Disability Male 7/14/2011 Lawyer United States
Primary
Concomitant
Toxicity To Various Agents Death 2/4/2011 31 Female 154 lb 7/11/2011 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Death 6/24/2011 52 Male 7/21/2011 Pharmacist United States
Primary
Concomitant
Discomfort Death 7/19/2011 60 Male 7/21/2011 Consumer United States
Primary
Concomitant
Interacting
Toxicity To Various Agents Death 15 Male 7/25/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 50 Female 7/21/2011 Physician United States
Primary
Secondary
Primary Sequestrum Other Serious 1/1/2005 39 Male 8/3/2011 Pharmacist United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/1/2003 51 Female 8/4/2011 Pharmacist United States
Primary
Secondary
Concomitant
Paronychia Other Serious Male 8/4/2011 Physician United States
Primary
Concomitant
Excessive Granulation Tissue Hospitalization 1/1/2003 56 Female 155 lb 8/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization Female 237 lb 8/9/2011 Physician United States
Primary
Concomitant
Dysplastic Naevus Other Serious 1/1/2003 56 Female 155 lb 8/11/2011 United States
Primary
Secondary
Concomitant
Vomiting 7/1/2011 50 Female 8/11/2011 Pharmacist United States
Primary
Concomitant
Tachycardia Hospitalization 50 Male 121 lb 8/18/2011 Consumer United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Female 145 lb 8/22/2011 United States
Primary
Concomitant
Fatigue Other Serious 1/1/2003 56 Female 155 lb 8/20/2011 Consumer United States
Primary
Secondary
Concomitant
Pleural Fibrosis Hospitalization 3/1/2005 72 Male 8/20/2011 Lawyer United States
Primary
Concomitant
Pelvic Pain Other Serious 46 Female 8/22/2011 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 46 Female 8/23/2011 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 50 Male 121 lb 8/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tendon Disorder Other Serious 1/1/2003 56 Female 155 lb 8/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sensory Disturbance Other Serious 1/1/2005 39 Male 215 lb 8/26/2011 United States
Primary
Secondary
Concomitant
Testicular Pain Other Serious Male 8/30/2011 Lawyer United States
Primary
Concomitant
Asthenia Other Serious 2/15/2008 48 Female 8/31/2011 Lawyer United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 9/28/2010 15 Male 9/1/2011 Physician United States
Primary
Secondary
Lung Adenocarcinoma Other Serious Male 9/6/2011 Physician United States
Primary
Concomitant
Toxicity To Various Agents Death 9/28/2010 15 Male 9/20/2011 Physician United States
Primary
Secondary
Arteriosclerosis Other Serious Male 9/22/2011 Lawyer United States
Primary
Concomitant
Fatigue 9/21/2011 48 Female 102 lb 9/21/2011 Pharmacist United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2006 27 Female 174 lb 9/27/2011 Consumer United States
Primary
Concomitant
Multiple Drug Overdose Death 9/28/2010 15 Male 9/28/2011 Consumer United States
Primary
Secondary
Blood Urine Present Other Serious Male 10/5/2011 Consumer United States
Primary
Concomitant
Multiple Drug Overdose Death 24 Male 10/17/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 20 10/24/2011 Consumer United States
Primary
Interacting
Sensory Disturbance Other Serious 1/1/2005 39 Male 215 lb 10/28/2011 Physician United States
Primary
Secondary
Concomitant
Respiratory Depression Death 20 11/4/2011 Consumer United States
Primary
Interacting
Economic Problem Other Serious 70 Female 220 lb 11/2/2011 Lawyer United States
Primary
Concomitant
Incorrect Dose Administered Death 1/1/2010 67 Male 11/10/2011 Physician United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 1/1/2011 52 Female 139 lb 11/11/2011 Physician United States
Primary
Secondary
Concomitant
Fibula Fracture Hospitalization Male 11/15/2011 Physician United States
Primary
Concomitant
Sepsis Death 1/1/2008 64 Female 130 lb 11/8/2011 United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 59 Male 11/21/2011 Pharmacist United States
Primary
Concomitant
Transitional Cell Cancer Of The Renal Pelvis And Ureter Hospitalization 1/1/2011 79 Male 11/23/2011 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 2/1/2003 51 Female 11/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Other Serious Male 11/25/2011 Lawyer United States
Primary
Concomitant
Urethral Obstruction Disability Male 12/2/2011 Lawyer United States
Primary
Concomitant
Diarrhoea Hospitalization 6/10/2010 52 Male 227 lb 12/8/2011 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 1/1/2011 52 Female 139 lb 12/8/2011 Physician United States
Primary
Secondary
Concomitant
Large Intestinal Ulcer Other Serious 12/11/2009 53 Female 145 lb 12/13/2011 Lawyer United States
Primary
Concomitant
Chest Pain Other Serious 71 Male 12/22/2011 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2010 55 Male 12/22/2011 Physician United States
Primary
Secondary
Death Death 51 Female 12/30/2011 Physician United States
Primary
Secondary
Osteoarthritis Other Serious Male 1/1/2012 Physician United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 43 Female 210 lb 11/6/2011 Consumer United States
Primary
Concomitant

Drug Data