Alprazolam combined with Heparin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 11/23/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 1/6/2006 Physician United States
Primary
Concomitant
Tachycardia Other Serious 4/3/2005 68 Male 154 lb 1/11/2006 Physician Colombia
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 6/15/2005 66 Male 198 lb 2/9/2006 Poland
Primary
Concomitant
Interacting
Anaphylactic Shock Life Threatening 1/13/2006 43 Female 3/4/2006 France
Primary
Secondary
Concomitant
Jaw Cyst Hospitalization 3/25/2004 65 Male 176 lb 4/3/2006 Physician United States
Primary
Concomitant
Peritonitis Hospitalization 5/23/2005 53 Male 191 lb 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 5/15/2006 50 Male 7/14/2006 Argentina
Primary
Concomitant
Contrast Media Reaction Disability 10/21/2005 50 Female 169 lb 8/15/2006 Pharmacist United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/13/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
Haemorrhage Required Intervention 8/16/2006 78 Female 150 lb 10/2/2006 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 1/9/2007 72 Female 3/9/2007 Physician France
Primary
Concomitant
Septic Shock Other Serious 2/10/2007 64 Male 3/28/2007 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Required Intervention 4/11/2007 35 Male 240 lb 4/24/2007 Other Health Professional United States
Primary
Concomitant
Multiple Myeloma Death 4/18/2007 71 Female 4/27/2007 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/18/2006 64 Female 146 lb 4/30/2007 Pharmacist United States
Primary
Concomitant
Multiple Myeloma Death 4/18/2007 71 Female 6/11/2007 Physician United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 71 Female 6/25/2007 Physician United States
Primary
Secondary
Concomitant
Exercise Tolerance Decreased Hospitalization 7/4/2007 Female 119 lb 7/17/2007 Argentina
Primary
Concomitant
Intracranial Pressure Increased Other Serious 2/5/2007 40 Male 271 lb 5/15/2007 Pharmacist United States
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 6/1/2004 Male 9/5/2007 United Kingdom
Primary
Secondary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 58 Female 228 lb 10/1/2007 Physician United States
Primary
Concomitant
Vascular Pseudoaneurysm Other Serious 6/21/2007 78 Female 10/9/2007 Physician Spain
Primary
Secondary
Concomitant
Vascular Pseudoaneurysm Other Serious 6/21/2007 78 Female 10/9/2007 Physician Spain
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 7/18/2007 47 Female 126 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 9/20/2007 69 Male 11/1/2007 Physician Belgium
Primary
Concomitant
Nausea Life Threatening 7/18/2007 47 Female 11/6/2007 United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/7/2007 63 Male 165 lb 11/26/2007 Pharmacist United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 79 Female 12/22/2007 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 79 Female 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Microangiopathic Haemolytic Anaemia Other Serious 76 Female 2/22/2008 Physician United States
Primary
Secondary
Concomitant
Aspergillosis Death 1/20/2008 Male 4/2/2008 Physician France
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 7/4/2007 Female 119 lb 4/28/2008 Argentina
Primary
Concomitant
Sepsis Other Serious 3/3/2008 Female 148 lb 5/28/2008 Physician Belgium
Primary
Concomitant
Sepsis Other Serious 3/3/2008 Female 148 lb 7/10/2008 Physician Belgium
Primary
Concomitant
Hallucination, Visual Hospitalization 9/6/2007 94 Female 193 lb 7/15/2008 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Life Threatening 2/14/2008 78 Male 229 lb 8/14/2008 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 58 Female 228 lb 10/15/2008 United States
Primary
Concomitant
Transient Ischaemic Attack Life Threatening 10/11/2006 Female 11/7/2008 Consumer France
Primary
Secondary
Concomitant
Transient Ischaemic Attack Life Threatening 10/11/2006 Female 11/11/2008 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Required Intervention 9/6/2008 58 Female 172 lb 10/3/2008 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 12/11/2008 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 12/18/2008 Consumer United States
Primary
Secondary
Concomitant
Retching Other Serious 11/12/2008 Female 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 1/8/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 1/15/2009 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 7/14/2008 Female 205 lb 2/2/2009 United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 10/5/2008 57 Male 2/3/2009 Consumer France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/21/2009 Male 174 lb 2/11/2009 Physician Argentina
Primary
Secondary
Concomitant
Transient Ischaemic Attack Life Threatening 10/11/2006 Female 2/20/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 3/2/2009 Consumer United States
Primary
Secondary
Concomitant
Microangiopathic Haemolytic Anaemia Other Serious 76 Female 3/25/2009 Physician United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 4/14/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 4/22/2009 Consumer United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Retching Other Serious 11/12/2008 Female 5/8/2009 Consumer United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 9/10/2008 42 Male 5/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 6/1/2008 21 Male 216 lb 5/11/2009 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 5/29/2009 Consumer United States
Primary
Secondary
Concomitant
Diabetic Retinopathy Other Serious 8/20/2001 46 Male 177 lb 6/5/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2001 47 Female 285 lb 7/10/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/16/2009 Consumer United States
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 5/28/2009 Male 7/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 5/23/2009 Male 7/24/2009 Other Health Professional France
Primary
Concomitant
Interacting
Splenic Infarction Other Serious 5/28/2009 25 Male 7/21/2009 Other Health Professional France
Primary
Concomitant
Torsade De Pointes Life Threatening 5/28/2009 25 7/27/2009 Other Health Professional France
Primary
Concomitant
Interacting
Pulmonary Embolism Other Serious 11/12/2008 Female 7/29/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/4/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/7/2009 Consumer United States
Primary
Secondary
Concomitant
Ventricular Failure Hospitalization 49 Female 9/14/2009 United States
Primary
Concomitant
Ventricular Fibrillation Required Intervention 10/28/2008 Male 202 lb 10/30/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 77 Female 9/25/2009 United States
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 70 Male 10/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 70 Male 10/3/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 70 Male 10/2/2009 Physician United States
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 70 Male 10/13/2009 Physician United States
Primary
Secondary
Concomitant
Streptococcal Infection Hospitalization 70 Male 10/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 70 Male 10/22/2009 Physician France
Primary
Secondary
Ventricular Failure Hospitalization 49 Female 10/16/2009 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 11/10/2009 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 70 Male 11/19/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 11/24/2009 Consumer United States
Primary
Secondary
Concomitant
Haematoma Other Serious 11/19/2009 25 Male 193 lb 12/17/2009 Pharmacist United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 1/5/2009 42 Male 12/31/2009 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Ventricular Tachycardia Other Serious 65 Female 1/25/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis In Device Death 3/6/2008 Female 220 lb 1/25/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis In Device Death 3/6/2008 Female 220 lb 1/26/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2007 58 Female 2/4/2010 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2010 Male 2/16/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 11/1/2009 Female 121 lb 3/5/2010 Consumer Japan
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 1/1/2001 47 Female 285 lb 4/19/2010 United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2010 66 Male 4/30/2010 Physician United States
Primary
Concomitant
Electrocardiogram Qrs Complex Prolonged Death 1/1/2010 81 Male 128 lb 5/11/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Life Threatening 10/22/2008 89 Female 165 lb 5/24/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Required Intervention 7/1/2010 67 Male 253 lb 7/14/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2005 56 Female 123 lb 7/29/2010 United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 34 Female 216 lb 8/2/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 5/22/2002 64 Male 185 lb 9/1/2010 United States
Primary
Concomitant
Throat Tightness Other Serious 4/8/2010 44 Female 101 lb 7/26/2010 Physician United States
Primary
Concomitant
Rash Maculo-papular Other Serious 9/2/2010 62 Female 356 lb 9/3/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2005 56 Female 123 lb 10/6/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/22/2002 64 Male 185 lb 10/7/2010 United States
Primary
Concomitant
Vomiting Other Serious 5/22/2002 64 Male 185 lb 10/7/2010 United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 10/21/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 5/22/2002 64 Male 185 lb 10/22/2010 United States
Primary
Concomitant
Vomiting Other Serious 5/22/2002 64 Male 185 lb 10/26/2010 United States
Primary
Concomitant
Confusional State Hospitalization 7/21/2009 65 Male 255 lb 11/12/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2005 56 Female 123 lb 11/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Injury Hospitalization 9/11/2010 55 Male 12/3/2010 Physician France
Primary
Concomitant
Vomiting Other Serious 5/22/2002 64 Male 185 lb 12/14/2010 United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 11/25/2010 85 Female 186 lb 12/22/2010 Physician Argentina
Primary
Concomitant
Weight Decreased Other Serious 11/1/2005 56 Female 123 lb 12/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 11/1/2005 56 Female 123 lb 1/7/2011 Lawyer United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 11/1/2005 56 Female 123 lb 1/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Colonic Polyp Other Serious 5/22/2002 64 Male 185 lb 1/21/2011 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/5/2011 77 Male 223 lb 1/21/2011 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 11/25/2010 85 Female 186 lb 2/1/2011 Physician Argentina
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/11/2011 70 Male 132 lb 2/14/2011 Consumer Germany
Primary
Secondary
Concomitant
Skin Hypertrophy Other Serious 1/1/2005 54 Male 2/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/5/2011 77 Male 223 lb 2/25/2011 Physician United States
Primary
Secondary
Concomitant
Myoclonic Epilepsy Hospitalization 5/28/2009 25 Male 3/4/2011 Other Health Professional France
Primary
Concomitant
Interacting
Electrocardiogram Qt Prolonged Hospitalization 1/11/2011 70 Male 132 lb 3/4/2011 Consumer Germany
Primary
Secondary
Concomitant
Myoclonic Epilepsy Hospitalization 5/23/2009 25 Male 3/4/2011 Other Health Professional France
Primary
Concomitant
Interacting
Constipation Hospitalization 2/9/2011 83 Male 146 lb 2/28/2011 Other Health Professional United States
Primary
Concomitant
Torsade De Pointes Hospitalization 5/23/2009 25 Male 3/8/2011 Other Health Professional France
Primary
Concomitant
Interacting
Hydronephrosis Hospitalization 1/19/2011 67 Male 207 lb 2/28/2011 Physician United States
Primary
Concomitant
Cholangitis Hospitalization Female 3/15/2011 Consumer United States
Primary
Secondary
Concomitant
Nephrogenic Anaemia Other Serious 1/19/2011 67 Male 207 lb 3/4/2011 Physician United States
Primary
Concomitant
Hyperkalaemia Hospitalization 3/3/2011 66 Female 198 lb Pharmacist United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 1/11/2011 70 Male 132 lb 4/8/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Injury Other Serious 59 Female 3/29/2011 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 8/10/2006 72 Male 187 lb 4/21/2011 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Tube Insertion Hospitalization Male 4/25/2011 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/11/2011 70 Male 132 lb 4/27/2011 Consumer Germany
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 1/11/2011 70 Male 132 lb 4/28/2011 Consumer Germany
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 1/11/2011 70 Male 132 lb 5/17/2011 Consumer Germany
Primary
Secondary
Concomitant
Anhedonia Other Serious 2/4/2005 54 Male 271 lb 5/19/2011 Other Health Professional United States
Primary
Concomitant
Respiratory Arrest Other Serious Female 154 lb 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Psychiatric Symptom Hospitalization 8/1/2006 80 Female 185 lb 6/4/2011 Consumer United States
Primary
Concomitant
Emotional Distress Other Serious 6/24/2005 75 Female 158 lb 6/7/2011 Other Health Professional United States
Primary
Concomitant
Fear Other Serious 4/29/2005 78 Male 210 lb 6/8/2011 Consumer United States
Primary
Concomitant
General Physical Health Deterioration Other Serious 10/21/1998 66 Male 161 lb 6/18/2011 Consumer United States
Primary
Concomitant
Drug Prescribing Error Other Serious 4/5/2011 46 Female 154 lb 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 1/1/2003 65 Male 265 lb 6/29/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 1/9/2004 79 Female 150 lb 7/8/2011 Physician United States
Primary
Concomitant

Drug Data