Alprazolam combined with Esomeprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Loss Of Consciousness Life Threatening 10/10/2005 Female 168 lb 10/12/2005 United States
Primary
Concomitant
Therapy Non-responder Death 46 Female 2/7/2006 Pharmacist United States
Primary
Secondary
Vomiting Other Serious 65 Female 159 lb 12/21/2005 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 7/28/2005 75 Female 138 lb 12/27/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 1/13/2006 43 Female 3/4/2006 France
Primary
Secondary
Concomitant
Syncope Hospitalization 12/28/2005 65 Female 3/31/2006 Switzerland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/20/2006 62 Male 4/19/2006 Pharmacist United States
Primary
Concomitant
Vomiting Required Intervention 11/23/2005 86 Female 12/5/2005 Pharmacist United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 2/7/2007 30 Female 187 lb 10/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/11/2007 48 Female 10/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/1/2007 54 Female 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Skin Burning Sensation Hospitalization 11/25/2004 60 Female 140 lb 12/3/2007 Consumer United States
Primary
Concomitant
Skin Exfoliation Other Serious 7/1/2007 86 Male 12/3/2007 Other Health Professional United States
Primary
Concomitant
Walking Aid User Other Serious 1/1/2007 Female 160 lb 3/21/2008 Consumer United States
Primary
Secondary
Concomitant
Subcutaneous Haematoma Required Intervention 12/5/2007 85 Male 4/22/2008 Other Health Professional France
Primary
Concomitant
Renal Failure Other Serious 4/23/2008 79 Female 134 lb 7/2/2008 Physician United States
Primary
Concomitant
Hallucination, Visual Hospitalization 9/6/2007 94 Female 193 lb 7/15/2008 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 5/17/2008 Female 7/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tachyarrhythmia Life Threatening 6/12/2008 72 Male 172 lb 8/26/2008 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 6/12/2008 72 Male 172 lb 9/2/2008 Physician Japan
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 68 Female 9/9/2008 Pharmacist Spain
Primary
Concomitant
Interacting
Staphylococcal Bacteraemia Other Serious 5/17/2008 Female 160 lb 9/23/2008 Physician United States
Primary
Secondary
Concomitant
Pyelonephritis Acute Hospitalization 7/13/2009 Female 8/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 64 Female 8/20/2009 Lawyer United States
Primary
Concomitant
Ischaemic Cardiomyopathy Hospitalization 8/2/2009 Female 9/24/2009 Physician France
Primary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Vomiting Life Threatening 9/15/2009 57 Male 11/6/2009 Consumer Denmark
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 11/23/2009 Pharmacist United States
Primary
Secondary
Interacting
Leukopenia Life Threatening 10/2/2009 58 Male 12/7/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/25/2009 Male 140 lb 12/11/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/30/2009 Female 119 lb 12/24/2009 Physician France
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2008 59 Male 1/8/2010 Physician United States
Primary
Secondary
Overdose Death 59 Male 1/22/2010 Physician United States
Primary
Secondary
Drug Toxicity Death 59 Male 1/25/2010 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 12/1/2009 59 Male 2/1/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 59 Male 2/1/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 59 Male 2/2/2010 Physician United States
Primary
Secondary
Weight Decreased Hospitalization 11/30/2009 Male 2/19/2010 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 59 Male 2/23/2010 Physician United States
Primary
Secondary
Pulmonary Embolism Hospitalization 2/15/2010 Male 158 lb 2/18/2010 United States
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Other Serious Male 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 59 Male 2/26/2010 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 59 Male 3/3/2010 Other Health Professional United States
Primary
Secondary
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 59 Male 3/3/2010 Physician United States
Primary
Secondary
Tooth Fracture Other Serious 10/3/2006 Male 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/2/2009 Male 386 lb 3/1/2010 Consumer United States
Primary
Concomitant
Tooth Fracture Other Serious 10/3/2006 Male 3/25/2010 Physician United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 10/3/2006 Male 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 1/1/2008 59 Male 4/6/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 8/17/2006 54 Male 269 lb 4/23/2010 Physician Belgium
Primary
Concomitant
Walking Aid User Other Serious 10/3/2006 73 Male 4/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Axonal Neuropathy Disability 11/13/2009 53 Male 214 lb 5/11/2010 Physician France
Primary
Secondary
Concomitant
Walking Aid User Other Serious 10/3/2006 73 Male 5/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhage Intracranial Other Serious 2/1/2008 77 Female 5/25/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 6/22/2010 Lawyer United States
Primary
Concomitant
Walking Aid User Other Serious 10/3/2006 73 Male 6/25/2010 United States
Primary
Secondary
Concomitant
Axonal Neuropathy Disability 11/13/2009 53 Male 214 lb 9/20/2010 Physician France
Primary
Secondary
Concomitant
Subileus Hospitalization 6/24/2008 50 Female 10/8/2010 Physician France
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 10/3/2006 73 Male 10/14/2010 United States
Primary
Secondary
Concomitant
Metastases To Bone Other Serious 2/10/2008 77 Female 10/15/2010 Lawyer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2009 47 Female 10/18/2010 Other Health Professional France
Primary
Secondary
Concomitant
Hemiparesis Other Serious 7/8/2010 85 Female 10/4/2010 Portugal
Primary
Concomitant
Hypokalaemia Hospitalization 7/14/2010 30 Female 183 lb 11/4/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 12/3/2007 78 Female 150 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 187 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2009 47 Female 12/14/2010 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/15/2008 60 Male 12/15/2010 Other Health Professional United States
Primary
Concomitant
Cardio-respiratory Arrest Death 21 Female 1/4/2011 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 1/1/2009 21 Female 1/4/2011 Physician United States
Primary
Secondary
Intentional Drug Misuse Other Serious 1/1/2009 21 Female 1/6/2011 Physician United States
Primary
Secondary
Completed Suicide Death 21 Female 1/20/2011 Physician United States
Primary
Secondary
Hemiparesis Other Serious 7/8/2010 85 Female 12/20/2010 Portugal
Primary
Concomitant
Pneumonia Life Threatening 8/16/2006 54 Male 269 lb 1/21/2011 Physician Belgium
Primary
Concomitant
Cardio-respiratory Arrest Death 1/21/2011 Physician United States
Primary
Secondary
Cholestasis Hospitalization 10/26/2009 15 Male 88 lb 1/30/2011 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 21 Female 2/7/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 1/1/2009 21 Female 1/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 21 Female 1/20/2011 United States
Primary
Secondary
Cardiac Arrest Death 21 Female 2/5/2011 Physician United States
Primary
Secondary
Completed Suicide Death 21 Female 3/3/2011 Other Health Professional United States
Primary
Secondary
Jaundice Hospitalization 10/26/2009 15 Male 88 lb 3/25/2011 Consumer France
Primary
Secondary
Concomitant
Atrial Fibrillation Death 12/1/2010 87 Male 3/29/2011 Other Health Professional France
Primary
Concomitant
Non-small Cell Lung Cancer Death 3/3/2011 56 Female 104 lb 5/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Loss Of Consciousness Death 9/30/2011 70 Female 245 lb 10/12/2011 Physician United States
Primary
Concomitant
Death Death 9/30/2011 70 Female 245 lb 10/17/2011 Physician United States
Primary
Concomitant
Death Death 9/30/2011 70 Female 245 lb 10/24/2011 Physician United States
Primary
Concomitant
Anaemia Life Threatening 69 Male 187 lb 10/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Depression Hospitalization 9/27/2006 43 Male 11/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 9/30/2011 70 Female 245 lb 11/10/2011 Physician United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 1/31/2011 57 Female 11/15/2011 Physician United States
Primary
Concomitant
Depression Other Serious 8/19/2011 52 Female 282 lb 12/6/2011 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 2/25/2008 86 Female 146 lb 1/20/2012 Physician Spain
Primary
Concomitant
Interacting
Neurosis Hospitalization 31 Female 1/20/2012 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Death Death 9/30/2011 70 Female 245 lb 2/29/2012 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 7/20/2011 54 Female 200 lb 3/21/2012 United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 7/5/2010 55 Male 4/9/2012 Physician United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Death 7/5/2010 55 Male 5/3/2012 Physician United States
Primary
Secondary
Concomitant
Vomiting Death 4/17/2012 55 Male 6/6/2012 Other Health Professional France
Primary
Secondary
Concomitant
Depression Hospitalization 4/17/2012 55 Male 6/20/2012 Other Health Professional France
Primary
Secondary
Concomitant
Chest Discomfort Disability Male 240 lb 6/14/2012 Lawyer United States
Primary
Concomitant
Abdominal Pain Other Serious 4/7/2011 52 Female 133 lb 6/25/2012 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 4/7/2011 52 Female 133 lb 6/29/2012 Physician United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 4/8/2012 65 Male 7/3/2012 Physician Ireland
Primary
Secondary
Concomitant
Nausea Hospitalization 3/27/2012 59 Female 216 lb 7/26/2012 Physician United States
Primary
Concomitant
Respiratory Disorder Hospitalization 7/27/2009 42 Male 12/17/2012 Physician Us
Primary
Secondary
Concomitant
Pneumonia Aspiration Other Serious 10/2011 69 Female 185 lb 4/22/2013 Other Health Professional Us
Primary
Concomitant
Pulmonary Embolism Life Threatening 4/8/2012 65 Male 10/22/2012 Physician Ie
Primary
Secondary
Concomitant
Appendicitis Other Serious 7/20/2012 62 Female 9/14/2012 Consumer Us
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 8/22/2012 67 Male 10/16/2012 Consumer Us
Primary
Concomitant
Septic Shock Other Serious 10/1/2012 57 Female 231 lb 1/28/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 3/17/2012 55 Female 152 lb 2/22/2013 Physician In
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 78 Female 1/25/2013 Physician Fr
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 2/22/2012 66 Male 1/8/2013 Consumer Gb
Primary
Concomitant
Suicide Attempt Other Serious 12/22/2012 50 Female 1/29/2013 Consumer Ch
Primary
Secondary
Sopor Hospitalization 1/2/2013 13 Female 2/7/2013 Other Health Professional It
Primary
Secondary
Sopor Hospitalization 1/2/2013 Female 3/14/2013 Consumer It
Primary
Secondary
Syncope Hospitalization 1/13/2013 Female 147 lb 2/28/2013 Physician Us
Primary
Secondary
Concomitant
Sopor Hospitalization 1/2/2013 13 Female 126 lb 3/12/2013 Physician It
Primary
Secondary
Syncope Hospitalization 1/13/2013 79 Female 147 lb 2/11/2013 Physician Us
Primary
Secondary
Concomitant
Sopor Hospitalization 1/2/2013 14 Female 2/11/2013 Physician It
Primary
Secondary
Respiratory Failure Hospitalization 2012 62 Female 159 lb 4/23/2013 Other Health Professional Nl
Primary
Concomitant
Mouth Haemorrhage Hospitalization 12/18/2012 64 Male 3/18/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/25/2013 66 Male 197 lb 3/26/2013 Consumer Us
Primary
Concomitant
Weight Decreased Other Serious 12/2011 46 Female 108 lb 9/8/2012 Consumer Us
Primary
Secondary
Concomitant
Wheezing Hospitalization 12/2012 70 Female 141 lb 4/5/2013 Br
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/30/2012 49 Male 179 lb 4/18/2013 Physician Ie
Primary
Concomitant
Drug Ineffective Other Serious 3/29/2013 53 Female 299 lb 4/19/2013 Other Health Professional Us
Primary
Concomitant
Infusion Related Reaction Hospitalization 6/5/2013 48 Female 8/13/2013 Physician It
Primary
Secondary
Concomitant
Urine Abnormality Hospitalization 6/2013 61 Male 11/1/2013 Consumer Fr
Primary
Secondary
Concomitant
Somnolence Hospitalization 6/8/2013 76 Male 6/26/2013 Other Health Professional Fr
Primary
Concomitant
Respiratory Distress Hospitalization 5/28/2013 67 Female 6/27/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 5/28/2013 67 Female 6/28/2013 Physician Fr
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 6/19/2013 90 Female 7/1/2013 Consumer Gt
Primary
Concomitant
Malaise Hospitalization 2013 82 Male 7/31/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Toxic Nodular Goitre Other Serious 9/27/2012 41 Male 190 lb 8/27/2013 Physician Tw
Primary
Concomitant
Syncope Hospitalization 87 Female 9/24/2013 Physician Fr
Primary
Interacting
Syncope Hospitalization 87 Female 9/27/2013 Consumer Fr
Primary
Secondary
Interacting
Staphylococcal Infection Hospitalization 9/3/2013 NotSpecified 7/6/2014 Consumer Us
Primary
Concomitant
Vestibular Disorder Disability 35 Female 10/14/2013 Other Health Professional Us
Primary
Secondary
Interacting
Syncope Hospitalization 87 Female 10/4/2013 Physician Fr
Primary
Interacting
Hyponatraemic Encephalopathy Hospitalization 8/3/2013 76 Female 10/10/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/19/2013 58 Female 119 lb 12/11/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Hepatocellular Injury Hospitalization 8/27/2013 69 Male 10/11/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Gastroenteritis Viral Hospitalization 8/21/2011 54 Female 10/11/2013 Physician Es
Primary
Secondary
Concomitant
Vestibular Disorder Other Serious 35 Female 10/15/2013 Consumer Us
Primary
Secondary
Interacting
Vestibular Disorder Disability 35 Female 10/21/2013 Other Health Professional Us
Primary
Secondary
Interacting

Drug Data