Alprazolam combined with Digoxin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypoglycaemia Death 7/18/2003 93 Male 1/5/2006 Other Health Professional Canada
Primary
Concomitant
Syncope Other Serious 7/26/2005 Male 2/3/2006 Puerto Rico
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2005 81 Male 120 lb 2/2/2006 Physician United States
Primary
Concomitant
Pleural Effusion Other Serious 7/26/2005 Male 215 lb 2/16/2006 Puerto Rico
Primary
Concomitant
Weight Decreased Other Serious 3/26/2004 Male 110 lb 3/17/2006 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 12/30/2005 74 Male 154 lb 4/5/2006 Other Health Professional France
Primary
Concomitant
Interacting
Thrombocytopenia Other Serious 7/26/2005 Male 215 lb 4/7/2006 Puerto Rico
Primary
Concomitant
Vomiting 6/1/2005 40 Female 131 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/30/2005 74 Male 154 lb 5/2/2006 Other Health Professional France
Primary
Concomitant
Interacting
Mesenteric Vein Thrombosis Life Threatening 12/28/2005 Female 94 lb United States
Primary
Concomitant
Myocardial Infarction Hospitalization 9/21/2004 80 Male 165 lb 5/15/2006 Lawyer United States
Primary
Concomitant
Hypocalcaemia Hospitalization 12/18/2005 71 Male 3/13/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/23/2006 86 Female 6/5/2006 Consumer Mexico
Primary
Concomitant
Unevaluable Event Hospitalization 3/13/2006 94 Female 6/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Incontinence 96 Female 5/5/2006 Consumer United States
Primary
Secondary
Concomitant
Viral Upper Respiratory Tract Infection Death 9/7/2005 73 Male 171 lb 7/21/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Hypotension Hospitalization 5/16/2006 87 Male 172 lb 8/4/2006 Physician France
Primary
Concomitant
Malaise Hospitalization 6/1/2006 82 Female 154 lb 8/10/2006 Physician France
Primary
Secondary
Concomitant
Skin Swelling Other Serious 1/1/2006 77 Male 158 lb 7/19/2006 United States
Primary
Concomitant
Venous Thrombosis Other Serious 4/1/2006 55 Female 105 lb 8/14/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 2/12/2005 34 Female 158 lb 8/22/2006 Consumer United States
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 8/9/2006 69 Male 155 lb 8/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/13/2006 87 Male 172 lb 8/25/2006 Physician France
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 8/14/2006 81 Female 121 lb 8/30/2006 Pharmacist United States
Primary
Concomitant
Rib Fracture Hospitalization 5/13/2006 87 Male 172 lb 9/13/2006 Physician France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/25/2006 Male 203 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 1/1/2005 65 Female 10/17/2006 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2005 65 Female 180 lb 11/1/2006 United States
Primary
Concomitant
Blood Viscosity Increased Hospitalization 74 Female 11/13/2006 Physician Belgium
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 5/21/2005 74 Male 11/15/2006 United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 9/1/2006 64 Male 11/21/2006 France
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/30/2007 61 Female 105 lb 3/6/2007 Physician United States
Primary
Concomitant
Fatigue Other Serious 3/23/2007 Male 3/27/2007 Pharmacist United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 1/26/2007 82 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Vomiting 5/1/2007 81 Female 7/6/2007 Consumer United States
Primary
Concomitant
Off Label Use Other Serious 6/1/2007 56 Female 95 lb 7/13/2007 Physician Brazil
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 6/1/2007 56 Female 95 lb 7/26/2007 Physician Brazil
Primary
Secondary
Concomitant
Viral Infection Hospitalization 3/1/2007 66 Male 7/2/2007 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 6/1/2007 56 Female 95 lb 8/20/2007 Physician Brazil
Primary
Secondary
Concomitant
Hepatitis Cholestatic Other Serious 8/16/2006 92 Female 9/20/2007 Other Health Professional Italy
Primary
Concomitant
Back Pain 4/26/2007 70 Female 223 lb 9/20/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 240 lb 9/28/2007 Other Health Professional
Primary
Concomitant
Dyspnoea Hospitalization 7/10/2007 51 Female 10/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis Cholestatic Other Serious 8/16/2006 92 Female 10/18/2007 Other Health Professional Italy
Primary
Concomitant
Wheezing 69 Female 10/25/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 240 lb 11/19/2007 Physician United States
Primary
Concomitant
Hepatitis Cholestatic Other Serious 8/16/2006 92 Female 11/20/2007 Other Health Professional Italy
Primary
Concomitant
Hyperglycaemia Other Serious 54 Male 165 lb 11/30/2007 Consumer Brazil
Primary
Secondary
Concomitant
Hepatitis Toxic Hospitalization 12/23/2006 92 Female 12/7/2007
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 8/17/2007 84 Female 12/4/2007 Pharmacist United States
Primary
Secondary
Concomitant
Hepatitis Toxic Hospitalization 12/23/2006 92 Female 12/3/2007 Spain
Primary
Secondary
Weight Increased Other Serious 1/1/2007 Female 230 lb 1/2/2008 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2002 52 Female 150 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 1/24/2008 Male 148 lb 2/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Panic Attack Other Serious 1/1/2007 2/12/2008 Consumer Portugal
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/24/2008 65 Male 148 lb 2/12/2008 Physician United States
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 10/7/2007 74 Female 2/27/2008 Other Health Professional Germany
Primary
Concomitant
Interacting
Myopathy Hospitalization 7/1/2007 Female 3/9/2008 Physician Australia
Primary
Secondary
Concomitant
Vertigo Hospitalization 11/6/2007 89 Female 4/4/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Life Threatening 3/11/2008 60 Female 190 lb 4/14/2008 Physician Switzerland
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 10/7/2007 74 Female 4/24/2008 Other Health Professional Germany
Primary
Concomitant
Interacting
Vomiting Other Serious 8/1/2007 Female 245 lb 5/2/2008 Physician United States
Primary
Concomitant
Hepatitis Cholestatic Other Serious 8/16/2006 92 Female 4/29/2008 Italy
Primary
Concomitant
Vascular Rupture Other Serious 1/1/2007 78 Female 5/8/2008 Consumer Argentina
Primary
Concomitant
Hepatitis Cholestatic Other Serious 8/16/2006 92 Female 5/8/2008 Italy
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 3/11/2008 59 Female 190 lb 5/23/2008 Physician Switzerland
Primary
Secondary
Concomitant
Tremor Other Serious 3/1/2008 65 Male 206 lb 5/21/2008 United States
Primary
Concomitant
Thrombosis Other Serious 5/1/2008 Male 166 lb 6/12/2008 Pharmacist United States
Primary
Concomitant
Vena Cava Injury Death 2/8/2008 Female 180 lb 6/10/2008 Pharmacist United States
Primary
Secondary
Concomitant
Pain 4/1/2008 Male 180 lb 6/13/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 6/28/2008 71 Female 74 lb 7/1/2008 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 4/21/2008 66 Male 155 lb 7/10/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 49 Male 250 lb 8/12/2008 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 2/14/2008 78 Male 229 lb 8/14/2008 Pharmacist United States
Primary
Concomitant
Pharyngeal Oedema 12/1/2007 Female 181 lb 8/27/2008 Consumer United States
Primary
Concomitant
Intestinal Polyp Other Serious 6/21/2008 Female 126 lb 8/29/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 4/21/2008 66 Male 155 lb 8/27/2008 United States
Primary
Concomitant
Vomiting Hospitalization 5/9/2008 78 Female 155 lb 9/2/2008 Pharmacist United States
Primary
Concomitant
Hypoxia Death 4/23/2008 82 Female 103 lb 9/3/2008 United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 7/2/2008 Male 233 lb 9/11/2008 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 4/21/2008 66 Male 155 lb 9/10/2008 United States
Primary
Concomitant
Renal Impairment Hospitalization 71 Female 208 lb 9/12/2008 United States
Primary
Concomitant
Chest Pain Hospitalization Female 194 lb 10/21/2008 Consumer United States
Primary
Concomitant
Nausea Death Male 11/4/2008 United States
Primary
Concomitant
Anaemia Other Serious 6/21/2008 Female 126 lb 11/14/2008 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 71 Female 11/5/2008 United States
Primary
Concomitant
Renal Failure Hospitalization 12/20/2007 80 Male 190 lb 9/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 6/23/2008 84 Female 11/25/2008 Physician France
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 9/1/2008 51 Female 115 lb 12/3/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 95 Female 100 lb 12/10/2008 United States
Primary
Concomitant
Nervousness 85 Female 156 lb 12/17/2008 Consumer United States
Primary
Concomitant
Urine Bilirubin Increased Other Serious 7/10/2008 Male 176 lb 12/19/2008 United States
Primary
Concomitant
Hepatitis Toxic Hospitalization 12/23/2006 92 Female 12/29/2008 Pharmacist
Primary
Secondary
Product Quality Issue Hospitalization 5/7/2008 71 Female 106 lb 12/22/2008 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage 10/27/2008 83 Female 12/15/2008 United States
Primary
Concomitant
Cardiac Arrest Death 1/2/2009 Male 157 lb 1/13/2009 Physician Thailand
Primary
Concomitant
Syncope Death 9/18/2008 75 Male 1/9/2009 Consumer United States
Primary
Concomitant
Urticaria Other Serious 12/26/2008 76 Female 118 lb 1/7/2009 Consumer United States
Primary
Concomitant
Hepatitis Toxic Hospitalization 12/23/2006 92 Female 2/6/2009 Pharmacist
Primary
Secondary
Thrombocytopenia Hospitalization 1/21/2009 Male 174 lb 2/11/2009 Physician Argentina
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 8/29/2007 84 Female 2/18/2009 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 9/1/2008 51 Female 115 lb 3/9/2009 Pharmacist United States
Primary
Secondary
Concomitant
Death Death Female 3/30/2009 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 77 Female 3/26/2009 Physician Italy
Primary
Concomitant
Death Death 4/15/2009 Female 102 lb 4/27/2009 Consumer United States
Primary
Concomitant
Death Death 4/15/2009 Female 102 lb 5/1/2009 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 Female 222 lb 5/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Death 1/2/2009 Male 157 lb 5/8/2009 Physician Thailand
Primary
Concomitant
Visual Impairment Other Serious 67 Female 5/6/2009 United States
Primary
Concomitant
Underdose Other Serious 1/1/2008 68 Female 223 lb 5/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Death 4/15/2008 Female 5/7/2009 United States
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2002 Female 222 lb 5/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Cataract Other Serious 5/1/2007 Female 5/18/2009 Consumer United States
Primary
Secondary
Concomitant
Death Death 4/13/2009 Female 118 lb 5/18/2009 Consumer United States
Primary
Concomitant
Vertigo Other Serious 66 Female 5/13/2009 Lawyer United States
Primary
Concomitant
Underdose Other Serious 1/1/2008 68 Female 223 lb 5/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 8/29/2007 84 Female 5/24/2009 United States
Primary
Concomitant
Pneumonia Death 4/13/2009 Female 118 lb 6/9/2009 Physician United States
Primary
Concomitant
Viral Cardiomyopathy Other Serious 3/14/2006 32 Male 288 lb 6/5/2009 United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 66 Female 6/5/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 64 Male 179 lb 6/5/2009 Lawyer United States
Primary
Concomitant
Hypoglycaemia Hospitalization 12/22/2008 Male 6/17/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 Female 222 lb 6/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Off Label Use Hospitalization 1/1/2007 Female 123 lb 6/22/2009 Consumer United States
Primary
Concomitant
Renal Failure Life Threatening 57 Female 6/17/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 9/1/2008 51 Female 115 lb 6/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2008 84 Female 113 lb 6/22/2009 United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 3/23/2009 Male 301 lb 6/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Cardiomyopathy Other Serious 3/14/2006 32 Male 288 lb 6/26/2009 United States
Primary
Concomitant
Injury Death 71 Male 6/29/2009 Physician United States
Primary
Concomitant
Procedural Pain Hospitalization 5/10/2009 73 Male 245 lb 7/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 66 Female 7/1/2009 Lawyer United States
Primary
Concomitant
Ventricular Fibrillation Death 8/29/2007 84 Female 7/1/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Life Threatening 57 Female 7/1/2009 Lawyer United States
Primary
Concomitant
Traumatic Lung Injury Other Serious 3/14/2006 32 Male 288 lb 7/7/2009 United States
Primary
Concomitant
Wound Secretion Hospitalization 62 Female 7/12/2009 United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2002 52 Female 140 lb 7/16/2009 United States
Primary
Concomitant
Surgery Death 73 Female 7/13/2009 United States
Primary
Concomitant
Injury Death 62 Male 7/13/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 59 Female 7/13/2009 Lawyer United States
Primary
Concomitant
Ventricular Fibrillation Death 8/29/2007 84 Female 7/13/2009 Lawyer United States
Primary
Concomitant
Pain In Extremity Death 71 Male 7/13/2009 United States
Primary
Concomitant
Trigger Finger Other Serious 5/1/2007 Female 7/20/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 68 Female 7/15/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 74 Male 7/15/2009 Lawyer United States
Primary
Concomitant
Serositis Other Serious 1/1/2007 Female 123 lb 7/20/2009 Consumer United States
Primary
Concomitant
Multi-organ Failure Hospitalization 3/30/2009 72 Male 159 lb 7/17/2009 Physician France
Primary
Concomitant
Ventricular Fibrillation Death 8/29/2007 82 Female 7/17/2009 United States
Primary
Concomitant

Drug Data