Alprazolam combined with Fentanyl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lethargy Death 12/9/2005 62 Male 1/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 2/11/2006 65 Female 149 lb 2/15/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 12/16/2005 46 Female 2/28/2006 Physician Brazil
Primary
Concomitant
Sepsis Other Serious 12/16/2005 46 Female 3/13/2006 Physician Brazil
Primary
Concomitant
Pyrexia Other Serious 7/8/2005 55 Male 3/24/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 4/10/2006 Physician United States
Primary
Concomitant
Sepsis Other Serious 1/10/2006 38 Male 176 lb 4/5/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/24/2006 57 Female 140 lb 3/30/2006 Consumer United States
Primary
Concomitant
Death Death 3/1/2006 51 Female 4/12/2006 United States
Primary
Concomitant
Urinary Tract Disorder Hospitalization 9/30/2004 63 Male 240 lb 4/17/2006 United States
Primary
Concomitant
Death Death 3/28/2006 51 Female 5/1/2006 United States
Primary
Concomitant
Urinary Retention Hospitalization 9/30/2004 63 Male 240 lb 5/5/2006 United States
Primary
Concomitant
Polysubstance Abuse Other Serious 8/30/2003 38 Male 178 lb 5/12/2006 United States
Primary
Secondary
Polysubstance Abuse Death 7/13/2005 45 Female 136 lb 5/23/2006 Physician United States
Primary
Secondary
Polysubstance Abuse Death 7/13/2005 45 Female 136 lb 5/25/2006 Other Health Professional United States
Primary
Secondary
Respiratory Acidosis Life Threatening 32 Male 6/7/2006 India
Primary
Secondary
Concomitant
Drug Withdrawal Syndrome Hospitalization 9/14/2005 36 Male 247 lb 5/9/2006 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Death 21 Male 6/14/2006 United States
Primary
Secondary
Drug Toxicity Death 24 Male 212 lb 6/14/2006 Physician United States
Primary
Secondary
Vein Disorder Life Threatening 4/20/2006 53 Male 121 lb 7/20/2006 Physician France
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/1/2006 36 Male 210 lb 8/2/2006 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/24/2004 22 Male 8/1/2006 Other Health Professional United States
Primary
Concomitant
Venous Thrombosis Other Serious 4/1/2006 55 Female 105 lb 8/14/2006 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 10/24/2005 74 Female 8/15/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/23/2006 Female 129 lb 8/2/2006 Pharmacist United States
Primary
Concomitant
Substance Abuse Death 11/4/2003 47 Female 150 lb 7/17/2006 Other Health Professional United States
Primary
Secondary
Somnolence Other Serious 10/24/2005 74 Female 8/25/2006 Physician Japan
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 46 Female 8/31/2006 Other Health Professional United States
Primary
Secondary
Wound Other Serious Female 128 lb 9/8/2006 Consumer Canada
Primary
Concomitant
Panic Attack Hospitalization 4/11/2005 Female 128 lb 9/11/2006 Consumer Canada
Primary
Concomitant
Death Death 52 Female 9/12/2006 Physician United States
Primary
Secondary
Panic Attack Hospitalization 4/11/2005 Female 128 lb 9/14/2006 Consumer Canada
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 8/29/2006 44 Female 118 lb 10/31/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 9/30/2004 63 Male 240 lb 11/7/2006 United States
Primary
Concomitant
Weight Decreased Hospitalization 9/30/2004 63 Male 240 lb 11/20/2006 United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2005 49 11/21/2006 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2005 49 11/21/2006 Physician United States
Primary
Secondary
Osteopenia Hospitalization 8/4/2005 61 Male 12/26/2006 Physician Belgium
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 49 1/26/2007 Physician United States
Primary
Secondary
Multiple Drug Overdose Death 51 Male 2/8/2007 United States
Primary
Secondary
Concomitant
Osteopenia Hospitalization 8/4/2005 61 Male 3/1/2007 Physician Belgium
Primary
Secondary
Concomitant
Death Death 48 Female 4/24/2007 Physician
Primary
Concomitant
Death Death 48 Female 4/26/2007 Physician
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 12/23/2005 51 Female 121 lb 5/24/2007 Other Health Professional United States
Primary
Concomitant
Somnolence 1/1/2006 40 Male 118 lb 3/13/2007 Consumer United States
Primary
Concomitant
Oxygen Saturation Decreased Life Threatening 6/15/2007 Male 163 lb 6/22/2007 Consumer United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 71 Female 6/25/2007 Physician United States
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 1/1/2006 Female 7/20/2007 Physician Belgium
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2007 Male 135 lb 8/15/2007 Consumer United States
Primary
Secondary
Concomitant
Death Death 5/1/2007 Male 9/10/2007 Pharmacist United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 12/23/2005 51 Female 121 lb 9/11/2007 Other Health Professional United States
Primary
Concomitant
Repetitive Strain Injury Other Serious 1/1/2006 70 Female 9/11/2007 Consumer United States
Primary
Concomitant
Vascular Resistance Systemic Decreased Hospitalization 2/13/2007 79 Male 224 lb 8/6/2007 Physician United States
Primary
Concomitant
Peroneal Nerve Palsy Other Serious 9/1/2006 70 Female 9/20/2007 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 8/1/2006 Male 162 lb 10/12/2007 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 8/1/2006 Male 162 lb 11/29/2007 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 9/7/2007 63 Male 165 lb 11/26/2007 Pharmacist United States
Primary
Concomitant
Procedural Complication Hospitalization 1/1/2006 Female 180 lb 12/14/2007 United States
Primary
Concomitant
Pyrexia 8/22/2007 Female 76 lb 12/14/2007 United States
Primary
Concomitant
Vomiting Hospitalization 10/4/2007 Female 12/14/2007 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2007 Male 135 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/4/2007 Female 1/11/2008 Physician United States
Primary
Concomitant
Drug Abuse Death 9/29/2006 47 Female 10/31/2007 Physician United States
Primary
Secondary
Concomitant
X-ray Of Pelvis And Hip Abnormal Hospitalization 1/1/2002 32 Female 150 lb 1/8/2008 United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 11/4/2007 47 Female 145 lb 1/10/2008 United States
Primary
Concomitant
Self-medication Death 32 Male 220 lb 1/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2006 46 Female 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Death 46 Female 1/21/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 46 Female 1/22/2008 Physician United States
Primary
Secondary
Drug Toxicity Death 1/1/2003 54 2/6/2008 Physician Canada
Primary
Secondary
Concomitant
Drug Toxicity Death 1/1/2003 54 2/6/2008 Physician Canada
Primary
Secondary
Concomitant
Nausea Death 1/6/2008 61 Male 165 lb 2/8/2008 United States
Primary
Concomitant
Respiratory Arrest Death 46 Female 2/5/2008 Physician United States
Primary
Secondary
Completed Suicide Death 46 Female 2/6/2008 Physician United States
Primary
Secondary
Paraesthesia Other Serious 40 Male 118 lb 11/28/2007 United Kingdom
Primary
Secondary
Urinary Tract Infection Other Serious 10/18/2007 46 Female 176 lb 2/12/2008 Other Health Professional United States
Primary
Concomitant
Cardio-respiratory Arrest Death 1/1/2006 46 Female 2/13/2008 Physician United States
Primary
Secondary
Wrong Technique In Drug Usage Process Other Serious 1/1/2007 Male 135 lb 2/19/2008 Physician United States
Primary
Secondary
Concomitant
Nausea Death 1/6/2008 61 Male 165 lb 2/27/2008 Other Health Professional United States
Primary
Concomitant
Inflammation Other Serious 11/1/2007 Male 161 lb 3/14/2008 Physician Belgium
Primary
Concomitant
Injection Site Irritation Hospitalization 1/1/2006 Female 180 lb 3/14/2008 United States
Primary
Concomitant
Pain 11/1/2007 Female 142 lb 3/15/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 11/3/2007 63 Female 229 lb 3/11/2008 Pharmacist United States
Primary
Concomitant
Completed Suicide Death 3/19/2008 Physician United States
Primary
Secondary
Stomach Discomfort Other Serious 12/1/2006 Male 3/26/2008 Lawyer United States
Primary
Concomitant
Ventricular Hypertrophy Life Threatening 3/7/2008 Female 3/28/2008 Consumer United States
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 3/7/2008 Female 4/11/2008 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death Male 4/14/2008 Other Health Professional United States
Primary
Secondary
Urinary Tract Infection Other Serious 10/18/2007 46 Female 176 lb 4/23/2008 Other Health Professional United States
Primary
Concomitant
Sensation Of Heaviness Hospitalization 3/12/2008 51 Female 4/14/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2006 50 Male 5/5/2008
Primary
Secondary
Concomitant
Protein Total Decreased Other Serious 1/1/2007 Male 5/13/2008 Physician United States
Primary
Concomitant
Middle Insomnia 11/1/2007 61 Female 194 lb 5/1/2008 Consumer United States
Primary
Concomitant
Sensation Of Heaviness Hospitalization 3/12/2008 51 Female 7/8/2008 Physician United States
Primary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 9/10/2008 Lawyer United States
Primary
Concomitant
Pain In Extremity 6/16/2008 Female 168 lb 9/12/2008 United States
Primary
Concomitant
Joint Swelling 7/1/2008 Female 180 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Drug Level Increased Other Serious 39 Male 11/11/2008 Physician Finland
Primary
Concomitant
Myocardial Infarction Other Serious 9/16/2008 63 Female 185 lb 11/17/2008 Other Health Professional United States
Primary
Concomitant
Memory Impairment Other Serious 7/1/2007 48 Female 175 lb 12/15/2008 Physician United States
Primary
Concomitant
Intentional Drug Misuse Death 1/1/2007 33 Male 1/6/2009 Other Health Professional United States
Primary
Secondary
Intentional Drug Misuse Death 1/1/2007 37 Male 1/6/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 25 Female 1/6/2009 Other Health Professional United States
Primary
Secondary
Non-small Cell Lung Cancer Hospitalization 8/19/2008 1/14/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Respiratory Arrest Death 38 Male 1/28/2009 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2007 23 Male 2/2/2009 Pharmacist United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2007 25 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2007 37 Male 2/2/2009 Pharmacist United States
Primary
Secondary
Wrong Technique In Drug Usage Process Death 33 Female 2/12/2009 United States
Primary
Secondary
Diarrhoea Hospitalization 1/19/2009 2/18/2009 Physician Argentina
Primary
Concomitant
Diarrhoea Hospitalization 1/19/2009 2/25/2009 Physician Argentina
Primary
Concomitant
Intentional Drug Misuse Death 37 Male 2/26/2009 Physician United States
Primary
Secondary
Wrong Technique In Drug Usage Process Death 33 Female 2/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Other Serious 16 Male 3/6/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Death 6/4/2008 Male 226 lb 4/9/2009 Other Health Professional United States
Primary
Concomitant
Adverse Drug Reaction Death Male 4/21/2009
Primary
Secondary
Concomitant
Death Death Male 4/21/2009
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/19/2009 5/5/2009 Physician Argentina
Primary
Concomitant
Haematemesis Other Serious 3/6/2008 60 Male 214 lb 5/21/2009 Other Health Professional United States
Primary
Concomitant
Propofol Infusion Syndrome Other Serious 36 Female 5/26/2009 Pharmacist United States
Primary
Concomitant
Gastrointestinal Perforation Hospitalization 5/27/2009 Male 138 lb 5/28/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 5/12/2009 Female 149 lb 6/5/2009 Physician Japan
Primary
Concomitant
Vomiting Neonatal Hospitalization 5/1/2007 Female 6 lb 6/5/2009 Physician Japan
Primary
Concomitant
Pneumoperitoneum Hospitalization 5/27/2009 Male 138 lb 6/8/2009 Other Health Professional United States
Primary
Concomitant
Troponin Increased Life Threatening 1/1/2007 37 Male 132 lb 6/15/2009 Physician United States
Primary
Secondary
Wrong Technique In Drug Usage Process Hospitalization 1/1/2008 Female 135 lb 6/24/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 18 Female 242 lb 6/25/2009 United States
Primary
Concomitant
Off Label Use Other Serious 1/1/2007 7/9/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Other Serious 2/1/2006 7/29/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/20/2009 Female 8/6/2009 Physician United States
Primary
Concomitant
Death Death 1/1/2009 36 Male 8/17/2009 Other Health Professional United States
Primary
Concomitant
Medication Error Death 9/3/2009 Physician United States
Primary
Secondary
Qrs Axis Abnormal Death 6/1/2008 Female 178 lb 9/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 1/1/2009 36 Male 9/9/2009 Other Health Professional United States
Primary
Concomitant
Sudden Death Death 1/11/2009 Male 214 lb 9/11/2009 Consumer United States
Primary
Secondary
Wrong Technique In Drug Usage Process Hospitalization 1/1/2006 Female 180 lb 9/12/2009 United States
Primary
Concomitant
Pain In Extremity 6/16/2008 Female 168 lb 9/12/2009 United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 5/12/2009 Female 149 lb 9/21/2009 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Required Intervention 10/28/2008 Male 202 lb 10/30/2008 Pharmacist United States
Primary
Concomitant
Ischaemic Stroke Death 6/1/2008 Female 178 lb 9/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2008 64 Male 138 lb 10/9/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/18/2007 46 Female 176 lb 10/23/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 57 Female 175 lb 10/22/2009 Consumer United States
Primary
Concomitant
Pulmonary Oedema Death Male 187 lb 11/6/2009 Consumer United States
Primary
Secondary
Lethargy Other Serious 7/13/2007 Male 11/30/2009 Physician United States
Primary
Concomitant
Ischaemic Stroke Death 6/1/2008 61 Female 178 lb 12/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor 1/1/2009 62 Female 203 lb 12/9/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Death 52 Female 95 lb 12/15/2009 Physician United States
Primary
Secondary
Concomitant

Drug Data